The changing context and increasing professionalization in higher education have ushered in challenges for liberal arts education worldwide. Situated this discourse in the context of Chinese universities, this paper explores Why do we need a liberal arts education that has been accused of being elitist in the twenty first century? Should an effective or ideal liberal arts education evolve with time and context? If yes, what needs to be taken into account to conceptualize a twenty first century model of liberal (...) arts education? How is a twenty first century liberal arts education defined and featured at Chinese universities and elsewhere? Drawing on an analytical framework constructed with the German concept of Bildung and the Confucian perspective on knowledge, this paper contends that a twenty first century liberal arts education for universities in China and elsewhere needs to absorb meta changes and movements in society at home and around the world, while ideally rooted in a knowledge tradition respectively. Specifically, it should comprise three essential pillars: humanism education, cognitive education, and global education. (shrink)

Zha Changping takes inspiration from Western art theories and applies them to a contemporary Chinese context. The article has an ontological perspective, discussing how the concept of “relational aesthetics” manifests in Chinese contemporary art. It also discusses its relation to the history of ideas. The focus is on art, but the ontological perspectives on creation and humanity are universal.

The bamboo slip essay Hengxian 恒先 is historically valuable because it serves to further the ontological understanding and comprehension of issues related to the existence of the universe from the perspective of Laozi's Daoist thought. Hengxian explores important propositions such as how "Qi originated and activated itself and "they came out of the same source but differed in nature" from several aspects. The idea that "Hengxian is ' being' without any defmiteness" responds to the issue of the relationship of difference (...) and identity of all things in the world, and thus examines the interdependent relationships between subjects and objects. It proposes that humans can further understand the existence of the universe through cognitive activities and practices such as "analysis and comparison" in which objective realities are checked. The issues discussed in Hengxian are consistent with Laozi's Dao de jing, the works of Zhuangzi, Huangdi sijing 黄帝四经 (The Four Classics from the Emperor Yellow) and other Daoist works, and deserve significant attention. /// 摘要竹书 "恒先" 的历史价值在于以存在论的立场，深化了老子开创的道家思想 学说对于宇宙存在问题的认识理解。"恒先无有" 因通过 "气是自生自作" 与 "同 出而异性" 等重要命题的多方面阐释，回答了宇宙万物差别与同一关系问题，并且 以此为依据考察了主客体之间的依存关系，认为人类可以通过 "校比" 的认识实践 活动，与客观存在相对照检验，实现对宇宙存在的洞察。所论与老子 "道德经" 以 及庄学、"黄帝四经" 等多有一致之处，非常值得重视。. (shrink)

Motion pose capture technology can effectively solve the problem of difficulty in defining character motion in the process of 3D animation production and greatly reduce the workload of character motion control, thereby improving the efficiency of animation development and the fidelity of character motion. Motion gesture capture technology is widely used in virtual reality systems, virtual training grounds, and real-time tracking of the motion trajectories of general objects. This paper proposes an attitude estimation algorithm adapted to be embedded. The previous (...) centralized Kalman filter is divided into two-step Kalman filtering. According to the different characteristics of the sensors, they are processed separately to isolate the cross-influence between sensors. An adaptive adjustment method based on fuzzy logic is proposed. The acceleration, angular velocity, and geomagnetic field strength of the environment are used as the input of fuzzy logic to judge the motion state of the carrier and then adjust the covariance matrix of the filter. The adaptive adjustment of the sensor is converted to the recognition of the motion state. For the study of human motion posture capture, this paper designs a verification experiment based on the existing robotic arm in the laboratory. The experiment shows that the studied motion posture capture method has better performance. The human body motion gesture is designed for capturing experiments, and the capture results show that the obtained pose angle information can better restore the human body motion. A visual model of human motion posture capture was established, and after comparing and analyzing with the real situation, it was found that the simulation approach reproduced the motion process of human motion well. For the research of human motion recognition, this paper designs a two-classification model and human daily behaviors for experiments. Experiments show that the accuracy of the two-category human motion gesture capture and recognition has achieved good results. The experimental effect of SVC on the recognition of two classifications is excellent. In the case of using all optimization algorithms, the accuracy rate is higher than 90%, and the final recognition accuracy rate is also higher than 90%. In terms of recognition time, the time required for human motion gesture capture and recognition is less than 2 s. (shrink)

ObjectivesSeveral studies have examined the effects of repetitive transcranial magnetic stimulation (rTMS) on associative memory (AM) but findings were inconsistent. Here, we aimed to test whether twice-daily rTMS could significantly improve AM.MethodsIn this single-blind, sham-controlled experiment, 40 participants were randomized to receive twice-daily sham or real rTMS sessions for five consecutive days (a total of 16,000 pulses). The stimulation target in left inferior parietal lobule (IPL) exhibiting peak functional connectivity to the left hippocampus was individually defined for each participant. Participants (...) completed both a picture-cued word association task and Stroop test at baseline and 1 day after the final real or sham rTMS session. Effects of twice-daily rTMS on AM and Stroop test performance were compared using two-way repeated measures analysis of variance with main factors Group (real vs. sham) and Time (baseline vs. post-rTMS).ResultsThere was a significant Group × Time interaction effect. AM score was significantly enhanced in the twice-daily real group after rTMS, but this difference could not survive the post hoc analysis after multiple comparison correction. Further, AM improvement in the twice-daily real group was not superior to a previously reported once-daily rTMS group receiving 8,000 pulses. Then, we combined the twice- and once-daily real groups, and found a significant Group × Time interaction effect. Post hoc analysis indicated that the AM score was significantly enhanced in the real group after multiple comparisons correction.ConclusionOur prospective experiment did not show significant rTMS effect on AM, but this effect may become significant if more participants could be recruited as revealed by our retrospective analysis. (shrink)

Despite the bombardment of AI ethics frameworks (AIEFs) published in the last decade, it is unclear which of the many have been adopted in the industry. What is more, the sheer volume of AIEFs without a clear demonstration of their effectiveness makes it difficult for businesses to select which framework they should adopt. As a first step toward addressing this problem, we employed four different existing frameworks to assess AI ethics concerns of a real-world AI system. We compared the experience (...) of applying the AIEFs from the perspective of (a) a third-party auditor conducting an AI ethics risk assessment for the company, and (b) the company receiving the audit outcomes. Our results suggest that the feel-good factor of doing an assessment is common across the AIEFs that can take anywhere between 1.5 and 20 h to complete. However, each framework provides different benefits (e.g., issue discovery vs. issue monitoring) and is likely best used in conjunction with one another at different stages of an AI development process. As such, we call on the AI ethics community to better specify the suitability and expected benefits of existing frameworks to enable better adoption of AI ethics practice in the industry. (shrink)

本书内容包括:论计算机网络犯罪现状、民法中的法律行为概念之界定、浅论国家控制力与行政法改革、从国际法谈两岸关系等。.

At present, the news broadcast system using mobile network on the market provides the basic functions required by TV stations, but there are still many problems and shortcomings. In view of the main problems existing in the current system and combined with the actual needs of current users, this paper has preliminarily developed a news broadcast system based on 5G Live. The card frame adaptive strategy significantly improves the user experience by using gradual video frame buffering technology. Hardware codec technology (...) significantly reduces the consumption of system resources; H.264 high-compression algorithm can reduce network bandwidth by 50% compared with MPEG-2 and MPEG-4 without a significant change in image quality. At the same time, the use of mobile video acquisition terminals in the system not only solves the problem that satellite broadcast vehicles cannot reach the site due to the lack of roads but also greatly reduces the cost of early deployment and late maintenance of the news broadcast system. This paper studies the card frame adaptive strategy, the system resource consumption reduction solution, and the deployment scheme of the mobile video and audio transmission terminal, which is of great significance to improve the design and research of the news broadcast system under the wireless network application and also has certain reference value for the design of other broadcasting and television solutions. (shrink)

The bamboo slip essay Hengxian æ’å ˆis historically valuable because it serves to further the ontological understanding and comprehension of issues related to the existence of the universe from the perspective of Laozi’s Daoist thought. Hengxian explores important propositions such as how Qi originated and activated itself and they came out of the same source but differed in nature from several aspects. The idea that Hengxian is ‘being’ without any definiteness responds to the issue of the relationship of difference and (...) identity of all things in the world, and thus examines the interdependent relationships between subjects and objects. It proposes that humans can further understand the existence of the universe through cognitive activities and practices such as analysis and comparison in which objective realities are checked. The issues discussed in Hengxian are consistent with Laozi’s Dao de jing, the works of Zhuangzi, Huangdi sijing 黄帝四经 (The Four Classics from the Emperor Yellow) and other Daoist works, and deserve significant attention. (shrink)

Understanding and solving the psychological health problems of college students have become a focus of social attention. Complex networks have become important tools to study the factors affecting psychological health, and the Gaussian graphical model is often used to estimate psychological networks. However, previous studies leave some gaps to overcome, including the following aspects. When studying networks of subpopulations, the estimation neglects the intrinsic relationships among subpopulations, leading to a large difference between the estimated network and the real network. Because (...) of the high cost, previous psychological surveys often have a small sample size, and the psychological description is insufficient. Here, the intrinsic connections among multiple tasks are used, and multitask machine learning is applied to develop a multitask Gaussian graphical model. The psychological networks of the population and subpopulations are estimated based on psychological questionnaire data. This study is the first to apply a psychological network to such a large-scale college student psychological analysis, and we obtain some interesting results. The model presented here is a dynamic model based on complex networks which predicts individual behavior and provides insight into the intrinsic links among various symptoms. (shrink)

This study focuses on the evolution and preservation of the cultural heritage of the Ti-Tzu ten-hole bamboo flute in Sichuan Province, China. For collecting data, the researchers conducted interviews and observations. The results of the study show that Shen Wenyi's original work resulted in the invention of bamboo flutes with seven, nine, and ten holes, which are significant findings. These developments resolved issues with pitch discrepancies and broadened the range of playing techniques, influencing the flute's cultural importance and musical repertoire. (...) The study also emphasizes educational endeavors, group development, and textbook creation to safeguard and advance the flute tradition. It highlights the lasting impact and constant evolution of the Ti-Tzu ten-hole bamboo flute as a representation of cultural heritage and a source of pride in Sichuan Province. (shrink)

Due to extensive product differentiation and the personalized aesthetic needs of consumers, modern enterprises need different expressions of information to attract consumers’ interest and improve their purchase intention. This study draws from the elaboration likelihood model, anchoring theory, and media richness theory to explore how the expression of advertised information can be effectively matched to the product type to enhance consumers’ purchase intention. The mediating effect of information-processing fluency and moderating effect of consumers’ personal involvement on this relationship is also (...) explored. Data from experiments and questionnaires involving 1,292 participants were analyzed. The results show that direct expression of advertised information is more suitable for advertising search products, while metaphorical expressions of advertised information are more suitable for advertising experience products. These combinations of product type and expression of advertised information can effectively improve consumers’ purchase intention. Meanwhile, the main combined effect of the product type and expression of advertised information is mediated by consumers’ information-processing fluency, and moderated by consumers’ personal involvement positively. (shrink)

The sampling-based motion planner is the mainstream method to solve the motion planning problem in high-dimensional space. In the process of exploring robot configuration space, this type of algorithm needs to perform collision query on a large number of samples, which greatly limits their planning efficiency. Therefore, this paper uses machine learning methods to establish a probabilistic model of the obstacle region in configuration space by learning a large number of labeled samples. Based on this, the high-dimensional samples’ rapid collision (...) query is realized. The influence of number of Gaussian components on the fitting accuracy is analyzed in detail, and a self-adaptive model training method based on Greedy expectation-maximization algorithm is proposed. At the same time, this method has the capability of online updating and can eliminate model fitting errors due to environmental changes. Finally, the model is combined with a variety of sampling-based motion planners and is validated in multiple sets of simulations and real world experiments. The results show that, compared with traditional methods, the proposed method has significantly improved the planning efficiency. (shrink)

There has been much research into teacher beliefs about teaching and learning as seen in the general teacher education literature. In the field of language teacher education, this line of research has been evolving, with the recent trend being streamlined into “teacher cognition” as a generic or umbrella term. Despite increasing amounts of research output so far, research into foreign language teachers’ cognitions about their own teaching and decision-making is still insufficient, particularly with regard to university-level English-as-a-foreign-language (EFL) teachers in (...) China. Drawing on Vygotsky’s Sociocultural Theory, this qualitative research focused on EFL teachers’ cognitions about form-focused instruction in Chinese university settings. It intended to discover how teachers’ cognitions changed when they were expected to teach in actual classrooms and what factors contributed to these changes. Data collected from four teacher-participants through semi-structured interviews, classroom observations and follow-up stimulated recall interviews showed participants’ support forfocus-on-forminstruction, which means they not only paid attention to the grammatical form of the language but also to the meaning it is intended to convey. However, data also showed that the teacher-participants shifted fromfocus-on-formtofocus-on-formSinstruction in actual teaching, which suggests that they might have realized the challenges of carrying out teaching activities surroundingfocus-on-formand would like to take an easier approach by only teaching the grammar of the language byfocusing on formS. Such incongruences are interpreted with reference to a plethora of sociocultural factors including traditional Chinese thinking and institutional expectations. The implications of the findings for stakeholders in universities, including faculty members, students, and curriculum developers in similar contexts, are also discussed. (shrink)

This study examines the mediating role of rumination, state anger, and blame attribution, and the moderating role of trait forgiveness in the relationship between workplace harassment intensity and revenge among employed students at a medium-sized Midwestern U.S. university and full-time employees from various industries in Shanghai, China. We tested the proposed model using techniques described by Hayes. Results within both samples suggested that workplace harassment intensity is positively associated with both major and minor revenge. Results of multiple mediation tests showed (...) that state anger and blame attribution mediated the relationships between workplace harassment intensity and both types of revenge behavior. Furthermore, trait forgiveness moderated the relationship between blame attribution and major revenge. (shrink)

This article reviews the history of international mobility of students from China to other countries over the century and a half from 1870 to the present day. Different motivations, goals, courses, and knowledge are considered, together with how the purposes of individuals have matched national policy. Implications for the future development in a globalized context are briefly considered.

The product market competition has become a global challenge for business organizations in the challenging and competitive market environment in the influx of the COVID-19 outbreak. The influence of products competition on organizational performance in developed economies has gained scholars’ attention, and numerous studies explored its impacts on business profitability. The existing studies designate mixed findings between the linkage of CSR practices and Chinese business firms’ healthier performance in emerging economies; however, the current global crisis due to the coronavirus has (...) made product market completion fierce, which ultimately affects business firms’ performance. This study focuses on this logical global challenge, investigates the rationale, and examines product-market completion impact on firms’ performance operating in the Chinese markets. The study collected data from the annual reports of Chinese business organizations with A-share listing and registered with the database of China Stock Markets and Accounting Research. The study employed a Generalized Method of Moment technique and investigated the connection between product market competition and Chinese firm performance. The empirical analysis of this study highlights the conclusion that market competition positively and significantly affected business firms’ performance. This study specified that product market competition play a dynamic and indispensable role in achieving healthier firm performance in the Chinese markets. This study provides valuable insights on practical implications and future research directions for the scholars to draw interesting results with new study models. (shrink)

In recent years, the analysis of legal judgments and the prediction of outcomes based on case factual descriptions have become hot research topics in the field of judiciary. Among them, the task of charge prediction aims to predict the applicable charges of a judicial case based on its factual description, making it an important research area in the intelligent judiciary. While significant progress has been made in machine learning and deep learning, traditional methods are limited to handling data in Euclidean (...) space and cannot effectively capture the semantic information in the text. To overcome the limitations of traditional learning approaches, many studies have started exploring the use of graphs to represent rich relationships between entities in text and employing graph convolutional neural networks to learn text representations. In this paper, we propose a charge prediction method based on graph convolutional neural networks. By constructing a similarity graph between cases and utilizing graph convolutional neural networks to learn case feature representations, we can better capture the relational information between cases and improve the accuracy of charge prediction. Experimental results on multiple benchmark datasets demonstrate that our proposed model outperforms traditional methods in charge prediction tasks. (shrink)

During late embryonic and early postnatal development, synaptic connections are extensively modified so that some functional connections are weakened and eliminated from a neural circuit while others are strengthened and maintained. The mechanisms that underlie synapse elimination are beginning to be understood from studies of the neuromuscular junction. A recent paper(1) provides some intriguing insights into the role proteases may play in the developmental disassembly of neuromuscular synapses.

Climate change and farming malpractices are harmful to the globe's productive soil and biodiversity, thereby posing a hazard to the survival of future generations. Innovative technologies provide continuous smart conservation solutions, such as regenerative farming, to confront the ongoing climate crisis and maintain biodiversity. Albeit, regenerative farming has the potential to conserve climate change by upgrading the soil's organic materials and reinstating biodiversity leading to carbon attenuation. However, a critical problem remains concerning adapting conservation farming practices that can assist low-income (...) farmers. In this scenario, theoretical-driven communication campaigns are critical for addressing individuals' resistance to innovation. Thereby, this research uncovers the moderating influence of the numerous communication tools in determining the adoption of regenerative farming through diminishing farmers' resistance to innovation. The study employed a cross-sectional design vis-à-vis a survey method. A sample of 863 farmers participated by responding to the self-administrated questionnaire. In line with prior theories, the study's results identified that communication campaigns such as public service advertisements and informative scientific documentaries could reduce the resistance to innovation that increases the attitude toward the adoption of regenerative farming with varied intensity. Besides, informational support also remained a significant contributor in determining the intention to adopt regenerative farming. This specifies that implanting habits of conservation farming requires the initiation of communication campaigns using different media content. These results may be advantageous for policymakers to influence farmers' intentions to adopt regenerative farming. (shrink)

Mental illness stigma is imposed on patients in mental illness stigma mark, mainly referring to the disease and psychological stereotypes lead to the loss of social status and discrimination. Study confirmed the existence of stigma would prevent the patient's treatment and rehabilitation, stigma issues resulting widespread concern in the world health community, which is a hotspot of research on the impact of stigma. Labeling theory and theories of stigma affect the correct label for the analysis of the mechanism; stigma of (...) mental illness and related populations of the various effects can be measured in two ways: public stigma and self-stigma; protest, education and exposure is to reduce the stigma effective way. Chinese culture in the future to carry out the stigma of mental illness, should be closely combined with the stigma of traditional culture analysis of the impact mechanism, and should explore the feasibility of stigma strategies. Mental illness stigma is an ashamed mark attached to people with mental illness, which is the status loss and discrimination triggered by negative stereotypes about people labeled as having mental illness. Some researches have showed that stigma may impede the treating and rehabilitating process of clients. The effect of mental illness stigma is currently a hot subject of research. Labeling theory and modified labeling theory are both the theories of the mechanism of the effect of stigma. Researchers investigate the effects of stigma and the ways of diminishing it from two aspects: public- stigma and self-stigma. The future research orientations in China should be combined with culture analysis. (shrink)

To obtain effective fusion results of multi source evidences with different importance, an evidence fusion method with importance discounting factors based on neutrosopic probability analysis in DSmT framework is proposed. First, the reasonable evidence sources are selected out based on the statistical analysis of the pignistic probability functions of single focal elements. Secondly, the neutrosophic probability analysis is conducted based on the similarities of the pignistic probability functions from the prior evidence knowledge of the reasonable evidence sources. Thirdly, the importance (...) discounting factors of the reasonable evidence sources are obtained based on the neutrosophic probability analysis and the reliability discounting factors of the real-time evidences are calculated based on probabilistic-based distances. Fourthly, the real-time evidences are discounted by the importance discounting factors and then the evidences with the mass assignments of neutrosophic empty sets are discounted by the reliability discounting factors. Finally, DSmT+PCR5 of importance discounted evidences is applied. Experimental examples show that the decision results based on the proposed fusion method are different from the results based on the existed fusion methods. Simulation experiments of recognition fusion are performed and the superiority of proposed method is testified well by the simulation results. (shrink)

As a NP-hard problem that needs to be solved in real time, the dynamic task allocation problem of unmanned aerial vehicle swarm has gradually become a difficulty and hotspot in the current planning field. Aiming at the problems of poor real-time performance and low quality of the solution in the dynamic task allocation of heterogeneous UAV swarm in uncertain environment, this paper establishes a dynamic task allocation model that can meet the actual needs and uses the binary wolf pack algorithm (...) to solve it, so as to propose a dynamic task allocation method of heterogeneous UAV swarm in uncertain environment. In this method, a dynamic mechanism of attacking while searching and priority attacking of important targets is designed. A dynamic task allocation model of multitarget, multitask, heterogeneous multiaircraft platform and multiconstraint is established based on the target cost-effectiveness ratio and task execution time window. In addition, one-dimensional 0–1 coding method is adopted to encode the task allocation scheme. Furthermore, the wolf pack algorithm is introduced in brief. This paper focuses on the BWPA with the good computational robustness and strong global search ability to solve the dynamic allocation model. According to the simulation results, the designed task allocation method not only has good adaptability to the change of target and UAV number, as well as good stability and scalability, but also can effectively solve the dynamic task allocation problem of heterogeneous UAV swarm in unknown environment. Therefore, the established model and solution method can provide a useful reference for task allocation and other related problems. (shrink)

Previous studies on crisis know­ledge organization mostly focused on the categorization of crisis know­ledge without regarding its dynamic trend and temporal-spatial features. In order to emphasize the dynamic factors of crisis collaboration, a fine-grained crisis know­ledge model is proposed by integrating temporal-spatial analysis based on ontology, which is one of the commonly used methods for know­ledge organization. The reconstruction of ontology-based crisis know­ledge will be implemented through three steps: analyzing temporal-spatial features of crisis know­ledge, reconstructing crisis know­ledge ontology, and verifying (...) the temporal-spatial ontology. In the process of ontology reconstruction, the main classes and properties of the domain will be identified by investigating the crisis information resources. Meanwhile the fine-grained crisis ontology will be achieved at the level of characteristic representation of crisis know­ledge including temporal relationship, spatial relationship, and semantic relationship. Finally, we conducted case addition and system implementation to verify our crisis know­ledge model. This ontology-based know­ledge organization method theoretically optimizes the static organizational structure of crisis know­ledge, improving the flexibility of know­ledge organization and efficiency of emergency response. In practice, the proposed fine-grained ontology is supposed to be more in line with the real situation of emergency collaboration and management. Moreover, it will also provide the know­ledge base for decision-making during rescue process. (shrink)

The present text addresses the following questions: Why is the history of ideas in pioneering contemporary Chinese art essentially a history of culture? Why and how is art a kind of historical cultural phenomenon? What kind of challenges will artistic production encounter in the course of China’s civilizational transformation, and which artworks testify to these? These queries constitute the central focus of the history of ideas in pioneering art understood as a history of culture.

This paper presents the philosophical and theological underpinnings of the so-called “world-picture logic” mode of critique. It also outlines the arguments—empirical, transcendental and creationist—upon which the aesthetic framework depends that has the world relational picture as its object. By laying out these arguments and inquiring into the nature of what is human, it sketches the relational theology central to the “world-picture logic” mode of critique.

国家哲学社会科学创新基地浙江大学语言与认知研究中心研究成果中国博士后科学基金资助.

本书介绍曾子的身世背景、曾子的生平、曾子的著作、曾子的思想、曾子与《孝经》的关系、《孝经》的思想内容、《孝经》的影响、历代对曾子的推崇。.

Background The ethical competence of head nurses plays a pivotal role in nursing ethics. Ethical climate is a prerequisite for ethical competence, and moral resilience can positively influence an individual’s ethical competence. However, few studies have focused on the relationship between ethical climate, moral resilience, and ethical competence among them. Objectives To investigate the relationship between ethical climate, moral resilience, and ethical competence, and examine the mediating role of moral resilience between ethical climate and ethical competence among head nurses. Design (...) A quantitative, cross-sectional study. Methods A total of 309 Chinese head nurses completed an online survey, including ethical climate questionnaire, Rushton moral resilience scale, and ethical competence questionnaire. Inferential statistical analysis includes Pearson’s correlation and a structural equation model. Ethical considerations This study received ethical approval from the Institutional Review Board of Xiangya Nursing School of Central South University (No. E2023146). Results Head nurses’ ethical climate score positively impacted ethical competence (r = 0.208, p <.001), and ethical climate could affect ethical competence through the mediating role of moral resilience. Conclusion This study emphasized the value of ethical climate in moral resilience of head nurses, ultimately leading to an enhancement in their ethical competence. (shrink)

One aspect of the intellectual changes taking place in China in the late nineteenth and early twentieth centuries was the emergence of utilitarian ideas. Although it may be useful to think of modern Chinese thought from the perspective of the emergence of social Darwinism and nationalism, it is significant that the country's most progressive scholars at the turn of thecentury derived their inspiration from utilitarianism. Utilitarianism was accepted as a weapon with which to challenge traditional social, political, and cultural ideas, (...) and to justify social and political reforms. (shrink)

PurposeThe primary angle-closure glaucoma is an irreversible blinding eye disease in the world. Previous neuroimaging studies demonstrated that PACG patients were associated with cerebral changes. However, the effect of optic atrophy on local and remote brain functional connectivity in PACG patients remains unknown.Materials and MethodsIn total, 23 patients with PACG and 23 well-matched Health Controls were enrolled in our study and underwent resting-state functional magnetic resonance imaging scanning. The regional homogeneity method and functional connectivity method were used to evaluate the (...) local and remote brain functional connectivity. Moreover, support vector machine method was applied to constructing PACG classification model.ResultsCompared with the HC, PACG patients showed increased ReHo values in right cerebellum _8, left CER_4-5, and right CER_8. In contrast, PACG patients showed decreased ReHo values in the bilateral lingual gyrus /calcarine /superior occipital gyrus and right postcentral gyrus. The ReHo value exhibited an accuracy of 91.30% and area under curve of 0.95 for distinguishing the PACG patients from HC.ConclusionOur study demonstrated that the PACG patients showed abnormal ReHo value in the cerebellum, visual cortex, and supplementary motor area, which might be reflect the neurological mechanisms underlying vision loss and eye pain in PACG patients. Moreover, the ReHo values can be used as a useful biomarker for distinguishing the PACG patients from HCs. (shrink)

Although research on the mismatch negativity (MMN) has been ongoing for 40 years, the generation process of the MMN remains largely unknown. In this study, we used a single-trial EEG-fMRI coupling method which can analyse neural activity with both high temporal and high spatial resolution and thus assess the generation process of the MMN. We elicited the MMN with an auditory oddball paradigm while recording simultaneous EEG and fMRI. We divided the MMN into five equal-durational phases. Utilizing the single-trial variability (...) of the MMN, we analysed the neural generators of the five phases, thereby determining the spatiotemporal generation process of the MMN. We found two distinct bottom-up prediction error propagations: first from the auditory cortex to the motor areas and then from the auditory cortex to the inferior frontal gyrus (IFG). Our results support the regularity-violation hypothesis of MMN generation. (shrink)

本书介绍了经济伦理学的冲撞与整合、历史的探源、利己与利他、自律与他律、公平交易、公平分配等八章内容。.