In the UK, it has been proposed that alongside the current advice to abstain from alcohol completely in pregnancy, there should be increased screening of pregnant women for alcohol consumption in order to prevent instances of fetal alcohol spectrum disorder. The Scottish Intercollegiate Guidelines Network published guidelines in 2019 recommending that standardised screening questionnaires and associated use of biomarkers should be considered to identify alcohol exposure in pregnancy. This was followed in 2020 by the National Institute for Health and Care (...) Excellence Draft Quality Standard, which recommended that pregnant women should have information on their alcohol consumption recorded throughout their pregnancy and this information transferred to the child’s health records. Most recently, Public Health England has stated that the alcohol intake of all women should be recorded throughout pregnancy, not just at the initial booking appointment and that tools such as blood biomarkers and meconium testing should be researched in order to determine true prevalence rates of alcohol in pregnancy. We argue that this proposed enhanced screening undermines women’s autonomy and their legal right to be sufficiently informed to consent to screening. We argue that there is no evidence that this kind of screening will result in a reduction of fetal harm and there is a danger that undermining the autonomy of women and the trust relationship between women and healthcare professionals may even increase harm to future children. (shrink)

Organisations increasingly use digital nudges to influence their workforces’ behaviour without coercion or incentives. This can expose employees to arbitrary domination by infringing on their autonomy through manipulation and indoctrination. Nudges might furthermore give rise to the phenomenon of “organised immaturity.” Adopting a balanced approach between overly optimistic and dystopian standpoints, I propose a framework for determining the moral permissibility of digital nudging in the workplace. In this regard, I argue that not only should organisations provide pre-discursive justification of nudges (...) but they should also ensure that employees can challenge their implementation whenever necessary through legitimation procedures. Building on Rainer Forst’s concept of the right to justification, this article offers a way to combine contract- and deliberation-based theories for addressing questions in business ethics. I further introduce the concept of meta-autonomy as a capacity that employees can acquire to counter threats of arbitrary domination and to mitigate organised immaturity. (shrink)

Games Studies reveals the performative nature of playing a character in a virtual-game-world (Nitsche 2008, p.205; Pearce 2006, p.1; Taylor 2002, p.48). Tbe Player/Character relationship is typically understood in terms of the player’s in-game “presence” (Boellstorff 2008, p.89; Schroeder 2002, p.6). This gives the appearance that living-into a game-world is an all-or- nothing affair: either the player is “present” in the game-world, or they are not. I argue that, in fact, a constitutive phenomenology reveals the Player/Character relationship to be a (...) multi-dimensional matter of empathy. I advance a broadly Schutzian framework, drawing on his 1932 discussions of “face-to-face encounters” and ”historical predecessors,” showing how at- tention to empathy reveals a variety of “presences” that different kinds of Player/Character relationships afford. The central determinants of empathetic affordances which I focus on here are (i) how much players know about a character (especially the character’s past) and (ii) how players learn this information.The purpose of this discussion will be to show that a phenomenological analysis reveals that the relationship between a player and their character is complex, highly variable, and inherently social. Furthermore, it will add to the growing body of scholarship that demonstrates that video games are rich social objects deserving of study. (shrink)

The term “therapeutic misconception” was coined in 1982 by Paul Appelbaum, Loren Roth, and Charles Lidz. Appelbaum and his colleagues interviewed participants in several psychiatric studies, including a drug trial with a placebo control arm. Appelbaum's group found that many people were unaware of the differences between participating in a study and receiving treatment in the clinical setting. Rather than understanding these differences, study participants tended to believe that therapy and research were governed by the same primary goal: to advance (...) the individual patient's best interests. Appelbaum's group labeled this mistaken belief the therapeutic misconception. (shrink)

Many people are worried about developing dementia, fearing the losses and burdens that accompany the condition. Dementia‐specific advance directives are intended to address dementia's progressive effects, allowing individuals to express their treatment preferences for different stages of the condition. But enthusiasm for dementia‐specific advance directives should be tempered by recognition of the legal, ethical, and practical issues they raise. Dementia‐specific advance directives are a simplistic response to a complicated situation. Although they enable people to register their future care preferences, in (...) many cases, those preferences will not, and should not, determine their later care. (shrink)

We can safely infer that a proposition is possible if p is the case. But, I argue, this inference from the actual to the possible is merely explicative in nature, though we employ it at times as if it were ampliative. To make this inference ampliative, we need to include an inference to the best explanation. Specifically, we can draw a substantive conclusion as to whether p is possible from the fact that p is the case, if via our best (...) explanation we can explain how p could occur again in the complete and coherent set of propositions that describes the actual world. (shrink)

: Some critics find that Thomas Reid thinks the mind especially problematic, "hid in impenetrable darkness". I disagree. Reid does not hold that mind, more than body, resists explanation by the new science. The physical sciences have made great progress because they were transformed by the Newtonian revolution, and the key transformation was to stop looking for causes. Reid's harsh words are a call for methodological reform, consonant with his lifelong pursuit of a science of mind and also with his (...) frequent (though overlooked) optimism about such a science. (shrink)

This chapter discusses eighteenth-century British theories of perception, beginning with George Berkeley’s Essay Towards a New Theory of Vision. The chapter traces Berkeley’s influence through Thomas Reid, David Hume, David Hartley, Adam Smith and Dugald Stewart. The chapter presents theories of perception in this time a place a primarily concerned with metaphysics, mind and methodology rather than epistemology.

Some research is too risky to be conducted on anyone whose life expectancy is more than a few hours. Yet sometimes, the research can still be carried out using subjects who are brain dead or are soon to undergo a terminal wean, and who have articulated values that inclusion in the study can honor. So argues a team of ethicists and researchers at M.D. Anderson Cancer Center, where such research was recently undertaken.

The important roles of prediction and prior experience are well established in music research and fit well with Clark's concept of unified perception, cognition, and action arising from hierarchical, bidirectional predictive processing. However, in order to fully account for human musical intelligence, Clark needs to further consider the powerful and variable role of affect in relation to prediction error.

The American Journal of Bioethics, Volume 12, Issue 1, Page 16-18, January 2012.

I welcome the efforts described by Neal Dickert and his colleagues in “Partnering with Patients to Bridge Gaps in Consent for Acute Care Research” (Dickert et al. 2020). I am a long-time supporter...

It's not unusual to hear someone say, ‘I'd rather be dead than have Alzheimer's’. In ‘Alzheimer Disease and Preemptive Suicide’,1 Dena Davis explains why this is a reasonable position. People taking this position will welcome the discovery of biomarkers permitting very early AD diagnosis, Davis suggests, for this will enable more of them to end their lives while they remain motivated and able to do so. At the same time, Davis observes, people would have less reason to resort to the (...) drastic remedy of pre-emptive suicide if they had absolute authority over the medical treatment they received as patients with dementia; but the threat of pre-emptive suicide is not, in my view, a sufficient reason to grant competent individuals that authority.If preclinical diagnosis of AD becomes possible, some pre-emptive suicides will probably occur. There would be no ethical or practical way to ban such suicides, and it would be silly to try. Clinicians will undoubtedly try to discourage people seeking biomarker information in furtherance of a suicide plan, but savvy individuals will simply conceal their true motivation for having the tests. The real problem for people intent on self-destruction is that biomarkers are unlikely to deliver a clear suicide signal.First, as Davis notes, work on biomarkers remains in the research stage. No one yet knows whether biomarker tests will prove accurate enough to warrant clinical use. Second, even clinically accepted biomarker tests will generate imperfect information about future disease. Biomarkers may produce more accurate estimates of a person's risk of developing AD, but like all predictive tests, they will also yield false positive and negative results. The …. (shrink)

Some interpret Reid’s notion of a moral sense as merely analogical. Others understand it as a species of acquired perception. To understand Reid’s account of the moral sense, we must draw from his theory of perception and his theory of aesthetic experience, each of which illuminate the nature and operation of the moral faculty. I argue that, on Reid’s view, the moral faculty is neither affective nor rational, but representational. It is a discrete, basic, capacity for representing the real moral (...) properties of humans and human conduct. (shrink)

This paper presents an overview of the dimensions of unsafe motherhood, contrasting data from economically developed countries with some from developing countries. It addresses many common factors that shape unsafe motherhood, identifying medical, health system and societal causes, including women's powerlessness over their reproductive lives in particular as a feature of their dependent status in general. Drawing on perceptions of Jonathan Mann, it focuses on public health dimensions of maternity risks, and equates the role of bioethics in conscientious medical care (...) to that of human rights in public health care. The microethics of medical care translate into the macroethics of public health, but the transition compels some compromise of personal autonomy, a key feature of Western bioethics, in favour of societal analysis. Religiously‐based morality is seen to have shaped laws that contribute to unsafe motherhood. Now reformed in former colonizing countries of Europe, many such laws remain in effect in countries that emerged from colonial domination. UN conferences have defined the concept of ‘reproductive health’ as one that supports women's reproductive self‐determination, but restrictive abortion laws and practices epitomize the unjust constraints to which many women remain subject, resulting in their unsafe motherhood. Pregnant women can be legally compelled to give the resources of their bodies to the support of others, while fathers are not legally compellable to provide, for instance, bone‐marrow or blood donations for their children's survival. Women's unjust legal, political, economic and social powerlessness explains much unsafe motherhood and maternal mortality and morbidity. (shrink)

In this essay, I explore alternatives to traditional philosophical writing assignments. I propose that inviting students to engage with philosophical ideas creatively can make our writing instruction more inclusive. Creative assignments, I argue, can achieve the same goals as traditional writing assignments but are able to sidestep some of the assumptions and habits that make it harder for students to experience writing as an authentic act of self-expression. I also discuss assessment strategies and provide several sample assignments including grading criteria.

Henri Bergson's philosophy presents the relationship between life and matter in both dualistic and monistic terms. Life is duration, a rhythm of incalculable novelty that approaches pure creative activity. In stark contrast, matter is identified with the determinism of homogeneous space. After Time and Free Will, Bergson concedes some share of duration to matter. In this context, his dualism can be understood as a methodological step towards the articulation of a monistic metaphysics of duration. This article suggests that the distinction (...) between life and matter is also motivated by an unconscious imperative to establish a sexed hierarchy. Bergson repeatedly presents life as seminal, while matter is figured in terms of passivity. (shrink)

Qualitative longitudinal research (QLR) provides temporal understanding of the human response to health, illness, and the life course. However, little guidance is available for conducting QLR in the nursing literature. The purpose of this review is to describe the methodological status of QLR in nursing. With the assistance of a medical librarian, we conducted a thorough search circumscribed to qualitative, longitudinal nursing studies of patients’ and care‐givers’ experiences published between 2006 and 2016. The methodological quality of the 74 reviewed studies (...) varied tremendously; many reports lacked sufficient detail in reporting on sampling and attrition, retention strategies, and data collection and analysis, making it difficult for readers to evaluate the credibility and transferability of study findings. Based on the strengths and limitations of the studies reviewed and findings in the literature, we provide recommendations for enhancing the reporting of the research process as a supplement to the standards for qualitative research more broadly. These recommendations are offered in the spirit of encouraging dialogue among colleagues and assisting journal reviewers and editors in their evaluation of QLR. (shrink)

During the oppressive reign of Louis XIV, Gabrielle Suchon was the most forceful female voice in France, advocating women’s freedom and self-determination, access to knowledge, and assertion of authority. This volume collects Suchon’s writing from two works—_Treatise on Ethics and Politics_ and _On the Celibate Life Freely Chosen; or, Life without Commitments _—and demonstrates her to be an original philosophical and moral thinker and writer. Suchon argues that both women and men have inherently similar intellectual, corporeal, and spiritual capacities, which (...) entitle them equally to essentially human prerogatives, and she displays her breadth of knowledge as she harnesses evidence from biblical, classical, patristic, and contemporary secular sources to bolster her claim. Forgotten over the centuries, these writings have been gaining increasing attention from feminist historians, students of philosophy, and scholars of seventeenth-century French literature and culture. This translation, from Domna C. Stanton and Rebecca M. Wilkin, marks the first time these works will appear in English. (shrink)

ArgumentThe Minnesota Multiphasic Personality Inventory (MMPI) was developed at the University of Minnesota, Minneapolis, in the 1930s and 1940s. It became a highly successful and highly controversial psychometric tool. In professional terms, psychometric tools such as the MMPI transformed psychology and psychiatry. Psychometric instruments thus readily fit into the developmental history of psychology, psychiatry, and neurology; they were a significant part of the narrative of those fields’ advances in understanding, intervening, and treating people with mental illnesses. At the same time, (...) the advent of such tools also fits into a history of those disciplines that records the rise of obsessional observational and evaluative techniques and technologies in order to facilitate patterns of social control that became typical during the Progressive Era in the United States and after. It was those patterns that also nurtured the resistance to psychometrics that emerged during the Vietnam War and after. (shrink)

A general framework by which dynamic interactions within a protein will promote the necessary series of structural changes, or “conformational cycle,” required for function is proposed. It is suggested that the free‐energy landscape of a protein is biased toward this conformational cycle. Fluctuations into higher energy, although thermally accessible, conformations drive the conformational cycle forward. The amino acid interaction network is defined as those intraprotein interactions that contribute most to the free‐energy landscape. Some network connections are consistent in every structural (...) state, while others periodically change their interaction strength according to the conformational cycle. It is reviewed here that structural transitions change these periodic network connections, which then predisposes the protein toward the next set of network changes, and hence the next structural change. These concepts are illustrated by recent work on tryptophan synthase. Disruption of these dynamic connections may lead to aberrant protein function and disease states. (shrink)

Parental age at offspring conception often influences offspring longevity, but the mechanisms underlying this link are poorly understood. One mechanism that may be important is telomeres, highly conserved, repetitive sections of non‐coding DNA that form protective caps at chromosome ends and are often positively associated with longevity. Here, the potential pathways by which the age of the parents at the time of conception may impact offspring telomeres are described first, including direct effects on parental gamete telomeres and indirect effects on (...) offspring telomere loss during pre‐ or post‐natal development. Then a surge of recent studies demonstrating the effects of parental age on offspring telomeres in diverse taxa are reviewed. In doing so, important areas for future research and experimental approaches that will enhance the understanding of how and when these effects likely occur are highlighted. It is concluded by considering the potential evolutionary consequences of parental age on offspring telomeres. (shrink)

In Tough Choices for Teachers: Ethical Challenges in Today's Schools and Classrooms, Infantino and Wilke help student teachers, new teachers, and experienced teachers think more deeply about ethical concerns. The case studies included by the authors involve ethical dilemmas dealing with honesty, integrity, and proper professional behavior.

Ethics & Behavior, Volume 21, Issue 5, Page 431-434, September-October 2011.

Der Artikel untersucht den originären Beitrag Simon Kronbergs zur deutschen Literatur des Expressionismus. Der zu den „vergessenen und verkannten Autoren der expressionistischen Generation” (Lützeler) gehörende Kronberg ist bis heute kaum untersucht. Als Sohn jüdisch-galizischer Zuwanderer 1891 in Wien geboren, studiert er 1913 bei Emile Jacques-Dalcroze, dessen Licht- und Bewegungschoreographien ihn nachhaltig prägen. Weitere Stationen sind Düsseldorf bei dem Schauspieler-Paar Lindemann/dumont, München und Berlin. 1934 emigriert er nach Palästina, wo er 1947 stirbt. Seine Texte entwerfen eine Sprache, deren sinnstiftende Bilder von (...) seiner biographischen Erfahrung geprägt sind und jüdische Mystik, Tanz und Rhythmus auf spezifische Weise integrieren. Im Zentrum steht Kronbergs Konzeption des Schattens als einer Möglichkeit der Wandlung des Menschen in einer Welt der Rationalität und der Entkopplung des täglichen Lebens von Körper und Sinnlichkeit hin zu einer Erfahrung des Lichts. Am Beispiel seiner Erzählung “Chamlam” zeigt der Beitrag, dass seine Schattenfiguren in einem beachtenswerten Spannungsverhältnis zum Diskurs der Gespenster im Expressionismus stehen. (shrink)

Ch. G. Bardili (1761-1808) ist der Begrunder des rationalen Realismus mit dem Ziel eines von der Materialitat ausgehenden Gottesbeweises. Heute nur noch als von den Zeitgenossen fast einhellig abgelehnter Denker bekannt, bietet sein Schaffen in der enormen Spannbreite von Wissenschaftsreflexionen, Ethik, Philosophiegeschichte und Logik doch ein interessantes, facettenreiches und in seiner Radikalitat anregendes Gesamtkonzept. Dieses Werk erstmals in vollem Umfang zu erschliessen, das ganze System Bardilis in seiner Entwicklung und seinen Inhalten nachzuzeichnen sowie in seinen Grundzugen, die fur die Debatten (...) der Zeit, etwa mit Fichte, Schelling und Reinhold, bedeutsam sind, aufzuweisen, ist die Absicht des vorliegenden Bandes.'Bislang liegt uber Bardili keine nennenswerte Literatur vor. [.] Diese Lucke schliesst nun die vorgelegte Monographie, [.] um so ein Werk vorzustellen, das zwar heute weitgehend in den Hintergrund geruckt oder oft schlicht vergessen ist, das es gleichwohl - wie die Vf. uberzeugend zu zeigen vermag - verdient hat, wieder starkere Beachtung zu finden, weil es zu zentralen Fragestellungen, wie sie im Bereich der klassischen deutschen Philosophie wichtig und bestimmend geworden sind, eine haufig zweifellos eigenwillige, aber trotzdem wegen seines hohen Grades an Originalitat und seiner radikalen, wenn auch bisweilen exzentrisch anmutenden, Alternativstellung bedenkenswerte Anstosse bietet. [.] Insgesamt leistet die Vf. mit ihrer Monographie Hervorragendes und Vorbildliches: Sie zeichnet den Denkweg und das System Bardilis in ihrer Entwicklung und ihren Inhalten nach. Die wesentlichen Grundzuge, die sich fur die Debatten, Streitgesprache und [.] philosophischen Konstellationen der Zeit als so bedeutsam erwiesen, werden pragnant aufgewiesen und mit denkerisch hochster Souveranitat durchdrungen.' Dirk Cursgen, Philosophische Rundschau. (shrink)

Levonorgestrel is widely used as emergency contraception, yet much confusion surrounds its use. Consensus statements and reviews typically attribute its efficacy to prefertilization mechanisms of action, such as suppression of ovulation and interference with cervical mucus or sperm function, yet studies do not rule out a postovulatory MOA. To yield greater clarity, the authors review recent scientific studies examining the MOAs of LNG-EC. They conclude that LNG-EC exerts minimal effects on cervical mucus and sperm function and that suppression of ovulation (...) is not the dominant MOA accounting for the contraceptive efficacy of LNG-EC. Luteal deficiencies and endometrial changes reported in the literature strongly suggest a postovulatory MOA when LNG-EC is given during the critical preovulatory period. National Catholic Bioethics Quarterly 13.4 : 677–716. (shrink)

Body Worlds is a hugely popular exhibition that claims to offer a reverential and educational experience of the ‘real human body’ through the display of plastinated dead human bodies. However, because they are posed, staged, and composed of significant nonhuman artifice, plastinates are ambivalently ‘real’ as human bodies, let alone ‘real’ as humans. Plastinates are as much nonhuman as human, and neither category fully accounts for them. In this article, I discuss the consequences of this for feminist theory. Approaches in (...) feminist theory that reify, either implicitly or explicitly, a human/nonhuman binary framework are challenged by plastinates. I show that locating plastinates within either ontological category, though not fully accounting for them, enables feminist critiques of the exhibition; however, these categories also paradoxically permit forms of violence with which feminists are typically concerned. In this way, I argue that plastinates force feminist thought to the very interface of the human/nonhuman divide. When applied to Body Worlds, these concepts at best form a heuristic ontological hinge whose angle is determined by ethical and political commitments, illustrating the ways in which key ontologies should be seen as political strategies more or less amenable to feminist goals, but not more or less true. I argue that what lies at the crux of this hinge, in the case of plastinates, is death, and suggest that Body Worlds demands that the interface of death with life become a key feminist concern. (shrink)

Can films philosophize rather than simply represent philosophical ideas developed outside of the cinematic medium? Taking up this question crucial to the emergent field of film philosophy, this book argues that the films of the American avant-garde do "do" philosophy and illuminates the ethical and political stakes of their aesthetic interventions. The book traces the avant-garde's philosophy by developing a history and theory of its investment in dimensional, conceptual, and material in-betweens, clarifying how this cinema's reflections on the creation and (...) reception of images construct an ethics of perception itself, a responsibility to perpetuate thought in an enduring re-encounter with the world and with meaning's unfinished production. This entails the avant-garde's locating of cinema's-and thought's-ends or meanings in their means, and their advancement of an image of truth that is made rather than found that unites their films with the philosophies of Ludwig Wittgenstein and Ralph Waldo Emerson who believed the "journey's end is found in every step of the road" (Cavell). Rectifying film-philosophy's neglect of the American avant-garde, the book demonstrates how rather than showing their interest in the revelation of authoritative truths, the avant-garde's interest in the re-encounter and review of the seen and known emerges from an American Transcendentalist tradition that opposes such notions. Sheehan reads the avant-garde's interest in the contingencies of spectatorial experience as also an extension of Pragmatism's commitment to replacing the authority of a priori knowledge with that of individual experience. She also shows how Emerson's influence on Friedrich Nietzsche connects the American avant-garde's philosophies to Deleuze's time-image, premised largely upon Nietzsche's "powers of the false.". (shrink)

In 1997, when Oregon became the first U.S. jurisdiction authorizing medical aid in dying (MAID), its law included a requirement that patients be legal residents of the state. Other U.S. jurisdictions legalizing MAID followed Oregon in adopting residency requirements. Recent litigation challenges the legality, as well as the justification, for such requirements. Facing such challenges, Oregon and Vermont eliminated their MAID residency requirements. More states could follow this move, for, in certain circumstances, the U.S. Constitution's privileges and immunities clause protects (...) citizens’ right to travel to secure medical care. Policy considerations could also motivate states to reexamine whether such requirements are justified in light of existing evidence of how MAID laws have been applied. (shrink)

The term “off-label drug use” refers to drugs that have not yet acquired “approved” status or drugs that have acquired “approved” status but are used with a different dosage, route, or administration method other than that for which the drug has been approved. In New Zealand, the Medicines Act 1981 specifically allows for off-label drug use. However, this authority is limited by the Health and Disability Commissioner Regulations 1996 and the common law, which require that off-label drug use is of (...) an acceptable standard, that the patient should be fully informed, and that the patient should give informed consent. Off-label drug use is an important issue because the current law provides medical practitioners very wide discretionary power, without providing clarification for what is required of the practitioner in exercising his or her discretion in prescribing off-label. This paper discusses possible solutions to this issue, for example, establishing protocol for off-label use, an electronic database of off-label use, and the amendment of legal provisions. (shrink)