Microbial ecology is flourishing, and in the process, is making contributions to how the ecology and biology of large organisms is understood. Ongoing advances in sequencing technology and computational methods have enabled the collection and analysis of vast amounts of molecular data from diverse biological communities. While early studies focused on cataloguing microbial biodiversity in environments ranging from simple marine ecosystems to complex soil ecologies, more recent research is concerned with community functions and their dynamics over time. Models and concepts (...) from traditional ecology have been used to generate new insight into microbial communities, and novel system-level models developed to explain and predict microbial interactions. The process of moving from molecular inventories to functional understanding is complex and challenging, and never more so than when many thousands of dynamic interactions are the phenomena of interest. We outline the process of how epistemic transitions are made from producing catalogues of molecules to achieving functional and predictive insight, and show how those insights not only revolutionize what is known about biological systems but also about how to do biology itself. Examples will be drawn primarily from analyses of different human microbiota, which are the microbial consortia found in and on areas of the human body, and their associated microbiomes (the genes of those communities). Molecular knowledge of these microbiomes is transforming microbiological knowledge, as well as broader aspects of human biology, health and disease. (shrink)

Biomedical Ontologies integrate diverse biomedical data and enable intelligent data-mining and help translate basic research into useful clinical knowledge. We present the RNA Ontology (RNAO), an o...

We report on our experiences in a participatory design project to develop ICTs in a hospital ward working with deliberate self-harm patients. This project involves the creation and constant re-creation of socio-technical ensembles that satisfy the various, changing and often contradictory and conflicting needs in this context. Such systems are shaped in locally meaningful ways but nevertheless reach beyond their immediate context to gain wider importance and to be integrated with the larger environment.

Ever since they began to take an interest in lens grinding, the brothers Christiaan and Constantijn Huygens searched for high-quality glass to turn in to lenses. Historical research in combination with optical measurements on preserved lenses has allowed the verificationof the lenses ground by the brothers, and also provided information on who helped them with the necessary knowledge and material.

The value of accuracy and quantity as memory measures is assessed. It is argued that (1) accuracy does not measure correspondence (monitoring) because it ignores omissions and correct rejections, (2) quantity is confounded with monitoring in recall, and (3) in recognition, if targets and foils are unequal, both measures, even together, still ignore correct rejections.

The troubling ethics and politics of philanthropy Is philanthropy, by its very nature, a threat to today’s democracy? Though we may laud wealthy individuals who give away their money for society’s benefit, Just Giving shows how such generosity not only isn’t the unassailable good we think it to be but might also undermine democratic values and set back aspirations of justice. Big philanthropy is often an exercise of power, the conversion of private assets into public influence. And it is a (...) form of power that is largely unaccountable, often perpetual, and lavishly tax-advantaged. The affluent—and their foundations—reap vast benefits even as they influence policy without accountability. And small philanthropy, or ordinary charitable giving, can be problematic as well. Charity, it turns out, does surprisingly little to provide for those in need and sometimes worsens inequality. These outcomes are shaped by the policies that define and structure philanthropy. When, how much, and to whom people give is influenced by laws governing everything from the creation of foundations and nonprofits to generous tax exemptions for donations of money and property. Rob Reich asks: What attitude and what policies should democracies have concerning individuals who give money away for public purposes? Philanthropy currently fails democracy in many ways, but Reich argues that it can be redeemed. Differentiating between individual philanthropy and private foundations, the aims of mass giving should be the decentralization of power in the production of public goods, such as the arts, education, and science. For foundations, the goal should be what Reich terms “discovery,” or long-time-horizon innovations that enhance democratic experimentalism. Philanthropy, when properly structured, can play a crucial role in supporting a strong liberal democracy. Just Giving investigates the ethical and political dimensions of philanthropy and considers how giving might better support democratic values and promote justice. (shrink)

Andre Breton discusses the meaning, aims, and political position of the Surrealist movement.

Competitive Governments, explores in a systematic way the hypothesis that governments are internally competitive, that they are competitive in their relations with each other and in their relations with other institutions in society which, like them, supply consuming households with goods and services. Breton contends that competition not only serves to bring the political system to an equilibrium, but it also leads to a revelation of the households' true demand functions for publicly provided goods and services and to the (...) molding of a link between the quantities and the qualities demanded and supplied and the tax prices paid for these goods and services. In the real world where information is costly, the links may not be first-best, but they will be efficient if competition is vigorous. (shrink)

A short analysis, by 'one-who-was-there,' of one of the most significant art movements of our century.

To date, research examining the socio-spatial effects of smart city technologies have charted how they are reconfiguring the production of space, spatiality and mobility, and how urban space is governed, but have paid little attention to how the temporality of cities is being reshaped by systems and infrastructure that capture, process and act on real-time data. In this article, we map out the ways in which city-scale Internet of Things infrastructures, and their associated networks of sensors, meters, transponders, actuators and (...) algorithms, are used to measure, monitor and regulate the polymorphic temporal rhythms of urban life. Drawing on Lefebvre, and subsequent research, we employ rhythmanalysis in conjunction with Miyazaki’s notion of ‘algorhythm’ and nascent work on algorithmic governance, to develop a concept of ‘algorhythmic governance’. We then use this framing to make sense of two empirical case studies: a traffic management system and sound monitoring and modelling. Our analysis reveals: how smart city technologies computationally perform rhythmanalysis and undertake rhythm-making that intervenes in space-time processes; distinct forms of algorhythmic governance, varying on the basis of adaptiveness, immediacy of action, and whether humans are in-, on-, or, off-the-loop; and a number of factors that shape how algorhythmic governance works in practice. (shrink)

We develop a model of ideals-based accountability which we have witnessed at work in several long-thriving family businesses. The owners and managers of these firms eschew individualism and materiality in the pursuit of ethical ideals such as supporting democracy and bettering the human condition. Although accountability is to these ideals, not for outcomes such as profitability or even reputation, IBA has resulted in outstanding reputations for some firms. We characterize IBA according to its missions, leadership, culture, and stakeholder relationships. We (...) also contrast it with traditional forms of accountability and differentiate IBA from related stakeholder, stewardship, and CSR perspectives. Finally, we examine its manifestations within five long-lived family enterprises, in the process generating propositions to advance the concept. (shrink)

This article proposes a new reading of transformative learning theory (TAT), proceeding from an examination of three concepts: the function of habit in the processes of constructing experience, the notion of trial and its potential, and the biographical dimensions of Transformative Learning Theory. This approach leads us to question the theories of experience that tacitly underlie the learning models proposed by Mezirow. The discussion thus opened is part of the controversy and dialogue between the currents of pragmatism, critical hermeneutics and (...) biographical research. (shrink)

In his recent article On Relativity Theory and Openness of the Future (1991), Howard Stein proves not only that one can define an objective becoming relation in Minkowski spacetime, but that there is only one possible definition available if one accepts certain natural assumptions about what it is for becoming to occur and for it to be objective. Stein uses the definition supplied by his proof to refute an argument due to Rietdijk (1966, 1976), Putnam (1967) and Maxwell (1985, 1988) (...) that Minkowski spacetime leaves no room for objective becoming whatsoever. However, Stein's proof does not seem to go far enough. By considering only what events have become from the standpoint of any given event, Stein's uniqueness proof fails from the outset to allow for a more general kind of becoming whereby it is understood to occur from the standpoint of events on the particular worldlines followed by observers. This suggests that there may, after all, be more than one way to define objective becoming in Minkowski spacetime once each observer's worldline is allowed to figure in the definition. This suspicion is further aroused by two recent proposals for objective, worldline-dependent becoming due to Peacock (1992) and Muller (1992) who advocate ways of defining becoming that are not equivalent to the definition Stein's uniqueness proof delivers. Nevertheless, we show that Stein's uniqueness proofcan be extended in a natural way to cover this more general kind of becoming, provided one does not enrich standard Minkowski spacetime by privileging certain sets of worldlines over others in an unwarranted manner. Thus we aim to reinforce Stein's point that standard Minkowski spacetime does make room for objective becoming, but in essentially only one way, despite arguments and proposals to the contrary. (shrink)

"La méditation du Principe est le principe même de la philosophie." Cette sentence par laquelle débute le présent ouvrage ne décline pas seulement le projet d'un livre, elle traduit l'ambition d'une oeuvre. Son auteur, Stanislas Breton, disparu le 2 avril 2005, métaphysicien original et génial, parvenu alors au faîte d'une recherche initiée dans les universités romaines, poursuivie dans les Instituts catholiques de Lyon de Paris et relancée à l'Ecole normale supérieure d'Ulm, en déroulait alors la thèse dans une étonnante (...) fulgurance. Trente ans exactement après sa première publication, celle-ci se trouve à nouveau, plus actuelle que jamais, présentée au public. Les quatre parties qui la structurent sont consacrées au concept antique de "Principe" à "l'Ineffable" auquel il se trouve nécessairement confronté, à ses usages en philosophie et en théologie, et à la critique à laquelle le soumet la pensée contemporaine. Elles déchiffrent, chemin faisant, ce qui décide, sous des modes bien différents, de l'"organisation du pensable" à l'intérieur des philosophies et des théologies. Ainsi réédité, cet ouvrage se livre à l'inspiration de nouvelles générations soucieuses d'honorer et d'exploiter, dans la ligne du N Fonds Breton une oeuvre d'exception. (shrink)

Creativity: Theory, History, Practice offers important new perspectives on creativity in the light of contemporary critical theory and cultural history. Innovative in approach as well as argument, the book crosses disciplinary boundaries and builds new bridges between the critical and the creative. It is organized in four parts: · Why creativity now? offers much-needed alternatives to both the Romantic stereotype of the creator as individual genius and the tendency of the modern creative industries to treat everything as a commodity. · (...) Defining creativity, creating definitions traces the changing meaning of "create" from religious ideas of divine creation from nothing to advertising notions of concept creation. It also examines the complex history and extraordinary versatility of terms such as imagination, invention, inspiration and originality. · Creation as myth, story, metaphor begins with modern re-telling of early African, American and Australian creation myths and -picking up Biblical and evolutionary accounts along the way - works round to scientific visions of the Big Bang, bubble universes and cosmic soup. · Creative practices, cultural processes is a critical anthology of materials, chosen to promote fresh thinking about everything from changing constructions of "literature" and "design" to artificial intelligence and genetic engineering. Rob Pope takes significant steps forward in the process of rethinking a vexed yet vital concept, all the while encouraging and equipping readers to continue the process in their own creative or "re-creative" ways. Creativity: Theory, History, Practice is invaluable for anyone with a live interest in exploring what creativity has been, is currently, and yet may be. (shrink)

Many amateur sportsmen in the West, have today started undertaking long and intensive ordeals where their personal capacity to withstand increasing suffering is the prime objective. Running, jogging, the triathlon and trekking are the sorts of ordeal where people without any particular ability are not pitting themselves against others but are committed to testing their own capacity to withstand increasing pain. Constantly called upon to prove themselves in a society where reference points are both countless and contradictory and where values (...) are in crisis, people are now seeking a one-to-one relationship by redical means, testing their strength of character, their courage and their personal resources. Going right on to the end of a self-imposed ordeal gives a legitimacy to life and provides a symbolic plank that supports them. Performance itself is of secondary significance; it has a value only to the individual. There is no struggle against a third party, only a method for reinforcing personal will-power and over-coming suffering by going right to the limit of a personally imposed demand. The physical limit has come to replace the moral limit that present-day society is failing to provide. Overcoming suffering tempers the individual, providing a renewed significance and value to his life. (shrink)

In an increasingly complex world with increasingly powerful organisations it seems inevitable that society – or groups in society – would become anxious about whether these organisations could be encouraged to match that power with an appropriate responsibility. This is the function of accountability – to require individuals and organisations to present an account of those actions for which society holds them – or would wish to hold them – responsible. And the history of social accounting, at its most fundamental, (...) is a history of attempts to develop this accountability. It seems to me that the widespread and systematic practice of social and environmental accounting is a deeply essential element in any well‐functioning, complex democracy. The corollary is that the absence of such mechanisms raises fundamental questions about the nature of modern democracies. This article briefly outlines what I believe to be the three strands of social accounting. It then identifies a few of the lessons that we may be able to learn from current experience and, in particular, how social accounting is related to accountability, democracy and sustainability. The central issue of the tension between accountability and control is touched upon: I then illustrate how the stakeholder model can be used to help define the social account, and conclude with a few words on attestation. (shrink)

_Yanomami_ raises questions central to the field of anthropology—questions concerning the practice of fieldwork, the production of knowledge, and anthropology's intellectual and ethical vision of itself. Using the Yanomami controversy—one of anthropology's most famous and explosive imbroglios—as its starting point, this book draws readers into not only reflecting on but refashioning the very heart and soul of the discipline. It is both the most up-to-date and thorough public discussion of the Yanomami controversy available and an innovative and searching assessment of (...) the current state of anthropology. The Yanomami controversy came to public attention through the publication of Patrick Tierney's best-selling book, _Darkness in El Dorado,_ in which he accuses James Neel, a prominent geneticist who belonged to the National Academy of Sciences, as well as Napoleon Chagnon, whose introductory text on the Yanomami is perhaps the best-selling anthropological monograph of all time, of serious human rights violations. This book identifies the ethical dilemmas of the controversy and raises deeper, structural questions about the discipline. A portion of the book is devoted to a unique roundtable in which important scholars on different sides of the issues debate back and forth with each other. This format draws readers into deciding, for themselves, where they stand on the controversy’s—and many of anthropology’s—central concerns. All of the royalties from this book will be donated to helping the Yanomami improve their healthcare. (shrink)

ABSTRACT In this paper I explore the role of imagination in ethical life. I do so by discussing the thought of Kierkegaard and Murdoch, both of whom stress the importance as well as the dangerousness of imagination for ethical life. Both distinguish between proper imagination and mere fantasy in dealing with the tension. Anti-Climacus’s views on imagination emphasize that the proper use of the imagination plays a vital role in realizing the fundamental ethical task of becoming ourselves, whereas fantasy only (...) alienates us from ourselves. Murdoch’s account of imagination stresses that a proper use of the imagination contributes to the realization of a selfless attunement to the world, whereas fantasy only reinforces the (what she describes as) ‘fat, relentless ego’. In the final part of the paper I discuss some existing comparisons between both accounts. I conclude by drawing attention to the fundamental choice that comparing their views on the role of imagination in ethical life confronts us with: should we be existentialists or mystics in ethics? (shrink)

Rob Clifton was one of the most brilliant and productive researchers in the foundations and philosophy of quantum theory, who died tragically at the age of 38. Jeremy Butterfield and Hans Halvorson collect fourteen of his finest papers here, drawn from the latter part of his career (1995-2002), all of which combine exciting philosophical discussion with rigorous mathematical results. Many of these papers break wholly new ground, either conceptually or technically. Others resolve a vague controversy intoa precise technical problem, which (...) is then solved; still others solve an open problem that had been in the air for soem time. All of them show scientific and philosophical creativity of a high order, genuinely among the very best work in the field. The papers are grouped into four Parts. First come four papers about the modal interpretation of quantum mechanics. Part II comprises three papers on the foundations of algebraic quantum field theory, with an emphasis on entanglement and nonlocality. The two papers in Part III concern the concept of a particle in relativistic quantum theories. One paper analyses localization; the other analyses the Unruh effect (Rindler quanta) using the algebraic approach to quantum theory. Finally, Part IV contains striking new results about such central issues as complementarity, Bohr's reply to the EPR argument, and no hidden variables theorems; and ends with a philosophical survey of the field of quantum information. The volume includes a full bibliography of Clifton's publications. Quantum Entanglements offers inspiration and substantial reward to graduates and professionals in the foundations of physics, with a background in philosophy, physics, or mathematics. (shrink)

Entanglement has long been the subject of discussion by philosophers of quantum theory, and has recently come to play an essential role for physicists in their development of quantum information theory. In this paper we show how the formalism of algebraic quantum field theory (AQFT) provides a rigorous framework within which to analyse entanglement in the context of a fully relativistic formulation of quantum theory. What emerges from the analysis are new practical and theoretical limitations on an experimenter's ability to (...) perform operations on a field in one spacetime region that can disentangle its state from the state of the field in other spacelike-separated regions. These limitations show just how deeply entrenched entanglement is in relativistic quantum field theory, and yield a fresh perspective on the ways in which the theory differs conceptually from both standard non-relativistic quantum theory and classical relativistic field theory. (shrink)

This article discusses studies and politicalinitiatives concerned with enhancing publicinvolvement in major technological decisions.It argues that such decisions should include asignificant role for the mass media, andrespect for the diverse relations betweenscience and governance. The notion of`regulated worlds' is proposed as a startingpoint in a discourse that brings together themass media, science management, anddeliberative democracy.

This article offers a semiotic perspective on the debate over critical race theory (CRT) bans in the United States. It presents the debate as unfolding in three stages. In the first stage, CRT is created by an opportunistic journalist as a catchall category for white grievances, and the bans themselves are seen as consistent with freedom of speech, and Martin Luther King Jr.’s vision of a colorblind society. A semiotic rupture, occasioned by Timothy Snyder’s 2021, _New York Times Magazine_ article (...) “The War on History is a War on Democracy,” ushered in a second stage. By comparing CRT bans to Vladimir Putin’s use of law to deny Soviet past crimes (especially regarding Ukraine), Snyder exposed the CRT bans as willful acts of forgetting past crimes, while indirectly highlighting Putin’s own anti-woke initiatives. This led to the third stage, in which some CRT ban supporters began to view critical race theory as form of communism. Sometimes this use was tactical; in other instances, it reflected a belief that a conspiracy theory, one consistent with white nationalism, according to which cultural Marxists were destroying American society from within. (shrink)

'Shades of Goodness' is aimed at readers interested in moral theories, and particularly those wishing to construct or defend a moral theory.

This paper draws on nearly two decades of research on health consumer and patients’ organizations in the United Kingdom. In particular, it addresses questions of representation and legitimacy in the health policy process. HCPOs claim to represent the collective interests of patients and others such as relatives and carers. At times they also make claims to represent the wider public interest. Employing Pitkin’s classic typology of formalistic, descriptive, symbolic, and substantive representation, the paper explores how and in what sense HCPOs (...) represent their constituencies. We found that policymakers themselves are less concerned with formal mechanisms adopted by groups and are more concerned with credibility, in particular whether HCPOs carry the confidence of their constituents. While some concerns about legitimacy remain, particularly in relation to funding from commercial interests, we argue that HCPOs bring a unique perspective to the policy process and to focus purely on formalistic representation provides only a partial understanding of their representative role and a constrained view of their collective moral claims. (shrink)

It has been estimated that three species on the planet now go extinct every hour and that this rate is orders of magnitude higher than the planet has seen in previous catastrophic extinction events. We clearly are in the midst of a sixth extinction, and this one is different from the previous five. Why? This sixth extinction is caused by the activity of a single species—us. If there is any hope of ameliorating this extinction, it will entirely be up to (...) us, as the current stewards of this planet, to change the course. There are many challenges, though, to marshaling this effort. Two primary ones immediately come to mind. The first is that we simply haven't found the right biological tools to address this crisis. The second is that many humans on this planet don't even admit we have a problem. These are two very different problems. The first is primarily technological. Only recently has some of the more advanced biologically focused technology been available to conservation biology and extinction science. Humans are enthralled by cutting‐edge technology for the most part, and for the public, one of the more exciting possibilities in the realm of conservation biology is that some of the more charismatic species that have gone extinct might be resurrected through next‐generation technologies. While our discussion will articulate some weaknesses with the de‐extinction approach to conservation biology, we suggest that the “sexiness” of the technologies used in de‐extinction may simultaneously provide a definition of the techniques viable in conservation biology and afford a teachable moment. (shrink)

Nothing is more mysterious for man than the substance of his own body. Every society has attempted in its way to give a particular answer to this primary enigma in which man has his roots. Innumerable theories of the body that have followed each other during the course of history or that still coexist today are directly connected to the world views of these different societies. Even more, they are dependent on the conceptions of the person. The modern view of (...) the body, that which anatomo-physiology incarnates, is a direct function of the emergence and development of individualism within the European societies of the Renaissance, especially in the 17th century, that marks a crystallization, very clear at the social level, of this tendency. Moreover, the explosion of the present knowledge of the body that makes anatomophysiology one theory among others, even though it is dominant, denotes another stage in individualism, a yet stronger falling back on the ego: the emergence of a society in which the atomization of individuals has become an important fact, an atomization submitted to or desired, according to the case, which does not appear in contradiction to present research in new ways of socializing, new forms of tribalism and so on, as is clearly indicated by what we agree to call the associative phenomenon. This is a characteristic of societies in which individualism is a structural fact: the development of an infinitely plural and polyphonic character. In these societies, in fact, the initiative is assumed by individuals or groups more than it is in a culture that tends to become a simple formal framework. (shrink)

This article argues against the view put forward by Margaret Archer that there is an irreconcilable divide between realist social theory and structuration theory. Instead, it argues for the systematic articulation of the two theories at both the ontological and the methodological levels. Each has developed a range of insightful and commensurable conceptualizations either missing or underdeveloped in the other. Archer's contention that structuration theory rejects the notion of `analytical dualism' central to the realist approach is shown to be mistaken; (...) Giddens's rejection of `dualism' refers to a different conceptualization of the term. Similarly, Archer's critique of structuration's notion of a `duality' involving structure and agency is rejected by showing that Archer's own morphogenetic approach itself relies upon such a notion. A final section distinguishes between six key problematics of social analysis. It is clear that, for a large number of possible questions within the majority of these problematics, it is a combination of both ontologies that would facilitate the most adequate substantive account. (shrink)

E.O. Wilson (1975) described humans as one of the four pinnacles of social evolution. The other pinnacles are the colonial invertebrates, the social insects, and the non-human mammals. Wilson separated human sociality from that of the rest of the mammals because, with the exception of the social insect like Naked Mole Rats, only humans have generated societies of a grade of complexity that approaches that of the social insects and colonial invertebrates. In the last few millennia, human societies have even (...) begun to exceed, in numbers of individuals and degree of complexity, the societies of ants, termites, and corals. (shrink)

Bijural services as factors of production -- Commentary A on Breton and Salmon -- Commentary B on Breton and Salmon -- The challenge of incomplete law and how different legal systems respond -- Commentary C on Pistor and Xu -- Commentary D on Pistor and Xu -- Coevolution as an influence in the development of legal systems -- Commentary E on Breton and Des Ormeaux -- Commentary F on Breton and Des Ormeaux -- The demand for (...) bijurally trained Canadian lawyers -- Commentary G on Davis and Trebilcock -- Commentary H on Davis and Trebilcock. (shrink)

Cet essai est un retour aussi réfléchi que possible sur l'ensemble de mes écrits de philosophie. S'étalant sur une durée approximative de cinquante-cinq ans, ils sont à la fois nombreux et, du fait de leur nombre, menacés par la dispersion. Je suis bien conscient de l'objection possible ainsi que de la demande, toujours plus réitérée depuis 1990, d'une quasi-synthèse, de la part de lecteurs qui, à diverses reprises, m'ont fait part de leur sympathie et de leur encouragement. Je me suis (...) promis de les satisfaire par un bref écrit qui serait, à ma façon, et sans égaler le modèle qui de loin m'inspire, une quasi-monadologie. J'ai le sentiment, dans ce retour sur mon passé, de devoir beaucoup à ceux qui, au cours de mon cheminement, m'ont aidé dans ce long travail de pensée. Ma première interrogation serait donc celle-ci : " Qu'as-tu que tu n'aies reçu? STANISLAS BRETON. (shrink)

Aesthesis, the classical term for sensing and perceiving, is at the heart of innumerable problems that plague global society. The purpose of this article is to open a conversation on aesthesis. We survey the roots and relevance of aesthesis as a direct albeit contested relation and engagement with the world and with Others. From its pre-Socratic origins, aesthesis has been both a pragmatic, somatic concept, prompting a re-evaluation of the distinction between experience and abstraction. We trace its ongoing repression from (...) Plato through ‘western’ theories of formal Aesthetics. Drawing on a relational interpretation of Protagoras’ aesthesis, we argue that modern pragmatists and radical empiricists, as well as more contemporary critics of the ‘colonization’ of aesthesis (Mignolo and Vasquez) by formal Aesthetics recognize and develop the relational and ethical aspects of aesthesis. We consider the role of the body, affect, and of the intangible or virtual qualities of aesthesis. The ethics of obligations (Weil) in the polis (Arendt) shows how aesthesis informs politics despite its repression in favour of moral and legal norms. We argue this is relevant to contemporary crises such as xenophobia and ecocidal climate warming. (shrink)

Animal and plant species exhibit an astonishing diversity of sexual systems, including environmental and genetic determinants of sex, with the latter including genetic material in the mitochondrial genome. In several hermaphroditic plants for example, sex is determined by an interaction between mitochondrial cytoplasmic male sterility (CMS) genes and nuclear restorer genes. Specifically, CMS involves aberrant mitochondrial genes that prevent pollen development and specific nuclear genes that restore it, leading to a mixture of female (male‐sterile) and hermaphroditic individuals in the population (...) (gynodioecy). Such a mitochondrial‐nuclear sex determination system is thought to be rare outside plants. Here, we present one possible case of CMS in animals. We hypothesize that the only exception to the strict maternal mtDNA inheritance in animals, the doubly uniparental inheritance (DUI) system in bivalves, might have originated as a mitochondrial‐nuclear sex‐determination system. We document and explore similarities that exist between DUI and CMS, and we propose various ways to test our hypothesis. (shrink)

This paper develops and explores a pedagogical innovation for integrating virtue theory into business students' basicunderstanding of general management. Eighty-seven students, in 20 groups, classified three managers' real-time videotaped activitiesaccording to an elaboration of Aristotle's cardinal virtues, Fayol's management functions, and Mintzberg's managerial roles. The study's empirical evidence suggests that, akin to Fayol's functions and Mintzberg's roles, Aristotle's virtues are also amenable to operationalization, reliable observation, and meaningful description of managerial behavior. The study provides an oft-called-for empirical basis for further (...) work in virtue theory as an appropriate conceptual framework for the study and practice of management. The results indicate that virtue theory may be used to re-conceive our fundamental understanding of management, alongside its capacity to weigh moral judgment upon it. implications and suggestions for future research are discussed. (shrink)

Interactive technology assessment is a novel approach to evaluating (health) technology, which philosophically draws from the works of Rawls and Habermas. That is, it seeks to organise a practical setting for discursive ethics in order to find a legitimate basis for policy to be pursued when the technology under scrutiny features a moral controversy. Interactive technology assessment involves a cycle of interviews with all stakeholders, who are explicitly asked to respond (anonymously) to the concerns and issues raised by other participants. (...) This cycle is completed repeatedly, so that a process of vicarious learning develops. This process aims at identifying issues agreed and disagreed upon, on the basis of which widely endorsed policy recommendations can be formulated. This chapter involves an interactive technology assessment of paediatric cochlear implantation. The rationale, the design, and the results are explained, as well as the main ethical aspects of the procedure. (shrink)