During the past decade, it has become apparent that it is within our grasp to understand fully the development and functioning of complex organisms. It is widely accepted that this undertaking must include the elucidation of the genetic blueprint – the genome sequence – of a number of model organisms. As a prelude to the determination of these sequences, clonebased physical maps of the genomes of a number of multicellular animals and plants are being constructed. Yeast artificial chromosome (YAC) vectors, (...) by virtue of their relatively unbiased cloning capabilities and capacity to carry large inserts, have come to play a central role in the construction of these maps. The application of YACs to the physical map of the Caenorhabditis elegans genome has enabled cosmid clone ‘islands’ to be linked together in an efficient manner. The long‐range continuity has improved the linkage between the genetic and physical maps, greatly increasing its utility. Since the genome can be represented by a relatively small number of YACs, it has been possible to make replica filters of genomically ordered YACs available to the community at large. (shrink)

Disturbance-generated biomass results from endogenous and exogenous natural and cultural disturbances that affect the health and productivity of forest ecosystems. These disturbances can create large quantities of plant biomass on predictable cycles. A systems analysis model has been developed to quantify aspects of system capacities (harvest, transportation, and processing), spatial aspects of the biomass generation process, and deterioration impacts on biomass quality in the various inventory states (field stands, field-harvested inventories, transportation prepared inventories, and production facility inventories). Optimal decision alternatives (...) can be used to guide responses to reclamation, utilization, mitigation, and control. This is particularly advantageous in insect and disease outbreaks, in which the process may last several years, with varying levels of intensity. The prescriptive system description, assuming capacities are fixed, results in a linear programming model. The time-dependent capacity decision model results in a mixed-integer programming model. The analytical model is developed in detail in this analysis. (shrink)

This book sets the record straight about the greater influence of Dilthey than Husserl in Heidegger’s initial formulation of his conception of phenomenology. Scharff shows how, in Heidegger’s early lecture courses, phenomenology is presented as a genuine philosophical alternative, and explores our own current need for a phenomenological philosophy.

This paper considers recent heated debates led by Jerry A. Coyne andMichael J. Wade on issues stemming from the 1929–1962 R.A. Fisher-Sewall Wrightcontroversy in population genetics. William B. Provine once remarked that theFisher-Wright controversy is central, fundamental, and very influential.Indeed,it is also persistent. The argumentative structure of therecent (1997–2000) debates is analyzed with the aim of eliminating a logicalconflict in them, viz., that the two sides in the debates havedifferent aims and that, as such, they are talking past each other. (...) Given aphilosophical analysis of the argumentative structure of the debates,suggestions supportive of Wade's work on the debate are made that areaimed, modestly, at putting the persistent Fisher-Wright controversy on thecourse to resolution. (shrink)

It is true for many disciplines within the humanities that there are numerous excellent works that introduce the beginner to the basic building blocks of the discipline, and also many advanced studies for the accomplished scholar, but few works that help the student get from the beginning stage to the advanced level. That has certainly been true of the discipline of Sanskrit. Once a student has devoted a couple of years to working through one of the excellent introductions to the (...) language by Ashok Aklujkar, Michael Coulson, Madhav Deshpande, Robert Goldman, or Walter Maurer, there have been hardly any intermediate texts to help the student systematically progress to more advanced levels. Now, however, with the publication of Scholastic Sanskrit, an important step has been taken toward filling that lacuna. This book assumes that the student has learned enough about Sanskrit grammar and syntax to be ready to begin plunging into the vast corpus comprising the many genres of Sanskrit literature. It is built on the conviction that even a student at the early stages of exploring Sanskrit literature can benefit from the work of traditional commentators; it is also built on the observation that until now there have not been reliable guides to help the student make intelligent use of Sanskrit commentaries. (shrink)

Hastings Center Report, Volume 52, Issue 3, Page 18-29, May–June 2022.

In a recent article, Iris Marion Young raises several challenges to deliberative democracy on behalf of political activists. In this paper, the author defends a version of deliberative democracy against the activist challenges raised by Young and devises challenges to activism on behalf of the deliberative democrat. Key Words: activism • deliberative democracy • Discourse • Ideology • public sphere • I. M. Young.

Expressions of gratitude abound. Hardly a book is published that does not include in its preface or acknowledgments some variation on, “I am grateful to…for…” Indeed, most achievements come to be only through the help of others. We value the benevolence of others, and when we—or our loved ones—are the recipients of benevolence, our emotional response is often one of gratitude. -/- But, are we bound to the requirement of ‘repaying’ our benefactors in some way? If we are, and there (...) are—as ordinary language suggests—debts of gratitude, what kind of debts are these? Does the appropriateness of my gratitude require that my benefactor in fact intended to benefit me (in just the way she did)? Is there a difference between feeling grateful and being grateful? Is a precondition of my being grateful to another that I respect her? Do we owe a special sort of gratitude to those who have shaped us into the persons we are? What are the psychological and normative relations between gratitude the emotion, and gratitude the virtue? -/- These are among the questions carefully addressed in The Moral Psychology of Gratitude. This volume provides readers with the state-of-the-art in research on gratitude. It does so in the form of sixteen never-before published articles on the emotion by leading voices in philosophy and the sciences of the mind. (shrink)

In this book, W. V. Quine’s Immanuel Kant Lectures entitled Science and Sensibilia are published for the first time in English. These lectures represent an important stage in the development of Quine’s later thought, where he is more explicit about the importance of physicalist constraints in his account of the steps from sensory stimulation to scientific theory, and in further using them to assess the extent to which mental vocabulary is defensible. Taken as a unit, these lectures fill an important (...) gap in our understanding of his philosophical development from his 1973 work The Roots of Reference to his later work. The volume further contains an introduction that outlines the content and philosophical significance of the lectures. In addition, several essays written by leading scholars of Quine’s philosophy provide further insight into the important issues raised in the lectures. (shrink)

Two claims lay the foundation for Beyleveld and Brownsword’s legal theory. The first says that immoral laws cannot be law, the second that rights to freedom and welfare can be proven to be logically necessary given merely the phenomenon of agency. The author argues that both claims are too strong. The first is an overidealization of law, which fails to do justice to its double nature as a real as well as an ideal phenomenon. The second must fail, for a (...) moral “ought” cannot be deduced from a merely instrumental “ought.”. (shrink)

This article traces the evolution by which in the context of 1930s South Africa the liberal philosopher Alfred Hoernlé came to recognize the inability of classical liberalism to address the problems of a society in which a racial hierarchy had become deeply entrenched. Although he must be criticized for his patriarchal approach and for the pessimism that led him to take White attitudes toward Black South Africans as an unchangeable part of the situation that simply had to be accepted, his (...) insight into the limits of liberalism still resonates. While most White commentators were still thinking of racism in terms of beliefs and attitudes, he already understood that the problem lay in the systemic adoption of “techniques of domination” or what we today might call institutional racism. Although his proposal in 1939 that “Total Separation” was “a legitimate application of sound liberal ideas” was deeply problematic in context and might well have had a serious negative impact, it should be understood that it was intended to highlight the fundamental paradox into which liberalism fell when attempting to solve the problems it had helped to create by its belief in a civilizing mission that began with violence. (shrink)

Studies of fluctuating asymmetry (FA) in relation to sexual strategies in humans provide the empirical basis for many arguments in support of good genes sexual selection theory. Many FA studies, however, are flawed by bias in experimental design, inconsistent statistical analysis, and the sloppy handling of data.

Positions taken in the current debate over free will can be seen as responses to the following conditional: If every action is caused solely by another event and a cause necessitates its effect, then there is no action to which there is an alternative. The Libertarian, who believes that alternatives are a requirement of free will, responds by denying the right conjunct of C’s antecedent, maintaining that some actions are caused, either mediately or immediately, by events whose effects could be (...) different, even if they were to recur under identical circumstances. We have here a denial of Laplacian Determinism (LD), according to which the condition of the world at any instant makes only one state possible at any other instant.¹ One prominent defender of this view, Robert Kane, holds that unless an agent’s neural mechanisms operated indeterministicly in forming her character she is not responsible for its manifestations.² This requirement is entailed by the principle of “ultimate responsibility” (UR) according to which an act is freely willed only if (a) its agent is personally responsible for its performance in the sense of having caused it to occur by voluntarily doing something that was avoidable and (b). (shrink)

As an introduction to explicating the concept of basic knowledge, I shall examine Aristotle's argument for the existence of basic knowledge and urge two basic points. The first point is that Aristotle's argument, properly viewed, establishes the existence of a kind of knowledge, basic or non-demonstrative knowledge, the definition of which does not require the specification of, and hence the satisfaction of,anyevidence condition. This point has been urged by philosophers like Peirce and Austin but it needs further argumentation because most (...) analytic epistemologists still insist thatallknowledge, whether basic or non-basic, requires the satisfaction of some evidence condition. Secondly, to urge that the basic propositions whose existence is established by Aristotle's argument could be privileged but not known, for the reason that there is no evidence condition for them, would be to adopt a position that either entails wholesale skepticism or undermines the basic distinction between knowledge and belief. (shrink)

"A brilliant young scholar, Robert Neville, an ordained minister in the United Methodist Church teaching philosophy and theology at Fordham University, offers a new challenging theory of creation that defends religion in the Platonic-Augustinian tradition for the contemporary world. In preparing his argument, Neville orients his position with regard to contemporary alternatives--the existential philosophy of Paul Tillich, the neo-classical or process metaphysics of Charles Hartshorne, and the speculative Aristotelian philosophy of Paul Weiss. Neville approaches his theme, the problem of (...) the transcendence and the presence of God, in three ways. On one level the issue is metaphysical, and the author elaborates and argues for an abstract speculative theory of creation based on the dialectic of the one and the many; in doing so, he criticizes the views of Aquinas, Hegel, Royce, Wiess, and others. The issue on another level is epistemological, and the author offers a way of coping with modern criticisms of the metaphysics of creation, arguing that they theory of creation is not only intelligible but is demanded by the very structure of intelligibility. The author then applies the theory of creation to the practice of religion itself, applying abstract theory to creatin fundamental phenomena of religion to give experiential support to the earlier arguments. Speculation so sophisticated and daring will surely invite responses from both philosophers and theologians."-Publisher. (shrink)

What is Hell? Here is one answer: five straight days of conversation with a garrulous, narcissistic, rather depraved lawyer. This is the text, in fact the entire content, of Camus's brilliant quasi-religious novel, The Fall. The book has been read as a meditation on the "deadly" sin of pride, introducing a host of ethical and theological questions. I interpret the book as the story of a virtuous, contented, vulnerable man who is struck down by his own mistaken self-reflection and then (...) forced to re-establish his superiority by way of the resentment that replaces his pride. (shrink)

Robert Almeder provides a comprehensive discussion and definitive refutation of our common conception of truth as a necessary condition for knowledge of the world, and to defend in detail an epistemic conception of truth without falling into the usual epistemological relativism or classical idealism in which all properties of the world turn out to be linguistic in nature and origin. There is no other book available that clearly and thoroughly defends the case for an epistemic conception of truth and (...) also claims success in avoiding idealism or epistemological relativism. (shrink)

_Philosophical Conversations_ is a light, informal, and contemporary introduction to the study of philosophy. Using a dialogue format, Robert M. Martin delves into the traditional questions of philosophy in a manner that readers will find engaging. These substantive yet entertaining conversations emphasize that philosophical questions are contested and open-ended. The characters in each dialogue advocate different answers to questions on religion, ethics, personal identity, and other topics equitably and without naming any clear winners. Philosophic positions are presented with maximum (...) clarity and persuasiveness, so that readers can appreciate all sides of an issue and make their own choices. An excellent tool for newcomers to philosophy, _Philosophical Conversations_ provides the necessary background for further study while vividly portraying the back-and-forth argument that is essential to the philosophical method. (shrink)

Confusing clinical standoffs, loyalty to self-destruction and abrupt terminations are challenging and under-examined problems for the modern psychoanalytic practitioner. _The Danger of Change_ is a timely book that addresses the so-called resistant patient so many clinicians are familiar with. Robert Waska blends theory based on Melanie Klein’s classical stance with the more contemporary Freudian/Kleinian school, to demonstrate how to understand patients that are resistant to progress. Divided into four sections, this book covers: reluctant patients and the fight against change: (...) caught between the paranoid and depressive world greed and the dangers of change interruptions to the process of change: loss, envy, and the death instinct working toward change in the face of overwhelming odds Extensive and detailed clinical material is used to bring clarity to subjects including symbolism, conflict resolution, projective identification, the depressive and paranoid positions, change and trust. _The Danger of Change_ brings hope and clarity to cases involving patients who experience progress as a threat to their emotional wellbeing. It will be of great interest to all practising psychoanalysts, as well as those studying psychoanalytic theory and practice. (shrink)

We distinguish two conceptions of confinement – the agential conception and the comparative conception – and show that the former is intimately related to use in a way that the latter is not. Specifically, in certain conditions, agential confinement constitutes use and creates a special relationship that makes neglect or abuse especially egregious. This allows us to develop and defend an account of one important way in which agential confinement can be morally wrong. We then discuss some of the account’s (...) practical implications, including its usefulness for decision-making in real-world contexts in which animals are confined. (shrink)