This article argues the necessity of overcoming the hierarchical and pyramidal conception of the central nervous system that has subordinated the motor function to the higher brain activities for at least the last 150 years. The evolution of some motor modes of behavior?such as the ability to construct and manipulate instruments?has given rise to an ?embodied logic? underpinning not only the development of models of action and prediction but also the production of gestures and sequences of syllables that are at (...) the basis of human communication. Whether it is a matter of shaking someone's hand, writing a letter, or whatever, each executive function?controlled by a series of nervous structures and mental procedures that process the information?requires behaviors that are oriented to a specific end. (shrink)

Research on Augmented Reality in education has demonstrated that AR applications designed with diverse components boost student motivation in educational settings. However, most of the research conducted to date, does not define exactly what those components are and how these components positively affect student motivation. This study, therefore, attempts to identify some of the components that positively affect student motivation in mobile AR learning experiences to contribute to the design and development of motivational AR learning experiences for the Vocational Education (...) and Training level of education. To identify these components, a research model constructed from the literature was empirically validated with data obtained from two sources: 35 students from four VET institutes interacting with an AR application for learning for a period of 20 days, and a self-report measure obtained from the Instructional Materials Motivation Survey. We found that the following variables: use of scaffolding, real-time feedback, degree of success, time on-task and learning outcomes are positively correlated with the four dimensions of the ARCS model of motivation: Attention, Relevance, Confidence, and Satisfaction. Implications of these results are also described. (shrink)

Free will is usually defined by three conditions: the ability to do otherwise; control of one’s own choices; responsiveness to reasons. The compatibility of free will with determinism lies at the heart of the philosophical debate at the metaphysical level. This debate, while being increasingly refined, has not yet reached a conclusion. Recently, neuroscience and empirical psychology have tried to settle the problem of free will with a series of experiments that go in the direction of so-called illusionism: free will (...) as the conscious control of our behavior cannot exist, being a mere illusion. But even in this case, the experimental results are challenged at various levels. Considering that in most moral and legal systems, the subject’s liability derives from their freedom, the usefulness of preserving the concept of freedom – which incidentally responds to a very strong commonsensical intuition – suggests the need for an operational solution. This could be done by resorting to the concepts of capacity and cognitive control, which are measured by a set of well-established neuropsychological tests. Our preliminary proposal is to create an index, the first step towards a specific quantification and measurement of free will, to be used especially in ethical and legal contexts. Theoretical premises, practical difficulties and objections to this approach are also discussed and addressed. (shrink)

The ability to distinguish between emotions is considered indicative of well-being, but does emotion differentiation in an aesthetic context also reflect deeper and more knowledgeable aesthetic experiences? Here we examine whether positive and negative ED in response to artistic stimuli reflects higher fluency in an aesthetic domain. Particularly, we test whether knowledge of the arts and curiosity are associated with more fine-grained positive and negative aesthetic experiences. A sample of 214 people rated their positive and negative feelings in response to (...) various artworks including positive and negative themes. Positive ED was associated with the embracing sub-trait of curiosity that reflects engagement and enjoyment of novelty and complexity, but was unrelated to artistic knowledge and perceived comprehension. Negative ED was associated with higher curiosity and particularly more knowledge of the arts. This relationship was mediated by appraised comprehension suggesting that deeper engagement with art, by those with more art knowledge, is associated with more fine-grained emotional experiences. This finding extends ED beyond well-being research and suggests that more nuanced emotional experiences are more likely for those with expertise in the arts and motivation for exploration. (shrink)

This volume presents a collection of about 80 very brief, accessible essays written by international experts from medicine, social sciences, and the humanities, ...

Se presentan los resultados obtenidos en la tesis de maestría Sistema de talleres de trabajo educativo para la capacitación del profesor guía de Medicina en Nuevitas con el objetivo de demostrar el impacto a partir de su implementación en la brigada estudiantil. Se exponen las definiciones elaboradas y las contextualizaciones. Se concluye que el sistema contribuyó al adecuado desempeño del profesor guía y al desarrollo del modo de actuación de los estudiantes. La rapidez y la calidad que implicó en la (...) praxis educativa constituyó el resultado más importante en el contexto de la carrera de Medicina en la Filial. Results achieved through the master's thesis "Educational work workshops system for the Medicine degree guiding teacher training" in Nuevitas are presented, aimed at demonstrating its impact starting from its implementation on a class. Elaborate definitions and contexts are exposed. The conclusionreached through it was that the system contributed to the adequate guiding teacher's performance and to the development of students' behavior. The speed and quality it involved in educational praxis constituted the most important result in the context of the Medicine degree in La Filial town. (shrink)

The winds of change sweeping across our globalised world have inspired a wide range of studies, new research paradigms, and new concepts that seek to characterise their nature and effects, the chal...

Interleukin‐15 (IL‐15) is a pleiotropic cytokine of the 4 α‐helix bundle family, which binds to a receptor complex that displays common elements with the IL‐2 receptor and a unique high‐affinity α chain. This review focuses on juxtacrine and reverse signaling levels in the IL‐15/IL‐15R system. Specifically, we discuss how agonistic stimulation of membrane‐bound IL‐15 induces phosphorylation of members of the MAP kinase family and of focal adhesion kinase (FAK), thereby upregulating processes including cytokine secretion, cell adhesion and migration. In addition, (...) we explore IL‐15 trans‐presentation and intracellular signaling, and define promising molecular targets for future pharmacological intervention in infectious diseases and immunological disorders. These frontiers in IL‐15/IL‐15Rα research serve as highly instructive examples for key concepts, unsolved problems and therapeutic opportunities in juxtacrine and reverse signaling in general. BioEssays 28: 362–377, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Simone Weil (1909-1943) was one of the foremost French philosophers of the 20th century; a mystic, activist, and writer whose profound work continues to intrigue and inspire today. -/- Mirror of Obedience collects together Weil's poetry and autobiographical writings translated into English for the first time. It offers a rare glimpse into a more personal and introspective Weil than we usually encounter. She was writing and re-working her poems until the end of her life and in a letter from London (...) to her parents, dated 22 January 1943, she expressed the wish for her verses to appear together in print in chronological order, a wish which this volume honours. -/- Weil was a thinker who wrote with discipline and spareness and cherished the poetic form for its power to compress language and distill meaning. In these poems and literary writings, we see her own efforts to craft poems as essential expressions of thought, bringing into view another aspect of Weil's quest for beauty and truth. (shrink)

Introduction: The high degree of religious/spiritual involvement that brings meaning and purpose to a patients’ life, especially when they are weakened by pain, is among the various reasons to consider the spiritual dimension in clinical practice. This involvement may influence medical decisions and, therefore, should be identified in the medical history of a patient.Objective: To verify the opinion of undergraduate medical students of the Paulista School of Medicine – Federal University of São Paulo regarding the use of a patient’s Spirituality/Religiosity (...) as a therapeutic resource in clinical practice.Method: Quantitative approach of the transversal analytical observational type. The sample was composed of academics’ medical program, from the first to the sixth year, regularly enrolled in 2017. Data collection was performed with a standardized questionnaire divided into three sections: sociodemographic profile; Duke University Religious Index; Spirituality/Religiosity in the clinical and academic context.Results: Participated in the survey 72% of the enrolled students, of which 61.4% had religious affiliation, 26.2% declared themselves agnostic and 12.4% atheists. All of them proposed to answer questions about the insertion of Spirituality/Religiosity in the patient care process. Through the Duke Religiosity Index, we evaluated the importance of religiosity in the student’s personal life and the pertinence of religiosity as a therapeutic insertion for medical treatment. Regarding the clinical and academic context, most participants considered relevant the proposition of didactic-pedagogical actions in medical education related to the spiritual dimension of the patient.Conclusion: We conclude, through our research, that the insertion of the Spirituality/Religiosity of the patient as a therapeutic resource in clinical practice is feasible for most undergraduate students in Medicine of the Escola Paulista de Medicina – Universidade Federal de São Paulo. The result of the research, although it shows only the opinion of medical students at a Brazilian university, indicates that Spirituality/Religiosity is already part of the contemporary medical universe. (shrink)

En el trabajo se propone difundir la teoría y los enfoques referidos a la ciencia de la sostenibilidad, con especial énfasis en el contexto académico cubano, al relacionar su emergencia a las urgencias que surgen en los vínculos entre la ciencia, la naturaleza y la sociedad, así como mostrar las articulaciones de la Ciencia de la Sostenibilidad con la política científica, la educación universitaria y la salud pública. In this paper, the theory and the approaches of the science of sustainability (...) is promoted. Special emphasis is put on the academic Cuban context, when relating its emergence to the urgencies that appear within the links among science, nature and society. The interconnections of the science of sustainability with the scientific policy, the university education and the public health is shown as well as. (shrink)

This paper presents a new diachronic corpus of the Italian language, i.e., CODIT (COrpus Diacronico dell’ITaliano ‘Diachronic corpus of Italian’). After a description of the corpus design, the second part of the article is devoted to show possible applications of the corpus in the morphological field, specifically in the domain of evaluative morphology. We highlight the corpus’ strengths and limitations through the diachronic analysis of two affixes, i.e., sopra- and -oide. The study contributes to shed light on the dynamism of (...) evaluative morphology by focusing on the loss of the intensification function suffered by sopra- and the emergence of an approximating value that currently affects -oide. (shrink)

En el contexto de cambios del proceso de globalización, la medicalización constituye una problemática central en la agenda de salud internacional. Durante la década de 1990, comenzó la expansión internacional del diagnóstico de trastorno por déficit de atención e hiperactividad (TDAH), entre otros factores, merced a la creciente relevancia de actores no médicos en el proceso y de legislaciones específicas para diferentes diagnósticos. El artículo busca contribuir a un análisis del espacio que le otorga la prensa escrita on line a (...) los procesos de medicalización del TDAH en Argentina en el siglo XXI, como aporte a una lectura panorámica de los procesos en la región y a nivel internacional, y como contribución a un área de vacancia en los estudios sociales. Para este artículo, analizamos 236 artículos on line de periódicos argentinos de alcance nacional y provincial entre 2001 y 2017. Para el relevamiento se diseñaron mecanismos de selección y filtro, con criterios y herramientas de búsqueda y procesamiento de noticias. Se efectuaron estimaciones de regularidad de tópicos emergentes y procesamientos parciales de información, incluyendo, entre otras dimensiones, año, jurisdicción, medio, fecha, sección, título, categoría, características de la nota, palabras clave, concepto o nombre del problema, fármaco/droga, tratamiento, actores sociales y recomendaciones. Con el artículo nos interesa engrosar los todavía escasos estudios que aportan a la comprensión de cómo el diagnóstico de TDAH está migrando a diferentes regiones del globo y, más específicamente, cómo está posicionándose como un problema de salud internacional. Los resultados muestran que, en los procesos de medicalización del TDAH en niños y niñas, la prensa escrita argentina (nacional y provincial) se constituye en un actor no médico relevante tanto en la institucionalización de la problemática como en la presentación de líneas terapéuticas a seguir y en acciones orientadas al impulso de legislaciones específicas. (shrink)

The question of the dimensionality of space has informed the development of physics since the beginning of the twentieth century in the quest for a unified picture of quantum processes and gravitation. Scientists have worked within various approaches to explain why the universe appears to have a certain number of spatial dimensions. The question of why space has three dimensions has a genuinely philosophical nature that can be shaped as a problem of justifying a contingent necessity of the world. In (...) contrast to explanations of three-dimensionality based on anthropic arguments, we support the search for a theory that provides a justification for the dimensionality of space based on a combination of deductive and inductive reasoning applied to science. In doing so, we argue that Kant correctly approached the question in “Thoughts on the true estimation of living forces” by connecting space dimensionality and the inverse square law. In expounding the strategy of Kant’s argument, we describe the main features of a general Kantian explanation of the dimensionality of space and discuss them with respect to current accounts of explanation in the philosophy of science, such as inference to the best explanation and the deductive-nomological model. (shrink)

In the period of emergence of early modern science, ‘monsters’ or individuals with physical congenital anomalies were considered as rare events which required special explanations entailing assumptions about the laws of nature. This concern with monsters was shared by representatives of the new science and Late Scholastic authors of university textbooks. This paper will reconstruct the main theses of the treatment of monsters in Late Scholastic textbooks, by focusing on the question as to how their accounts conceived nature’s regularity and (...) teleology. It shows that they developed a naturalistic teratology in which, in contrast to the naturalistic explanations usually offered by the new science, finality was at central stage. This general point does not impede our noticing that some authors were closer to the views emerging in the Scientific Revolution insofar as they conceived nature as relatively autonomous from God and gave a relevant place to efficient secondary causation. In this connection, this paper suggests that the concept of the laws of nature developed by the new science –as exception-less regularities—transferred to nature’s regularity the ‘strong’ character that Late Scholasticism attributed to finality and that the decline of the Late Scholastic view of finality played as an important concomitant factor permitting the transformation of the concept of laws of nature. (shrink)

This essay argues that despite of the feminist critique of Merleau-Ponty his phenomenology can be positively appropriated to the theory of sexual difference. It focuses on three issues: the first one is closely linked to the Phenomenology of Perception and introduces a concept of "difference as differentiation". The second one is concerned with the intersubjective dimension of sexuality and will be called a "sexual syncretism". Finally, I’m referring to Merleau-Ponty's notion of "chiasm" in his late work The Visible and the (...) Invisible in order to apply it to the theory of sexual difference. At this point, the difference between sexual beings will be conceptualized as "chiasmatic intertwining". In doing so, I hope to show that Merleau-Ponty's phenomenology is a helpful resource for philosophical research that is mainly concerned with the questions of sexuality and sexual difference. (shrink)