Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Beauvoir maintains a unified "compromise theory" of aesthetics throughout her ethics, feminism, and fiction that portrays the conundrum that every artist faces -- an impasse that sets action against inaction, politics against culture. Beauvoir's theory of art in The Mandarins, aided by an analysis of women's oppression in The Second Sex, advocates art that keeps past events alive in the present and in so doing, changes even the tragic into the life affirming. Beauvoir lauds artists who, even in the face (...) of self-doubt, continue to engage in artistic endeavors in order to maintain an ethical relationship to the rest of humanity. (shrink)

This paper provides an exposition and critical assessment of a fundamental disagreement between Løgstrup’s and Levinas’s otherwise closely aligned ethical phenomenologies. The disagreement concerns the putative compatibility of ethics and ontology, where in stark contrast to Levinas’s ethics, which proceeds from a critique of the ‘primacy of ontology’ in Western thought, Løgstrup brands his own ethical project as ‘ontological ethics’. First, I provide an interpretation of Løgstrup’s ontological ethics, clarifying in particular the influence of hermeneutic and existential analysis on Løgstrup’s (...) methodology. Second, I bring Løgstrup’s ontological ethics into critical dialogue with Levinas’s thought. Here, I home in on two Levinas-style worries that appear to have traction against Løgstrup’s ontological ethics. However, ultimately, I argue that both can be defused. (shrink)

The article examines Marin Cureau de La Chambre's Système de l'âme (1664), highlighting the role played in the work by the tradition of Italian Renaissance naturalism. La Chambre profoundly criticizes the very concept of 'passion of the soul', attacking the Aristotelian doctrine of the possible intellect but, contemporarily, also the direct interaction between body and mind presupposed by Descartes in Les passions de l'âme. The solution adopted by Cureau is based on the doctrine of intermediate substances, which allows him to (...) resume Ficino's model, reconciling it with Descartes' intellec-tualist dualism and integrating the latter with a panpsychism of Campanellian brand. (shrink)

This article examines some of the ways in which the trope of coldness appears in the social theory of Theodor W. Adorno. In the first section, I show how and why Adorno repeatedly criticizes a certain brand of coldness, namely, ‘bourgeois coldness’, which is understood as enacting and encouraging formal abstraction and indifference to sensuous particularity. In this sense, coldness is seen to function as a precondition for severe forms of violence (both symbolic and material). However, in the second (...) section, I argue that stopping short at this one-sided ‘critique of coldness’ remains incomplete and undialectical, and does not do justice to Adorno’s more complicated engagement with the topic. In light of this, I invert the focus of analysis to the ‘coldness of critique’, claiming that there are examples of other forms, internalizations and uses of coldness in Adorno’s work, serving to indefatigably expand the utopian horizons of his social theory above and beyond piecemeal reformism, local pedagogy or pragmatic micro-politics. The aim is not simply to promote ostensibly ‘positive’ alternatives or remedies to the ‘negative’ symptom of coldness, but rather to tarry with the negative, to recognize the coldness within ourselves the better to break through and sublate it. For Adorno, there is no way around coldness; the only way is to go through it. (shrink)

Praise and Reviews `Thom Braun`s mission, in this eclectic and readable book, is to get us thinking and, whether he`s relating Plato to Persil or Descartes to Diet Coke, that`s just what he does. No marketer will think about their job in the same way after reading this. Enjoyable and thought-provoking` James Thompson, Senior Vice President, Marketing, Diageo, North America `Thom Braun, The Thinking Man`s Brand Manager, has created a whole new sizzling discourse on branding which provides a terrific (...) antidote to the anodyne filler of standard business texts. Armed with brains and a little Braun, brand managers can become brand leaders.` Paul Walton, Chairman, The Value Engineers `An original and witty reminder that the most successful brands are driven by talented thinkers.` Simon Clift, President, Marketing, Unilever Home & Personal Care `At last, a brand book with a big idea. Braun`s entertaining distillation of some of the greatest thinkers of the last 3,000 years offers provocative yet practical conclusions on how we should rethink managing our own brand. A wonderfully fresh and stimulating read.` Adam Morgan, author of Eating the Big Fish `A thoroughly stimulating and enjoyable read. By looking at brands and branding through the lens of Western philosophy, Braun helps us review afresh some of the fundamentals of marketing.` Jim Carroll, Deputy Chairman, BBH London In this original and imaginative slant on contemporary brand management, Thom Braun takes us into the minds of the worlds greatest Western thinkers... Heraclitus Socrates Plato Aristotle Descartes Spinoza Leibniz Locke Hume Rousseau Kant Hegel Nietzsche Wittgenstein Popper...to reveal what they might say about branding if they were alive today. Filled with contemporary examples, pragmatic insights and summaries of each philosopher's "top tips", this elegant and witty book will resonate with all marketing and branding professionals who want their intellectual and professional faculties stimulated by some new thinking. (shrink)

Although it is not yet officially recognized as a clinical entity which is diagnosable, Internet Gaming Disorder (IGD) has been included in section III for further study in the DSM-5 by the American Psychiatric Association (APA, 2013). This is important because there is increasing evidence that people of all ages, in particular teens and young adults, are facing very real and sometimes very severe consequences in daily life resulting from an addictive use of online games. This article summarizes general aspects (...) of IGD including diagnostic criteria and arguments for the classification as an addictive disorder including evidence from neurobiological studies. Based on previous theoretical considerations and empirical findings, this paper examines the use of one recently proposed model, the Interaction of Person-Affect-Cognition-Execution (I-PACE) model, for inspiring future research and for developing new treatment protocols for IGD. The I-PACE model is a theoretical framework that explains symptoms of Internet addiction by looking at interactions between predisposing factors, moderators, and mediators in combination with reduced executive functioning and diminished decision making. Finally, the paper discusses how current treatment protocols focusing on Cognitive-Behavioral Therapy for Internet addiction (CBT-IA) fit with the processes hypothesized in the I-PACE model. (shrink)

This volume presents fourteen original essays which explore the philosophy of Simon Blackburn, and his lifetime pursuit of a distinctive projectivist and anti-realist research program. The essays document the range and influence of Blackburn's work and reveal, among other things, the resourcefulness of his brand of philosophical pragmatism.

Since male CEOs dominate corporate leadership, the literature on top management decision making suffers from an implicit masculine bias. Although research indicates that males and females are biologically and psychologically different, the leadership characteristics of female CEOs are largely unexplored. Two of these characteristics, risk aversion and ethical sensitivity, are tied to key accounting issues, such as conservatism in financial reporting and steadfast opposition to fraud. In this study, we examine the relationship between CEO gender and accounting conservatism, and find (...) a positive association between the two. Consistent with conventional wisdom, this association appears to be stronger in firms with high rather than low litigation and takeover risks. This study contributes to the ethics literature by highlighting the benefits of gender diversity in upholding the integrity of financial reporting. (shrink)

Inspired by Sara Ahmed’s notion of ‘queer use,’ I present and extend a neo-Aristotelian theory of artifacts to capture what I call ‘counter-use.’ The theory of artifacts is based on the idea that what they are, how they come to be, and what their functions are cannot be understood independently from each other. They come to exist when a maker imposes the concept of their substantial kind onto some matter by working on the matter to make an artifact of that (...) kind out of it. The extensions to this core theory that I describe are two. First, I show how using can be a kind of making and how disparate users may form what Benedict Anderson calls an imagined community. Second, I describe what I call an artifact’s historicity and suggest that, like its substantial kind, an artifact’s historicity is essential to it. On this basis, I characterize counter-use as use of an artifact by an imagined community that re-arranges an object’s historicity and hence brings into existence a numerically distinct object. Thus, politically motivated counter-use has genuine ontological implications. (shrink)

Gopal Sreenivasan’s “hybrid theory” states that a moral duty is directed toward an individual because her interests justify the assignment of control over the duty. An alternative “plain theory” states that the individual’s interests justify the duty itself. I argue that a strong moral status constraint explains Sreenivasan’s instrumentalization objection to a Razian plain theory but that his own model violates this constraint. I suggest how both approaches can be reformulated to satisfy the constraint, and I argue that a reformulated (...) plain theory can also avoid an insufficiency objection. The hybrid approach consequently has no clear advantage over the plain approach. (shrink)

I argue against Rawls's claim that the liberal principle of legitimacy would be selected in the original position in addition to a democratic principle. Since a religious democracy could satisfy the democratic principle, the parties in the original position would not exclude it as illegitimate.

The reconstruction of Leibniz’s metaphysics that Deleuze undertakes in The Fold provides a systematic account of the structure of Leibniz’s metaphysics in terms of its mathematical foundations. However, in doing so, Deleuze draws not only upon the mathematics developed by Leibniz—including the law of continuity as reflected in the calculus of infinite series and the infinitesimal calculus—but also upon developments in mathematics made by a number of Leibniz’s contemporaries—including Newton’s method of fluxions. He also draws upon a number of subsequent (...) developments in mathematics, the rudiments of which can be more or less located in Leibniz’s own work—including the theory of functions and singularities, the Weierstrassian theory of analytic continuity, and Poincaré’s theory of automorphic functions. Deleuze then retrospectively maps these developments back onto the structure of Leibniz’s metaphysics. While the Weierstrassian theory of analytic continuity serves to clarify Leibniz’s work, Poincaré’s theory of automorphic functions offers a solution to overcome and extend the limits that Deleuze identifies in Leibniz’s metaphysics. Deleuze brings this elaborate conjunction of material together in order to set up a mathematical idealization of the system that he considers to be implicit in Leibniz’s work. The result is a thoroughly mathematical explication of the structure of Leibniz’s metaphysics. This essay is an exposition of the very mathematical underpinnings of this Deleuzian account of the structure of Leibniz’s metaphysics, which, I maintain, subtends the entire text of The Fold. (shrink)

David Lewis's cohabitation theory suffered damaging criticism from Derek Parfit. Though many have defended versions of Lewis's theory Parfit's criticism has not been answered. This paper shows how to defend the cohabitation theory against Parfit's criticism.

Graham Harman’s Object-Oriented Ontology has employed a variant of occasionalist causation since 2002, with sensual objects acting as the mediators of causation between real objects. While the mechanism for living beings creating sensual objects is clear, how nonliving objects generate sensual objects is not. This essay sets out an interpretation of occasionalism where the mediating agency of nonliving contact is the virtual particles of nominally empty space. Since living, conscious, real objects need to hold sensual objects as sub-components, but nonliving (...) objects do not, this leads to an explanation of why consciousness, in Object-Oriented Ontology, might be described as doubly withdrawn: a sensual sub-component of a withdrawn real object. (shrink)

We use a new model of metarepresentational development to predict a cognitive deficit which could explain a crucial component of the social impairment in childhood autism. One of the manifestations of a basic metarepresentational capacity is a ‘ theory of mind ’. We have reason to believe that autistic children lack such a ‘ theory ’. If this were so, then they would be unable to impute beliefs to others and to predict their behaviour. This hypothesis was tested using Wimmer (...) and Perner’s puppet play paradigm. Normal children and those with Down’s syndrome were used as controls for a group of autistic children. Even though the mental age of the autistic children was higher than that of the controls, they alone failed to impute beliefs to others. Thus the dysfunction we have postulated and demonstrated is independent of mental retardation and specific to autism. (shrink)

Within a year of each other, three one-volume general dictionaries of philosophy have recently appeared; when our future colleagues in philosophy look back on the 1990s they may well think of it as the decade of reference works. But however productive these years may prove to be in this genre, clearly visible somewhere around the top of the heap will be this handy, useful, entertaining, and instructive contribution from Simon Blackburn. Its two immediate competitors are the Cambridge Dictionary of (...) Philosophy, edited by Robert Audi, and the Oxford Companion to Philosophy, edited by Ted Honderich. No detailed comparison will be attempted here, but two points stand out as obviously giving Blackburn’s dictionary a rather different use and flavor from the others: while containing a closely comparable number of entries, it is distinctly shorter and handier in format; and it has all been written by a single author. (shrink)

The Harivaṃśa has usually been seen as a later addition appended to the Mahābhārata, and so the Mahābhārata has usually been understood without it. This article first introduces an alternative approach, whereby these two texts are viewed as a single whole, and justifies that approach on the basis of the details presented in Mbh 1.2. Then the Harivaṃśa’s narrative mechanics are summarized, to contextualize what follows. The main body of the article offers three kinds of answer to the title question (...) of what difference the Harivaṃśa makes to the Mahābhārata. The first answer is theological: the Harivaṃśa emphasizes the divine level of the Mahābhārata story as the story of the gods descending to help the earth. The second answer is narratological: the Harivaṃśa continues and completes the story of Janamejaya begun in Mbh 1, thus emphasizing his role for the text as a whole. The third answer is structural: if the Mahābhārata includes the Harivaṃśa then the whole text can be studied and analyzed as a macrocompositional unit. The “Mahābhārata as a whole” has been the subject of collaborative study in recent years, and this article continues that study, with regard to a fuller whole. The article, unlike that whole, is short, sketchy, and provisional. It looks forward to further and corrective studies in all the sketched areas, and more. (shrink)

Steroid‐hormone‐activated receptor proteins are among the best‐understood class of factors for altering gene transcription in cells. Steroid receptors are of major importance in maintaining normal human physiology by responding to circulating concentrations of steroid in the nM range. Nonetheless, most studies of steroid receptor action have been conducted using the supra‐physiological conditions of saturating concentrations (≥100 nM) of potent synthetic steroid agonists. Here we summarize the recent developments arising from experiments using two clinically relevant conditions: subsaturating concentrations of agonist (to (...) mimic the circulating concentrations in mammals) and saturating concentrations of antagonists (which are employed in endocrine therapies to block the actions of endogenous steroids). These studies have revealed new facets of steroid hormone action that could not be uncovered by conventional experiments with saturating concentrations of agonist steroids, such as a plethora of factors/conditions for the differential control of gene expression by physiological levels of steroid, a rational approach for examining the gene‐specific variations in partial agonist activity of antisteroids, and a dissociation of steroid potency and efficacy that implies the existence of separate, and possibly novel, mechanistic steps and cofactors. BioEssays 30:744–756, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Today’s technological-scientific prospect of posthumanity simultaneously evokes and defies historical understanding. On the one hand, it implies a historical claim of an epochal transformation concerning posthumanity as a new era. On the other, by postulating the birth of a novel, better-than-human subject for this new era, it eliminates the human subject of modern Western historical understanding. In this article, I attempt to understand posthumanity as measured against the story of humanity as the story of history itself. I examine the fate (...) of humanity as the central subject of history in three consecutive steps: first, by exploring how classical philosophies of history achieved the integrity of the greatest historical narrative of history itself through the very invention of humanity as its subject; second, by recounting how this central subject came under heavy criticism by postcolonial and gender studies in the last half-century, targeting the universalism of the story of humanity as the greatest historical narrative of history; and third, by conceptualizing the challenge of posthumanity against both the story of humanity and its criticism. Whereas criticism fragmented history but retained the possibility of smaller-scale narratives, posthumanity does not doubt the feasibility of the story of humanity. Instead, it necessarily invokes humanity, if only in order to be able to claim its supersession by a better-than-human subject. In that, it represents a fundamental challenge to the modern Western historical condition and the very possibility of historical narratives – small-scale or large-scale, fragmented or universal. (shrink)

On the basis of three physical axioms, we prove that if the choice of a particular type of spin 1 experiment is not a function of the information accessible to the experimenters, then its outcome is equally not a function of the information accessible to the particles. We show that this result is robust, and deduce that neither hidden variable theories nor mechanisms of the GRW type for wave function collapse can be made relativistic and causal. We also establish the (...) consistency of our axioms and discuss the philosophical implications. (shrink)

This article examines Derrida's critique of Hegel. It argues that there are two key issues that Derrida misunderstands in Hegel's thought: first, Hegel's response to the concept-intuition dichotomy that plagued Kant's critical thought; second, that Hegel's notions of reason and the dialectic, when they are conceived non-metaphysically, are not tools employed to subsume differences but are, like Derrida's différance , fundamentally concerned with thought's instability. The article shows the way in which Derrida develops the notion of singularity by an examination (...) of the discussion of responsibility in his later writings. It is argued that the way that Hegel and Derrida consider the notion of singularity is a much better marker for distinguishing these two thinkers than Derrida's own interpretation of Hegel. Key Words: Jacques Derrida • dialectic • differance • G. W. F. Hegel • normativity • reason • responsibility • singularity. (shrink)

This special issue focuses on two related topics in Ernst Cassirer’s thought: objectivity and truth. Through this lens, the guest editors attempt to illuminate (a) the historical and systematic value of Cassirer’s philosophical project, (b) the continuing relevance of his account of the plurality and universality of human understanding in view of the crisis of truth that currently permeates Western culture, and (c) the way Cassirer’s style can inspire contemporary scholars who wish to evade the analytic-continental divide. Tobias Endres and (...) Simon Truwant gathered twelve contributions from more analytic oriented authors from the philosophy of science and more continental oriented authors from the philosophy of culture. By bringing these scholars together on a shared topic, they hope to help bridging this divide that is also reflected within Cassirer scholarship by preoccupation with either his philosophy of science or philosophy of culture. The articles in this special issue are preceded by a ceremonial speech that Cassirer gave on the occasion of his assumption of the rectorate of the University of Hamburg on November 7, 1929 and that was translated into English for the first time by the guest editors. (shrink)

Rationale One's understanding of medical progress – what it is, how it is pursued and how it is assessed – may be deeply dependent on one's understanding of the metaphysics of medicine, and of diseases in particular. -/- Aims and Objectives In this paper I present a new account of the nature of diseases, neither realist nor constructivist, and describe what progress in medicine looks like if we understand diseases in this way. -/- Conclusions This new account, Constructive Realism, may (...) provide a better account of medicine than either realism or constructivism. (shrink)

Why Plantinga's updated (2009) version of the Free Will Defense does not work, and consequently the Logical Argument From Evil against the God of Theism is undefeated.

Bohr’s interpretation of quantum mechanics has been criticized as incoherent and opportunistic, and based on doubtful philosophical premises. If so Bohr’s influence, in the pre-war period of 1927–1939, is the harder to explain, and the acceptance of his approach to quantum mechanics over de Broglie’s had no reasonable foundation. But Bohr’s interpretation changed little from the time of its first appearance, and stood independent of any philosophical presuppositions. The principle of complementarity is itself best read as a conjecture of unusually (...) wide scope, on the nature and future course of explanations in the sciences (and not only the physical sciences). If it must be judged a failure today, it is not because of any internal inconsistency. (shrink)

In a series of philosophical discussions and artistic case studies, this volume develops a materialist and immanent approach to modern and contemporary art. The argument is made for a return to aesthetics--an aesthetics of affect--and for the theorization of art as an expanded and complex practice. Staging a series of encounters between specific Deleuzian concepts--the virtual, the minor, the fold, etc.--and the work of artists that position their work outside of the gallery or "outside" of representation--Simon O'Sullivan takes Deleuze's (...) thought into other milieus, allowing these "possible worlds" to work back on philosophy. (shrink)

Dreier’s sympathy with expressivism is welcome, and yet he comes upon an ‘uncomfortable surprise’, in a circularity or regress that he detects in my attempt to place ethical commitments in a natural world. The circularity is that the expressivist analysis of what is going on, when we invoke norms, identifies particular states of mind: valuings, or acceptance of norms, or complexes of attitude. But states of mind are themselves normatively tainted. Hence: ‘the kernel of expressivist analysis invokes normative concepts’.

Williams’s arguments against the morality system are given canonical form in Ethics and the Limits of Philosophy, chapter 10, where he undertakes to describe this particular form of ethical thinking and explain “why we would be better off without it”.

An examination of the controversial "theory of mind" hypothesis, which states that children with autism are unable to comprehend other people's mental states. The theory relates to the most fundamental questions of normal development as well as to autism i.

Who's better? Billie Holiday or P. J. Harvey? Blur or Oasis? Dylan or Keats? And how many friendships have ridden on the answer? Such questions aren't merely the stuff of fanzines and idle talk; they inform our most passionate arguments, distil our most deeply held values, make meaning of our ever-changing culture. In Performing Rites, one of the most influential writers on popular music asks what we talk about when we talk about music. What's good, what's bad? What's high, what's (...) low? Why do such distinctions matter? (shrink)

In Menkiti’s Moral Man, Oyowe argues that Menkiti’s persons are “soft persons.” They are different in kind from human beings in that they find their existence in a social ontology, whereas humans find theirs in a natural ontology, but this does not make them any less real. This understanding, Oyowe contends, is consistent with Menkiti’s texts and allows for a satisfying explanation of a possibly problematic relationship between human being and person. He acknowledges that their placement in social ontology makes (...) them (at least partly) conventional entities and so opens Menkiti’s account to some of the threats that face conventionalism, but he goes on to argue that these can be overcome. This article argues against Oyowe that Menkiti’s persons are resistant to the interpretation as soft entities. Though Menkiti continually stresses the importance of the community to personhood, much of what he has to say suggests he ascribes neither to the distinction between social and natural ontology that is central to Oyowe’s interpretation nor to the conventionalism that comes with it. This article argues that the soft-person reading does not solve problems of conventionalism as neatly as Oyowe hopes but that Menkiti’s view is not vulnerable to those problems. (shrink)

This book presents a detailed analysis of what it means to be absorbed in playing music. Based on interviews with one of the world’s leading classical ensembles, “The Danish String Quartet”, it debunks the myth that experts cannot reflect while performing, but also shows that intense absorption is not something that can be achieved through will, intention, prediction or planning – it remains something individuals have to be receptive to. Based in the phenomenological tradition of Husserl and Merleau-Ponty as well (...) as of Dan Zahavi and Shaun Gallagher, it lays out the conditions and essential structures of musical absorption. Employing the lived experience of the DSQ members, it also engages and challenges core ideas in phenomenology, philosophy of mind, enactivism, expertise studies, musical psychology, flow theory, aesthetics, dream and sleep studies, psychopathology and social ontology, and proposes a method that integrates phenomenology and cognitive science. (shrink)

By focusing discussion through Søren Kierkegaard's view of Martin Luther's initiation into the monastery , it is suggested that an analogy can be discerned for Kierkegaard's own sense of divine vocation and the ensuing self‐mortification of melancholy and religious scrupulosity which commentators have suspected in both figures. Kierkegaard's often ambivalent critique of Luther's Anfechtung is thus read as bearing ironic significance for his own struggles with ‘spiritual trial’ [Anfægtelse]. In this reading, Luther's Anfechtung is taken to signify for Kierkegaard both (...) the anguish inherent to the authentic God‐relationship and also the dangerous possibility of the individual imagination's [Phantasi] capitulation into the precariously embellished realm of ‘the fantastic’ [Phantastiske]. It is here that Kierkegaard's emphasis upon individual responsibility – contrasted with Luther's concentration upon the role of the devil – demonstrates the fundamental differentiation between Kierkegaard's anatomy of Anfægtelse and Luther's Anfechtung. (shrink)

From Plato's _Republic_ and Aristotle's _Poetics_ to Nietzsche's _The Birth of Tragedy_, the theme of tragedy has been subject to radically conflicting philosophical interpretations. Despite being at the heart of philosophical debate from Ancient Greece to the Nineteenth Century, however, tragedy has yet to receive proper treatment as a philosophical tradition in its own right. _Philosophy and Tragedy_ is a compelling contribution to that oversight and the first book to address the topic in a major way. Eleven new essays by (...) internationally renowned philosophers clearly show how time and again, major thinkers have returned to tragedy in many of their key works. _Philosophy and Tragedy_ aks why it is that thinkers as far apart as Hegel and Benjamin should make tragedy such an important theme in their work, and why, after Kant, an important strand of philosophy should present itself tragically. From Heidegger's reading of Sophocles' Antigone to Nietzsche and Benjamin's book-length studies of tragedy, _Philosophy and Tragedy_ presents an outstanding and original study of this preoccupation. The five sections are organised clearly around five major philosophers: Hegel, Holderlin, Nietzsche, Heidegger, and Benjamin. (shrink)

Sinnott-Armstrong's paper principally defends our inability to justify, philosophically, normal moral claims. In particular, we cannot justify them against other claims, especially the claim of moral nihilism. Moral nihilism is the doctrine that there are no moral obligations. This thesis ‘does not lie in meta-ethics. It is a universally quantified substantive moral claim’. Sinnott-Annstrong makes it clear that he does not actually believe this doctrine, but he believes that it is coherent, and that a variety of strategies philosophers might attempt (...) all fail to disprove it. And because of this, ordinary claims to obligation are philosophically unjustified. (shrink)

Anne McNevin’s book provides a valuable contribution to ongoing debates about the plight of irregular migrants in the context of neoliberal hegemony. It combines detailed analysis of contemporary movements that resist the ever-increasing controls over borders and movement, together with critical assessments of a range of contemporary theorists on the question. McNevin’s central argument is that neoliberalism not only delineates the migrant subject in various ways, but also traps activists into replicating many harmful assumptions about ‘deserving’ versus ‘undeserving’ migrants. She (...) further argues for a resurrection of the political subjectivity of migrant communities, by both exploiting the crisis engendered at the nexus of neoliberal economics and the sovereign subject, and resisting the framework set by those paradigms. (shrink)

Hans Lipps’s originality lies in a tension between his hermeneutical and existential philosophy on the one hand, and his analysis of themes belonging to classical logic, on the other. To understand this tension, it must be examined at its point of origin – when Lipps discusses Husserl’s philosophy. The purpose of this text is to explain the opposition between Lipps and his first Master. Lipps’s critique of Husserl concerns transcendental idealism, the transcendental reduction, and the concept of intentionality, which appear (...) to Lipps as an escape from the realm of facticity. Husserlian idealism is then similar to Kant’s critical philosophy. Pursuing his inquiry from the perspective of facticity, Lipps refutes Kant’s and Husserl’s transcendentalism and their focus on the realm of representation. He tries nevertheless to analyse the classic problems of phenomenology and Kantian logic from the point of view of facticity. (shrink)

Michel Foucault's concept of bio-politics entails the management and regulation of life processes within the population as a whole. This administration of the biological was perhaps most manifest in the German state under National Socialism. Indeed, Foucault remarks that there was no other state of the period in which "the biological was so tightly, so insistently regulated." However while the Nazi regime evinced this bio-political concern with the management of life, it also released an unprecedented murderous potential. It is this (...) paradox, that the care of life can become the administration of death, or what Foucault deemed the transition from bio-politics to thanato-politics, that I wish to investigate through an examination of the construction of the Jewish subject through Nazi medical discourse. This paper will examine how medico-political discourse facilitated the construction of medically authorized norms that constructed the Jew as both a biological and social threat to the body politic, and how this discursively produced "Other" informed the transition from bio-politics to thanato-politics within the confines of the German medical establishment. (shrink)

In Schleiermacher's thought, according to romanticism, history and historical evolution can only be understood as the revelation and realisation of an idea within empiric world. At the end of this evolution there will be the identity of Geist and nature, idea and reality. – For Schleiermacher church history ist the middle discipline of historical theology. Between 1806 and 1826 he held three lectures on this subject and made diverse attempts to appoint the relation in which church history stands to universal (...) history and to the idea of knowledge and science. (shrink)

One implication of Godel’s Proof is that, as Barry Barnes has observed, “For people to operate...rationally they need to have internalized some non-rational commitment to rationality”. In which case “The customary Enlightenment formula, according to which the process of demagification of the world leads necessarily from mythos to logos, seems . . .” Gadamer suggests, “. . . to be a modern prejudice”, or myth. Yet some myths are more useful than others, and therefore it may be on pragmatic grounds (...) that, following Nietzsche’s characterization of “. . . logic and the categories of reason as means to . . . useful falsification . . .” we may wish to resist the abandonment of reason that many take to be the corollary of its deconstruction. (shrink)