Epigenetics – the study of mechanisms that influence and modify gene expression – is providing unique insights into how an individual’s social and physical environment impact the body at a molecular level, particularly in populations that experience stigmatization and trauma. Researchers are employing epigenetic studies to illuminate how epigenetic modifications lead to imbalances in health outcomes for vulnerable populations. However, the investigation of factors that render a population epigenetically vulnerable present particular ethical and methodological challenges. Here we are concerned with (...) demonstrating how, in targeting certain populations for epigenetic research, this research may be pathologizing socio-cultural and medical practices in those populations in a way that increases their vulnerability. Using a case study approach, this article examines three vulnerable populations currently of interest to epigenetic researchers – Indigenous, autistic, and transgender populations – in order to highlight some of the challenges of conducting non-stigmatizing research in epigenetics. (shrink)

Plausibly, only moral agents can bear action-demanding duties. Not all groups are moral agents. This places constraints on which groups can bear action-demanding duties. Moreover, if such duties imply ability then moral agents – of both the individual and group varieties – can only bear duties over actions they are able to perform. I tease out the implications of this for duties over group actions, and argue that groups in many instances cannot bear these duties. This is because only groups (...) with the right kind of structure – groups I call ‘collectives’ – have the agency to bear action-demanding duties. Yet neither can individuals bear these duties, assuming that individuals cannot perform group actions and that duty implies ability. This appears to leave us at a loss when assigning duties to perform some group actions. I argue we can solve this problem by assigning collectivization duties to individuals – duties to form a collective that then incurs a duty over the action. I give criteria for when individuals have collectivization duties and discuss the demands these duties place on their bearers. (shrink)

Why, morally speaking, ought we do more for our family and friends than for strangers? In other words, what is the justification of special duties? According to partialists, the answer to this question cannot be reduced to impartial moral principles. According to impartialists, it can. This paper briefly argues in favour of impartialism, before drawing out an implication of the impartialist view: in addition to justifying some currently recognised special duties, impartialism also generates new special duties that are not yet (...) widely recognised. Specifically, in certain situations, impartial principles generate duties to take actions and adopt attitudes in our personal lives that increase the chance of new or different special relationships being formed—new or different friendships, family-like relationships, relationships akin to co-nationality, and so on. In fact, even if one thinks partialism is the best justification of the duties we have once in special relationships, impartialist justifications for taking steps to form such relationships should have some sway. Moreover, a little reflection shows that these duties are not as demanding or counterintuitive as one might expect. (shrink)

This examination of gardens--particulary English gardens of the eighteenth century--offers possible links between garden design and the arts.

Ignoring the temporal dimension, an object such as a railway tunnel or a human body is a three-dimensional whole composed of three-dimensional parts. The four-dimensionalist holds that a physical object exhibiting identity across time—Descartes, for example—is a four-dimensional whole composed of 'briefer' four-dimensional objects, its temporal parts. Peter van Inwagen (1990) has argued that four-dimensionalism cannot be sustained, or at best can be sustained only by a counterpart theorist. We argue that different schemes of individuation of temporal parts are available, (...) which undermines van Inwagen's argument. (shrink)

The Cambridge History of Medieval Philosophy comprises over fifty specially commissioned essays by experts on the philosophy of this period. Starting in the late eighth century, with the renewal of learning some centuries after the fall of the Roman Empire, a sequence of chapters takes the reader through developments in many and varied fields, including logic and language, natural philosophy, ethics, metaphysics, and theology. Close attention is paid to the context of medieval philosophy, with discussions of the rise of the (...) universities and developments in the cultural and linguistic spheres. A striking feature is the continuous coverage of Islamic, Jewish, and Christian material. There are useful biographies of the philosophers, and a comprehensive bibliography. The volumes illuminate a rich and remarkable period in the history of philosophy and will be the authoritative source on medieval philosophy for the next generation of scholars and students alike. (shrink)

We applaud Domjan et al. for providing an elegant account of Pavlovian feed-forward mechanisms in social behavior that eschews the pitfall of purposivism. However, they seem to imply that they have provided a complete account without provision for operant conditioning. We argue that operant conditioning plays a central role in social behavior, giving examples from fish and infant behavior.

Couples therapy has long been regarded as one of the most demanding forms of psychotherapy because of the way it challenges therapists to combine the insights of dynamic psychology with the power and clarity of systems dynamics. In this exciting new volume, Gordon Wheeler and Stephanie Backman, couples therapists with broad training and long years of experience, present dramatic new approaches that at last integrate the dynamic/self-organizational and the systemic/behavioral schools of thought. Building on the insights of Gestalt psychology (...) and psychotherapy, the authors show us how a truly phenomenological approach, based on the clients' own experience and goals, holds the key to a dramatic increase in therapeutic power and flexibility. The fifteen engaging chapters demonstrate the application of this approach to issues of intimacy, self-construction, power and abuse, "resistance," growth, and shame - and to such diverse and challenging populations as abuse survivors and their partners, remarried couples, gay and lesbian couples, and couples with "personality" or "character" disorders. In the process, the authors offer a fresh perspective that will serve to re-energize the couples therapist's work in this challenging area. _On Intimate Ground_ contributes new insights to many of the most timely and provocative questions in the field today. (shrink)

When making decisions on behalf of someone, is asking what they would have wanted a good way to respect their autonomy? Against prevalent assumptions, I argue that in decisions about the care and treatment of those with advanced dementia, the notion of ‘what one would have wanted’ is conceptually, epistemically, and practically problematic. The problem stems from the disparity between the first-person subjectivity of the past person and that of the present person. The transformative nature of dementia renders the very (...) meaning of ‘what the patient would have wanted’ problematic. When applied to those with advanced dementia, the subjunctive notion is either (i) incoherent, (ii) fundamentally indeterminate, or (iii) normatively irrelevant. (shrink)

The American Journal of Bioethics, Volume 12, Issue 10, Page 9-10, October 2012.

The Cambridge History of Medieval Philosophy comprises over fifty specially commissioned essays by experts on the philosophy of this period. Starting in the late eighth century, with the renewal of learning some centuries after the fall of the Roman Empire, a sequence of chapters takes the reader through developments in many and varied fields, including logic and language, natural philosophy, ethics, metaphysics, and theology. Close attention is paid to the context of medieval philosophy, with discussions of the rise of the (...) universities and developments in the cultural and linguistic spheres. A striking feature is the continuous coverage of Islamic, Jewish, and Christian material. There are useful biographies of the philosophers, and a comprehensive bibliography. The volumes illuminate a rich and remarkable period in the history of philosophy and will be the authoritative source on medieval philosophy for the next generation of scholars and students alike. (shrink)

Boyer's cognitive model of ownership, based on cooperation and competition, underscores the importance of studying disagreements in ownership. We argue that exploring the factors that can lead to different perceptions and experiences of ownership will uniquely inform our understanding of legal, psychological, and perceived ownership beliefs.

We present evidence supporting the target article's assertion that while the presentation of base-rate information in a natural frequency format can be helpful in enhancing sensitivity to base rates, method of presentation is not a panacea. Indeed, we review studies demonstrating that when subjects directly experience base rates as natural frequencies in a trial-by-trial setting, they evince large base-rate neglect.

The primary goal of this article is point out certain close parallels between some ideas of the radical feminist theorist Mary Daly and those of the French philosopher Henri Bergson. These similarities are particularly striking regarding distinctions made by both authors between two fundamentally contrasting types of cognitive faculty, of time and temporal experience, and of self and emotion. Daly departs from Bergson inasmuch as she employs these distinctions in her own way. She does not—like Bergson—employ them to depict the (...) result of a natural process of consciousness or life, and the dangers for human freedom and thought of not properly respecting these differences. Rather, she locates these differences within a more liberatory, ethical perspective to ground a sharp, inimical contrast between feminist creative movement on the one hand, and static, fixing, and “fixating” patriarchy, with its “technocratic” pretensions, on the other. My hope is that highlighting the similarities between Daly and Bergson will open new paths of appreciation and critique of Daly’s work. (shrink)

The goal of this study is to characterize observers’ abilities to detect gradual changes and to explore putative dissociations between conscious experience of change and behavioral adaptation to a changing stimulus. We developed a new experimental paradigm in which, on each trial, participants were shown a dot pattern on the screen. Next, the pattern disappeared and participants had to reproduce it. In some conditions, the target pattern was incrementally rotated over successive trials and participants were either informed or not of (...) this change. We analyzed both awareness of the changes and the dynamics of behavioral adaptation, in a way that makes it possible to assess both variability and accuracy as they change over time. Results indicate a dissociation between change awareness and behavioral adaptation to the changes, and support the notion that unconscious representations of visual stimuli are more precise and detailed than previously suggested. We discuss the implications of these results for theories of change detection. (shrink)

This Introduction offers a conceptualization of the Indo-Pacific, its islands and their place within the history of science. We argue that Indo-Pacific islands present a remarkable combination of social, political and spatial circumstances, which speak to themes that are central to the history of science. Having driven movements of people and represented staging grounds for explorations, expansions and cross-cultural exchanges, these spaces have been at the forefront of historical change. The historiographies of the two oceans have traditionally emphasized indigenous agency (...) while downplaying European historical trajectories, and therefore they provide historians of science with materials and methodologies that promise nuanced portrayals of knowledge production in cross-cultural settings. Rather than unifying the oceans into a cohesive narrative, we seek to uncover the many horizons of Indo-Pacific worlds and pluralize the spaces within which knowledge travelled at specific times, but not at others. Offering a middle plane between the globe and the region, islands are particularly productive sites for such analyses, as they bring to attention both localized kinds of agency and the impacts of colonialism and globalization. This special issue investigates what happens to knowledge within island spaces and demonstrates that even as small strips of land, islands can significantly enhance our understanding of the practices of knowledge making within the broader contours of world history. In bringing to the fore the contributions of actors from across the wider social spectrum and, especially, the interacting roles of indigenous agents and their traditions, Indo-Pacific worlds thus offer exciting new directions for a field which has often been dominated by a focus on European institutions. (shrink)

Competitive athletes act within cultures of risk in sports and often decide to return to sport despite having acute health problems. The outcomes of such risky return-to-play decisions can not only negatively affect their future health, but also limit their sports performance or even upset their career paths. Following risk-management-decision theory with its focus on active risk defusing, we developed a model for understanding the process of return-to-play decision making from an athlete’s perspective. Based on the method of active information (...) search, a quasi-naturalistic return-to-play decision scenario was created in order to assess amateur team sport athletes’ decision making strategies. The main goals were to identify different information acquisition patterns and to analyze the influence of social pressure to play hurt on decision making. A total of 72 competitive team sport athletes (36 females, 36 males, m= 25.7 years of age, 3rd to 6th league level) out of three disciplines (volleyball, basketball, and handball) participated in the experimental study. Facing the same medical scenario (a partial tear of the supraspinatus tendon), athletes show different approaches to return-to-play decision making. The main focus is on potential sporting consequences of withdrawal from competition due to injury, while only few players favoring well-informed decisions based on thorough risk analysis. The athletes who chose the medically risky alternative to play hurt mostly employed strategies of active risk defusing, which got activated when severe sporting consequences were perceived. Those who chose to withdraw from competition primarily referred to maximin heuristic, particularly when social pressure to play was reduced. The findings can be used to improve rehabilitation. (shrink)

Open Humanities Press, Living Books About Life Series.

The "Dark Side" of Humour. An Analysis of Subversive Humour in Workplace Emails Although a substantial amount of research has investigated the various functions of humour in a workplace context, electronic means of communication have largely been ignored. This is particularly surprising since electronic communication in the workplace is increasingly gaining significance. This seems to be especially true for email, which in many workplaces is the preferred medium for communicating transactional as well as relational topics. Drawing on a corpus of (...) about 100 emails collected in an academic setting, we explore how humour is used in workplace emails. Our specific focus is on subversive humour, which often functions as a tool to express frustration and dissent, and ultimately to challenge existing power relations. Our analysis illustrates that subversive humour is an excellent means to make fun of established and normative workplace practices by exaggerating and ridiculing them, and to re-define organisational reality by offering alternative interpretations. These functions of subversive humour appear to be particularly useful for those in relatively powerful positions: by employing humour to convey critical and potentially threatening messages in acceptable ways, the senders manage to express their dissent and frustration with the wider organisational system while, at the same time, escaping the scrutiny of the very organisation that they are symbolically challenging. (shrink)

This chapter discusses the slow burn of development which has impacted the Chinese landscape for a long time, despite the country’s urbanization. Although China’s modernization has been underway for the last 150 years, the country’s current global visibility has been mistaken for a sudden eruption of modernity. China has been through a variety of struggles, and the struggle between beauty and pragmatism is portrayed in films about the poor and manifested through the class aspirations of the new rich. In this (...) regard, the landscaping of China is mostly a narrative of continuous and traumatic pressure inflicted by the people on the motherland. These signs of struggle are, therefore, what articulate the Chinese landscape as a work of destruction and reconstruction in constant progress. (shrink)

In eukaryotes, RNA trans‐splicing is an important RNA‐processing form for the end‐to‐end ligation of primary transcripts that are derived from separately transcribed exons. So far, three different categories of RNA trans‐splicing have been found in organisms as diverse as algae to man. Here, we review one of these categories: the trans‐splicing of discontinuous group II introns, which occurs in chloroplasts and mitochondria of lower eukaryotes and plants. Trans‐spliced exons can be predicted from DNA sequences derived from a large number of (...) sequenced organelle genomes. Further molecular genetic analysis of mutants has unravelled proteins, some of which being part of high‐molecular‐weight complexes that promote the splicing process. Based on data derived from the alga Chlamydomonas reinhardtii, a model is provided which defines the composition of an organelle spliceosome. This will have a general relevance for understanding the function of RNA‐processing machineries in eukaryotic organelles. (shrink)

“Persia beyond the Oxus.” Edited by M. Rahim Shayegan. Bulletin of the Asia Institute 21 : 147–96.

I applaud and elaborate on the contextualism at the heart of Bullot & Reber's (B&R's) theory, challenge two aspects of the appreciative structure they posit (the causal reasoning that allegedly underlies the design stance and the segregation of the component stages), suggest that expert and novice appreciators operate differently, and question the degree to which B&R's final theory is open to empirical investigation.

This article discusses the Tang Wei incident, which evolved across the first half of 2008, during the run-up to the Olympic Games in Beijing. Tang Wei is a Chinese actress whose breakthrough role in Ang Lee’s film Lust, Caution caused a sensation amongst Chinese audiences. The nudity and sex scenes in the film were explicit, and as such challenged accepted norms in film content. This aspect of the film, combined with the characterization of a national traitor as a heroine, caused (...) deep concern among some parties involved in film regulation and censorship. The argument presented here is that Tang Wei, who was singled out for criticism and upon whom travel and work restraints were placed in the aftermath of the film’s release, was made a scapegoat for the disgust experienced by a masculinist political class when faced with female dissent and sexuality. (shrink)

L'article examine les spécificités des forums de discussion proposés par les municipalités françaises au regard de quelques-unes des interrogations animant les réflexions sur la délibération. Le forum apparaît comme un lieu conflictuel où l'expression relève davantage du registre de l'émotionnel que de la seule argumentation rationnelle. Ce caractère polémique des échanges n'est pas cependant exempt du souci de l'intérêt général, les internautes tentent ainsi de monter en généralité à partir de leurs revendications personnelles. Les inégalités de compétence entre participants ne (...) disparaissent pas lors des échanges électroniques, notamment en raison d'une maîtrise différenciée de l'écriture, mais la prédominance discursive de l'institution municipale, qui accompagne habituellement les débats publics, est largement érodée. L'influence du forum dans l'espace public local se manifeste indirectement, à travers son instrumentalisation dans le cadre d'actions collectives. (shrink)

Que serait la philosophie de Platon sans Socrate ou l'écriture des dialogues? Que resterait-il du travail de Montaigne sans le 'maistre des maistres' socratique ou la 'manière' des Essais? Enfin, l'œuvre de Rancière aurait-elle la même teneur sans Joseph Jacotot, figure incontournable de 'maître ignorant'? La pensée de ces trois auteurs n'existe pas indépendamment de ces figures et de ces écritures si particulières. On ne saurait résumer leurs philosophies, par ailleurs très singulières et différentes, à quelques questions, thèses ou concepts, (...) en les amputant de la mise en scène de ces figures de maîtres si frappantes ou de l'invention stylistique qui leur donne corps et redouble, par les choix d'écriture, leurs gestes philosophiques. Ceci reviendrait à les trahir et à s'interdire l'expérience d'un autre rapport au savoir qu'elles nous invitent à vivre, chacune à sa façon. Cet ouvrage étudie comment ces trois philosophes pensent, à travers ces incarnations, leur relation aux savoirs de leur temps et dans quelle mesure les figures et les écritures de maîtres ignorants qu'ils composent et mobilisent dans leurs textes leur permettent de faire expérimenter au lecteur les gestes philosophiques significatifs de ce rapport au savoir."--Page 4 of cover. (shrink)

This chapter contains sections titled: Context: Hunting from an Anishinabe Perspective Teachings on Hunting Hunting and Awareness Notes.