In the rod‐shaped cells of E. coli, chromosome segregation takes place immediately after replication has been completed. A septum then forms between the two sister chromosomes. In the absence of certain membrane proteins, cells grow instead as large, multichromosomal spheres that divide successively in planes that are at right angles to one another. Although multichromosomal, the spherical cells cannot be maintained as heterozygotes. These observations imply that, in these mutants, each individual chromosome gives rise to a separate clone of descendant (...) cells. This suggests a model in which sites for cell division form between pairs of sister chromosomes at the time of segregation, but are not used in spherical cells until further rounds of replication have taken place, thus ensuring clonal (‘hierarchical’) segregation of chromosomes into progeny cells. The role of the morphogenetic membrane proteins is to convert the basically spherical cell into a cylinder that is able to divide as soon as replication and segregation have been completed, and thus to maximise the number of viable cells per genome. (shrink)

This study explores the nature of the conflict between science and religion. It shows through a detailed examination of this conflict as it was manifested in nineteenth century Britain that it is a fallacy that religion and science can co-exist in mutual harmony, since the legacy of their conflict in the past century has been inherited by this century, greatly to the detriment of religious belief. It is the author's contention that a return to the essentials of Kant's critical philosophy (...) would lay bare the profound differences between religious and scientific approaches to the world, and the nature of the choice people can make between them. In his effort to demarcate the outlines of a genuine Biblical theology (and to articulate the proper procedures for producing one) the author casts light on important questions of Biblical interpretation, and demands a radical reassessment of the meaning of science for society. (shrink)

What could someone represent that would enable her to track, at least within limits, others' perceptions, knowledge states and beliefs including false beliefs? An obvious possibility is that she might represent these very attitudes as such. It is sometimes tacitly or explicitly assumed that this is the only possible answer. However, we argue that several recent discoveries in developmental, cognitive, and comparative psychology indicate the need for other, less obvious possibilities. Our aim is to meet this need by describing the (...) construction of a minimal theory of mind. Minimal theory of mind is rich enough to explain systematic success on tasks held to be acid tests for theory of mind cognition including many false belief tasks. Yet minimal theory of mind does not require representing propositional attitudes, or any other kind of representation, as such. Minimal theory of mind may be what enables those with limited cognitive resources or little conceptual sophistication, such as infants, chimpanzees, scrub-jays and human adults under load, to track others' perceptions, knowledge states and beliefs. (shrink)

Are there distinct roles for intention and motor representation in explaining the purposiveness of action? Standard accounts of action assign a role to intention but are silent on motor representation. The temptation is to suppose that nothing need be said here because motor representation is either only an enabling condition for purposive action or else merely a variety of intention. This paper provides reasons for resisting that temptation. Some motor representations, like intentions, coordinate actions in virtue of representing outcomes; but, (...) unlike intentions, motor representations cannot feature as premises or conclusions in practical reasoning. This implies that motor representation has a distinctive role in explaining the purposiveness of action. It also gives rise to a problem: were the roles of intention and motor representation entirely independent, this would impair effective action. It is therefore necessary to explain how intentions interlock with motor representations. The solution, we argue, is to recognise that the contents of intentions can be partially determined by the contents of motor representations. Understanding this content-determining relation enables better understanding how intentions relate to actions. (shrink)

What is knowledge? How hard is it for a person to have knowledge? Good Knowledge, Bad Knowledge confronts contemporary philosophical attempts to answer those classic questions, offering a theory of knowledge that is unique in conceiving of knowledge in a non-absolutist way.

The Limits of Influence is a detailed examination and defense of the evidence for largescale-psychokinesis. It examines the reasons why experimental evidence has not, and perhaps cannot, convince most skeptics that PK is genuine, and it considers why traditional experimental procedures are important to reveal interesting facts about the phenomena.

On the traditional view, moral distress arises only in cases where an individual believes she knows the morally right thing to do but fails to perform that action due to various constraints. We seek to motivate a broader understanding of moral distress. We begin by presenting six types of distress that fall outside the bounds of the traditional definition and explaining why they should be recognized as forms of moral distress. We then propose and defend a new and more expansive (...) definition of moral distress and examine how it can enable the development of a taxonomy of moral distress. (shrink)

_On Being in the World_, first published in 1990, illumines a neglected but important area of Wittgenstein’s philosophy, revealing its pertinence to the central concerns of contemporary analytic philosophy. The starting point is the idea of ‘continuous aspect perception’, which connects Wittgenstein’s treatment of certain issues relating to aesthetics with fundamental questions in the philosophy of psychology. Professor Mulhall indicates parallels between Wittgenstein’s interests and Heidegger’s _Being and Time_, demonstrating that Wittgenstein’s investigation of aspect perception is designed to cast light (...) on much more than a bizarre type of visual experience: in reality, it highlights what is distinctively _human _about our behaviour in relation to things in the world, what it is that distinguishes our practical activity from that of automata. On Being in the World remains an invaluable resource for students of Wittgenstein’s philosophy, as well as anyone interested in negotiating the division between analytic and continental philosophy. (shrink)

Given the premise that joint action plays some role in explaining how humans come to understand minds, what could joint action be? Not what a leading account, Michael Bratman's, says it is. For on that account engaging in joint action involves sharing intentions and sharing intentions requires much of the understanding of minds whose development is supposed to be explained by appeal to joint action. This paper therefore offers an account of a different kind of joint action, an account compatible (...) with the premise about development. The new account is no replacement for the leading account; rather the accounts characterise two kinds of joint action. Where the kind of joint characterised by the leading account involves shared intentions, the new account characterises a kind of joint action involving shared goals. (shrink)

Here we challenge the orthodoxy according to which abduction is an a posteriori mode of inference. We start by providing a case study illustrating how abduction can justify a philosophical claim not justifiable by empirical evidence alone. While many grant abduction's epistemic value, nearly all assume that abductive justification is a posteriori, on grounds that our belief in abduction's epistemic value depends on empirical evidence about how the world contingently is. Contra this assumption, we argue, first, that our belief in (...) abduction’s epistemic value is not and could not be justified a posteriori, and second, that attention to the roles experience plays in abductive justification supports taking abduction to be an a priori mode of inference. We close by highlighting how our strategy for establishing the a priority of abduction positively contrasts with strategies in Bonjour (1998), Swinburne (2001), and Peacocke (2004) aiming to establish the a priority of certain ampliative modes of inference or abductive principles. (shrink)

Intuitions play an important role in contemporary epistemology. Over the last decade, however, experimental philosophers have published a number of studies suggesting that epistemic intuitions may vary in ways that challenge the widespread reliance on intuitions in epistemology. In a recent paper, Jennifer Nagel offers a pair of arguments aimed at showing that epistemic intuitions do not, in fact, vary in problematic ways. One of these arguments relies on a number of claims defended by appeal to the psychological literature on (...) intuitive judgment and on mental state attribution (also known as “theory of mind”, “mindreading” and “folk psychology”). I call this the "theoretical argument". The other argument relies on recent experimental work carried out by Nagel and her collaborators. It is my contention that in setting out her theoretical argument, Nagel offers an account of the relevant scientific literature that is, in crucial respects, flawed and misleading. My main goal in this paper is to rectify these errors and to make it clear that, once this is done, Nagel’s theoretical argument collapses. Since Nagel’s experimental work has not yet been published, and available details are very sketchy, I do not discuss this work in detail. However, in the final section of the paper I offer some critical observations about Nagel’s strategy for dealing with empirical data that does not support her view – both other people’s and her own. (shrink)

The processes whereby our brains continue to learn about a changing world in a stable fashion throughout life are proposed to lead to conscious experiences. These processes include the learning of top-down expectations, the matching of these expectations against bottom-up data, the focusing of attention upon the expected clusters of information, and the development of resonant states between bottom-up and top-down processes as they reach an attentive consensus between what is expected and what is there in the outside world. It (...) is suggested that all conscious states in the brain are resonant states and that these resonant states trigger learning of sensory and cognitive representations. The models which summarize these concepts are therefore called Adaptive Resonance Theory, or ART, models. Psychophysical and neurobiological data in support of ART are presented from early vision, visual object recognition, auditory streaming, variable-rate speech perception, somatosensory perception, and cognitive-emotional interactions, among others. It is noted that ART mechanisms seem to be operative at all levels of the visual system, and it is proposed how these mechanisms are realized by known laminar circuits of visual cortex. It is predicted that the same circuit realization of ART mechanisms will be found in the laminar circuits of all sensory and cognitive neocortex. Concepts and data are summarized concerning how some visual percepts may be visibly, or modally, perceived, whereas amodal percepts may be consciously recognized even though they are perceptually invisible. It is also suggested that sensory and cognitive processing in the What processing stream of the brain obey top-down matching and learning laws that are often complementary to those used for spatial and motor processing in the brain's Where processing stream. This enables our sensory and cognitive representations to maintain their stability as we learn more about the world, while allowing spatial and motor representations to forget learned maps and gains that are no longer appropriate as our bodies develop and grow from infanthood to adulthood. Procedural memories are proposed to be unconscious because the inhibitory matching process that supports these spatial and motor processes cannot lead to resonance. (shrink)

….it [is] wholly irrational to regard as doubtful matters that are perceived clearly and distinctly by the understanding in its purity, on account of mere prejudices of the senses and hypotheses in which there is an element of the unknown.Descartes, Geometrical Exposition of the MeditationsSubstance dualism, once a main preoccupation of Western metaphysics, has fallen strangely out of view; today’s mental/physical dualisms are dualisms of fact, property, or event. So if someone claims to find a difference between minds and bodies (...) per se, it is not initially clear what he is maintaining. Maybe this is because one no longer recognizes ‘minds’ as entities in their own right, or ‘substances.’ However, selves - the things we refer to by use of ‘I’ - are surely substances, and it does little violence to the intention behind mind/body dualism to interpret it as a dualism of bodies and selves. If the substance dualist’s meaning remains obscure, that is because it can mean several different things to say that selves are not bodies. (shrink)

The question I hope to answer is brief: What does every speaker of a natural language know? My answer is briefer still: Nothing, or at least nothing interesting. Explaining the question, and making the answer plausible, is a longer job.

Leibniz often refers to the Principle of Sufficient Reason (PSR) as something like a first principle. In some texts, however, he attempts to give positive arguments in its favor. I examine two such arguments, and find them wanting. The first argument has two defects. First, it is question-begging; and second, when the question-begging step is excised, the principle one can in fact derive is highly counter-intuitive. The second argument is valid, but has the defect of only reaching a nearly trivial (...) conclusion. (shrink)

After reviewing Kant’s well-known criticisms of the traditional proofs of God’s existence and his preferred moral argument, this paper presents a detailedanalysis of a densely-packed theistic argument in Religion within the Bounds of Bare Reason. Humanity’s ultimate moral destiny can be fulfilled only through organized religion, for only by participating in a religious community (or “church”) can we overcome the evil in human nature. Yet we cannot conceive how such a community can even be founded without presupposing God’s existence. Viewing (...) God as the internal moral lawgiver, empowering a community of believers, is Kant’s ultimate rationale for theistic belief. (shrink)

ABSTRACT Imagine that you are given access to an AI chatbot that compellingly mimics the personality and speech of a deceased loved one. If you start having regular interactions with this “thanabot,” could this new relationship be a continuation of the relationship you had with your loved one? And could a relationship with a thanabot preserve or replicate the value of a close human relationship? To the first question, we argue that a relationship with a thanabot cannot be a true (...) continuation of your relationship with a deceased loved one, though it might support one’s continuing bonds with the dead. To the second question, we argue that, in and of themselves, relationships with thanabots cannot benefit us as much as rewarding and healthy intimate relationships with other humans, though we explain why it is difficult to make reliable comparative generalizations about the instrumental value of these relationships. (shrink)

Knowledge is closed under implication, according to standard theories. Orthodoxy can allow, though, that apparent counterexamples to closure exist, much as Kripkeans recognize the existence of illusions of possibility which they seek to explain away. Should not everyone, orthodox or not, want to make sense of “intimations of openness”? This paper compares two styles of explanation: evidence that boosts P’s probability need not boost that of its consequence Q; evidence bearing on P’s subject matter may not bear on the subject (...) matter of Q. (shrink)

This book represents a major new statement on the issue of property rights. It argues for the justification of some rights of private property while showing why unequal distributions of private property are indefensible. Three features of the book are especially salient: it offers a challenging new pluralist theory of justification; the argument integrates perceptive analyses of the great classical theorists Aristotle, Locke, Hegel and Marx with a discussion of contemporary philosophers such as Nozick and Rawls; and the author moves (...) with assurance among philosophy, law and economics to present a very broad, interdisciplinary study. (shrink)

The common assumption that the Transcendental Deduction aims to refute scepticism often leads interpreters to conclude that it fails and even that Kant is confused about what it is supposed to achieve. By examining what Kant himself says concerning the Deductions' relation to scepticism, this article seeks to determine what sort of scepticism he has in view and how he responds to it. It concludes that the Deduction aims neither to refute Cartesian, outer- world scepticism nor to refute Humean, empiricist (...) scepticism, and it outlines an alternative conception of the Deduction's task, as one of reconciling apparently conflicting claims of reason. (shrink)

Robust Realists think that there are irreducible, non-natural, and mind-independent moral properties. Quasi-Realists and Relaxed Realists think the same, but interpret these commitments differently. Robust Realists interpret them as metaphysical commitments, to be defended by metaphysical argument. Quasi-Realists and Relaxed Realists say that they can only be interpreted as moral commitments. These theories thus pose a serious threat to Robust Realism, for they apparently undermine the very possibility of articulating the robust metaphysical commitments of this theory. I clarify and respond (...) to this threat, showing that there is in fact space to develop and defend a robust moral ontology. (shrink)

This paper argues that calls for neurorights propose an overcomplicated approach. It does this through analysis of ‘rights’ using the influential framework provided by Wesley Hohfeld, whose analytic jurisprudence is still well regarded in its clarificatory approach to discussions of rights. Having disentangled some unclarities in talk about rights, the paper proposes the idea of ‘novel human rights’ is not appropriate for what is deemed worth protecting in terms of mental integrity and cognitive liberty. That is best thought of in (...) terms of Hohfeld’s account of ‘right’ as privilege. It goes on to argue that as privileges, legal protections are not well suited to these cases. As such, they cannot be ‘novel human rights’. Instead, protections for mental integrity and cognitive liberty are best accounted for in terms of familiar and established rational and discursive norms. Mental integrity is best thought of as evaluable in terms of familiar rational norms, and cognitive freedom is constrained by appraisals of sense-making. Concerns about how neurotechnologies might pose particular challenges to mental integrity and cognitive liberty are best protected through careful use of existing legislation on data protection, not novel rights, as it is via data that risks to integrity and liberty are manifested. (shrink)

Given the complexity of teams involved in creating AI-based systems, how can we understand who should be held accountable when they fail? This paper reports findings about accountable AI from 26 interviews conducted with stakeholders in AI drawn from the fields of AI research, law, and policy. Participants described the challenges presented by the distributed nature of how AI systems are designed, developed, deployed, and regulated. This distribution of agency, alongside existing mechanisms of accountability, responsibility, and liability, creates barriers for (...) effective accountable design. As agency is distributed across the socio-technical landscape of an AI system, users without deep knowledge of the operation of these systems become disempowered, unable to challenge or contest when it impacts their lives. In this context, accountability becomes a matter of building systems that can be challenged, interrogated, and, most importantly, adjusted in use to accommodate counter-intuitive results and unpredictable impacts. Thus, accountable system design can work to reconfigure socio-technical landscapes to protect the users of AI and to prevent unjust apportionment of risk. (shrink)

Although Kant had a high regard for Jesus as a moral teacher, interpreters typically assume that his philosophy disallows belief in Jesus as God. Those who regard Kant as a moral reductionist are especially likely to offer a negative construal of the densely-argued subsection of his 1793 Religion that relates directly to this issue. The recent “affirmative” trend in Kant-scholarship provides the basis for an alternative reading. First, theologians must regard Jesus as human so that belief in Jesus can empower (...) believers to become good. Second, theologians may refer to Jesus as divine by identifying his disposition as exemplifying the “archetype of perfect humanity.” Third, Judeo-Christian history poses an empirical problem that theologians can solve by interpreting Jesus’s divinity according to the schematism of analogy. While this does not constitute a robust (identifiably Christian) doctrine of Jesus’s divinity, it does provide clear guidelines for formulating such a tenet of historical faith. (shrink)

Some philosophers contend that the past must be finite in duration, because otherwise reaching the present would have involved the sequential occurrence of an actual infinity of events, which they regard as impossible. I recently developed a new objection to this finitist argument, to which Andrew Ter Ern Loke and Travis Dumsday have replied. Here I respond to the three main points raised in their replies.

According to Quine, the linguist qua grammarian does not know what he is talking about. The goal of this essay is to tell him. My aim is to provide an account of what the grammarian is saying of an expression when he says it is grammatical, or a noun phrase, or ambiguous, or the subject of a certain sentence. More generally, I want to give an account of the nature of a generative grammatical theory of a language – of the (...) data for such a theory, the relation between the theory and the data, and the relation between the theory and a speaker of the language. (shrink)

This paper explains how the notion of justification transmission can be used to ground a notion of knowledge transmission. It then explains how transmission theories can characterise schoolteacher cases, which have prominently been presented as counterexamples to transmission theories.

The Carnegie Council's work “is rooted in the premise that the incorporation of ethical concerns into discussions of international affairs will yield more effective policies both in the United States and abroad.” In honor of the Council's centenary, we have been asked to present our views on the ethical and policy issues posed by climate change, focusing on what people need to know that they probably do not already know, and what should be done. In that spirit, this essay argues (...) that climate change poses a profound ethical challenge, that the ongoing evasion of this challenge produces ineffective policy, and, therefore, that a fundamental paradigm shift is needed. More specifically, I maintain that the climate problem is usually misdiagnosed as a traditional tragedy of the commons, that this obscures two deeper and distinctively ethical challenges, and that we should address these challenges head on, by calling for a global constitutional convention focused on future generations. (shrink)

:Neuroprosthetic speech devices are an emerging technology that can offer the possibility of communication to those who are unable to speak. Patients with ‘locked in syndrome,’ aphasia, or other such pathologies can use covert speech—vividly imagining saying something without actual vocalization—to trigger neural controlled systems capable of synthesizing the speech they would have spoken, but for their impairment.We provide an analysis of the mechanisms and outputs involved in speech mediated by neuroprosthetic devices. This analysis provides a framework for accounting for (...) the ethical significance of accuracy, control, and pragmatic dimensions of prosthesis-mediated speech. We first examine what it means for the output of the device to be accurate, drawing a distinction between technical accuracy on the one hand and semantic accuracy on the other. These are conceptual notions of accuracy.Both technical and semantic accuracy of the device will be necessary for the user to have sufficient control over the device. Sufficient control is an ethical consideration: we place high value on being able to express ourselves when we want and how we want. Sufficient control of a neural speech prosthesis requires that a speaker can reliably use their speech apparatus as they want to, and can expect their speech to authentically represent them. We draw a distinction between two relevant features which bear on the question of whether the user has sufficient control: voluntariness of the speech and the authenticity of the speech. These can come apart: the user might involuntarily produce an authentic output or might voluntarily produce an inauthentic output. Finally, we consider the role of the interlocutor in interpreting the content and purpose of the communication.These three ethical dimensions raise philosophical questions about the nature of speech, the level of control required for communicative accuracy, and the nature of ‘accuracy’ with respect to both natural and prosthesis-mediated speech. (shrink)

Does A cause B simply if A prevents what would have prevented B? Such a case is known as double prevention: where we have the prevention of a prevention. One theory of causation is that A causes B when B counterfactually depends on A and, as there is such a dependence, proponents of the view must rule that double prevention is causation.<br><br>However, if double prevention is causation, it means that causation can be an extrinsic matter, that the cause and effect (...) need not be connected by a continuous chain of events, that there can be causation by absence, and that there can be causation at a distance. All of these implications jar with strong intuitions we have about the nature of causation. There is, on the other hand, a theory of causation based on an ontology of real dispositions, where causation involves the passing around of powers. This theory in contrast entails that double prevention is not causation and, on this issue, it can claim a victory over the counterfactual dependence account. (shrink)