Rasmussen (1993) argues that, because electron microscopists did not use robustness and would not have been warranted in using it as a criterion for the reality or the artifactuality of mesosomes, the bacterial mesosome serves as a test case for robustness that it fails. I respond by arguing that a more complete reading of the research literature on the mesosome shows that ultimately the more robust body of data did not support the mesosome and that electron microscopists used and were (...) warranted in using robustness as a criterion for the artifactuality of mesosomes. (shrink)

Sylvia Berryman offers a fresh understanding of Aristotle's ethical theory, challenging the common belief that he aimed to give it a biological foundation in human nature. Berryman reinterprets Aristotle's views as a 'middle way' between the metaphysical grounding offered by Platonists and sceptical or subjectivist alternatives.

Childhood overweight and obesity, especially among migrant children, are current health problems in several European countries. In the present study the prevalence of overweight and obesity among migrant children from Turkey and the former Yugoslavia was documented and compared with that of Austrian children in Vienna. Anthropometric data from 1786 children were collected at the ages of 6, 10 and 15 years. Body mass was estimated by means of the body mass index and percentile curves were used to determine weight (...) status. The prevalence of overweight and obesity was found to be significantly higher among migrant children. Children and adolescents from the former Yugoslavia and Turkish girls exhibited especially high rates of overweight and obesity. Biosocial and cultural factors are discussed as causes of these observations. (shrink)

Traditional approaches to theory structure and theory change in science do not fare well when confronted with the practice of certain fields of science. We offer an account of contemporary practice in molecular biology designed to address two questions: Is theory change in this area of science gradual or saltatory? What is the relation between molecular biology and the fields of traditional biology? Our main focus is a recent episode in molecular biology, the discovery of enzymatic RNA. We argue that (...) our reconstruction of this episode shows that traditional approaches to theory structure and theory change need considerable refinement if they are to be defended as generally applicable. 1This paper emerged from discussions between us, and we are both equally responsible for its errors. We would like to thank Yvonne Paterson for helpful comments. (shrink)

Sylvia Walsh explores Kierkegaard's understanding of Christianity and the existential mode of thinking theologically appropriate to it in the context of the ...

Noradrenergic pathways are involved in mediating the central and peripheral effects of physiological arousal. The aim of the present study was to investigate the role of noradrenergic transmission in moral decision-making. We studied the effects in healthy volunteers of propranolol (a noradrenergic beta-adrenoceptor antagonist) on moral judgement in a set of moral dilemmas pitting utilitarian outcomes (e.g., saving five lives) against highly aversive harmful actions (e.g., killing an innocent person) in a double-blind, placebo-controlled, parallel group design. Propranolol (40 mg orally) (...) significantly reduced heart rate, but had no effect on self-reported mood. Importantly, propranolol made participants more likely to judge harmful actions as morally unacceptable, but only in dilemmas where harms were ‘up close and personal’. In addition, longer response times for such personal dilemmas were only found for the placebo group. Finally, judgments in personal dilemmas by the propranolol group were more decisive. These findings indicate that noradrenergic pathways play a role in responses to moral dilemmas, in line with recent work implicating emotion in moral decision-making. However, contrary to current theorising, these findings also suggest that aversion to harming is not driven by emotional arousal. Our findings are also of significant practical interest given that propranolol is a widely used drug in different settings, and is currently being considered as a potential treatment for post-traumatic stress disorder in military and rescue service personnel. (shrink)

It has long been thought that the ancient Greeks did not take mechanics seriously as part of the workings of nature, and that therefore their natural philosophy was both primitive and marginal. In this book Sylvia Berryman challenges that assumption, arguing that the idea that the world works 'like a machine' can be found in ancient Greek thought, predating the early modern philosophy with which it is most closely associated. Her discussion ranges over topics including balancing and equilibrium, lifting (...) water, sphere-making and models of the heavens, and ancient Greek pneumatic theory, with detailed analysis of thinkers such as Aristotle, Archimedes, and Hero of Alexandria. Her book shows scholars of ancient Greek philosophy why it is necessary to pay attention to mechanics, and shows historians of science why the differences between ancient and modern reactions to mechanics are not as great as was generally thought. (shrink)

_Living Poetically_ is the first book to focus primarily on Kierkegaard's existential aesthetics as opposed to traditional aesthetic features of his writings such as the use of pseudonyms, literary techniques and figures, and literary criticism. _Living Poetically_ traces the development of the concept of the poetic in Kierkegaard's writings as that concept is worked out in an ethical-religious perspective in contrast to the aesthetics of early German romanticism and Hegelian idealism. Sylvia Walsh seeks to elucidate what it means, in (...) Kierkegaard's view, to be an authentic poet in the form of a poetic writer and to clarify his own role as a Christian poet and writer as he understood it. Walsh shows that, in spite of strong criticisms made of the poetic in some of his writings, Kierkegaard maintained a fundamentally positive understanding of the poetic as an essential ingredient in ethical and religious forms of life. Walsh thus reclaims Kierkegaard as a poetic thinker and writer from those who would interpret him as an ironic practitioner of an aestheticism devoid of and detached from the ethical-religious as well as from those who view him as rejecting the poetic and aesthetic on ethical or religious grounds. Viewing contemporary postmodern feminism and deconstruction as advocating a romantic mode of living poetically, Walsh concludes with a feminist reading of Kierkegaard that affirms both individuality and relatedness, commonalities and differences between the self and others, men and women, for the fashioning of an authentic mode of living poetically in the present age. (shrink)

Der Begriff »Race«, aus den universitären Kulturwissenschaften stammend, will unbewusste Rassifizierungsprozesse beschreiben, die wir unweigerlich vornähmen und denen wir zugleich ausgesetzt seien. Der vorliegende Beitrag will diesen Begriff für Psychoanalyse und Psychotherapie fruchtbar machen. Zwei Fallvignetten illustrieren, welche Fallstricke für Psychoanalytiker und Patienten bereit lägen, wenn »Race« in Übertragung und Gegenübertragung verleugnet werden müsse. Tauchen negativ konnotierte »racial« Phantasien auf, könne die Angst, rassistisch zu denken oder zu agieren, zum Stillstand und sogar Scheitern einer Behandlung führen. Da rassifizierte Projektionen nach (...) Ansicht der Autorin unvermeidbar seien, sieht sie die Entstehung des Gefühls einer »racial Melancholia« als Möglichkeit, dem drohenden Stillstand entgegenzuwirken. (shrink)

I respond to H. M. Collins's claim (1985, 1990, 1993) that experimental inquiry cannot be objective because the only criterium experimentalists have for determining whether a technique is "working" is the production of "correct" (i.e., the expected) data. Collins claims that the "experimenters' regress," the name he gives to this data-technique circle, cannot be broken using the resources of experiment alone. I argue that the data-technique circle, can be broken even though any interpretation of the raw data produced by techniques (...) is theory-dependent. However, it is possible to break this circle by eliminating dependence on even those theoretical presuppositions that are shared by an entire scientific community through the use of multiple independently theory-dependent techniques to produce robust bodies of data. Moreover, I argue, that it is the production of robust bodies of data that convinces experimentalists of the objectivity of their data interpretations. (shrink)

Neoclassical and Austrian/evolutionary economic paradigms have different implications for integrating corporate social responsibility (corporate citizenship) and competitive strategy. porter's "Five Forces" model implicitly rests on neoclassical theory of the firm and is not easily reconciled with corporate social responsibility. Resource-based models of competitive strategy do not explicitly embrace a particular economic paradigm, but to the extent their conceptualization rests on neoclassical assumptions such as imperfect factor markets and profits as rents, these models also imply a trade-off between competitive advantage and (...) corporate social responsibility. Differences in Austrian/evolutionary economic model's assumptions about equilibrium, profits, and other economic concepts allow this paradigm to embrace alternative views of strategy such as the activities or dynamic capabilities views. These alternative views of strategy focus on learning and adaptation; they align more easily with corporate social responsibility. In practice this alignment comes about because social engagement facilitates the learning and adaptation that are a source of competitive advantage. Among the many business arguments for CSR such as improved employee morale/productivity or brand differentiation, this view prioritizes innovation. (shrink)

Scholars across disciplines recognize sport as an institution perpetuating sexism and bias against women in light of its masculine ideals. However, little philosophical research identifies how a masculine environment impacts women’s possibilities in sport. This paper shows that socially structured masculine ideals of athletic excellence impact recognition of women’s athletic achievements while contributing to contexts endangering respect and self-respect. Exploring athletic disrespect reveals connections to more broadly harmful sport practices that include physical and sexual violence. Thus, the practical concern is (...) that sport’s masculine ideals might undermine women’s pursuit of athletic excellence in more harmful ways than previously recognized. (shrink)

A sympathetic examination of the failure of anti-corruption efforts in contemporary Indonesia. Combining ethnographic fieldwork in the city of Kupang with an acute historical sensibility, Sylvia Tidey shows how good governance initiatives paradoxically perpetuate civil service corruption while also facilitating the emergence of new forms of it. Importing critical insights from the anthropology of ethics to the burgeoning anthropology of corruption, Tidey exposes enduring developmentalist fallacies that treat corruption as endemic to non-Western subjects. In practice, it is often indistinguishable (...) from the ethics of care and exchange, as Indonesian civil servants make worthwhile lives for themselves and their families. This book will be a vital text for anthropologists and other social scientists, particularly scholars of global studies, development studies, and Southeast Asia. (shrink)

Arguments in the neuroenhancement debate are sometimes based upon idealistic scenarios involving the assumption of using a drug that has no or negligible side effects. At least it is often implicitly assumed – as technology and scientific knowledge advances - that there soon will be a drug with no or negligible side effects. We will review evidence from neuroscience, complex network research and evolution theory and demonstrate that - at least in terms of psychopharmacological intervention – on the basis of (...) our understanding of brain function it seems inconceivable that there ever will be a drug that has the desired effect without undesirable side effects. We will illustrate this by reference to enhancing edge detection in V2 in monkeys and demonstrate that even for this localised single neuron coded function there would be numerous side effects. Taking the more realistic case of pharmacological enhancement that is inevitably associated with side effects will change consequentialist arguments for neuroenhancement and have implications for the conception of autonomy, specifically in the case of performance enhancement. We conclude that a neuroethics debate that aims to inform policy decisions should take these findings into account. We hope that our article will precipitate more interdisciplinary research in neuroscience and philosophy. (shrink)

The article aims to present, in a comparative analysis between the romanticist value subjectivity and the postmodern one (which for Lyotard is no less “tribute to romanticism”), the metamorphosis of the most reflective, or borderline aesthetic categories-values (the sublime, the ironic, the tragic as a “tragedy of existence” in the sense of Losev; the absurd in its aesthetic interpretation, etc.): how, after the “verticals of the Spirit” have been torn out and in the conditions of “a thousand plateaus”, these values (...) continue to be not just thinkable and possible, but precisely they give legitimacy to the modern aesthetic. This is also the context of interpretation of the question of the end of romanticism, logically intertwined with other discussed ends with an axiological basis—of the complete personality, of art, of “great narratives”…. (shrink)

Dans le silence qui entoure la question du temps et des temporalités dans l’espace oriental, l’ouvrage Les Ottomans et le temps constitue une contribution novatrice et précieuse. On ne peut que regretter qu’il ait fallu attendre près de dix ans pour prendre connaissance des résultats de travaux commencés dès 2003-2004 dans le cadre d’un séminaire de l’École des hautes études en sciences sociales, inscrit dans la continuité du travail fondateur de Louis Bazin sur Les systèmes chronologiques d..

Cet article se penche sur une figure de l’imaginaire collectif, à savoir Mickey Mouse. Cette souris sympathique qui a fait le tour du globe dans les années 1930 est devenue l’animal héraldique du triomphe des économies pulsionnelles et d’une mercantilisation du rêve de bonheur. En partant d’une réflexion sur la contiguïté entre l’activité ludique et l’art de l’animation, l’article tente d’aborder la question de « l’esthétisation de la politique » par le biais du jeu. Une référence constante à la fonction (...) du conte dans le monde enfantin nous permet d’articuler quelques enjeux de ce que W. Benjamin analyse, dans son essai sur L’Œuvre d’art à l’époque de sa reproductibilité technique, sous le terme de « seconde technique ». (shrink)

In the quantum logic approach, Bell inequalities in the sense of Pitowski are related with quasi hidden variables in the sense of Deliyannis. Some properties of hidden variables on effect algebras are discussed.

This article discusses how the concept of a fair finite lottery can best be extended to denumerably infinite lotteries. Techniques and ideas from non-standard analysis are brought to bear on the problem.

Ce texte est l'introduction d'un dossier remarquable de la Revue des mondes musulmans et de la Méditerranée, n° 136, 2014, p. 13-183, entièrement disponible ici. Nous remercions Sylvia Chiffoleau de nous avoir autorisé à le reproduire sur RHUTHMOS. Les contributions de ce numéro se proposent d'explorer quelques-unes des multiples facettes du temps. Lorsqu'on aborde la question du temps, il est convenu de rappeler la difficulté à appréhender celui-ci, en s'appuyant sur le célèbre aphorisme de Saint - Histoire – Nouvel (...) article. (shrink)

Big Data enhances the possibilities for storing personal data extracted from social media and web search on an unprecedented scale. This paper draws on the political economy of information which explains why the online industry fails to self-regulate, resulting in increasingly insidious web-tracking technologies. Content analysis of historical blogs and request for comments on HTTP cookies published by the Internet Engineering Task Force illustrates how cookie technology was introduced in the mid-1990s, amid stark warnings about increased system vulnerabilities and deceptive (...) personal data extractions. In conclusion, online users today are left with few alternatives but to enter into unconscionable contracts about the extraction of their personal data when using the Internet for private purposes. (shrink)

Entrevista realizada durante a conferência proferida por Sylvia Serbin nas atividades do “Congresso Internacional Territorialidade e Saude: desigualdades raciais e sociais em contextos locais e globais”, organizado e coordenado pelo Nucleo de Estudos e Pesquisa em Psicanalise, Identidade, Negritude e Sociedade, ocorrido de 03 a 7 de setembro de 2014, no Centro de Ciências da Saude da Universidade Federal do Recôncavo da Bahia, em Santo Antonio de Jesus/BA.

Background In this study, we examined the ethical implications of Egypt’s new clinical trial law, employing the ethical framework proposed by Emanuel et al. and comparing it to various national and supranational laws. This analysis is crucial as Egypt, considered a high-growth pharmaceutical market, has become an attractive location for clinical trials, offering insights into the ethical implementation of bioethical regulations in a large population country with a robust healthcare infrastructure and predominantly treatment-naïve patients. Methods We conducted a comparative analysis (...) of Egyptian law with regulations from Sweden and France, including the EU Clinical Trials Regulation, considering ethical human subject research criteria, and used a directed approach to qualitative content analysis to examine the laws and regulations. This study involved extensive peer scrutiny, frequent debriefing sessions, and collaboration with legal experts with relevant international legal expertise to ensure rigorous analysis and interpretation of the laws. Results On the rating of the seven different principles (social and scientific values, scientific validity, fair selection of participants, risk-benefit ratio, independent review, informed consent and respect for participants) Egypt, France, and EU regulations had comparable scores. Specific principles (Social Value, Scientific Value, and Fair selection of participants) were challenging to directly identify due to certain regulations embodying 'implicit' principles more than explicitly stated ones. Conclusion The analysis underscores Egypt's alignment with internationally recognized ethical principles, as outlined by Emanuel et al., through its comparison with French, Swedish, and EU regulations, emphasizing the critical need for Egypt to continuously refine its ethical regulations to safeguard participant protection and research integrity. Key issues identified include the necessity to clarify and standardize the concept of social value in research, alongside concerns regarding the expertise and impartiality of ethical review boards, pointing towards a broader agenda for enhancing research ethics in Egypt and beyond. (shrink)

This paper presents a relational account of autonomy showing that a technological imperative impedes autonomy through undermining women’s capacity to resist use of technology in the context of labor and birth. A technological imperative encourages dependence on technology for reassurance whenever possible through creating a (i) separation of maternal and fetal interests; and (ii) perceived need to use technology whenever possible. In response I offer an account of how women might promote autonomy through cultivating self-trust and self-confidence. Autonomy is not (...) simply a matter of choosing freely and acting on our choices, it is also a matter of possessing the ability to resist social contexts undermining choice and action. An important implication of this view is that respecting autonomy requires more than simply respecting persons’ ability to make and act on choices. Respecting patient autonomy requires a recognition of patients’ need to resist factors impeding autonomy and support for that resistance. (shrink)

The pseudonymous works Kierkegaard wrote during the period 1843–46 have been responsible for establishing his reputation as an important philosophical thinker, but for Kierkegaard himself, they were merely preparatory for what he saw as the primary task of his authorship: to elucidate the meaning of what it is to live as a Christian and thus to show his readers how they could become truly Christian. The more overtly religious and specifically Christian works Kierkegaard produced in the period 1847–51 were devoted (...) to this task. In this book Sylvia Walsh focuses on the writings of this later period and locates the key to Kierkegaard’s understanding of Christianity in the “inverse dialectic” that is involved in “living Christianly.” In the book’s four main chapters, Walsh examines in detail how this inverse dialectic operates in the complementary relationship of the negative qualifications of Christian existence—sin, the possibility of offense, self-denial, and suffering—to the positive qualifications—faith, forgiveness, new life/love/hope, and joy and consolation. It was Kierkegaard’s aim, she argues, “to bring the negative qualifications, which he believed had been virtually eliminated in Christendom, once again into view, to provide them with conceptual clarity, and to show their essential relation to, and necessity in, securing a correct understanding and expression of the positive qualifications of Christian existence.”. (shrink)

The Snow White problem is introduced to demonstrate how learning something of which one could not have learnt the opposite (due to observer selection bias) can change an agent’s probability assignment. This helps us to analyse the Sleeping Beauty problem, which is deconstructed as a combinatorial engine and a subjective wrapper. The combinatorial engine of the problem is analogous to Bertrand’s boxes paradox and can be solved with standard probability theory. The subjective wrapper is clarified using the Snow White problem. (...) Sample spaces for all three problems are presented. The conclusion is that subjectivity plays no irreducible role in solving the Sleeping Beauty problem and that no reference to centered worlds is required to provide the answer. (shrink)

Cancer treatment decisions should be based on all available evidence. But this evidence is complex and varied: it includes not only the patient’s symptoms and expert knowledge of the relevant causal processes, but also clinical databases relating to past patients, databases of observations made at the molecular level, and evidence encapsulated in scientific papers and medical informatics systems. Objective Bayesian nets offer a principled path to knowledge integration, and we show in this chapter how they can be applied to integrate (...) various kinds of evidence in the cancer domain. This is important from the systems biology perspective, which needs to integrate data that concern different levels of analysis, and is also important from the point of view of medical informatics. (shrink)

What does it mean to live in asylum? How is health affected by the living conditions in camps and camp-like facilities? And what is unjust about it? Combining philosophical analysis with exploring methods of qualitative research, namely reflexive thematic analysis, this work identifies global pat-terns of the situation in and the space of asylum. Using results of existing empirical public health research as well as a phenomenological approach and the concept of forms of life developed in Social philosophy by Rahel (...) Jaeggi, the interdisciplinary methodology allows to look at the impact of every-day-life conditions, the multifaceted intersectional and ambiguous patterns of in-/exclusion as well as the global political forces shaping asylum. Asylum viewed from - as close as possible - the perspective of having to live in it as a forced form of life and a place shaped by power-asymmetries, control and dependency proves to be an unlivable non-place. (shrink)

In my quest for Aurai in Greek art, I have been surprised by the haste of commentators to label each and every running woman as a Nereid. Surely it should depend on the evidence. I begin with two Attic pyxides in the Fitzwilliam Museum, Cambridge. The first GR 1. 1933 was given and published by Miss Lamb in CVA Cambridge ii pl. 26. In Beazley, ARV 297, this vase was said to be in the Manner of Douris. In ARV 451 (...) this vase has lost its own reference and acquired that of GR 10. 1934.‘Nereids’ is an inadequate description of either vase; for both include different sexes.The pyxis 1. 1933 is not in good condition. The central figure is surely not the male, as Miss Lamb says, but a running woman taking up twice as much room as anyone else. She holds one dolphin and has lost another, so she must be the heroine Thetis. On one side of her stands a man with a dark beard, but he holds an old man's crooked stick, so he must be Nereus in spite of his dark beard: and a frightened Nereid rushes by him to the left: on a third side a stationary woman has just frightened a woman with a sceptre off her chair; the sceptre holder must be Doris. Here then we have a Peleus and Thetis scene, but there is no room for Peleus. (shrink)

A continuación se plantean las bases epistemológicas de un modelo que busca explicar y guiar el tratamiento informativo de los conflictos en la prensa. El aporte teórico parte del discurso; desde el lenguaje y hacia el lenguaje. Se recomienda el estudio de las estrategias lingüístico-comunicativas q..

Difficile à lire, connu de réputation pour ses objections aux Méditations de Descartes, sa réhabilitation d'Épicure et des atomes, voire le caractère ambigu de ses relations avec les "libertins", Pierre Gassendi est un personnage un peu flou dans notre galerie de portraits imaginaire. Il fut cependant un auteur important, lu, connu, approuvé ou critiqué dans toute l'Europe, surtout par les savants qui voulaient fonder efficacement leur physique moderne sans renier pour autant les acquis des anciens. Les études réunies ici ont (...) cherché comme la trace et le reflet de l'œuvre de Gassendi dans les écrits d'autres auteurs qui ont vécu de son temps et jusqu'à la fin des Lumières - non seulement en France -, mais aussi en Angleterre (comme Walter Charleton, John Locke, David Hume ou Robert Boyle), en Hollande (professeurs d'Université), en Allemagne (Leibniz), en Pologne (Sociniens et "libertins"), en Italie du Nord (comme le jésuite milanais Thommaso Ceva), en Italie du Sud (comme le fondateur de l'Accademia degli Investiganti Tommaso Cornelio ou Giambattista Vico), en Espagne enfin (comme le médecin Martínez). Aujourd'hui encore Gassendi fait des adeptes parmi ceux que séduisent les chemins non battus de l'effort gratuit et de l'érudition austère, ceux que ravit absolument une certaine esthétique baroque de l'esprit pur. (shrink)