BackgroundDepression and anxiety create a large health burden and increase the risk of premature mortality. Mental health screening is vital, but more sophisticated screening and monitoring methods are needed. The Ellipsis Health App addresses this need by using semantic information from recorded speech to screen for depression and anxiety.ObjectivesThe primary aim of this study is to determine the feasibility of collecting weekly voice samples for mental health screening. Additionally, we aim to demonstrate portability and improved performance of Ellipsis’ machine learning (...) models for patients of various ages.MethodsStudy participants were current patients at Desert Oasis Healthcare, mean age 63 years. Two non-randomized cohorts participated: one with a documented history of depression within 24 months prior to the study, and the other without depression. Participants recorded 5-min voice samples weekly for 6 weeks via the Ellipsis Health App. They also completed PHQ-8 and GAD-7 questionnaires to assess for depression and anxiety, respectively.ResultsProtocol completion rate was 61% for both groups. Use beyond protocol was 27% for Group Positive and 9% for Group Negative. The Ellipsis Health App showed an AUC of 0.82 for the combined groups when compared to the PHQ-8 and GAD-7 with a threshold score of 10. Performance was high for senior participants as well as younger age ranges. Additionally, many participants spoke longer than the required 5 min.ConclusionThe Ellipsis Health App demonstrated feasibility in using voice recordings to screen for depression and anxiety among various age groups and the machine learning models using Transformer methodology maintain performance and improve over LSTM methodology when applied to the study population. (shrink)

Monomodal logic has exactly two maximally normal logics, which are also the only quasi-normal logics that are Post complete, and they are complete for validity in Kripke frames. Here we show that addition of a propositional constant to monomodal logic allows the construction of continuum many maximally normal logics that are not valid in any Kripke frame, or even in any complete modal algebra. We also construct continuum many quasi-normal Post complete logics that are not normal. The set of extensions (...) of S4.3 is radically altered by the addition of a constant: we use it to construct continuum many such normal extensions of S4.3, and continuum many non-normal ones, none of which have the finite model property. But for logics with weakly transitive frames there are only eight maximally normal ones, of which five extend K4 and three extend S4. (shrink)

The article contains a critical analysis of two conceptions of “the nature of things”, as found in publications of West German philosophers of law: G. Radbruch and W. Maihoffer. In the first stage of the evolution of his thought Radbruch spoke of the “influence of the matter on the legal idea”. The function of “the nature of things” is identified by Radbruch with resistance by social reality to the implantation of the legal idea. In the next stage of his views (...) Radbruch conceives of the nature of things as an objective sense of a certain social relationship, perceived from the point of view of a certain value. Now the nature of things serves as a bridge between the real world and the world of values. The nature of things has a minor role according to Radbruch, in legal thought. He emphatically opposes recognizing it as a source of law. (shrink)

Knobe contends that in making judgments about a wide range of matters, moral considerations and scientific considerations are and thus that We argue that his own account of the mechanism underlying these judgments does not support this radical conclusion.

In this interview, Tomasz Zarębski speaks with Allan Janik, co-author of _Wittgenstein’s Vienna_ (1973, with Stephen Toulmin), on the occasion of the 50 th anniversary of the publication of this pathbreaking book. The conversation concerns the circumstances, motivations and reasons for his undertaking the work on the book, as well as its reception and place in Wittgenstein scholarship. A large part of the discussion refers to his perspective of Wittgenstein, Toulmin’s philosophical writings, and Janik’s own vision of philosophy. The (...) interview took place in Innsbruck on 23 rd and 25 th August 2023. (shrink)

Reclamation of a slur involves the creation of a new, positively-valenced meaning that gradually replaces the old pejorative meaning. This means that at a critical stage, the slur is ambiguous. It has been claimed that this ambiguity is polysemy. However, it is far from clear whether the view can explain why the introduction of the new meaning forces the old one out of existence. I argue that this datapoint can be explained by invoking the mechanism of homonymic conflict, and, therefore, (...) that the ambiguity involved in reclamation is homonymy. One generalization that follows from my account is that conventionalized verbal irony, unlike conventionalized metonymy and metaphor, begets homonymy. Along the way, I criticize the standard ways of drawing the distinction between polysemy and homonymy in terms of semantic and etymological relatedness. If the notions of polysemy and homonymy are to be invoked in explanations, they should be understood in terms of how meanings are stored in the mental lexicon. My account also provides an elegant way of conceptualizing the difference between two types of conceptual engineering, namely reclamation and amelioration. (shrink)

To analyze potential negative consequences of adopting generative AI solutions in the digital afterlife industry (DAI), in this paper we present three speculative design scenarios for AI-enabled simulation of the deceased. We highlight the perspectives of the data donor, data recipient, and service interactant – terms we employ to denote those whose data is used to create ‘deadbots,’ those in possession of the donor’s data after their death, and those who are meant to interact with the end product. We draw (...) on the scenarios to map out several key ethical concerns posed by ‘re-creation services’ and to put forward recommendations on the ethical development of AI systems in this specific area of application. The recommendations, targeted at providers of AI-enabled re-creation services, include suggestions for developing sensitive procedures for retiring deadbots, ensuring meaningful transparency, restricting access to such services to adult users only, and adhering to the principle of mutual consent of both data donors and service interactants. While we suggest practical solutions to the socio-ethical challenges posed by the emergence of re-creation services, we also emphasize the importance of ongoing interdisciplinary research at the intersection of the ethics of AI and the ethics of the DAI. (shrink)

In this commentary paper, we are taking one step further in questioning the central assumptions in the bioethical debates about reproductive technologies. We argue that the very distinction between “person affecting” and “identity affecting” interventions is based on a questionable form of material-origin essentialism. Questioning of this form of essentialist approach to human identity allows treating genome editing and genetic selection as more similar than they are taken to be in the standard approaches. It would also challenge the idea that (...) normative reasons we have in these two types of cases markedly differ in strength. (shrink)

We argue that there are neither scientific nor social reasons to require gathering ethno-racial data, as defined in the US legal regulations if researchers have no prior hypotheses as to how to connect this type of categorisation of human participants of clinical trials with any mechanisms that could explain alleged interracial health differences and guide treatment choice. Although we agree with the normative perspective embedded in the calls for the fair selection of participants for biomedical research, we demonstrate that current (...) attempts to provide and elucidate the criteria for the fair selection of participants, in particular, taking into account ethno-racial categories, overlook important epistemic and normative challenges to implement the results of such race-sorting requirements. We discuss existing arguments for and against gathering ethno-racial statistics for biomedical research and present a new one that refers to the assumption that prediction is epistemically superior to accommodation. We also underline the importance of closer interaction between research ethics and the methodology of biomedicine in the case of population stratifications for medical research, which requires weighing non-epistemic values with methodological constraints. (shrink)

Standard deontic logic (SDL) is defined on the basis of possible world semantics and is a logic of alethic-deontic modalities rather than deontic modalities alone. The interpretation of the concepts of obligation and permission comes down exclusively to the logical value that a sentence adopts for the accessible deontic alternatives. Here, we set forth a different approach, this being a logic which additionally takes into consideration whether sentences stand in relation to the normative system or to the system of values (...) under which we predicate the deontic qualifications. By taking this aspect into account, we arrive at a logical system which preserves laws proper to a deontic logic but where the standard paradoxes of deontic logic do not arise. It is a logic of strictly-deontic modalities DR. (shrink)

My paper builds on the conceptual tools from three interrelated philosophical debates that—as I believe—may help structure important if chaotic discussions about surrogates for living human brains and resolve some practical issues related to regulatory matters. In particular, I refer to the discussions about the “moral precautionary principle” in research ethics (Koplin and Wilkinson 2019); about normative uncertainty in ethics (MacAskill, Bykvist, and Ord 2020), and about the inductive risk problem for animal welfare scientists (Birch 2018). I elucidate upon the (...) possible meanings of the phrase “a too good human brain surrogate” used by Henry T. Greely (2021), and I demonstrate that the evaluation of the practical and regulatory implications of the “goodness” of such surrogates created for research purposes should be sensitive to the possible consequences of two types of errors: the under-attribution and over-attribution of moral status to such beings. Many authors writing about this topic (including Greely 2021, but see also, e.g., Koplin and Savulescu 2019) concentrate only on the first type of error, neglecting the negative consequences of the second type, i.e., over-attribution. (shrink)

Consider how we evaluate how normal an object is. On the dual-nature hypothesis, a normality evaluation depends on the object’s goodness and frequency. On the single-nature hypothesis, the evaluation depends solely on either frequency or goodness. To assess these hypotheses, I ran four experiments. Study 1 shows that normality evaluations vary with both the goodness and the frequency assessment of the object. Study 2 shows that manipulating the goodness and the frequency dimension changes the normality evaluation. Yet, neither experiment rules (...) out that some people evaluate normality solely based on frequency, and the rest evaluate normality solely based on goodness. Whence two more experiments. Study 3 reveals that when scenarios are contrasted—presented one after another—only frequency matters. But, as study 4 shows, when scenarios are evaluated alone, both frequency and goodness influence normality evaluations in a single person, although the more a person is sensitive to one dimension, the less she’s sensitive to the other. The dual-nature hypothesis seems thus true of uncontrasted applications of the concept of normality, whereas the single-nature hypothesis seems true of contrasted applications. (shrink)

Incorporating normality ascriptions into counterfactual theories of causation was supposed to handle isomorphs. It doesn’t—conjoining isomorphs can produce cases that such ascriptions cannot resolve.

In this article, I present a new interpretation of the pro-life view on the status of early human embryos. In my understanding, this position is based not on presumptions about the ontological status of embryos and their developmental capabilities but on the specific criteria of rational decisions under uncertainty and on a cautious response to the ambiguous status of embryos. This view, which uses the decision theory model of moral reasoning, promises to reconcile the uncertainty about the ontological status of (...) embryos with the certainty about normative obligations. I will demonstrate that my interpretation of the pro-life view, although seeming to be stronger than the standard one, has limited scope and cannot be used to limit destructive research on human embryos. (shrink)

Here, we discuss historical, philosophical and technical problems associated with relating logic and relating semantics. To do so, we proceed in three steps. First, Section 1 is devoted to providing an introduction to both relating logic and relating semantics. Second, we address the history of relating semantics and some of the main research directions and their philosophical applications. Third, we discuss some technical problems related to relating semantics, particularly whether the direct incorporation of the relation into the language of relating (...) logic is needed. The starting point for our considerations presented here is the 1st Workshop On Relating Logic and the selected papers for this issue. (shrink)

According to psychological research, people are more eager to help identified individuals than unidentified ones. This phenomenon significantly influences many important decisions, both individual and public, regarding, for example, vaccinations or the distribution of healthcare resources. This paper aims at presenting definitions of various levels of identifiability as well as a critical analysis of the main philosophical arguments regarding the normative significance of the identifiability effect, which refer to: (1) ex ante contractualism; (2) fair distribution of chances and risks; (3) (...) anti-aggregationist principles that recommend the distribution of bad effects and the concentration of good ones. I will show that these arguments, although connected with interesting philosophical problems regarding e.g. counterfactuals, aggregation, or probability, are unconvincing. (shrink)

We show that truth conditions for counterfactuals need not always be given in terms of a vague notion of similarity. To this end, we single out the important class of historical counterfactuals and give formally rigorous truth conditions for these counterfactuals, employing a partial ordering relation called "comparative closeness" that is defined in the framework of branching space-times. Among other applications, we provide a detailed analysis of counterfactuals uttered in the context of lost bets. In an appendix we compare our (...) theory with the branching space-times based reading of counterfactuals recently proposed by Belnap. (shrink)

The aim of this paper is to reconstruct and correct one argument in support of the symmetrization postulate in quantum mechanics. I identify the central premise of the argument as a thesis specifying a particular ontic property of quantum superpositions. The precise form of this thesis depends on some underlying assumptions of a metaphysical character. I compare the exchange degeneracy argument with alternative formal arguments for the symmetrization postulate, and I discuss the role and meaning of labels in the symmetric/antisymmetric (...) representations of the states of many particles. (shrink)

In this paper, I argue that enactivism and computationalism—two seemingly incompatible research traditions in modern cognitive science—can be fruitfully reconciled under the framework of the free energy principle. FEP holds that cognitive systems encode generative models of their niches and cognition can be understood in terms of minimizing the free energy of these models. There are two philosophical interpretations of this picture. A computationalist will argue that as FEP claims that Bayesian inference underpins both perception and action, it entails a (...) concept of cognition as a computational process. An enactivist, on the other hand, will point out that FEP explains cognitive systems as constantly self-organizing to non-equilibrium steady-state. My claim is that these two interpretations are both true at the same time and that they enlighten each other. (shrink)

The paper investigates, in the framework of branching space–times, whether an infinite EPR-like correlation which does not involve finite EPR-like correlations is possible.

Konserwatywni przeciwnicy prowadzenia badań naukowych na ludzkich embrionach argumentują, że od momentu poczęcia mają one status moralny równy statusowi ludzi dorosłych: zarodki mają takie samo prawo do życia jak dorośli. W artykule przedstawiam oryginalną argumentację za tym stanowiskiem, której źródła można znaleźć w XVII-wiecznej teologii moralnej i współczesnej teorii decyzji. Argumentacja ta nie odwołuje się do statusu ontologicznego embrionów, ale do pewnego typu rozumowania praktycznego na temat tego, co należy robić w rozmaitych sytuacjach niepewności. Na pierwszy rzut oka wydaje się (...) ona wzmacniać stanowisko konserwatywne, ponieważ nie zależy od kontrowersyjnych metafizycznych założeń na temat statusu zarodków czy kwestii ich potencjalności. W artykule pokażę jednak, że argumentacja ta obarczona jest poważnymi wadami, które sprawiają, że nie da się jej zastosować do uzasadnienia sprzeciwu wobec moralnej czy prawnej dopuszczalności np. badań na zarodkowych komórkach macierzystych. (shrink)

The paper extends the framework of outcomes in branching space-time (Kowalski and Placek [1999]) by assigning probabilities to outcomes of events, where these probabilities are interpreted either epistemically or as weighted possibilities. In resulting models I define the notion of common cause of correlated outcomes of a single event, and investigate which setups allow for the introduction of common causes. It turns out that a deterministic common cause can always be introduced, but (surprisingly) only special setups permit the introduction of (...) truly stochastic common causes. I analyse next the Bell-Aspect experiment and derive the Bell-CH inequalities. I observe that we postulate there not a common cause for outcomes of a single event but rather a common common cause that accounts for outcomes of many events, where 'events' mean 'measurements with (different) directions of polarization'. Since the inequalities are violated, I claim that no causal story can be told about the Bell correlations, where causality is subliminal and restricted by screening-off condition. Similarly, given certain intuitive principles, no deterministic story can be told about these correlations. (shrink)

The development of innovative biomedical technologies that use gene editing tools opens up new possibilities in the treatment of rare diseases, as well as diseases that were not previously treated...