Historically, scientific and engineering expertise has been key in shaping research and innovation policies, with benefits presumed to accrue to society more broadly over time. But there is persistent and growing concern about whether and how ethical and societal values are integrated into R&I policies and governance, as we confront public disbelief in science and political suspicion toward evidence-based policy-making. Erosion of such a social contract with science limits the ability of democratic societies to deal with challenges presented by new, (...) disruptive technologies, such as synthetic biology, nanotechnology, genetic engineering, automation and robotics, and artificial intelligence. Many policy efforts have emerged in response to such concerns, one prominent example being Europe's Eighth Framework Programme, Horizon 2020, whose focus on “Responsible Research and Innovation” provides a case study for the translation of such normative perspectives into concrete policy action and implementation. Our analysis of this H2020 RRI approach suggests a lack of consistent integration of elements such as ethics, open access, open innovation, and public engagement. On the basis of our evaluation, we suggest possible pathways for strengthening efforts to deliver R&I policies that deepen mutually beneficial science and society relationships. (shrink)

The aim of this paper is to question the significance of Derrida's deconstruction of the concepts of subject and history. While ‘postmodernity’ tends to be characterized by philosophical critique as the ‘liquidation of the subject’ or the ‘end of history’, I attempt to show that Derrida's deconstruction of ‘subjectivity’ and ‘historicity’ is not an elimination or destruction of these concepts, but an attempt to transform them in order to free them from their metaphysical-teleological presuppositions. This paper argues that this transformation, (...) which begins in Derrida's and continues in Stiegler's texts, leads to the notions of ‘psycho-social individuation’ and ‘doubly epokhal redoubling’. I maintain that such notions ‘supplement’ the metaphysical concepts of subject and history by forcing a reconsideration of the technical conditions of psychic individuation and the technological conditions of ‘epochality’. (shrink)

This paper assesses great apes’ abilities for pantomime and action imitation, two communicative abilities proposed as key contributors to language evolution. Modern great apes, the only surviving nonhuman hominids, are important living models of the communicative platform upon which language evolved. This assessment is based on 62 great ape pantomimes identified via data mining plus published reports of great ape action imitation. Most pantomimes were simple, imperative, and scaffolded by partners’ relationship and scripts; some resemble declaratives, some were sequences of (...) several inter-related elements. Imitation research consistently shows great apes perform action imitation at low fidelity, but also that action imitation may not represent a distinct process or function. Discussion focuses on how findings may advance reconstruction of the evolution of language, including what great apes may contribute to understanding ‘primitive’ forms of pantomime and imitation and how to improve their study. (shrink)

Translational research is a buzzword which dominates discussions about the quality, the utilization, and the benefits of medical research. Yet, although translational research has become a prominent topic, no commonly agreed definition of this terminology exists. Instead, experts from different contexts such as biomedical research, clinical practice or nursing discuss translational research in multiple ways depending on how they define the problem that translational research is supposed to be the solution to. In this paper, we do not seek to find (...) a ‘correct’ definition of translational research, but instead ask how actors using this terminology for describing their own research make sense of it. To do so, we asked three questions: Which actors are engaged in the debate about translational research? What kind of different meanings of translational research exist? And, which actors refer to which meaning of translational research when using the term? In answering these questions, we highlight the role this terminology plays in defining what medical science is about today. (shrink)

PstS and DING proteins are members of a superfamily of secreted, high‐affinity phosphate‐binding proteins. Whereas microbial PstS have a well‐defined role in phosphate ABC transporters, the physiological function of DING proteins, named after their DINGGG N termini, still needs to be determined. PstS and DING proteins co‐exist in some Pseudomonas strains, to which they confer a highly adhesive and virulent phenotype. More than 30 DING proteins have now been purified, mostly from eukaryotes. They are often associated with infections or with (...) dysregulation of cell proliferation. Consequently, eukaryotic DING proteins could also be involved in cell–cell communication or adherence. The ubiquitous presence in eukaryotes of proteins structurally and functionally related to bacterial virulence factors is intriguing, as is the absence of eukaryotic genes encoding DING proteins in databases. DING proteins in eukaryotes could originate from unidentified commensal or symbiotic bacteria and could contribute to essential functions. Alternatively, DING proteins could be encoded by eukaryotic genes sharing special features that prevent their cloning. Both hypotheses are discussed. (shrink)

The contemporary global language “extinction crisis” has been analyzed by several influential linguists using concepts from ecology. In this article we study different reaction-diffusion models to explain the dynamics of language competition. We are mainly interested in situations where one language has a status advantage compared with the other. We consider previous applications of competition models from ecology, with particular attention to the implications of the “carrying capacity” term in such models. We derive existence as well as stability conditions for (...) the equilibria of the models considered, and show that depending on environmental conditions both situations—coexistence of competing languages or extinction of the less advantageous language—are possible. (shrink)

Reading difficulties that are not addressed at the primary level continue to exist at the secondary level with serious consequences. Thus, it is important to provide struggling students with specific reading support. In particular, many students with learning disabilities and emotional behavioral disorders demonstrate reading obstacles and are at risk for motivation loss. A multiple baseline design was used to evaluate the effects of a motivational reading racetrack as peer-tutoring on the word reading skills of secondary students with LD with (...) and without EBD. The intervention was conducted through 4–5 baseline and 16–18 reading units three times a week for 15 min over 8 weeks. The results showed positive effects indicating a highly effective treatment. In addition, follow-up results were also promising. Our findings indicate that this multicomponent intervention has a positive effect on the word fluidity of low-achieving students in secondary education with LD and/or EBD. (shrink)

ABSTRACTIn this paper, I argue that, contrary to popular opinion, there is good reason to think that the qualities that make people good reasoners also make them better off. I will focus specifically on epistemic virtue: roughly, the kind of character in virtue of which one is excellently oriented towards epistemic goods. I propose that epistemic virtue is importantly implicated in the realization of some of the goods that are widely believed to be instrumental to, or even constitutive of, well-being. (...) Here I focus on one such good: friendship. (shrink)

Claims regarding negative strong reciprocity do indeed rest on experiments lacking established external validity, often without even a small Guala's review should prompt strong reciprocity proponents to extend the real-world validity of their work, exploring the preferences participants bring to experiments. That said, Guala's approach fails to differentiate among group selection approaches and glosses over cross-cultural variability.

This book explores five Platonic dialogues: Lysis, Charmides, Protagoras, Euthydemus, and the Republic. This book uses Socrates’ narrative commentary as its primary interpretive framework. No one has engaged in a sustained attempt to explore the Platonic dialogues from this angle. As a result, it offers a unique contribution to Plato scholarship. The portrait of Socrates that emerges challenges the traditional view of Socrates as an intellectualist and offers a holistic vision of philosophical practice.

In the recent epistemological literature much has been written about the nature of suspending judgement or agnosticism. There has also been a surge of recent interest in the nature of ignorance. But what is the relationship between these two epistemically significant states? Prima facie, both suspension and ignorance seem to involve the lack of a correct answer to a question. And, again prima facie, there may be some intuitive attraction to the idea that when one is ignorant whether p, one (...) ought to suspend judgement whether p. In this paper we will explore a range of different possible normative connections between ignorance and suspension of judgement. We will also discuss how both ignorance and suspension are related to having inconclusive evidence. As we will see, the issues can become quite complex due to the fact that there are different, competing views about the nature of ignorance and also about the nature of suspension. Moreover, there are importantly different kinds of epistemic norms. Our overall aim then will be to systematically chart how these different choices will impact the possible normative connections between ignorance and suspension. (shrink)

Using contemporary insights from feminist critical theory and the literary image of synecdoche, we argue that transdisciplinary knowledge is productive because it “maximizes serendipity.” We draw on student learning experiences in a course on Gender and Science to illustrate how the dichotomous frameworks and part-whole correspondences that are predominant in much disciplinary discourse must be dismantled ifor innovative intellectual work to take place. In such a process, disciplinary presumptions interrogate and unsettle one another to produce novel questions and answers.

During the Interregnum, English natural philosophers and chymists became deeply interested in Pierre Gassendi’s revival of Epicurean atomism. In the English context, strategies to accommodate atomism to Christian doctrines were fraught with religious and political implications. English Roman Catholics differed from their Protestant compatriots in insisting that God did not cease to operate miracles at the close of the apostolic age. The English friar known as Franciscus à Sancta Clara embraced atomism on the grounds that a new and better science (...) of material causes was indispensable for the accurate assessment of God’s recent and future miracles. (shrink)

Dans le débat sur le partage de l’autorité parentale et la garde alternée, on a assisté d’un côté à la montée en puissance de la notion de « droit des pères », avec sa traduction juridique en termes d’égalisation des droits entre les parents, et, d’un autre côté, à des phénomènes de résistance des hommes à assumer les tâches de la parentalité. Pourtant, avec le maintien des mères dans l’emploi, les conditions sociales qui affectaient le travail domestique et parental aux (...) femmes se sont profondément modifiées. Dans ce contexte, l’image moderne du « nouveau père » n’est-elle pas une actualisation de la figure mythique du père arbitre familial, chargé non plus de la puissance paternelle, mais chargé de rappeler le droit à la mère, soupçonnée de s’être octroyé un pouvoir sur les enfants au moyen de leur prise en charge quotidienne? (shrink)

RESUMO Este artigo tem como objetivo ilustrar a contribuição do dialogismo para o campo de aquisição da linguagem. De acordo com as abordagens dialógicas, as crianças não experienciam unidades e estruturas linguísticas per se; elas experienciam a linguagem em contextos significativos. Mais especificamente, gêneros do discurso, atividades e situações de interação aparecem como mediadores entre o discurso individual, os usos sociais e uma linguagem particular. Para ilustrar as implicações de uma abordagem dialógica, este artigo apresenta uma pesquisa sobre a aquisição (...) de expressões referenciais (projeto DIAREF). As expressões referenciais são particularmente relevantes, já que seu domínio envolve tanto aspectos formais quanto funcionais da língua. Os resultados mostram que os usos de substantivos, pronomes pessoais, pronomes demonstrativos e deslocamentos realizados pelas crianças são determinados em conjunto com os fatores pragmático-discursivos, tais como a posição nos encadeamentos referenciais, e fatores sócio discursivos, tais como gêneros do discurso, atividades e situações interacionais. (shrink)

Presents a history of physics, discussing atoms and elements, radiation and speed of light, and energy fields and forces.

There seems to be a striking parallel between the features of psychopaths and those of agential groups, including states and corporations. Psychopaths are often thought to lack some of the capacities that are constitutive of moral agency. Two features of psychopaths are commonly identified as grounds for limiting their moral responsibility: (i) their lack of relevant emotional capacities and (ii) their flawed rational capacities. Roughly, the first argument is that the lack of moral emotions such as sympathy, guilt, or shame (...) negatively impacts moral perception and therewith an agent's capacity for moral reasoning. The second argument is that psychopaths are diminished in their agency as such, not just in their moral agency; they are erratic and impulsive and show other significant failures of rationality. Using the 2020 Juukan Gorge disaster in Western Australia as a case study, I conclude that deliberate or reckless corporate irrationality cannot be grounds for diminished corporate moral responsibility. Corporate agents are chiefly responsible for core aspects of their moral agency, including their internal epistemic structures and decision-making processes. They have obligations to establish or maintain internal epistemic integrity and consistency. (shrink)

Dans les analyses sociologiques et philosophiques qu'à suscitées récemment le « phénomène du téléphone portable », les promesses de l'innovation sont souvent tenues à tort pour la réalité des usages. Une enquête fondée sur l'observation des pratiques concrètes autour du portable nous a permis de montrer sous quelle forme les possibilités ouvertes par l'innovation interviennent dans l'expérience de l'outil: comment la promesse de joignabilité est déjouée par les stratégies de chacun, comment, à partir d'un agrégat de fonctions, les utilisateurs réinventent (...) un objet métamorphique doté d'une unité forte, ou encore comment les représentations que se font les utilisateurs des possibles techniques les amènent à dénier la réalité de l'outil, dans le cas de la photographie sur portable par exemple...Le cinéma expérimental mobile, ainsi que les films de fiction exploitent cet écart entre les possibles de l'outil et la réalité des pratiques, qui est caractéristique de la relation à cet objet.In sociological and philosophical raised recently as the "phenomenon of the mobile phone," the promise of innovation are often held mistaken for the actual practice. A survey based on the observation of actual practices around the notebook has allowed us to show what form the opportunities offered by innovation involved in the experience of the tool: how the promise of reachability is thwarted by the strategies of each how, from an aggregate function, users metamorphic reinvent an object with a strong unit, or how the representations that are users of possible techniques lead to denying the reality of the tool in the case of photography such as portable ... Experimental cinema mobile, as well as films exploit this potential gap between the tool and the actual practices, which is characteristic of the relationship to the object. (shrink)

Wynn's model for the evolution of spatial cognition is well supported by fossil evidence from brain endocasts, and from neurological studies of the cerebellum and the posterior parietal region of the cerebral cortex. Wynn's intriguing hypothesis that the spatial skill reflected in artifacts is an index of navigational ability, could be further explored by an analysis of lithic transport patterns.

Objective—To identify and describe the current state of clinical ethics support services in the UK.Design—A series of questionnaire surveys of key individuals in National Health Service (NHS) trusts, health authorities, health boards, local research ethics committees and health professional organisations. Interviews with chairmen/women of clinical ethics committees identified in the surveys.Setting—The UK National Health Service.Results—Responses to the questionnaires were received from all but one NHS trust and all but one health authority/board. A variety of models of clinical ethics support were (...) identified including twenty formal clinical ethics committees (CECs). A further twenty NHS trusts expressed an intention to establish a CEC within the next twelve months. Most CECs in the UK have been in existence less than five years and are still defining their role. The chairmen identified education of committee members and contact with other ethics committees as important requirements for committee development. Problems were identified around lack of support for the committee and with raising the profile of the committee within the institution. There has been little evaluation of clinical ethics support services either in the UK or in other countries with longer established services. What evaluation has occurred has focused on process rather than outcome measures.Conclusions—Clinical ethics support services are developing in the UK. A number of issues have been identified that need to be addressed if such support services are to develop effectively. (shrink)

Studies in the behavioral ethics and moral psychology traditions have begun to reveal the important roles of self-related processes that underlie moral behavior. Unfortunately, this research has resulted in two distinct and opposing streams of findings that are usually referred to as moral consistency and moral compensation. Moral consistency research shows that a salient self-concept as a moral person promotes moral behavior. Conversely, moral compensation research reveals that a salient self-concept as an immoral person promotes moral behavior. This study’s aim (...) was to integrate these two literatures. We argued that compensation forms a reactive, “damage control” response in social situations, whereas consistency derives from a more proactive approach to reputation building and maintenance. Two experiments supported this prediction in showing that cognitive depletion (i.e., resulting in a reactive approach) results in moral compensation whereas consistency results when cognitive resources are available (i.e., resulting in a proactive approach). Experiment 2 revealed that these processes originate from reputational (rather than moral) considerations by showing that they emerge only under conditions of accountability. It can thus be concluded that reputational concerns are important for both moral compensation and moral consistency processes, and that which of these two prevails depends on the perspective that people take: a reactive or a proactive approach. (shrink)

La littérature utopique des Lumières explore volontiers les enjeux posés par la sexualité et les rapports de genre. De façon ludique, au théâtre ou dans les contes, ou plus sérieuse – avec notamment le Supplément au voyage de Bougainville de Diderot –, les écrivains du xviiie siècle réinventent l’organisation socio-érotique. Dans le cadre d’une île de fantaisie, ils imaginent tantôt un monde régi par les femmes, tantôt une communauté égalitariste débarrassée des tabous, et appellent parfois de leurs vœux une refondation (...) anthropologique radicale. Cet ailleurs rêvé – qui est aussi un nulle part – autorise, sous le couvert de la fiction, une réflexion originale sur le désir et le pouvoir. (shrink)

A la manière des expériences perceptuelles qui nous présentent des formes, des couleurs, des sons, des textures, etc. les émotions nous présentent des propriétés évaluatives. Ainsi, les émotions constituent un type d’expérience perceptuelle spécifique, un type qui nous donne accès à des valeurs (plutôt qu’à des propriétés non axiologiques). Cette théorie d’origine meinongienne doit beaucoup Christine Tappolet qui y consacre un second livre Emotions, Values and Agency que tous les amoureux des choses vraiment bien faites ne pourront qu’apprécier. Cet article (...) est consacré à deux problèmes auxquels est confronté le partisan de la théorie perceptuelle des émotions, c’est-à-dire, de la théorie selon laquelle les émotions constituent un type spécifique d’expériences perceptuelles. Ce sont les problèmes de la justification et de la rationalité des émotions. Loin d’ignorer ces difficultés, Tappolet y consacre une partie de son premier chapitre (pages 31-45). Cette contribution a plus précisément deux objectifs. Le premier est de montrer pourquoi la justification ne pose pas un problème aussi sérieux que la rationalité à la théorie perceptuelle des émotions. Son second but est d’expliquer pourquoi je doute que la solution de Tappolet au problème de la rationalité fonctionne. (shrink)