This paper aims to identify the key characteristics of model organisms that make them a specific type of model within the contemporary life sciences: in particular, we argue that the term “model organism” does not apply to all organisms used for the purposes of experimental research. We explore the differences between experimental and model organisms in terms of their material and epistemic features, and argue that it is essential to distinguish between their representational scope and representational target. We also examine (...) the characteristics of the communities who use these two types of models, including their research goals, disciplinary affiliations, and preferred practices to show how these have contributed to the conceptualization of a model organism. We conclude that model organisms are a specific subgroup of organisms that have been standardized to fit an integrative and comparative mode of research, and that it must be clearly distinguished from the broader class of experimental organisms. In addition, we argue that model organisms are the key components of a unique and distinctively biological way of doing research using models.Keywords: Experimental organism; Genetics; Model organism; Modeling; Philosophy of biology; Representation. (shrink)

This Element presents a philosophical exploration of the concept of the 'model organism' in contemporary biology. Thinking about model organisms enables us to examine how living organisms have been brought into the laboratory and used to gain a better understanding of biology, and to explore the research practices, commitments, and norms underlying this understanding. We contend that model organisms are key components of a distinctive way of doing research. We focus on what makes model organisms an important type of model, (...) and how the use of these models has shaped biological knowledge, including how model organisms represent, how they are used as tools for intervention, and how the representational commitments linked to their use as models affect the research practices associated with them. This title is available as Open Access on Cambridge Core. (shrink)

The so-called ‘mental files theory’ in the philosophy of mind stems from an analogy comparing object-concepts to ‘files’, and the mind to a ‘filing system’. Though this analogy appears in philosophy of mind and language from the 1970s onward, it remains unclear to many how it should be interpreted. The central commitments of the mental files theory therefore also remain unclear. Based on influential uses of the file analogy within philosophy, I elaborate three central explanatory roles for mental files. Next, (...) I outline several common criticisms of the file picture, which have been a source of resistance to the view. Finally, I outline several interpretations of the theory, thus highlighting that the best interpretation of the file-theory's central analogy remains a live issue. (shrink)

Our aesthetic judgments are embedded in and shaped by unjust social orders. But can our aesthetic judgments themselves—“this is beautiful; that is not”—be unjust? This article argues that they can. Admitting that this is so does not require us to be unduly revisionary with respect to our concept of justice. Rather, the thought that aesthetic judgments are unjust flows naturally from familiar egalitarian constraints.

In Talking about, Unnsteinsson defends an intentionalist theory of reference by arguing that confused referential intentions degrade reference. Central to this project is a “belief model” of both identity confusion and unconfused thought. By appealing to a well‐known argument from Campbell, I argue that this belief model falls short, because it fails to explain the inferential behavior it promises to explain. Campbell's argument has been central in the contemporary literature on Frege's puzzle, but Unnsteinsson's account of confusion provides an opportunity (...) for more clarity about how the argument is best interpreted, and what it shows. (shrink)

"Psychiatry and Philosophy of Science" explores conceptual issues in psychiatry from the perspective of analytic philosophy of science. Through an examination of those features of psychiatry that distinguish it from other sciences - for example, its contested subject matter, its particular modes of explanation, its multiple different theoretical frameworks, and its research links with big business - Rachel Cooper explores some of the many conceptual, metaphysical and epistemological issues that arise in psychiatry. She shows how these pose interesting challenges (...) for the philosopher of science while also showing how ideas from the philosophy of science can help to solve conceptual problems within psychiatry. Cooper's discussion ranges over such topics as the nature of mental illnesses, the treatment decisions and diagnostic categories of psychiatry, the case-history as a form of explanation, how psychiatry might be value-laden, the claim that psychiatry is a multi-paradigm science, the distortion of psychiatric research by pharmaceutical industries, as well as engaging with the fundamental question whether the mind is reducible to something at the physical level. "Psychiatry and Philosophy of Science" demonstrates that cross-disciplinary contact between philosophy of science and psychiatry can be immensely productive for both subjects and it will be required reading for mental health professionals and philosophers alike. (shrink)

Platonic arguments often have premises of a particular form which is misunderstood. These sentences look like universal generalizations, but in fact involve an implicit qua phrase which makes them a fundamentally different kind of predication. Such general implicit redoubled qua predications (girqps) are not an expression of Plato's proprietary views; they are also very common in everyday discourse. Seeing how they work in Plato can help us to understand them.

Pyrrhonian sceptics claim, notoriously, to assent to the appearances without making claims about how things are. To see whether this is coherent we need to consider the philosophical history of ‘appearance’(phainesthai)-talk, and the closely related concept of an impression (phantasia). This history suggests that the sceptics resemble Plato in lacking the ‘non-epistemic’ or ‘non-doxastic’ conception of appearance developed by Aristotle and the Stoics. What is distinctive about the Pyrrhonian sceptic is simply that the degree of doxastic commitment involved in his (...) assent to an impression is asymptotally low. (shrink)

The DSM is the main classification of mental disorders used by psychiatrists in the United States and, increasingly, around the world. Although widely used, the DSM has come in for fierce criticism, with many commentators believing it to be conceptually flawed in a variety of ways. This paper assesses some of these philosophical worries. The first half of the paper asks whether the project of constructing a classification of mental disorders that ‘cuts nature at the joints’ makes sense. What is (...) mental disorder? Are types of mental disorder natural kinds (that is, are the distinctions between them objective and of fundamental theoretical importance, as are, say, the distinctions between the chemical elements)? The second half of the paper addresses epistemic worries. Even if types of mental disorder are natural kinds there may be reason to doubt that the DSM will come to reflect their natural structure. In particular, I examine the extent to which the DSM is theory-laden, and look at how it has been shaped by social and financial factors. Ultimately, I conclude that although the DSM is of immense practical importance it is not likely to become the best possible classification of mental disorders. (shrink)

This discussion emphasises the diversity, philosophical seriousness and methodological distinctiveness of sophistic thought. Particular attention is given to their views on language, ethics, and the social construction of various norms, as well as to their varied, often undogmatic dialectical methods. The assumption that the sophists must have shared common doctrines (not merely overlapping interests and professional practices) is called into question.

Plato’s attitude towards women in his major political works, the Republic and Laws, is complex. On the one hand, Plato argues that in well-run cities, women should hold positions of rule; but on the other, he suggests that women are inferior to men with respect to virtue. To reconcile these conflicting attitudes, some scholars argue that Plato’s progressive proposals are about women as they could be given the right education and environment, while his derogatory comments are about women as they (...) are. Surprisingly, however, commentators who defend this line of thought fail to identify which aspect or aspects of women’s current social position is the problem. I argue that a central problem is women’s role in the private family. More specifically, I argue that Plato thinks the institution of the private family and household is an impediment to virtue; since the private family and household is the primary domain of women, they will be particularly susceptible to its ill effects. In short, individuals’ characters are shaped by the institutions they inhabit; the private family and household is a character-shaping institution that is the primary domain for women, and as a result their characters will be shaped for the worse. (shrink)

Robert Pippin has recently raised what he calls ‘the Montaigne problem’ for Nietzsche's philosophy: although Nietzsche advocates a ‘cheerful’ mode of philosophizing for which Montaigne is an exemplar, he signally fails to write with the obvious cheerfulness attained by Montaigne. We explore the moral psychological structure of the cheerfulness Nietzsche values, revealing unexpected complexity in his conception of the attitude. For him, the right kind of cheerfulness is radically non-naïve; it expresses the overcoming of justified revulsion at calamitous aspects of (...) life through a reflective, higher-order affirmative attitude. This complex notion of cheerfulness turns out to have roots in Montaigne himself, and it must be thought of as a kind of second nature cultivated through practice, as a kind of second nature. Understanding the meaning of cheerfulness thereby sheds light on the conception of philosophy as a way of life in both Nietzsche and Montaigne. (shrink)

What consciousness exactly is remains an unsettled issue among both philosophers and biologists. Three aspects of consciousness are generally recognized: awareness consciousness (through connection...

A generally ignored feature of Plato’s celebrated image of the cave in Republic VII is that the ascent from the cave is, in its initial stages, said to be brought about by force. What kind of ‘force’ is this, and why is it necessary? This paper considers three possible interpretations, and argues that each may have a role to play.

This chapter offers phenomenological ethics of intimacy for experiences of isolation, reduced haptic relations, and periods when we must hold each other at a distance. How can we practice an ethics of intimacy from a space of separation and suspended activities involving bodily proximity and touch? By drawing on Luce Irigaray’s identification of a “caress before the caress,” I locate a queer, feminist ethics of intimacy born from the experience of undetermined desire or “erotic suspension.” The reduction and disruption of (...) touching, brought about by a crisis such as a pandemic, magnifies the experience of ethical or epistemological uncertainty surrounding haptic relations. But I argue that the experience of erotic suspension before the caress underlies all forms of being-together. One’s relationship to this moment before the caress is critical because it informs and transforms the way we are together. The disruption of our usual forms of being-together may be an opportunity for transformed ethical relations, the expansion of intimacy, and heightened sensation and pleasure. (shrink)

Aristotle says little about moral badness [kakia], but his four central claims about it su????ce to entail a rich and plausible account. Badness is the disposition opposed to virtue, and so symmetrical with it in various ways; it is acquired by habituation; it is unlike akrasia in that the bad person’s reason endorses his wrong actions; and this endorsement involves the exercise of a corrupted reason. The activity of corrupted reason must be a kind of (as we now say) motivated (...) reasoning—rationalization, denial and the like—which serves to conceal the correct ends of action from the corrupt person and to sustain their habitual bad behaviour. Although badness is located in the non-rational soul, it is this corruption of reason which turns it into a stable disposition. (shrink)

People with disabilities (PWD) comprise a significant part of the population yet experience some of the most profound health disparities. Among the greatest barriers to quality care are inadequate health professions education related to caring for PWD. Drawing upon the expertise of health professions educators in medicine, public health, nursing, social work, and physician assistant programs, this forum showcases innovative methods for teaching core disability skills and concepts grounded in disability studies and the health humanities. Each of the essays offers (...) practical guidance for developing curricular interventions appropriate for students at various levels of training and familiarity with disability to be implemented in classroom discussions, case-based learning, lectures, panels, and clinical simulations across the full spectrum of pre-health and health professions education. (shrink)

The so-called "biometric-Mendelian controversy" has received much attention from science studies scholars. This paper focuses on one scientist involved in this debate, Arthur Dukinfield Darbishire, who performed a series of hybridization experiments with mice beginning in 1901. Previous historical work on Darbishire's experiments and his later attempt to reconcile Mendelian and biometric views describe Darbishire as eventually being "converted" to Mendelism. I provide a new analysis of this episode in the context of Darbishire's experimental results, his underlying epistemology, and his (...) influence on the broader debate surrounding the rediscovery and acceptance of Mendelism. I investigate various historiographical issues raised by this episode in order to reflect on the idea of "conversion" to a scientific theory. Darbishire was an influential figure who resisted strong forces compelling him to convert prematurely due to his requirements that the new theory account for particularly important anomalous facts and answer the most pressing questions in the field. (shrink)

Socrates’ refutations of Thrasymachus in Republic I are unsatisfactory on a number of levels which need to be carefully distinguished. At the same time several of his arguments are more powerful than they initially appear. Of particular interest are those which turn on the idea of a craft, which represents a shared norm of practical rationality here contested by Socrates and Thrasymachus.

In the U.S. there has been considerable interest in connecting low-income households to alternative food networks like Community Supported Agriculture. To learn more about this possibility we conducted a statewide survey of CSA members in California. A total of 1149 members from 41 CSAs responded. Here we answer the research question: How do CSA members’ socioeconomic and demographic backgrounds, household conditions potentially interfering with membership, and CSA membership experiences vary between lower-income households and higher-income households? We divided members into LIHHs (...) and HIHHs. We present comparisons of LIHHs’ and HIHHs’ employment, race/ethnicity, household composition and education, use of food support, and enjoyment of food-related activities; conditions interfering with membership and major life events; and sources of information influencing decision to join, reasons for joining, ratings of importance of and satisfaction with various CSA attributes, gaps between importance of and satisfaction with various CSA attributes, valuing of the share and willingness to pay more, and impacts of membership. We find that LIHHs are committed CSA members, often more so than HIHHs, and that CSA members in California are disproportionately white, but that racial disproportionality decreases as incomes increase. We conclude by considering: the economic risks that LIHHs face in CSA membership, the intersection of economic risks with race/ethnicity and cultural coding in CSA; and the possibilities of increasing participation of LIHH in CSA. (shrink)

Many philosophers today approach important psychological phenomena, such as weakness of the will and moral motivation, using a broadly Humean distinction between beliefs, which aim to represent the world, and desires, which aim to change the world. On this picture, desires provide the ends or goals of action, while beliefs simply tell us how to achieve those ends. In the Republic, Socrates attempts to explain the phenomena using a different distinction: he argues that the human soul or psyche consists in (...) reason, spirit, and appetite. It is initially tempting to assimilate Socrates’ picture to the standard belief ⁄ desire model, and to think that reason’s role in motivating action is restricted to calculating the best means for satisfying spirited and appetitive desires. But this would be a mistake, since Socrates thinks that each element in the soul is capable of setting the ends of action. But then how exactly should we understand these elements? My aim in this essay is to introduce the reader to Plato’s theory of the tripartite psychology. In part 2, I present Socrates’ argument for the claim that the soul has three elements. In part 3, I provide a general characterization of reason, spirit, and appetite, respectively. I then turn to discuss two central interpretive issues. In part 4, I discuss the sense in which Socrates considers the appetitive and spirited elements to be non-rational. And in the final part of the essay, I discuss the issue of how we ought to conceive of the parts of the soul, and more specifically, whether we should think of them as agent-like parts, or in some other way. (shrink)

A generally ignored feature of Aristotle’s famous function argument is its reliance on the claim that practitioners of the crafts (technai) have functions: but this claim does important work. Aristotle is pointing to the fact that we judge everyday rational agency and agents by norms which are independent of their contingent desires: a good doctor is not just one who happens to achieve his personal goals through his work. But, Aristotle argues, such norms can only be binding on individuals if (...) human rational agency as such is governed by objective teleological norms.
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According to traditional versions of the mental file theory, we should posit _mental files_—that is, mental representations with containment structure—to explain both rational relations between the attitudes, and the persistence of the attitudes across time. However, Goodman and Gray ( 2022 ) offer a revisionary interpretation of the file framework, according to which its explanatory commitments are better presented by positing _mental filing_, as a process, but not _mental files_, as mental representations with file structure. Goodman and Gray focus on (...) a certain class of synchronic explanations, but files have also been thought to play an essential diachronic role in the maintenance and update of object-directed thought. This paper has two aims. First, we clarify the aims and commitments of Goodman and Gray ( 2022 ). Second, we extend their mental filing view to show how it can account for continued belief, change of mind and persistence of the attitudes in general. (shrink)

Plato’s depiction of the first city in the Republic (Book II), the so-called ‘city of pigs’, is often read as expressing nostalgia for an earlier, simpler era in which moral norms were secure. This goes naturally with readings of other Platonic texts (including Republic I and the Gorgias) as expressing a sense of moral decline or crisis in Plato’s own time. This image of Plato as a spokesman for ‘moral nostalgia’ is here traced in various nineteenth- and twentieth-century interpretations, and (...) rejected. Plato’s pessimism about human nature in fact precludes any easy assumption that things, or people, were better in the old days. (shrink)

Among Aristotle’s criticisms of the Form of the Good is his claim that the knowledge of such a Good could be of no practical relevance to everyday rational agency, e.g. on the part of craftspeople. This critique turns out to hinge ultimately on the deeply different assumptions made by Plato and Aristotle about the relation of ‘good’ and ‘good for’. Plato insists on the conceptual priority of the former; and Plato wins the argument.

Are the long, wildly inventive etymologies in Plato’s Cratylus just some kind of joke, or does Plato himself accept them? This standard question misses the most important feature of the etymologies: they are a competitive performance, an agôn by Socrates in which he shows that he can play the game of etymologists like Cratylus better than they can themselves. Such show-off performances are a recurrent feature of Platonic dialogue: they include Socrates’ speeches on eros in the Phaedrus, his rhetorical discourse (...) in the Menexenus, and his literary interpretation in the Protagoras. The paper compares these cases to work out the ground rules, purposes and implications of the Platonic agôn, and the Cratylus etymologies in particular. (shrink)

In a spirit of collegial support, this paper argues that Beckett and Hager’s theoretical justification and empirical exemplifications do not do full justice to the complexity of group or team learning. We firstly reaffirm our support for the theoretical argument Becket and Hager make, though expressing some reservations about Complexity Theory, to explain the taken-for-granted assumptions that learning by an individual is the paradigm case of learning and that context plays a minimal role in this process. Drawing on our joint (...) and separate work, we demonstrate that Becket and Hager’s argument is less radical than it may initially seem because it is predicated on: (i) cognitive-bounded rather than “distributed” or “extended” conception of mind; (ii) material rather than a “immaterial” conception of activity; and (iii) co-present rather than a “fractional” or “connective” conception of ontology. Despite making this critique, we conclude by making the case that we are adding further substance to Becket and Hager’s overarching argument and, in doing so, encouraging them to be more radical about how they conceptualise the complexity of learning. (shrink)

It is very difficult to get a clear picture of how the Stoic is supposed to deliberate. This paper considers a number of possible pictures, which cover such a wide range of options that some look Kantian and others utilitarian. Each has some textual support but is also unworkable in certain ways: there seem to be genuine and unresolved conflicts at the heart of Stoic ethics. And these are apparently due not to developmental changes within the school, but to the (...) Stoics’ having adopted implicitly incompatible solutions in response to different philosophical challenges. (shrink)

This paper explores in detail Gorgias' defense of rhetoric in Plato 's Gorgias, noting its connections to earlier and later texts such as Aristophanes' Clouds, Gorgias' Helen, Isocrates' Nicocles and Antidosis, and Aristotle's Rhetoric. The defense as Plato presents it is transparently inadequate; it reveals a deep inconsistency in Gorgias' conception of rhetoric and functions as a satirical precursor to his refutation by Socrates. Yet Gorgias' defense is appropriated, in a streamlined form, by later defenders of rhetoric such as Isocrates (...) and Aristotle. They present it as an effective reductio against a critique of rhetoric that depends on the "harm criterion." This is puzzling, since Plato 's own critique of rhetoric does not depend on the harm criterion. On the other hand, Plato does seem to embrace the harm criterion as a more general principle—as if pre-emptively embracing the reductio —in his arguments about the good in the Meno and Euthydemus. Nonetheless, Isocrates and Aristotle seem to be deliberately misreading Plato on rhetoric: where he intends to criticize its intrinsic nature, they respond as if he were merely complaining about its contingent effects. (shrink)

The COVID-19 pandemic exposed vulnerabilities in inadequately prioritized healthcare systems in low- and middle-income countries such as Kenya. In this prolonged pandemic, nurses and midwives working at the frontline face multiple ethical problems, including their obligation to care for their patients and the risk for infection with severe acute respiratory syndrome coronavirus 2. Despite the frequency of emergencies in Africa, there is a paucity of literature on ethical issues during epidemics. Furthermore, nursing regulatory bodies in African countries such as Kenya (...) have primarily adopted a Western code of ethics that may not reflect the realities of the healthcare systems and cultural context in which nurses and midwives care for patients. In this article, we discuss the tension between nurses’ and midwives’ duty of care and resource allocation in the context of the COVID-19 pandemic. There is an urgent need to clarify nurses’ and midwives’ rights and responsibilities, especially in the current political setting, limited resources, and ambiguous professional codes of ethics that guide their practice. (shrink)

A recent focus on philosophical methodology has reinvigorated ordinary language philosophy with the contention that philosophical inquiry is better served by attending to the ordinary use of language. Taking cues from findings in the social sciences that deploy methods utilizing language, various ordinary language philosophers embrace a guiding mandate: that ordinary language usage is more reflective of our linguistic and conceptual competencies than standard philosophical methods. We analyze two hypotheses that are implicit in the research from which ordinary language approaches (...) take their cues. This pair of optimistic assumptions (a) bind word meanings to properties of their corresponding concepts and (b) regard language as a direct reflection of our underlying cognitive processes and competencies. Polysemy and pragmatics complicate each assumption. Because the ordinary language philosopher’s methodological mandate compels us to consider how individuals process the utterances they encounter in deciphering the communicative intentions of speakers, failing to attend to the import of polysemy and pragmatics in philosophical and empirical methods has the potential to frustrate the aims of their insightful mandate. The significance of those two complications is worked out with the case study of knowledge. (shrink)

Recent turmoil in the Middle East and North Africa has prompted renewed concerns about women’s rights in Muslim societies. It has also raised questions about women’s agency and activism in religious contexts. This article draws on ethnographic research with women activists in Indonesia, the country with the world’s largest Muslim population, to address such concerns. My fieldwork shows that some Muslim women activists in democratizing Indonesia manifest pious critical agency. Pious critical agency is the capacity to engage critically and publicly (...) with religious texts. While some scholars have argued that pious and feminist subjectivity are inherently at odds, the emergence of pious critical agency in Indonesia demonstrates that piety and feminism can intersect in surprising and unexpected ways. Moreover, it shows that women’s agency can draw on both secular and religious resources and that religion can be used to promote critical discourses on gender. (shrink)

A sentimentalist theory of morality explains all moral evaluations as manifestations of certain emotions, ones that David Hume and Adam Smith, in their related but divergent accounts, call moral sentiments. The two theories have complementary successes and failures in capturing familiar features of the experience of making moral evaluations. Thinking someone courageous or dishonest need not involve having goals or feelings of desire, and Hume’s theory captures that well; but its account of how our moral evaluations are about or directed (...) toward people or actions is deficient. Smith’s theory readily explains how moral sentiments can be about things (and which things they are about), but at the cost of construing some central moral evaluations as goal-directed desires that are simply not like that. Present-day sentimentalists also face the challenge of combining these two desiderata. (shrink)

Socrates' aim in the Republic is to show that being just is crucial for happiness. In Republic IV, Socrates argues that the just individual is one in whom each part of the soul or psyche performs its proper function, with the result that the individual attains psychic harmony. Commentators have worried, however, that this account of what it is to be just has little to do with being just in the ordinary sense of the term, which involves acting with regard (...) for the good of others. In this essay, I describe three attempts to show that there is a connection between Socrates' account of justice and justice in the ordinary sense of the term and I raise criticisms of each. I then outline my own approach, which emphasizes the importance of good relations with others for happiness. (shrink)

Background Coping with end-of-life issues is a major challenge for governments and health systems. Despite progress in legislation, many barriers exist to its full implementation. This study is aimed at identifying these end-of-life barriers in relation to Israel. Methods Qualitative in-depth interviews using professionals and decision makers in the health-care and related systems were carried out, along with two focus groups based on brainstorming techniques consisting of nurses and social workers. Data was managed and analyzed using Naralyzer software. Results Qualitative (...) analysis showed identification of six primary barriers: 1) law, procedures, and forms; 2) clinical aspects; 3) human aspects; 4) knowledge and skills of medical teams; 5) communication; and 6) resource allocation. These were further divided into 44 sub area barriers. Conclusions This study highlights the role of the family doctor in end-of-life by training physicians in decision-making workshops and increasing their knowledge in the field of palliative medicine. Effectively channeling resources, knowledge, and support for medical teams, by accounting for the structure and response of the units for home treatment will improve patient’s access to information on and support for end-of-life laws, as well as reduce legislative barriers in other countries that face the same issues. (shrink)

Apuleius’s The Golden Ass presents curiosity as the protagonist’s downfall, yet ultimately recodes curiosity as the single virtue through which the human soul achieves not only immortality but joy. I identify Apuleius’s treatment of curiosity as falling into the categories of erotic and nonerotic. The union of Eros and the curious human soul suggests that one who is erotically curious can take pleasure in her devotion to one, precisely because she has eyes for the beauty of many.

Simplicius’ project of harmonizing previous philosophers deserves to be taken seriously as both a philosophical and an interpretive project. Simplicius follows Aristotle himself in developing charitable interpretations of his predecessors: his distinctive project, in the Neoplatonic context, is the rehabilitation of the Presocratics (especially Parmenides, Anaxagoras and Empedocles) from a Platonic-Aristotelian perspective. Simplicius’ harmonizations involve hermeneutic techniques which are recognisably those of the serious historian of philosophy; and harmonization itself has a distinguished history as a constructive philosophical method.