This article conducts a brief review of works dealing with recognition processes in media environments, with a special focus on social media platforms. It argues that efforts to analyze dynamics of recognition in datafied spaces should take into consideration the working logics of such platforms, which are responsible for the organization of media practices around the creation of economic value for the companies. The article examines the news feeds as a type of social space where these logics are manifested in (...) the decisions of the platforms about what and when to show to their users. In this context, practices of sociability aimed at increasing recognition in social media platforms should be understood within a broader movement of datafication of society, which deepens the presence of capitalist logics in social life. (shrink)

A contemporary of Giordano Bruno and Galileo, Tommaso Campanella was a controversial philosopher, theologian, astrologer, and poet who was persecuted during the Inquisition and spent much of his adult life imprisoned because of his heterodox views. He is best known today for two works: _The City of the Sun_, a dialogue inspired by Plato’s _Republic_, in which he prophesies a vision of a unified, peaceful world governed by a theocratic monarchy; and his well-meaning _Defense of Galileo_, which may (...) have done Galileo more harm than good because of Campanella’s previous conviction for heresy. But Campanella’s philosophical poems are where his most forceful and undiluted ideas reside. His poetry is where his faith in observable and experimental sciences, his astrological and occult wisdom, his ideas about deism, his anti-Aristotelianism, and his calls for religious and secular reform most put him at odds with both civil and church authorities. For this volume, Sherry Roush has selected Campanella’s best and most idiosyncratic poems, which are masterpieces of sixteenth-century Italian lyrics, displaying a questing mind of great, if unorthodox, brilliance, and showing Campanella’s passionate belief in the intrinsic harmony between the sacred and secular. (shrink)

Renaissance magic was an attempt to supply Platonism with a philosophy of nature that could compete with Aristotelian physics. It was expected to heal the increasing breach between science and faith. However, the basic presupposition of every magic worldview, the notion of a living universe, favors immanentism and arguably hastened the rise of secularism. Secularism, it should be noted, was not an identifiable set of theories but a process towards modernity with its correspondent philosophical theology. Three different stages in that (...) development can be shown in the philosophical systems of three famous Renaissance magicians: Henry Cornelius Agrippa, Giordano Bruno, and Tommaso Campanella. (shrink)

La cena de le ceneri. Scelta dal dialogo De gli eroici furori. Autobiografia (dagli atti processuali), di G. Bruno.--Poesie. La città del sole. Discorsi universali del governo ecclesiastico, di T. Campanella.

Benedetto Croce was a keen reader of the Italian works of Giordano Bruno when Giovanni Gentile published the Dialoghi metafisici e morali in 1907-1908. Just like his mentor Francesco De Sanctis, Croce sees Bruno as "a great thinker" and "a great writer". What he attaches great value to above all is Bruno as a philosopher deeply engaged in distinguishing between science and philosophy and combating the Aristotelians of the Renaissance. He used Bruno in his own fight (...) against the "Aristotelians" of his age: the Neo-Kantians. In his interpretation of the Italian Renaissance as the age of rationalism, whose main thread was soon broken, Croce puts Bruno and Campanella among the «few scattered and scared apostles of the future» who continued to weave the thread of rationality, later taken up by Vico and Giannone and, finally, by the Italian Risorgimento, starting with the Neapolitan patriots of 1799. When he defined the Italian Renaissance as the historical age of the emersion of rationality and of a true break the tradition, Croce made use of the fundamental intuition of Spaventa and of some of the latter’s disciples. They had stressed in the name of Bruno the sharp break between the Middle Ages and Renaissance philosophy while Croce here came closest to the philosopher from Nola, who had made a trenchant critique of the biblical myth of the "golden age". (shrink)

All of the selections in this volume have been newly translated and many of them appear for the first time in English. The editors group well-chosen selections from the Renaissance Italian philosophers around four areas of development of philosophy passing out of the middle ages and into modern philosophy. Renaissance Humanism is represented by Petrarch, Leon Alberti, Lorenzo Valla, and Gianozzo Manetti. Renaissance Platonism includes selections from Pico della Mirandola, Marsilio Ficino, and Leone Ebreo. Renaissance Aristotelianism has pieces from Pomponazzi (...) and Tasso. The Philosophers of Nature included are Telesio, Campanella, and Bruno. Courses in the History of Philosophy too often pass over the Renaissance philosophers, much in the same way as these same courses used to pass over the Middle Ages. Considering the effect that the revitalized Platonism of the Renaissance period had on Descartes and Leibniz, this gap needs to be filled in for a proper understanding of the origins of modern philosophy; this anthology, and, presumably, the companion volume to follow are welcome steps in that direction.—E. A. R. (shrink)

The story of the beliefs and practices called 'magic' starts in ancient Iran, Greece, and Rome, before entering its crucial Christian phase in the Middle Ages. Centering on the Renaissance and Marsilio Ficino - whose work on magic was the most influential account written in premodern times - this groundbreaking book treats magic as a classical tradition with foundations that were distinctly philosophical. Besides Ficino, the premodern story of magic also features Plotinus, Iamblichus, Proclus, Aquinas, Agrippa, Pomponazzi, Porta, Bruno, (...) Campanella, Descartes, Boyle, Leibniz, and Newton, to name only a few of the prominent thinkers discussed in this book. Because pictures play a key role in the story of magic, this book is richly illustrated. (shrink)

Wonder, miracle, occult science, poetry, and the epistemological implications in Renaissance authors: Marsilio Ficino, Giovanni Pico, Pietro Pomponazzi, Agrippa of Nettesheim, Giordano Bruno, Francesco Patrizi, Tommaso Campanella, Francisco Suárez.

Contents: Preface; From faith to reason for fideism: Raymond Lull, Raimundus Sabundus and Michel de Montaigne; Nicholas of Cusa and Pythagorean theology; Giordano Bruno's philosophy of religion; Coluccio Salutati: hermeneutics of humanity; Humanism applied to language, logic and religion: Lorenzo Valla; Georgios Gemistos Plethon: from paganism to Christianity and back; Marsilio Ficino's philosophical theology; Giovanni Pico against popular Platonism; Tommaso Campanella: God makes sense in the world; Francisco Suárez – scholastic and Platonic ideas of God; Epilogue: conflicting truth (...) claims; Bibliography; Index. (shrink)

Tommaso campanellae.--Giordano Bruno.--Del principio della riforma religiosa, politica e filosofica nel secolo XVI.--Mamiani.

Giordano Bruno (1548-1600), who died at the stake, is one of the best-known symbols of anti-establishment thought. The theme of this volume, which is offered as a collection of essays to honor the distinguished Bruno scholar Hilary Gatti, reflects her constant concern for the principles of cultural freedom and independent thinking. Several essays deal with Bruno himself, including an analysis of the Eroici furori, a study of his reception in relation to the group known as the Novatores, (...) and discussions of several important aspects of his stay in England. The authors and texts discussed here are linked by a relentless interest in the question of authority and originality, and they range from literary figures such as Alberti (1404-72), Vasari (1511-74) and the proponents of quantitative verse in sixteenth-century England to controversial philosophers who, like Bruno, were condemned by the Church, such as Tommaso Campanella (1568-1639) and Giulio Cesare Vanini (1585-1619). Taken together, these chapters show how much that was new and revolutionary in early modern culture came from its confrontation with the past. Martin McLaughlin is Agnelli-Serena Professor of Italian at Oxford. Elisabetta Tarantino is a Teaching Fellow in the Department of Italian at the University of Warwick. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:THE 'NATURALNESS' OF NATURAL RELIGION Among Hume's philosophical works the Dialogues Concerning Natural Religion is unquestionably the easiest to read. One can easily imagine a precocious fifteen-year-old like Miss Jane Austen — who set herself to write her own History of England only a decade or so after Hume's death — coming upon the little volume that nephew David published, reading it with great excitement (and a steadily rising (...) intellectual fury), and recording the same verdict that Pamphilus offers us, but in much more 2 trenchant terms. we can also imagine her reading it again twenty years later, armed with an explanatory commentary like the one that Stanley Tweyman has now given us, and maintaining her position (this time in the more temperate terms of Pamphilus himself). For Miss Jane Austen at thirty-five had one of the most critically commonsensical minds of her time; and she was also a person of deep religious feeling. It is in defence of her feelings, rather than of my own, that this essay is written. For she was close enough to what I take to have been Hume's position to have agreed with it once she had understood it; I, on the other hand, am not. To claim that a meeting of minds between the Rector of Steventon' s daughter and the Scottish apostle of infidelity is even conceivable may seem ridiculous. Hume himself would never have thought it likely. But even if my estimate is unduly optimistic, it serves at least to underline the importance of Tweyman' s constructive commentary. For without Tweyman 's commentary, Jane Austen's reaction to the Dialogues would have been one of morally indignant, and quite categorical rejection at any age. With it to guide her, she would have been appreciative and sympathetic, even if she was still ultimately dissatisfied. (I hope to persuade those who admire them both, as I do, that David Hume and Jane Austen belonged to the same 'invisible Church'). To read the Dialogues is still relatively easy. We only have to know that we are listening to a conversation between educated men in a society where everyone professes (at least) to believe that the world they were born into was created by a God who is all-knowing and all-powerful, infinitely wise, infinitely just and good, and, above all, infinitely loving towards the only creatures in his world who are capable of recognizing what he has done for them. The Rector of Steventon's daughter would have had difficulty in appreciating the discussion properly, because she had some further, more specific, beliefs about God's relations with his beloved children. We have some (smaller) difficulties now, because we are far from believing so much (and many of us believe nothing of the sort at all). But to grasp what we are supposed to believe is not difficult; and once we know that, the conversation itself is easy to follow. Only once does it seem to get out of hand to the point of actual implausibility; and there are only three things about it that are genuinely puzzling. The conversation does not reach any conclusion — at least none that convinces us. We are not convinced because the obvious solution for the most pervasive of our three puzzles is the assumption that Philo, the speaker who appears to state an agreed conclusion, is only pretending. That he should pretend is quite right and proper for a modern philosophical dialogue. Augustine may have written straightforward expository (or 'dogmatic') dialogues; and Berkeley, following in the wake of some of Augustine's medieval imitators, may have managed to raise this form into the best imitation of a live discussion that has been achieved for the dogmatic dialogue in English. But the religious doctrine of these 'dogmatists' was orthodox. One glance at the fortunes of the great Italian dialogue writers — Bruno, Galileo, Campanella — is enough to teach us that it was not prudent to let one's own doctrine win openly when one was teaching against the Church. Jane Austen would certainly have adopted the hypothesis that Philo's professions of religious feeling are hypocritical throughout the discussion. She would have assumed that Cleanthes... (shrink)

"La filosofí­a florentina en el jardí­n de Adán" La Modernidad ha tenido enormes dificultades para reconocer plenamente al Humanismo como parte de toda su incuestionable tradición filosófica y en particular de reconocer al Humanismo florentino a partir de sus propuestas filosóficas como lo que en esencia ellas son, representaciones concretas, históricas, del mundo. Tales dificultades radican en la imposibilidad de no poder o no querer superar sus propios parámetros y esquemas de explicación y reconstrucción histórica. Pues si algo es cierto, (...) es que filosofí­as como las de Pico della la Mirandola, Marsilio Ficino, Poliziano, Pomponazzi, Tommaso Campanella y Giordano Bruno, contienen todas ellas una constante común: la dificultad de ser explicadas y comprendidas a la luz de la razón y de la cientificidad modernas. "The Florentine philosophy in Adam's garden" The Modernity had had enormous difficulties to recognize fully the Humanism like apart of all its unquestionable philosophical tradition and in particular of recognizing the Florentine Humanism starting from its philosophical proposals as what in essence they are, concrete, historical representations, of the world. Such difficulties reside in the impossibility of not to be able, or not to want to overcome, their own parameters and explanation's outlines and historical reconstruction. Because if something is true, it is that philosophies like those of Pico della la Mirandola, Marsilio Ficino, Poliziano, Pomponazzi, Tommaso Campanella and Giordano Polish, all of them contain a common constant: the difficulty of being explained and understood by the light of the reason and in the modern scientific approach. (shrink)

"La filosofí­a florentina en el jardí­n de Adán" La Modernidad ha tenido enormes dificultades para reconocer plenamente al Humanismo como parte de toda su incuestionable tradición filosófica y en particular de reconocer al Humanismo florentino a partir de sus propuestas filosóficas como lo que en esencia ellas son, representaciones concretas, históricas, del mundo. Tales dificultades radican en la imposibilidad de no poder o no querer superar sus propios parámetros y esquemas de explicación y reconstrucción histórica. Pues si algo es cierto, (...) es que filosofí­as como las de Pico della la Mirandola, Marsilio Ficino, Poliziano, Pomponazzi, Tommaso Campanella y Giordano Bruno, contienen todas ellas una constante común: la dificultad de ser explicadas y comprendidas a la luz de la razón y de la cientificidad modernas. "The Florentine philosophy in Adam's garden" The Modernity had had enormous difficulties to recognize fully the Humanism like apart of all its unquestionable philosophical tradition and in particular of recognizing the Florentine Humanism starting from its philosophical proposals as what in essence they are, concrete, historical representations, of the world. Such difficulties reside in the impossibility of not to be able, or not to want to overcome, their own parameters and explanation's outlines and historical reconstruction. Because if something is true, it is that philosophies like those of Pico della la Mirandola, Marsilio Ficino, Poliziano, Pomponazzi, Tommaso Campanella and Giordano Polish, all of them contain a common constant: the difficulty of being explained and understood by the light of the reason and in the modern scientific approach. (shrink)

In a letter addressed to Mercator in 1558, John Dee made an odd announcement, describing the Portuguese mathematician and cosmographer Pedro Nunes as the ‘most learned and grave man who is the sole relic and ornament and prop of the mathematical arts among us’, and appointing him his intellectual executor. This episode shows that Dee considered Nunes one of his most distinguished contemporaries, and also that some connection existed between the two men. Unfortunately not much is known about this connection, (...) and even such basic questions such as ‘What could John Dee know about this Portuguese cosmographer’s scientific work?’ or ‘When, why and where did this interest come about?’ still lack proper answers. In this paper I address this connection and examine Nunes’ influence on Dee’s mathematical work. I argue that Dee was interested in Nunes’ work as early as 1552 . I also claim that Dee was aware of Nunes’ programme for the use of mathematics in studying physical phenomena and that this may have influenced his own views on the subject. (shrink)

Das Buch versteht sich zugleich als Begriffsgeschichte von "Selbsterhaltung" in der Renaissance und als Rekonstruktion der Philosophie Bernardino Telesios (1509-1588), der den Begriff erstmals zum Zentrum neuzeitlicher Naturphilosophie und Ethik gemacht hat. Telesios Denken wird aus internen Entwicklungen der aristotelischen Philosophie und der galenischen Medizin verständlich gemacht, und es wird gezeigt, wie seine "defensive Modernisierung" zugleich zum Katalysator für spekulative philosophische Entwicklungen am Ende des 16. Jahrhunderts wird: bei Bruno, Patrizi, Stelliola und Campanella. Denn anders als in der (...) als "Beharrung" gedachten conservatio sui nach Descartes geht es in der Begriffsentwicklung der Renaissance um Sensualität, Ähnlichkeit und Lebenswärme. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 249 Girolamo Balduino: Ricerche sulla logica della Scuola di Padova nel Rinascimento. By Giovanni Papuli. (Bark Lacerta, Universith di Bari, Pubblicazioni dell'lstituto di filosofia, 12, 1967. Pp. 313. no price.) The philosophers at the University of Padua during the late Middle Ages and Renaissance arc attracting much renewed interest. This study makes accessible again the logical philosophy of Girolamo Balduino, professor at Padua during the second quarter (...) of the sixteenth century. Like other thinkers of his period, 13alduino follows the logic of Aristotle, and looks for progress within the ancient and mediaeval tradition, not for radically new doctrines. He continues the traditional interpretation of Aristotle by Averroes, for whom logic is only an instrumental habitus, a tool or method of demonstration. About the final contribution of the school of Padua to the improvement of Aristotelian logic was the doctrine of regressive demonstration, where demonstration terminates in or discloses the definition. Zabarella's well-known teaching on this point seems to be derived entirely from Balduino. Contrary to the interpretation of Cassirer, followed by Randall, this regressive demonstration is not a universal method of inquiry and is not at all like, and not the historical source of, the new method of Galileo. Papuli's book is solidly based on the original Latin texts, in notes, which are of great value in view of the fact that Balduino's works have been out of print since 1573. Not all of Papuli's interpretations are beyond criticism (e.g., p. 296), but he has done a service in enabling us to reestablish contact with one of the last significant commentators on Aristotle's logic. PAUL J. W. MILLER University of Colorado Documents sur la vie de Jules-Cdsar Vanini de Taurisano. By Emile Namer. (Bari: Adriatica Editrice, n.d.=Univcrsith degli Studi di Bari, Pubblicazioni delFIstituto di Filosofia, II serie, Testi e Documenti, I. Pp. 196+22 facsimile illustrations) Giulio Cesare Vanini (1585-1619) ranks with Giordano Bruno as a modern hero of freedom of philosophical expression. He was tortured and then burned at the stake in Toulouse at the age of thirty-four, because of the unorthodoxy of his views. For this reason, he has drawn more attention than is perhaps deserved on the basis of his rather mediocre writings, which are little more than a tissue of plagiarisms culled from Pomponazzi, Cardano, J. C. Scaliger, and others. In this volume, Emile Namer has collected the scattered documents dealing with Vanini's life and activities. This is a valuable service, for it should enable scholars to disentangle fact from fiction and reality from myth. There has been so much heated discussion regarding Vanini that it is now time that someone should attempt to establish the precise facts and to reevaluate Vanini's place in intellectual history. In the past, writings about him have been governed more often by emotion than by reason. Namer prints documents from Naples, London, Paris, Simancas, and Toulouse. Some of these have been printed before in various journal articles, but it is valuable to have them all together in a single volume. In addition, he prints relevant excerpts concerning--as one of them put it--le douzi~me apostre de Satan, including material from Mersenne, Garasse, and others. He also includes a series of facsimiles of sample pages from the documents which he prints. All in all Namer's work is competently 250 HISTORY OF PHILOSOPHY done, though perhaps a bit more annotation to put the documents in historical perspective would have been desirable. In any case this little volume must be one of the bases for any future serious biographical or interpretative studies dealing with Vanini. Moreover, it shouM also be useful for scholars dealing with more general questions of seventeenth-century intellectual, religious, and social history. Unfortunately, there is no index, nor bibliography of earlier literature on Vanini, and the Introduction is perhaps too brief to orient the reader who has little previous knowledge of Vanini. CHARLES B. SCHMITT University oJ Leeds Tommaso Campanella: Renaissance Pioneer o[ Modern Thought. By Bernardino M. Bonansea. (Washington: Catholic University of America Press, 1969. Pp. xi 421. $14.50) This excellent critical study of the life and... (shrink)

Dès 1983, à l’occasion du colloque Une histoire des femmes est-elle possible? qui allait marquer le véritable départ de l’histoire des femmes en France, Alain Corbin soulignait la nécessité de se pencher aussi sur les « mentalités masculines », afin que puisse émerger une « histoire sexuée qui couple ses analyses ». L’auteur des Filles de noce resta longtemps peu entendu. Cette dernière décennie a pourtant vu une nette évolution s’amorcer, les masculinités françaises devenant peu à peu un ch...

PHILOSOPHERS have traditionally appreciated the relevance of Galileo in a number of ways. First, since his scientific contributions made him the "father of modern science," or at least one of its founders, philosophers like Husserl, Ortega y Gasset, and Burtt have studied his work to determine its epistemological implications and metaphysical foundations; this kind of approach is pursued more or less systematically by professional philosophers of science, for whom Galileo's work has become a standard test case for their theses and (...) analyses, as we find in books by Paul Feyerabend, Thomas Kuhn, and Dudley Shapere. Second, since he was subjected to an Inquisition trial and condemnation that came to be labeled "the greatest scandal in Christendom," the interpretation and appraisal of the Galileo affair has become a cause célèbre, attracting the attention of cultural generalists and resulting in works of socio-political criticism with an anti-clerical tendency and of theological apologetics. A third type of philosophical appreciation has consisted in exploring and establishing conceptual and empirical ties between Galileo and the history of philosophy as such, which can be done and has been done in regard to his philosophical contemporaries such as Bacon, Hobbes, Descartes, Bruno, and Campanella, as well as successors like Hume, and predecessors like Plato; the last connection, in particular, had recently acquired some popularity, after having been pioneered by Koyré's celebrated "Galileo and Plato" in the pages of the Journal of the History of Ideas. More recently, the present reviewer has elaborated a fourth type of philosophical appreciation of Galileo, from the point of view of what is now generally called "informal logic." Here Galileo's work becomes a model for the analysis and evaluation of given arguments and for the construction of new ones, as well as a data base for the elaboration of a theory of reasoning oriented toward practice, applications, and everyday use. (shrink)

Leggiamo nell'Histoire de la philosophie cartèsienne, di Francisque Boullier, che giorno, mentre Malebranche e Fontenelle entravano nell'Oratoire Saint-Honoré, la cagna di casa, gravida, si avvicinò a Malebranche per fargli delle effusioni, ricevendone però solo calci. Quando Fontenelle sembrò commuoversi, fu liquidato con una sentenza: 'Non lo sai che non sente nulla?'. Malebranche era un filosofo cartesiano e, così agendo e parlando, stava traendo ovvie conclusioni dalle Meditazioni del maestro: solo chi ha una mente prova sensazioni; gli animali sono pura materia (...) e non hanno una mente; se si lamentano, i suoni che emettono valgono come i rumori emessi da una macchina. Questa metafisica stracciona, divulgata in un periodo storico in cui Giordano Bruno e Tommaso Campanella descrivevano invece un universo interamente animato, è risultata vincente nel mondo contemporaneo e ne ha sottoscritto l'atteggiamento predatorio e sfruttatore nei confronti della Natura. Schiavista, anche, perché forse anche i popoli diversi da quello dominante 'non sentono nulla'. È tempo di riscrivere le meditazioni cartesiane, non perché la metafisica abbia mai cambiato il mondo ma per eliminare gli alibi e i pretesti che una cattiva metafisica, serva dei potenti, è lieta di offrire loro. Bencivenga si dedica qui a questo compito, e lasceremo che siano le sue pagine a parlare. Aggiungeremo solo che Bruno e Campanella, oltre a Kant, sono i fari che gli illuminano la strada, e che scrive dal punto di vista di una cagna gravida e maltrattata."--Page 4 of cover. (shrink)

Bernardino Telesio Dubbed “the first of the new philosophers” by Francis Bacon in 1613, Bernardino Telesio was one of the most eminent thinkers of Renaissance Italy, along with figures such as Pico, Pomponazzi, Cardano, Patrizi, Bruno, Doni, and Campanella. The young Telesio spent the early decades of his life under the guidance of his … Continue reading Telesio, Bernardino →.

The use of forward models is well established in cognitive and computational neuroscience. We compare and contrast two recent, but interestingly divergent, accounts of the place of forward models in the human cognitive architecture. On the Auxiliary Forward Model account, forward models are special-purpose prediction mechanisms implemented by additional circuitry distinct from core mechanisms of perception and action. On the Integral Forward Model account, forward models lie at the heart of all forms of perception and action. We compare these neighbouring (...) but importantly different visions and consider their implications for the cognitive sciences. We end by asking what kinds of empirical research might offer evidence favouring one or the other of these approaches. (shrink)

The economic crisis happening across the world over the last few years describes a range of interdependencies and interactions,and has highlighted the fundamentalf laws of neoclassical economic theory: its unedifying focus on prediction and, above all, its inability to explain how the economy really works. As such, it is increasingly recognised that economic phenomena cannot be exclusively investigated as being derived from deterministic, predictable and mechanistic dynamics. Instead, a new approach is required by which history-dependence, organic and ever-evolving processes are (...) also accounted for. As this view implies new challenges and opportunities for policy, we will focus our attention on innovative components of Complexity Theory for the study of economics and the evaluation of public policies. (shrink)

Using a metacontrast masking paradigm, prior studies have shown that a target’s color information and form information, can be processed without awareness and that unconscious color processing occurs at early, wavelength-dependent levels in the cortical information processing hierarchy. Here we used a combination of paracontrast and metacontrast masking techniques to explore unconscious color and form priming effects produced by blue, green, and neutral stimuli. We found that color priming in normal observers is significantly reduced when an additional paracontrast mask precedes (...) the target at optimal masking SOAs. However, no reduction of form-priming effects was obtained at similar optimal paracontrast SOAs. We conclude that unconscious color priming depends on an early, wavelength- or stimulus-dependent response of color neurons located at early cortical levels whereas unconscious form priming occurs at later levels. (shrink)

SummaryMutations in human genes encoding transcription factors are often dominant because one active allele cannot ensure a normal phenotype (haploinsufficiency). In other instances, heterozygous mutations of two genes are required for a phenotype to appear (combined haploinsufficiency). Here, we explore with models (i) the basis of haploinsufficiency and combined haploinsufficiency owing to mutations in transcription activators, and (ii) how the effects of such mutations can be amplified or buffered by subsequent steps in a transcription cascade. We propose that the non‐linear (...) (sigmoidal) response of transcription to the concentration of activators can explain haploinsufficiency. We further show that the sigmoidal character of the output of a cascade increases with the number of steps involved, the settings of which will determine the buffering or enhancement of the effects of a decreased concentration of an upstream activator. This exploration provides insights into the bases of compensatory mutations and on interloci interactions underlying oligogenic inheritance patterns. (shrink)