This fine collection of essays by a leading philosopher of science presents a defence of integrative pluralism as the best description for the complexity of scientific inquiry today. The tendency of some scientists to unify science by reducing all theories to a few fundamental laws of the most basic particles that populate our universe is ill-suited to the biological sciences, which study multi-component, multi-level, evolved complex systems. This integrative pluralism is the most efficient way to understand the different and complex (...) processes - historical and interactive - that generate biological phenomena. This book will be of interest to students and professionals in the philosophy of science. (shrink)

Explores what the last few decades of European/American, feminist, and postcolonial science and technology studies can learn from each other. This book proposes new directions for thinking about objectivity, method, and reflexivity in light of the new understandings developed in the post-World War II world.

Biological knowledge does not fit the image of science that philosophers have developed. Many argue that biology has no laws. Here I criticize standard normative accounts of law and defend an alternative, pragmatic approach. I argue that a multidimensional conceptual framework should replace the standard dichotomous law/ accident distinction in order to display important differences in the kinds of causal structure found in nature and the corresponding scientific representations of those structures. To this end I explore the dimensions of stability, (...) strength, and degree of abstraction that characterize the variety of scientific knowledge claims found in biology and other sciences. (shrink)

Beatty, Brandon, and Sober agree that biological generalizations, when contingent, do not qualify as laws. Their conclusion follows from a normative definition of law inherited from the Logical Empiricists. I suggest two additional approaches: paradigmatic and pragmatic. Only the pragmatic represents varying kinds and degrees of contingency and exposes the multiple relationships found among scientific generalizations. It emphasizes the function of laws in grounding expectation and promotes the evaluation of generalizations along continua of ontological and representational parameters. Stability of conditions (...) and strength of determination in nature govern projectibility. Accuracy, ontological level, simplicity, and manageability provide additional measures of usefulness. (shrink)

The `fact' of pluralism in science is nosurprise. Yet, if science is representing andexplaining the structure of the oneworld, why is there such a diversity ofrepresentations and explanations in somedomains? In this paper I consider severalphilosophical accounts of scientific pluralismthat explain the persistence of bothcompetitive and compatible alternatives. PaulSherman's `Levels of Analysis' account suggeststhat in biology competition betweenexplanations can be partitioned by the type ofquestion being investigated. I argue that thisaccount does not locate competition andcompatibility correctly. I then defend anintegrative (...) model for understanding pluralism. This view is based on taking seriously both thecomplexity and contingency of biologicalorganization and the idealized character ofbiological models. On this view, explanationbecomes, among other things, the location forthe integration of diverse models. I explicatemy argument by an analysis of explanations ofdivision of labor in social insects. (shrink)

This book offers a detailed study of the political philosophies of Thomas Hobbes and Benedict de Spinoza, focussing on their concept of power as potentia, concrete power, rather than power as potestas, authorised power. The focus on power as potentia generates a new conception of popular power. Radical democrats–whether drawing on Hobbes's 'sleeping sovereign' or on Spinoza's 'multitude'–understand popular power as something that transcends ordinary institutional politics, as for instance popular plebsites or mass movements. However, the book argues that these (...) understandings reflect a residual scholasticism which Hobbes and Spinoza ultimately repudiate. Instead, on the book's revisionist conception, a political phenomenon should be said to express popular power when it is both popular (it eliminates oligarchy and encompasses the whole polity), and also powerful (it robustly determines political and social outcomes). Two possible institutional forms that this popular power might take are distinguished: Hobbesian repressive egalitarianism, or Spinozist civic strengthening. But despite divergent institutional proposals, the book argues that both Hobbes and Spinoza share the conviction that there is nothing spontaneously egalitarian or good about human collective existence. From this point of view, the book accuses radical democrats of pernicious romanticism; the slow, meticulous work of organizational design and maintenance is the true centre of popular power. Three minute video summary available via HPBin3. Extended discussion on The Political Theory Review podcast. First chapter open access available via Oxford Scholarship Online. Videos of book talks at National University of Singapore (Centre for Legal Theory) and Universidad de Buenos Aires (Instituto de Investigaciones Gino Germani) available via YouTube. (See links below.). (shrink)

The controversy regarding the unit of selection is fundamentally a dispute about what is the correct causal structure of the process of evolution by natural selection and its ontological commitments. By characterizing the process as consisting of two essential steps--interaction and transmission--a singular answer to the unit question becomes ambiguous. With such an account on hand, two recent defenses of competing units of selection are considered. Richard Dawkins maintains that the gene is the appropriate unit of selection and Robert Brandon, (...) in response, argues that the individual organism is better suited to the role. This paper argues that by making explicit the underlying questions that each of these views addresses, the apparent conflict can be resolved. Furthermore, such a resolution allows for a more complete and realistic understanding of the process of evolution by natural selection. (shrink)

This work runs counter to the traditional interpretations of Peirce's philosophy by eliciting an inherent strand of pragmatic pluralism that is embedded in the very core of his thought and that weaves his various doctrines into a systematic ...

Drawing on J. L. Austin and the later works of Ludwig Wittgenstein, she argues for the solution provided by ordinary language philosophy—a philosophy that trusts and utilizes the everyday use of language and the clarity of meaning it ...

James articulates and defends a Spinozist view of the interplay between poetry and philosophy: philosophy has an ineliminably poetic content, and poetry is an aid and support to philosophy. In this piece, I juxtapose James’s Spinozist schema with another schema available within Spinoza’s historical milieu. In Ibn Tufayl’s view, rather than poetry being an aid to philosophy, poetry opens to a world of experience that even the best philosophy cannot grasp. For flat-footed philosophers who think that philosophy can in principle (...) have the last word on everything, poetics might give an approximate indication of a kind of experience that lies beyond it. (shrink)

ABSTRACT It has long been held that the structure of a protein is determined solely by the interactions of the atoms in the sequence of amino acids of which it is composed, and thus the stable, biologically functional conformation should be predictable by ab initio or de novo methods. However, except for small proteins, ab initio predictions have not been successful. We explain why this is the case and argue that the relationship among the different methods, models, and representations of (...) protein structure is one of integrative pluralism. Our defence appeals to specific features of the complexity of the functional protein structure and to the partial character of representation in general. We present examples of integrative strategies in protein science. _1._ Introduction _2._ Partiality of Representation _3._ Protein Functional Complexity _4._ Modelling Protein Structure _4.1_ Integrating ab initio and experimental models _4.2_ Integrating multiple experimental models _5._ Conclusion. (shrink)

Using classical American pragmatism, the authors provide a philosophical framework for rethinking the nature of the corporation--how it is embedded in its natural, technological, cultural, and international environments, emphasizing throughout its pervasive relational and moral dimensions. They explore the relationship of this framework to other contemporary business ethics perspectives, as well as its implications for moral leadership in business and business education.

This paper studies the concept of form of life as central to ordinary language philosophy : philosophy of our language as spoken ; pronounced by a human voice within a form of life. Such an approach to Wittgenstein’s later philosophy shifts the question of the common use of language – central to Wittgenstein’s Investigations – to the definition of the subject as voice, and to the reinvention of subjectivity in language. The voice is both a subjective and common expression: it (...) is what makes it possible for my individual voice, or claim, to become shared and for our forms of life to be intertwined with a lifeform. (shrink)

Although high-performance human resource practices do not directly affect corporate social performance strengths, they do positively affect CSP strengths in companies that are highly innovative or have high levels of slack. High-performance human resource management practices also directly and negatively affect CSP concerns. Drawing on the resource-based view and using secondary data from an objective, third-party database, the authors develop and test hypotheses about how high-performance HRM affects a company’s CSP strengths and concerns. Findings suggest that HRM and innovation are (...) important capabilities because they create and enhance other capabilities. (shrink)

It has been claimed that ceteris paribus laws, rather than strict laws are the proper aim of the special sciences. This is so because the causal regularities found in these domains are exception-ridden, being contingent on the presence of the appropriate conditions and the absence of interfering factors. I argue that the ceteris paribus strategy obscures rather than illuminates the important similarities and differences between representations of causal regularities in the exact and inexact sciences. In particular, a detailed account of (...) the types and degrees of contingency found in the domain of biology permits a more adequate understanding of the relations among the sciences. (shrink)

In this paper I discuss recent debates concerning etiological theories of functions. I defend an etiological theory against two criticisms, namely the ability to account for malfunction, and the problem of structural doubles. I then consider the arguments provided by Bigelow and Pargetter (1987) for a more forward looking account of functions as propensities or dispositions. I argue that their approach fails to address the explanatory problematic for which etiological theories were developed.

Recently adopted health care practices and policies describe themselves as “patient-centered care.” The meaning of the term, however, remains contested and obscure. This paper offers a typology of “patient-centered care” models that aims to contribute to greater clarity about, continuing discussion of, and further advances in patient-centered care. The paper imposes an original analytic framework on extensive material covering mostly US health care and health policy topics over several decades. It finds that four models of patient-centered care emphasize: patients versus (...) their parts; patients versus providers; patients/providers/states versus “the system”; and patients and providers as persons. Each type is distinguishable along three dimensions: epistemological orientations, practical accommodations, and policy tools. Based on this analysis, the paper recommends that four questions be asked of any proposal that claims to provide patient-centered care: Is this care a means to an end or an end in itself? Are patients here subjects or objects? Are patients here individuals or aggregates? How do we know what patients want and need? The typology reveals that models are neither entirely compatible nor entirely incompatible and may be usefully combined in certain practices and policies. In other instances, internal contradictions may jeopardize the realization of coherent patient-centered care. (shrink)

In this article I consider the challenges for exporting causal knowledge raised by complex biological systems. In particular, James Woodward’s interventionist approach to causality identified three types of stability in causal explanation: invariance, modularity, and insensitivity. I consider an example of robust degeneracy in genetic regulatory networks and knockout experimental practice to pose methodological and conceptual questions for our understanding of causal explanation in biology. †To contact the author, please write to: Department of History and Philosophy of Science, University of (...) Pittsburgh, 1017 Cathedral of Learning, Pittsburgh, PA 15260; e‐mail: [email protected]. (shrink)

Unites George Herbert Mead and Maurice Merleau-Ponty in a shared rejection of substance philosophy as well as spectator theory of knowledge, in favor of a focus on the ultimacy of temporal process and the constitutive function of social praxis.

SummaryPhilosophic questions about the adequacy of our prevailing Western conceptions of rationality have emerged from the growing recognition that one cannot simply “add women” as objects of knowledge to the existing bodies of our social and natural knowledge. Recent research in psychology and in moral development theory suggests that our understandings of the rationality of human activity are distorted and obscured by systematically identifying as universally desireable, as Human goals, conceptions of the self, others, and the appropriate relationships between the (...) two which are distinctively masculine. The essay suggests some implications of these research findings for the ways philosophers think about “the problems of philosophy”, moral theory, the role of formality and abstractness, and the “rational reconstructions” of the history of science.RésuméDes questions philosophiques se sont posées, a propos de ľadéquation de nos conceptions occidentales courantes de la rationalité, du fait de la reconnaissance qu'on ne peut pas simplement ajouter les femmes comme objets de connaissance aux corpus existants de notre connais‐sance sociale et naturelle. Des recherches récentes en psychologie et en théorie du développement moral suggèrent que notre comprèhension de la rationalité de ľactivité humaine est déformee et obscurcie par une identification systématique, comme universellement désirables, comme buts de ľhumanité, des conceptions de soi, des autres et des relations entre les deux qui sont distincte‐ment masculines. Cet essai suggère quelques applications de ces resultats de recherche quant à la maniere dont les philosophes pensent les problèmes de la philosophies la morale, le rôle du formel et de ľabstrait et les reconstuctions rationnelles de ľhistoire de la science.ZusammenfassungPhilosophische Fragen ïber die Angemessenheit unserer vorherrschenden Auffassungen von Rationalität im Westen sind durch die wachsende Einsicht entstanden, dass man nicht einfach Frauen als Objekte dem bestehenden Korpus unserer Sozial‐ und Naturwissenschaften hinzufügen kann. Neuere Forschungen in Psychologie und Theorien der moralischen Entwicklung legen nahe, dass unser Verstandnis der Rationalität von menschlichen Handlungen dadurch verzerrl und verdunkelt wird, dass systematische Auffassungen vom Selbst, den andern und den unter ihnen angebrachten Beziehungen als allgemein wünschbare Ziele anerkannt werden, die spezi‐fisch männlich sind. Es werden einige Implikationen dieser Forschungen t'iir die Art, wie Philoso‐phen über die Probleme der Philosophie denken, aufgezeigt – u.a. in bezug auf die Theorie der Moral, die Rolle der Formalisierung und Abstraktion, und die rationalen Rekonstruktionen der Geschichte der Wissenschaft. (shrink)

I argue that diversity and pluralism are valuable not just for science but for philosophy of science. Given the partiality and perspectivism of representation, pluralism preserving integration can...

It has long been held that the structure of a protein is determined solely by the interactions of the atoms in the sequence of amino acids of which it is composed, and thus the stable, biologically functional conformation should be predictable by ab initio or de novo methods. However, except for small proteins, ab initio predictions have not been successful. We explain why this is the case and argue that the relationship among the different methods, models, and representations of protein (...) structure is one of integrative pluralism. Our defence appeals to specific features of the complexity of the functional protein structure and to the partial character of representation in general. We present examples of integrative strategies in protein science. 1. Introduction2. Partiality of Representation3. Protein Functional Complexity4. Modelling Protein Structure4.1 Integrating ab initio and experimental models4.2 Integrating multiple experimental models5. Conclusion. (shrink)

ABSTRACT Genevieve Lloyd argues that when we follow Spinoza in understanding reason as a part of nature, we gain new insights into the human condition. Specifically, we gain a new political insight: we should respond to cultural difference with a pluralist ethos. This is because there is no pure universal reason; human minds find their reason shaped differently by their various embodied social contexts. Furthermore, we can use the resources of the imagination to bring this ethos about. In my response, (...) I offer a friendly challenge to Lloyd’s characterisation of the lessons of Spinoza’s philosophy. I argue that Lloyd’s Spinoza remains excessively unpolitical, even in the moment that he is brought to bear on contemporary politics. An unpluralistic attitude may well be rationally inferior, but is it really explained by insufficient or inappropriate imagination? To the contrary, a properly Spinozist account of reason must include an account of the concrete determinants of reason’s imperfect realisation in the world. In Spinoza’s own oeuvre, this is carried out through an ever-increasing—and ever more sociological—interest in the political structures within which individual reason flourishes or withers. (shrink)

Some have suggested that Jon Stewart of The Daily Show with Jon Stewart (TDS) and Stephen Colbert of The Colbert Report (TCR) represent a new kind of journalist. We propose, rather, that Stewart and Colbert are imitators who do not fully inhabit the role of journalist. They are interesting because sometimes they do a better job performing the functions of journalism than journalists themselves. However, Stewart and Colbert do not share journalists' moral commitments. Therefore, their performances are neither motivated nor (...) constrained by these commitments. Using a virtue theory framework, we suggest that this distinction between journalists and their imitators is morally significant because it implies differences in the kinds of excellence these moral agents are pursuing in their work. Rather than evaluating the work of Colbert and Stewart in the role of journalists, we propose analyzing their contributions to media ethics in the role of media critics. (shrink)

ABSTRACT Recently, children’s books have used augmented reality as a resource, being called 4D books. Augmented reality allows the user to see through the world while interacting in real-time with images produced digitally, resulting in interactivity. The present study aims to introduce the results of a brief reflection on the illustrated book O reino encantado do pôneis 4D under the approach of the semiotics of culture, departing from the notion of semiosis and semiosphere. The semiosphere, drawn by Lotman (1990), in (...) analogy with the biosphere, can help understand the topology of the real and virtual worlds, referred to as the real subsemiosphere and virtual subsemiosphere, located in the interior of the broader semiosphere of the Brazilian culture. In 4D/Augmented reality books, the elements from the virtual subsemiosphere are placed into the real subsemiosphere, crossing their borders. (shrink)

According to a recent interpretive orthodoxy, Spinoza is a profoundly democratic theorist of state authority. I reject this orthodoxy. To be sure, for Spinoza, a political order succeeds in proportion as it harnesses the power of the people within it. However, Spinoza shows that political inclusion is only one possible strategy to this end; equally if not more useful is political exclusion, so long as it maintains what I call the depoliticised acquiescence of those excluded.

A philosophical exploration of the meaning and significance of friendship.This book explains the persistence of friendship today in the light of the history of philosophical approaches to the subject. It considers ideals of intimacy and fusion in the context of claims that such ideals are unrealistic and even dangerous. Cicero's scepticism about friendship in the public realm is compared with the Aristotelian view of friendship as a genuine political bond, and with Derrida's development of that view via an exploration of (...) Aristotle's alleged and provocative announcement 'O my friends, there is no friend'. Tensions between love and respect, identity and difference, a focus on the self and a focus on the other are closely examined.From Aristotle to contemporary theorists, the book explores the conditions that enable the development of self-understanding in friendship, the delicate and unstable pairing of concepts like inclination and duty and distinctions between self-love, self esteem and self-concern in relations between friends.Key Features* Recognition of the variety of the term 'friend' in the history of philosophy* The treatment of the tension between identity and difference in relations between friends* Discussion of the contribution of friendship to self-understanding. (shrink)

The ethics of care has contributed to modifying a dominant conception of ethics and changed the way we conceive vulnerability. It has introduced ethical stakes into politics, weakening, through its critique of theories of justice, the seemingly obvious link between an ethics of justice and political liberalism. However, care corresponds to a quite ordinary reality: the fact that people look after one another, take care of one another and thus are responsible. The aim of this paper is to connect the (...) ethics of care to the idea of the vulnerability of the human as it is developed in the moral philosophy inspired by Wittgenstein. (shrink)

The empirical-normative split in business ethics is another manifestation of the fact-value problem that has existed betweenscience and philosophy for several centuries. This paper explores classical American pragmatism’s understanding of the fact-valuedistinction, showing how it offers a different way of understanding the empirical business ethics–normative business ethics issue.Unfolding the pragmatic perspective on this issue involves a focus on its understanding of both the nature of empirical inquiry and thenature of normative inquiry.

Abstract:The new push to move political issue activity from the federal to the state and local levels—a new New Federalism—has implications for the ethical and political legitimacy of business political activity. While business political activity at the federal level may be both less costly and less risky than when action shifts to states or localities, at the state or local level it is likely to be more visible, and individual firms may be perceived to have more power. Increased corporate power (...) raises questions about the legitimacy of firm involvement in the political process at the state and local levels. The issue of legitimacy is viewed in the context of the literature on political subcultures being used to study state economic development. (shrink)

In the course of the last few decades, Bolzano has emerged as an important player in accounts of the history of philosophy. This should be no surprise. Few authors stand at a more central junction in the development of modern thought. Bolzano's contributions to logic and the theory of knowledge alone straddle three of the most important philosophical traditions of the 19th and 20th centuries: the Kantian school, the early phenomenological movement and what has come to be known as analytical (...) philosophy. This paper identifies three Bolzanian theoretical innovations that warrant his inclusion in the analytical tradition: the commitment to ‘logical realism’, the adoption of a substitutional procedure for the purpose of defining logical properties and a new theory of a priori cognition that presents itself as an alternative to Kant's. All three innovations concur to deliver what counts as the most important development of logic and its philosophy between Aristotle and Frege. In the final part of the paper, I defend Bolzano against a common objection and explain that these theoretical innovations are also supported by views on syntax, which though marginal are both workable and philosophically interesting. (shrink)

Entscheidungen der Therapiebegrenzung und in der Betreuung am Lebensende sind häufig komplex und von ethischen Problemen begleitet. Im Mittelpunkt der Untersuchung steht die entscheidende Frage, wie hilfreich existierende „Ethik-Richtlinien“, die eine ethische Orientierung bei solchen Entscheidungen geben sollen, in der klinischen Praxis tatsächlich sind. Die Frage, welchen Nutzen „Ethik-Richtlinien“ bei der Entscheidungsfindung haben oder haben können, wird hier exemplarisch an einem klinischen Fallbeispiel aus einer Ethik-Kooperationsstudie in der Intensivmedizin analysiert. Vergleichend werden hierzu „Ethik-Richtlinien“ aus Deutschland, der Schweiz und aus Großbritannien (...) herangezogen, die Gegenstand eines internationalen Projekts zur Analyse von Richtlinien waren. Die Möglichkeiten und Grenzen einer ethischen Orientierung an „Ethik-Richtlinien“ bei Entscheidungsproblemen der Therapiebegrenzung und in der Betreuung am Lebensende werden anhand der Fallstudie diskutiert und illustriert. Abschließend werden Schlussfolgerungen für die Entwicklung ethischer Richtlinien für die klinische Praxis formuliert. (shrink)