Reading the Shape of Nature vividly recounts the turbulent early history of the Museum of Comparative Zoology at Harvard and the contrasting careers of its founder Louis Agassiz and his son Alexander. Through the story of this institution and the individuals who formed it, Mary P. Winsor explores the conflicting forces that shaped systematics in the second half of the nineteenth century. Debates over the philosophical foundations of classification, details of taxonomic research, the young institution's financial struggles, and the (...) personalities of the men most deeply involved are all brought to life. In 1859, Louis Agassiz established the Museum of Comparative Zoology to house research on the ideal types that he believed were embodied in all living forms. Agassiz's vision arose from his insistence that the order inherent in the diversity of life reflected divine creation, not organic evolution. But the mortar of the new museum had scarcely dried when Darwin's Origin was published. By Louis Agassiz's death in 1873, even his former students, including his son Alexander, had defected to the evolutionist camp. Alexander, a self-made millionaire, succeeded his father as director and introduced a significantly different agenda for the museum. To trace Louis and Alexander's arguments and the style of science they established at the museum, Winsor uses many fascinating examples that even zoologists may find unfamiliar. The locus of all this activity, the museum building itself, tells its own story through a wonderful series of archival photographs. (shrink)

Children show increasing control of emotions and behavior during their early years. Our studies suggest a shift in control from the brain’s orienting network in infancy to the executive network by the age of 3—4 years. Our longitudinal study indicates that orienting influences both positive and negative affect, as measured by parent report in infancy. At 3—4 years of age, the dominant control of affect rests in a frontal brain network that involves the anterior cingulate gyrus. Connectivity of brain structures (...) also changes from infancy to toddlerhood. Early connectivity of parietal and frontal areas is important in orienting; later connectivity involves midfrontal and anterior cingulate areas related to executive attention and self-regulation. (shrink)

Developing and implementing artificial intelligence (AI) systems in an ethical manner faces several challenges specific to the kind of technology at hand, including ensuring that decision-making systems making use of machine learning are just, fair, and intelligible, and are aligned with our human values. Given that values vary across cultures, an additional ethical challenge is to ensure that these AI systems are not developed according to some unquestioned but questionable assumption of universal norms but are in fact compatible with the (...) societies in which they operate. This is particularly pertinent for AI research and implementation across Africa, a ground where AI systems are and will be used but also a place with a history of imposition of outside values. In this paper, we thus critically examine one proposal for ensuring that decision-making systems are just, fair, and intelligible—that we adopt a principle of explicability to generate specific recommendations—to assess whether the principle should be adopted in an African research context. We argue that a principle of explicability not only can contribute to responsible and thoughtful development of AI that is sensitive to African interests and values, but can also advance tackling some of the computational challenges in machine learning research. In this way, the motivation for ensuring that a machine learning-based system is just, fair, and intelligible is not only to meet ethical requirements, but also to make effective progress in the field itself. (shrink)

Personalised medicine has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells so as to make individualised treatment predictions. We compare this strategy to two main PM strategies—stratified medicine and (...) computational models. Drawing on epistemological work in the philosophy of medicine, we explain why these two methods, while powerful, are neither truly personalised nor, epistemologically speaking, novel strategies. Both are forms of correlational black box. We then argue that the iPSC models would count as a new kind of black box. They would not rely entirely on mechanistic knowledge, and they would utilise correlational evidence in a different way from other strategies—a way that would enable personalised predictions. In arguing that the iPSC models would present a novel method of gaining evidence for clinical practice, we provide an epistemic analysis that can help to inform the practical, regulatory, and ethical challenges of developing an iPSC system. (shrink)

A long-standing tradition presents economic activity in terms of the flow of fluids. This metaphor lies behind a small but influential practice of hydraulic modelling in economics. Yet turning the metaphor into a three-dimensional hydraulic model of the economic system entails making numerous and detailed commitments about the analogy between hydraulics and the economy. The most famous 3-D model in economics is probably the Phillips machine, the central object of this paper.

M. M. McCabe presents a selection of her essays which explore the Platonic method of conversation: how it may inform our understanding both of Plato and of his predecessors and successors, and how its centrality accounts for the connections between argument, knowledge, and virtue in the texts McCabe examines.

Conscientious objection has become a divisive topic in recent bioethics publications. Discussion has tended to frame the issue in terms of the rights of the healthcare professional versus the rights of the patient. However, a rights-based approach neglects the relational nature of conscience, and the impact that violating one’s conscience has on the care one provides. Using medical assistance in dying as a case study, we suggest that what has been lacking in the discussion of conscientious objection thus far is (...) a recognition and prioritising of the relational nature of ethical decision-making in healthcare and the negative consequences of moral distress that occur when healthcare professionals find themselves in situations in which they feel they cannot provide what they consider to be excellent care. We propose that policies that respect the relational conscience could benefit our healthcare institutions by minimising the negative impact of moral distress, improving communication among team members and fostering a culture of ethical awareness. Constructive responses to moral distress including relational cultivation of moral resilience are urged. (shrink)

Bruno Latour, as part of his advocacy of science studies urges us to move beyond what he calls ‘the Modernist Settlement’ that, among other things, separated science from politics and subject from object. As part of this project he has frequently called for the abolition of epistemology, including quite specifically the historical epistemology/epistemological history of Gaston Bachelard and Georges Canguilhem. Pierre Bourdieu, on the other hand, deploys the resources of historical epistemology, to dismiss Latour’s science studies. After examining the charges (...) against historical epistemology and their rebuttal, I rule in favor of the defense. However, I also suggest that Latour raises genuine concerns about how to equip ourselves to tackle problems such as those associated with climate change; these are problems that require engagement with the politics of nature, with the politics of the sciences of nature and with the epistemological challenges associated with the need to deploy multiple disciplines in the service of complex, practical, policy-relevant problem solving. (shrink)

In the preface to the Principia (1687) Newton famously states that “geometry is founded on mechanical practice.” Several commentators have taken this and similar remarks as an indication that Newton was firmly situated in the constructivist tradition of geometry that was prevalent in the seventeenth century. By drawing on a selection of Newton's unpublished texts, I hope to show the faults of such an interpretation. In these texts, Newton not only rejects the constructivism that took its birth in Descartes's Géométrie (...) (1637); he also presents the science of geometry as being more powerful than his Principia remarks may lead us to believe. (shrink)

This paper seeks to examine the plausibility of the concept of ‘Civic Friendship’ as a philosophical model for a conceptualisation of ‘belonging’. Such a concept, would hold enormous interest for educators in enabling the identification of particular virtues, attitudes and values that would need to be taught and nurtured to enable the civic relationship to be passed on from generation to generation. I consider both of the standard arguments for civic friendship: that it can be understood within the Aristotelian typology (...) as either a form of utility friendship or as a form of virtue friendship. I argue that civic friendship may not be the most appropriate model and that attempts to resolve the problems through looking on it as a political metaphor leave it unable to fulfil the function for which it was originally designed in Ancient Greece. Finally, I emphasize the need to carefully consider which particular metaphors we choose for civic relationships and how we subsequently use them. (shrink)

St. Augustine of Hippo wrote the ’De Trinitate’ to explain to critics of the Nicene Creed how the Christian doctrine of the divinity and coequality of Father, Son, and Holy Spirit is present in Scripture. He also wanted to convince philosophers that Christ is the Wisdom they sought. Augustine’s third purpose was to correlate the biblical truth that all human persons are created to image God, a Trinity, a communion of love, with the first two Commandments of the Old and (...) New Testaments. Augustine succeeded in showing the need for combining faith and reason for a greater understanding of Scripture as well as for a greater understanding of the true nature and destiny of human persons. Augustine emphasized the scriptural revelation of God as Father, Son, and Holy Spirit, and used reason to convince philosophers that the one and three-Personed God is philosophically and logically defensible. He concluded that the likeness of human persons to Christ and to the Trinity is accomplished not onl. (shrink)

In C.S. Lewis's science fiction parable Perelandra was a planet which had no solid ground. At all times the floating landscape was continually swirling and moving, chasms would appear where a minute before there had been safe standing. The rational beings who lived there hopped nimbly on to another little island when the one on which they stood disappeared under their feet. They were used to it and took it for granted that nothing was certain. The visitor from our planet (...) had to learn a completely new way of existence. But where did he get his idea of certainty in a fixed environment? It is more plausible that uncertainty is normal and the whole idea of certainty an illusion. Today gives an opportunity to reflect on how people deal with skepticism, doubt and uncertainty.The questions apply to a current debate in the UK on risk. Opinion polls constantly reveal that the public lacks trust in government, and particularly it does not trust the government to reveal the information needed to assess important risks. From which the risk analysts conclude that the government should grant access to information more freely and encourage enquiry. They believe that openness would foster a better understanding on the part of the public which at present does not know what to believe. More information would create certainty, more certainty and the public would trust its spokesmen, unreasonable fears would be calmed. This is the advice of an expert enquiry.Certainty is not a mood, or a feeling, it is an institution: this is my thesis. Certainty is only possible because doubt is blocked institutionally: most individual decisions about risk are taken under pressure from institutions. If we recognize more uncertainty now, it will be because of things that have happened to the institutional underpinning of our beliefs. And that is what we ought to be studying. In my student days the hottest controversies in anthropology were about why `other people' — that is people not living in advanced capitalist society — had certainty about their absurd beliefs.When trying to explain their misfortunes, why did they neglect the physical and scientific evidence, and draw instead on their beliefs in spirits, magic, and taboos? How could they be so obstinate in error? Anthropologists spent their energies on defending the allegedly irrational beliefs of other people, and I shall continue the tradition. (shrink)

Fifteen to twenty years ago one might have been forgiven for thinking that both the philosophy and history of science constituted specialized academic backwaters, far removed from debates in the forefront of either philosophic or public attention. But times have changed; science and technology have in many ways and in many guises become central foci of public debate, whether through concern over nuclear safety, the massive price to be paid for continued research in areas such as high energy physics, the (...) cost of high technology medicine, the spectre of genetic engineering, or the wonders of information processing and the computer revolution. At the same time that there is public questioning of the authority of expert scientific pronouncements and debate about the wisdom of courses of action proposed in the name of technology and progress, there is political pressure to direct eduction in an increasingly scientific and technological direction. But even so, in this country, the history and philosophy of science remain peripheral disciplines, not only in relation to the total academic scene but even in relation to philosophy, which is itself being academically marginalized. (shrink)

Cover -- Half Title -- Title Page -- Copyright Page -- Contents -- Notes on Contributors -- Introduction to the Series -- Acknowledgements -- 1. Introduction -- 2. Oral History as Genre -- 3. Silences -- 4. A Brazilian Worker's Autobiography in an Unexpected Form -- 5. Family Fables -- 6. Anecdote as Narrative Resource in Working-Class Life Stories -- 7. My Life as Consumer -- 8. Distant Homes, Our Genre -- 9. The Oral History Interview in a Cross-Cultural Setting (...) -- 10. In the Archieve, In the Field -- 11. Sharing and Resharing Life Stories -- Raphael Samuel -- Raphael Samuel -- A Call for Contributors -- Index. (shrink)

This Element describes the main theories that guide contemporary research in cognitive development along with research discoveries in several important cognitive abilities: attention, language, social cognition, memory, metacognition and executive function, and problem solving and reasoning. Biological and social contributions are considered side-by-side, and cultural contributions are highlighted. As children participate in social interactions and learn to use cultural symbols and tools to organize and support their thinking, the behaviors and understandings of the social community and the culture more broadly (...) become an integral part of children's thoughts and actions. Culture, the natural ecological setting or habitat of human beings, plays a significant role by providing support and direction for cognitive development. Without the capacity to learn socially, human cognition would be markedly different from what it is today. (shrink)

The Western cultural consensus based on the ideas of free markets and individualism has led many social scientists to consider poverty as a personal experience, a deprivation of material things, and a failure of just distribution. Mary Douglas and Steven Ney find this dominant tradition of social thought about poverty and well-being to be full of contradictions. They argue that the root cause is the impoverished idea of the human person inherited through two centuries of intellectual history, and that (...) two principles, the idea of the solipsist self and the idea of objectivity, cause most of the contradictions. Douglas and Ney state that Economic Man, from its semitechnical niche in eighteenth-century economic theory, has taken over the realms of psychology, consumption, public assistance, political science, and philosophy. They say that by distorting the statistical data presented for policy analysis, the ideas of the solipsist self and objectivity indeed often protect a political bias. The authors propose to correct this by revising the current model of the person. Taking cultural bias into account and giving full play to political dissent, they restore the "persons" who have been missing from the social science debates. Drawing from anthropology, economics, political science, and sociology, the authors set forth a fundamental critique of the social sciences. Their book will find a wide audience among social scientists and will also interest anyone engaged in current discussions of poverty. This book is a copublication with the Russell Sage Foundation. (shrink)

Universals are a class of mind independent entities, usually contrasted with individuals, postulated to ground and explain relations of qualitative identity and resemblance among individuals. Individuals are said to be similar in virtue of sharing universals. An apple and a ruby are both red, for example, and their common redness results from sharing a universal. If they are both red at the same time, the universal, red, must be in two places at once. This makes universals quite different from individuals, (...) and controversial. (shrink)

This article offers a new hypothesis regarding Judg. 11.39d-40, a reference to an otherwise unknown festival celebrated by the ‘daughters of Israel’ in memory of the sacrifice of Jepththah’s daughter. After a survey of feminist and non-feminist speculations as to the nature of the festival, evidence from Greek heroine cults in which daughters are sacrificed for the good of the state is adduced as the closest parallel in ancient literature. The article concludes with some feminist theological considerations occasioned by the (...) patriotic and military nature of the festival. (shrink)

This article is concerned with the construction of feminist literary studies in the last twenty years and points out how we have created a literary history which is both selective and schematic. It suggests that we should be more critically aware of what we are constructing, how we are constructing it and of the political consequences of those constructs. It stresses three critical modes which might help us to complicate our history: a greater awareness of institutional contexts, a concern with (...) empirical detail, and an ongoing analysis of the cultural and political significance of feminist literary practice. This article briefly applies these critical modes in a survey of eleven introductions to feminist literary studies – introductions which feature frequently and influentially in the teaching situation. The final section focuses on the key problem of inclusion and exclusion. Considering arguments from Third World feminism and postmodernist feminism, the study concludes that white, academic feminists should confront the privilege of their own inclusion as a necessary spur to political action. (shrink)

This paper is part of a cluster of issues around reconciliation on which I have been working. I begin with the tension between the fact that reconciliation is an unpopular concept in feminist theology, yet in contexts of conflict is the deepest longing as well as a cherished Christian ideal. By focusing on post-genocide Rwanda I am opening up key issues. I then focus on the difficulties associated with `reconciliation' beginning with the fear that it may involve giving up on (...) structural justice. Feminist theology's problems with the concept are explored before re-envisioning the death of Jesus in terms of life-giving love and affirmation of life which is the suggested re-interpretation of sacrifice. This brings us into a meta-patriarchal world where symbols of flourishing replace patriarchal symbols of violence. Reconciliation then is both the goal of healed creation and the path towards it. (shrink)

In this exploratory study, we look at the professed values that people have, and their performance in a negotiation. We found relations between Schwartz values and conflict handling behaviors, and distributive, integrative, and compatible negotiation outcomes in a controlled environment using Actor-Partner Interdependence Model (APIM) analysis.

Shaman Pharmaceuticals seeks a cure for what ails the drug industry.