This book is an excellent book on business ethics and will be an invaluable resource for all readers who are keen to learn about the business ethics and key characteristics of a successful company. It focuses on the case study of a global company, Johnson & Johnson (J&J), which oversees more than 250 operating units throughout the world. Through extensive interviews with top executives at J&J's headquarters, including Masami Atarashi and Mitsuo Hirose and attending workshops, Prof Hiroo Takahashi acquired (...) an in-depth understanding of the management style of J&J, grasped the company's ethics and the code of business conduct which is shared by J&J's members throughout the world. (shrink)

東アジア世界のなかで日本思想史はいかに構築できるか...古代から現代までを網羅した概説、待望の増補版。.

The nonobese diabetic (NOD) mouse spontaneously develops an autoimmune diabetes that shares many immunogenetic features with human insulin-dependent diabetes mellitus (IDDM), type 1 diabetes. The mononuclear cell infiltrates in the islet, which results in the development of insulitis (a prerequisite step for the development of diabetes) are primarily composed of T cells. It is now well accepted that these T cells play important roles in initiating and propagating an autoimmune process, which in turn destroys insulin-producing islet β cells in the (...) pancreas. T cells are subdivided into CD4+ helper T cells and CD8+ cytotoxic T cells. CD4+ T cells are further subdivided into Th1 and Th2 cells based on profiles of cytokine production, and these two T-cell populations counterregulate each other. Because many autoimmune diseases are Th1 T-cell mediated, current studies have focused on manipulating the Th1/Th2 imbalance to suppress the autoimmune process in the NOD model. Furthermore, the incidence of disease is much higher in females than that in males, suggesting an involvement of sex-steroid hormones in the development of diabetes. Understanding insights of the mechanism of immune-mediated islet cell destruction and the interaction between the immune and the neuroendocrine system may, therefore, provide new therapeutic means of preventing this chronic debilitating disease. BioEssays 20:750–757, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

In this essay I will put forward an account of the emotion of shame that draws from Bernard Williams’ groundbreaking work on Shame and Necessity. The main novelty will be a distinction between two senses of shame, “basic shame” and “complex shame”. Basic shame is related to what Williams refers to as a “loss of power” in relation to others that can be real or imaginary spectators and is a sense of diminishment towards those others. Complex shame, in turn, appears (...) when this diminishment is felt in relation to an “internalised other” that embodies the values she recognises as her own as well as other values she respects. Borrowing a page from Cheshire Calhoun, I argue that many accounts of shame face what I call the “challenge of unrespected judgments”: people are vulnerable to shame even when they do not endorse or respect the judgments of those shaming them. I claim that the proposed Williamsian account of the emotion can dissolve the challenge, because for one to feel basic shame there is no need for any further attitude of the ashamed person towards the shamer besides a sense of diminishment caused by the perception of loss of power. In addition to that, oppression can influence the internalised other of marginalised people in a way that makes them vulnerable to complex shame. I will conclude with some brief remarks about how moral education in the Aristotelian sense can help us to deal with the morally problematic instances of shame. (shrink)

PurposeThis paper aims to deal with the attitudes towards and social impact of Edward Snowden’s revelations in Japan, taking the Japanese socio-cultural and political environment surrounding privacy and state surveillance into account.Design/methodology/approachA questionnaire survey of 1,820 university students and semi-structured follow-up interviews with 56 respondents were conducted, in addition to reviews of the literature on privacy and state surveillance in Japan. The outcomes of the survey were statistically analysed, and qualitative analyses of the interview results were also performed.FindingsSnowden’s revelations have (...) had little influence over Japanese youngsters’ attitudes towards privacy and state surveillance, mainly due to their low level of awareness of the revelations and high level of confidence in government agencies.Practical implicationsThe study results imply a need for reviewing educational programmes for civic education in lower and upper secondary education.Social implicationsThe results of this study based on a large-scale questionnaire survey indicate an urgent necessity for providing Japanese youngsters with opportunities to learn more about privacy, liberty, individual autonomy and national security.Originality/valueThis study is the first attempt to investigate the social impact of Snowden’s revelations on Japanese youngsters’ attitudes towards privacy and state surveillance as part of cross-cultural analyses between eight countries. (shrink)

Discovery of representative Web pages regarding specific topics is important for assisting users' information retrieval from the Web. Researches on Web structure mining, whose goals are to discover or to rank important Web pages based on the graph structure of hyperlinks, have been very active recently. A complete bipartite of Web graph, which is composed of centers (containing useful information regarding specific topic) and fans (containing hyperlinks to centers), can be regarded as a Web community sharing a common interest. Although (...) Murata's method for discovering Web communities is a simple method for finding related Web pages, it has the following weaknesses: (1) since the number of centers increases monotonously, pages irrelevant to the members of Web communities may be added in the process of discovery, and (2) since the number of fans decreases monotonously according as the number of centers increases, the method may suffer topic drift. This paper describes an improved method for refining Web communities in order to acquire representative Web pages of the topics of input Web communities. The method is based on the assumption that most of the fans contain hyperlinks pointing to representative pages regarding their topic, and that hyperlinks to the pages of the same quality often co-occur. In our new method, both fans and centers are renewed iteratively by the result of the majority vote of the members of previous Web community. Results of our experiments show that the new method has abilities of finding desirable pages for several topics. (shrink)

Through expanded access protocols, the Food and Drug Administration (FDA) allows patients with serious or immediately life-threatening diseases access to experimental drugs outside the clinical trial setting when no satisfactory alternative treatment is available. While the FDA has established a mechanism for providing patients with unapproved drug access, the regulations do not require the pharmaceutical company to provide the drug. The drug company’s permission to use its experimental drug is a necessary prerequisite to using the FDA’s expanded access mechanism. Increasingly, (...) drug companies are coming under scrutiny regarding the programs governing that decision-making power. Historically, disclosing whether a company has an expanded access program, and whether or how it would respond to an expanded access request, has been left to discretion of the drug companies themselves. Few manufacturers publish adequate expanded access protocols. As a result, patients were provided with little insight into how companies evaluate expanded access requests and are naturally skeptical as to the ethical integrity of the process. The recently passed 21st Century Cures Act changes that practice by requiring drug companies to have, and make publically available, their expanded access procedures including criteria for evaluating and responding to patient requests. In this article, we contend that complying with the new transparency provisions will require drug companies to respond to several unresolved expanded access issues. Namely, how to reconcile a patient’s desire to access lifesaving experimental therapies alongside the company and society’s interest in the efficient development of new drugs. Even more challenging, how can companies devise practices for evaluating and processing expanded access requests that also fairly and equitably acknowledge those concerns? In addressing these questions, this article explores the legal, regulatory, business, and societal influences that have shaped expanded access policies and practices. From there, we provide companies a framework that balances appropriately the desires of individuals and gaining the requisite approvals ensure access not just for one person but for society. (shrink)

Volume 15, Issue 4, December 2024, Page 573-586.

Joseph Raz intended to clarify the ‘boundary between my life as I lead it, and what happens to me in my life’. Such boundary is given by my relationship with the reasons I believe that I have. My aim is to present a broadly Razian account of what it means to be active in our lives. The basic idea is that I can see myself as active insofar as I can make sense of my own life in terms of reasons (...) that I believe that apply to me. I will also engage with Harry Frankfurt’s criticisms. Firstly, Frankfurt believed that the Razian account is implausible because the idea of choosing an action without having reasons makes sense. Secondly, being active, says Frankfurt, is less about being in touch with our perceived reasons and more about what he calls wholeheartedness. I will defend the account against both kinds of criticism. (shrink)

Purpose This paper aims to introduce a cross-cultural study of the views and implications of Snowden’s revelations about NSA/GCHQ surveillance practices, undertaken through surveys administered in eight countries. The aims and academic and social significance are explained, and justification is offered for the methods used. Design/methodology/approach Pilot surveys were deployed in two countries, following which revised versions were deployed in eight countries. Quantitative analysis of suitable answer sets and quantitative analysis were performed. Findings Through the pilot survey studies conducted in (...) Japan and Spain, the academic significance and meaningfulness, as well as social significance of the project, were confirmed. Practical implications The results of the cross-cultural study are expected to contribute not only to the advance of surveillance study but also to the enhancement of ordinary, non-technical people’s awareness of state surveillance and their proactive approach to protecting their own rights and dignity from covert intrusion by government agencies. Originality/value This paper clarifies the importance and methodologies of investigating the social impact of Snowden’s revelations on youngsters’ attitudes toward privacy and state surveillance in a cross-cultural analysis framework. Although a few other studies have assessed the impact of Snowden’s revelations, these have mostly focussed on the USA, so this is the only study to date considering that impact on a broad international scale, using highly similar surveys to ensure comparability. (shrink)

Purpose This study aims to investigate how Snowden’s revelations are viewed by young people in the People’s Republic of China and Taiwan through questionnaire surveys of and follow-up interviews with university students in the two countries, taking into account the histories and current status of state surveillance in these countries and the current complicated and delicate cross-strait relationships. Design/methodology/approach Questionnaire surveys of 315 PRC and 111 Taiwanese university students and semi-structured follow-up interviews with 16 master’s course students from the PRC (...) and one from Taiwan were conducted, in addition to reviews of the literature on privacy and state surveillance in the PRC and Taiwan. The outcomes of the survey were statistically analysed and qualitative analyses of the interview results were also performed. Findings Youngsters living in the PRC had greater interest in and more knowledge about Snowden’s revelations than those living in Taiwan, and the revelations were positively evaluated in both countries as serving public interest. However, PRC students indicated they were less likely to emulate Snowden than those from Taiwan did. Originality/value This study is the first attempt to investigate the social impact of Snowden’s revelations on PRC and Taiwanese youngsters’ attitudes towards privacy and state surveillance as part of cross-cultural analyses between eight countries. (shrink)

PurposeThe purpose of this paper is to reconsider the concept of the right to information privacy and to propose, from a Japanese perspective, a revised conception of this right that is suitable for the modern information society.Design/methodology/approachFirst, the concept of privacy and personal information protection in the information society is briefly explained. After that, confused situations in Japan caused by the enforcement of Act on the Protection of Personal Information are described followed by the analysis of the Japanese socio‐cultural circumstances (...) surrounding privacy. Based on these, the effectiveness of the concept of the right to information privacy in the Japanese socio‐cultural and economic context is examined and the need to rethink the concept of the right to information privacy discussed. Finally, a revised conception of the right is proposed.FindingsIn view of the circumstances in Japan, the concept of the right to information privacy, defined as “an individual's right to control the circulation of information relating to him/herself”, as well as the Organisation for Economic Co‐operation and Development's eight principles already become outdated in today's sophisticated information‐communication society. There is a need to control/restrict use of personal information so that individuals' autonomy and freedom is ensured in the current situation and to revise the concept of the right to information privacy based on this idea.Originality/valueThis paper proposes a revision of the concept of the right to information privacy focused on control of, not access to, use of personal information. The revised concept is defined so that individuals' autonomy and freedom is ensured even in the “informational transparent” society. (shrink)

In this article I want to focus on a specific function that promises fulfil in our lives: their role as a way of shaping our character. To make my case, I will present an account of truth-telling based on Bernard Williams’ work on genealogy and on the virtues of truth. This account will highlight how our selves (or characters) are not static entities in time, that they are not immediately transparent to us. Nonetheless, we seem to have what I call (...) a drive to be someone, to have a character. We need ways to ‘steady the mind’, that is, ways of shaping our selves to whom we are or want to be. The argument I will put forward is that promises are one of the resources we have for doing so. By making promises, we commit ourselves to acting in a certain way and by doing that we also shape our selves. The argument will help us to answer some philosophical challenges raised against promises, notably about their rationality and about their relationship with vows and resolutions. Additionally, it will impact our thinking about contract law. What emerges from this article is an account of an important role played by promises that has been often neglected by the literature. (shrink)

This chapter, which describes the spatiality of conscious phenomena, such as colours and sounds, addresses James Gibson’s ecological approach to confirm and develop further the Husserlian phenomenological view of colours and sounds. The ecological approach to perception could be regarded as an attempt to undertake empirical research corresponding to the phenomenological insight of perception. In this context, in addition to the Husserlian concept of “adumbration” and the Gibsonian concept of “ecological optics,” the differentiation of various modes of colour appearances, which (...) David Katz explicated, is focused on, developed and applied further to the phenomena of sounds. On the basis of these discussions, the multi-dimensional character of colours and sounds are explicated, and traditional views on colours and sounds, which neglect this character, are criticized. The concept of multi-dimensionality discovers the remarkable diversity of the world of colours and sounds, which demonstrate the diversity and multiple dimensionality of the field of consciousness. (shrink)

One of the most important tasks of engineering ethics is to give engineers the tools required to act ethically to prevent possible disastrous accidents which could result from engineers’ decisions and actions. The space shuttle Challenger disaster is referred to as a typical case in almost every textbook. This case is seen as one from which engineers can learn important lessons, as it shows impressively how engineers should act as professionals, to prevent accidents. The Columbia disaster came seventeen years later (...) in 2003. According to the report of the Columbia accident investigation board, the main cause of the accident was not individual actions which violated certain safety rules but rather was to be found in the history and culture of NASA. A culture is seen as one which desensitizedmanagers and engineers to potential hazards as they dealt with problems of uncertainty. This view of the disaster is based on Dian Vaughan’s analysis of the Challenger disaster, where inherent organizational factors and culture within NASA had been highlighted as contributing to the disaster. Based on the insightful analysis of the Columbia report and the work of Diane Vaughan, we search for an alternative view of engineering ethics. We focus on the inherent uncertainty of engineers’ work with respect to hazard precaution. We discuss claims that the concept of professional responsibility, which plays a central role in orthodox engineering ethics, is too narrow and that we need a broader and more fundamental concept of responsibility. Responsibility which should be attributed to every person related to an organization and therefore given the range of responsible persons, governments, managers, engineers, etc. might be called “civic virtue”. Only on the basis of this broad concept of responsibility of civic virtue, we can find a possible way to prevent disasters and reduce the hazards that seem to be inseparable part of the use of complex technological systems. (shrink)

The construction of a secure and safe society using information and communication technology is recognised as an urgent issue in Japan. This recognition is based on public fear about crime related to manufactured risk caused by modernisation or industrial civilisation. This fear has created a social atmosphere that has led to the rapid development and implementation of security systems using ICT, such as security cameras, smart IC cards and mobile phones, to establish security and safety in Japanese society. However, the (...) never-ending quest for social security and safety with ICT will inevitably cause further manufactured risk, which could lead to serious problems in the future. We have to recognise such risk and control it appropriately. (shrink)

Bien que John Stuart Mill et Jeremy Bentham aient été considérés comme d’illustres exemples de « Philosophes radicaux », leurs exigences en matière de réforme sociale et politique étaient basées sur des points de vue différents. Comparée à celle de Bentham, l’analyse de Mill concernant le principe d’utilité et de démocratie représentative présente certains traits « perfectionnistes » et « élitistes ». La présente étude se propose d’examiner ceci à la lumière de la réception et de la réponse de Mill (...) aux idées de Bentham sur la politique. Bien que Mill fût, en partie, un partisan enthousiaste de Bentham, et qu’il lui attribuât le mérite de promouvoir les réformes juridiques et politiques, il semble avoir commencé, à partir de 1833, à évaluer ouvertement Bentham de façon critique. Ceci peut être perçu dans ses discussions et sa relation intellectuelle avec George Grote, qui était aussi un politicien et un historien utilitariste. L’accent mis par Mill sur le rôle essentiel de « l’éducation sociale du peuple » dans la promotion de l’esprit public fut développé dans des dialogues avec Grote et l’examen de ses études historiques. La présente étude conclut que Grote fit preuve de plus de sympathie envers Bentham que Mill, dans l’approche théorique aussi bien que dans l’approche pratique. Bien que tous les trois fussent vraiment dévoués à la même cause radicale, ils avaient toutefois des visions différentes de la crise de la démocratie parlementaire. L’examen du contexte de sa relation intellectuelle avec Grote fournit l’une des sources permettant de comprendre le défi jeté par Mill aux idées de Bentham relatives à la réforme politique. (shrink)

Once I’ve heard a joke about legal academia, and given that this was a very good joke, it was also very close to reality. This is how it went: ‘well, if you want to be successful in the Anglo-Ameri...

This paper aims to examine the evolution of Japanese studies of international relations since the end of World War II. In so doing, in particular, this paper first looks at the dominant trends and characteristics of Japanese scholarship in this field, and, second, the correlations between the scholarship and Japan's experiences in real international relations. In discussing the evolution of Japanese studies of international relations, I shall divide the years since 1945 into three separate periods: (1) 194589, and (3) 1990 (...) and after. Then, taking the current US–Japan relationship as a case study, I will examine the contemporary characteristics of Japanese scholarship in this field. (shrink)