Microbes in the gastrointestinal tract are under selective pressure to manipulate host eating behavior to increase their fitness, sometimes at the expense of host fitness. Microbes may do this through two potential strategies: (i) generating cravings for foods that they specialize on or foods that suppress their competitors, or (ii) inducing dysphoria until we eat foods that enhance their fitness. We review several potential mechanisms for microbial control over eating behavior including microbial influence on reward and satiety pathways, production of (...) toxins that alter mood, changes to receptors including taste receptors, and hijacking of the vagus nerve, the neural axis between the gut and the brain. We also review the evidence for alternative explanations for cravings and unhealthy eating behavior. Because microbiota are easily manipulatable by prebiotics, probiotics, antibiotics, fecal transplants, and dietary changes, altering our microbiota offers a tractable approach to otherwise intractable problems of obesity and unhealthy eating. (shrink)

The aim of this paper is to begin developing a version of Gualtiero Piccinini’s mechanistic account of computation that does not need to appeal to any notion of proper (or teleological) functions. The motivation for doing so is a general concern about the role played by proper functions in Piccinini’s account, which will be evaluated in the first part of the paper. I will then propose a potential alternative approach, where computing mechanisms are understood in terms of Carl Craver’s perspectival (...) account of mechanistic functions. According to this approach, the mechanistic function of ‘performing a computation’ can only be attributed relative to an explanatory perspective, but such attributions are nonetheless constrained by the underlying physical structure of the system in question, thus avoiding unlimited pancomputationalism. If successful, this approach would carry with it fewer controversial assumptions than Piccinini’s original account, which requires a robust understanding of proper functions. Insofar as there are outstanding concerns about the status of proper functions, this approach would therefore be more generally acceptable. (shrink)

Judgments concerning animals have arisen across a variety of established practice areas. There is, however, no publicly available repository of judgments concerning the emerging practice area of animal protection law. This has hindered the identification of individual animal protection law judgments and comprehension of the scale of animal protection law made by courts. Thus, we detail the creation of an initial animal protection law repository using natural language processing and machine learning techniques. This involved domain expert classification of 500 judgments (...) according to whether or not they were concerned with animal protection law. 400 of these judgments were used to train various models, each of which was used to predict the classification of the remaining 100 judgments. The predictions of each model were superior to a baseline measure intended to mimic current searching practice, with the best performing model being a support vector machine (SVM) approach that classified judgments according to term frequency—inverse document frequency (TF-IDF) values. Investigation of this model consisted of considering its most influential features and conducting an error analysis of all incorrectly predicted judgments. This showed the features indicative of animal protection law judgments to include terms such as ‘welfare’, ‘hunt’ and ‘cull’, and that incorrectly predicted judgments were often deemed marginal decisions by the domain expert. The TF-IDF SVM was then used to classify non-labelled judgments, resulting in an initial animal protection law repository. Inspection of this repository suggested that there were 175 animal protection judgments between January 2000 and December 2020 from the Privy Council, House of Lords, Supreme Court and upper England and Wales courts. (shrink)

"Act" or "Actuality" traduces two words coined by Aristotle: energeia and entelecheia. The first meaning of energeia is movement (kinesis). The second meaning designs the end of movement: form, substance (ousia), essence. Here entelecheia is brought to design that final state in which things reach their end and perfection. The third meaning or application of ener-geia, and derivately of entelecheia, is operation, action, function (ergon).

One of the central issues dividing proponents of metaphysical interpretations of transcendental idealism concerns Kant’s views on the distinctness of things in themselves and appearances. Proponents of metaphysical one-object interpretations claim that things in themselves and appearances are related by some kind of one-object grounding relation, through which the grounding and grounded relata are different aspects of the same object. Proponents of metaphysical two-object interpretations, by contrast, claim that things in themselves and appearances are related by some kind of two-object (...) grounding relation, through which the grounding and grounded relata involve distinct objects. By way of investigating Kant’s overarching account of grounding, I will argue that the most plausible metaphysical interpretation of transcendental idealism is one on which we can know that there are things in themselves grounding appearances, but not which specific kind of one- or two-object grounding relation obtain between them. Our ignorance of things in themselves therefore extends to their distinctness from appearances — pace both metaphysical one-object interpretations and metaphysical two-object interpretations. (shrink)

The indispensability argument is a method for showing that abstract mathematical objects exist. Various versions of this argument have been proposed. Lately, commentators seem to have agreed that a holistic indispensability argument will not work, and that an explanatory indispensability argument is the best candidate. In this paper I argue that the dominant reasons for rejecting the holistic indispensability argument are mistaken. This is largely due to an overestimation of the consequences that follow from evidential holism. Nevertheless, the holistic indispensability (...) argument should be rejected, but for a different reason —in order that an indispensability argument relying on holism can work, it must invoke an unmotivated version of evidential holism. Such an argument will be unsound. Correcting the argument with a proper construal of evidential holism means that it can no longer deliver mathematical Platonism as a conclusion: such an argument for Platonism will be invalid. I then show how the reasons for rejecting the holistic indispensability argument importantly constrain what kind of account of explanation will be permissible in explanatory versions. (shrink)

The distinction between explanation and understanding was foundational to Jaspers’ ‘phenomenological’ approach to psychiatry. It makes sense that those now calling for a phenomenological approach to psychiatry would look to Jaspers for inspiration, and that in doing so, they would take up this distinction. However, I argue that it is and was a mistake to use the distinction in work on psychiatry: adhering to the distinction now would undermine, rather than support, the goals of those advocating a phenomenological approach to (...) psychiatry; furthermore, if the distinction had been adhered to, then contemporary psychiatry and its patients would be worse off. (shrink)

Content note: This paper discusses rape throughout.Abstract. In this paper, I consider arguments in favor of jury trials. While I find these generally persuasive, I argue that there can be cases where juries are not fit for purpose. In those cases, I argue that they should be replaced by judge-only trials. In doing so, I propose a framework for determining whether a type of case is unsuitable for jury trials. Partly in response to low conviction rates, there have been recent (...) suggestions that rape trials should be conducted without juries. I suggest that there is strong evidence that these offences qualify under the criteria I have described. As a result, I argue that judge-only trials should be adopted for trying rape cases. (shrink)

Mensch and Barge in their interpretation of Alasdair MacIntyre’s critique of genealogical ethics as a basis of ethical weakness in the emerging field of “leadership-as-practice,” suggest that L-A-P is lacking in ethical grounding especially because of its relativist philosophy. I address this valid ethical concern in L-A-P theory by arguing that there is a form of realism in Nietzchean axiology and that the dialogic potentialities in material-social interactions may offer a greater capacity for ethical reflexivity than a reliance on rules.

Several philosophers have defended versions of Minimax Complaint, or MC. According to MC, other things equal, we should act in the way that minimises the strongest individual complaint. In this paper, I argue that MC must be rejected because it has implausible implications in certain cases involving risk. In these cases, we can apply MC either ex ante, by focusing on the complaints that could be made based on the prospects that an act gives to people, or ex post, by (...) focusing on the complaints that could be made based on the actual results that an act has for people. I argue that MC has implausible implications either way. I then defend a view on which, other things equal, we should act in the way that minimizes the sum of complaints. (shrink)

In his recent book, A Frightening Love: Recasting the Problem of Evil, Andrew Gleeson challenges a certain conception of justification assumed in mainstream analytic philosophy and argues that analytic philosophy is ill-suited to deal with the most pressing, existential, form of the problem of evil. In this article I examine some aspects of that challenge.

The United States is on a path of increasing social conflict, accentuated class, and racial inequalities. Based on a belief that change can be brought about by citizen action, this volume argues that such action can be assisted by what the authors call "liberation sociology"--A tool for the increase of democratic participation in the production and implementation of knowledge.

Concussive injuries to the head and brain are relatively common in the National Football League. This is not news, since the issue has been covered in many articles in the popular press and many news specials on television. As an NFL offensive lineman for 13 years, I suffered a huge number of hits to the head — an estimated 215,000 at least. Nevertheless, I have fared better than many of the players of my era: many suffered from chronic traumatic encephalopathy. (...) For example, some of my fellow Hall of Fame players from that era, Mike Webster, Jim Ringo, John Mackey, and Joe Perry, all suffered from CTE and all are now deceased. I count myself lucky that the main malady affecting me after those many blows to the head is a 60% hearing loss in my left ear — probably due to undiagnosed concussions and particularly to thousands of head slaps by defensive players, whose first hit after the snap was often a right-handed blow to the helmet's open hole over my left ear. (shrink)

_Teachers as Researchers_ urges teachers - as both producers and consumers of knowledge - to engage in the debate about educational research by undertaking meaningful research themselves. Teachers are being encouraged to carry out research in order to improve their effectiveness in the classroom, but this book suggests that they also reflect on and challenge the reductionist and technicist methods that promote a 'top down' system of education. It argues that only by engaging in complex, critical research will teachers rediscover (...) their professional status, empower their practice in the classroom and improve the quality of education for their pupils. Now re-released to introduce this classic guide for teachers, the new edition of _Teachers as Researchers_ now also includes an introductory chapter by Shirley R. Steinberg that sets the book within the context of both the subject and the historical perspective. In addition, she also provides information on some key writing that extends the bibliography of this influential book thereby bringing the material fully up to date with current research. Postgraduate students of education and experienced teachers will find much to inspire and encourage them in this definitive book. (shrink)

"He completed the assignment in two phases: The photographs made during the first phase capture the natural ruggedness of the terrain and establish its relationship to the developed neighboring enclaves. Those made during the second phase not only record the actual construction process but also reveal Deal's personal perspective on the qualities of light and the creation of form. Represented in this book as a selection from the resulting portfolio, Topos, a Greek word meaning place, site, position, and occasion - (...) Deal's artistic legacy to the Gerry Center."--BOOK JACKET. (shrink)

This book makes the case for the news media to take the lead in combatting key threats to American society including racial injustice, economic disparity, and climate change by adopting an "ethics of care" in reporting practices. Examining how traditional news coverage of race, economics and climate change has been dedicated to straightforward facts, the author asserts that journalism should now respond to societal needs by adopting a moral philosophy of the "ethics of care," opening the door to empathetic yet (...) factual and fair coverage of news events, with a goal to move public opinion to the point that politicians are persuaded to take effective action. The book charts a clear path for how this style of ethics can be applied by today's journalists, tracing the emergence of this empathy-based ethics from feminist philosophy in the 1980s. It ultimately urges ethical news organizations to adopt the ethics of care, based on the human emotion prioritized by Scottish Enlightenment philosopher David Hume, and to pursue a more pro-active, solutions-seeking coverage of current events. This is an invaluable text for students and academics in the fields of journalism ethics, media ethics and media law, as well as for media professionals looking for a fresh perspective on practicing ethical journalism. (shrink)

In a recent paper, Kyselo argues that an enactive approach to selfhood can overcome ‘the body-social problem’: “the question for philosophy of cognitive science about how bodily and social aspects figure in the individuation of the human individual self” ). Kyselo’s claim is that we should conceive of the human self as a socially enacted phenomenon that is bodily mediated. Whilst there is much to be praised about this claim, I will demonstrate in this paper that such a conception of (...) self ultimately leads to a strained interpretation of how bodily and social processes are related. To this end, I will begin the paper by elucidating the body-social problem as it appears in modern cognitive science and then expounding Kyselo’s solution, which relies on a novel interpretation of Jonas’s concept of needful freedom. In response to this solution, I will highlight two problems which Kyselo’s account cannot overcome in its current state. I will argue that a more satisfactory solution to the body-social problem involves a re-conception of the human body as irrevocably socially constituted and the human social world as irrevocably bodily constituted. On this view, even the most minimal sense of selfhood cannot privilege either bodily or social processes; instead, the two are ontologically entwined such that humans are biosocial selves. (shrink)

I propose we abandon the unit concept of "the evolutionary synthesis". There was much more to evolutionary studies in the 1920s and 1930s than is suggested in our commonplace narratives of this object in history. Instead, four organising threads capture much of evolutionary studies at this time. First, the nature of species and the process of speciation were dominating, unifying subjects. Second, research into these subjects developed along four main lines, or problem complexes: variation, divergence, isolation, and selection. Some calls (...) for 'synthesis' focused on these problem complexes (sometimes on one of these; other times, all). In these calls, comprehensive and pluralist compendia of plausibly relevant elements were preferred over reaching consensus about the value of particular formulae. Third, increasing confidence in the study of common problems coincided with methodological and epistemic changes associated with experimental taxonomy. Finally, the surge of interest in species problems and speciation in the 1930s is intimately tied to larger trends, especially a shifting balance in the life sciences towards process-based biologies and away from object-based naturalist disciplines. Advocates of synthesis in evolution supported, and were adapting to, these larger trends. (shrink)

In recent philosophy of science there has been much discussion of both pluralism, which embraces scientific terms with multiple meanings, and eliminativism, which rejects such terms. Some recent work focuses on the conditions that legitimize pluralism over eliminativism – the conditions under which such terms are acceptable. Often, this is understood as a matter of encouraging effective communication – the danger of these terms is thought to be equivocation, while the advantage is thought to be the fulfilment of ‘bridging roles’ (...) that facilitate communication between different scientists and specialisms. These theories are geared towards regulating communication between scientists qua scientists. However, this overlooks an important class of harmful equivocation that involves miscommunication between scientists and nonscientists, such as the public or policymakers. To make my case, I use the example of theory of mind, also known as ‘mindreading’ and ‘mentalizing’, and broadly defined as the capacity to attribute mental states to oneself and others. I begin by showing that ‘theory of mind’ has multiple meanings, before showing that this has resulted in harmful equivocations of a sort and in a way not accounted for by previous theories of pluralism and eliminativism. (shrink)

Intellectual and professional reforms in evolutionary studies between 1935 and 1950 included substantial expansion, diversification, and realignment of community infrastructure. Theodosius Dobzhansky, Julian Huxley and Alfred Emerson organized the Society for the Study of Speciation at the 1939 AAAS Columbus meeting as one response to concerns about ‘isolation’ and ‘lack of contact’ among speciation workers worried about ‘dispersed’ and ‘scattered’ resources in this newly robust ‘borderline’ domain. Simply constructed, the SSS sought neither the radical reorganization of specialities nor the creation (...) of some new discipline. Instead, it was designed to facilitate: to simplify exchange of information and to provide a minimally invasive avenue for connecting disparate researchers. Emerson served as SSS secretary and was its principal agent. After publishing one block of publications, however, the SSS became ‘quiescent’. Anxious to promote his own agenda, Ernst Mayr tried to manoeuvre around Emerson in an effort to revitalize the project. After meeting impediments, he moved his efforts elsewhere. The SSS was too short-lived to merit a claim for major impact within the community; however, it reveals important features of community activity during the synthesis period and stands in contrast to later efforts by George Simpson, Dobzhansky, and Mayr. (shrink)

Religion is an important element of end-of-life care on the paediatric intensive care unit with religious belief providing support for many families and for some staff. However, religious claims used by families to challenge cessation of aggressive therapies considered futile and burdensome by a wide range of medical and lay people can cause considerable problems and be very difficult to resolve. While it is vital to support families in such difficult times, we are increasingly concerned that deeply held belief in (...) religion can lead to children being potentially subjected to burdensome care in expectation of ‘miraculous’ intervention. We reviewed cases involving end-of-life decisions over a 3-year period. In 186 of 203 cases in which withdrawal or limitation of invasive therapy was recommended, agreement was achieved. However, in the 17 remaining cases extended discussions with medical teams and local support mechanisms did not lead to resolution. Of these cases, 11 (65%) involved explicit religious claims that intensive care should not be stopped due to expectation of divine intervention and complete cure together with conviction that overly pessimistic medical predictions were wrong. The distribution of the religions included Protestant, Muslim, Jewish and Roman Catholic groups. Five of the 11 cases were resolved after meeting religious community leaders; one child had intensive care withdrawn following a High Court order, and in the remaining five, all Christian, no resolution was possible due to expressed expectations that a ‘miracle’ would happen. (shrink)

Is there any number of people you should save from paralysis rather than saving one person from death? Is there any number of people you should save from a headache rather than saving one person from death? Many people answer ‘yes’ and ‘no’, respectively. They therefore accept a partially aggregative moral view. Patrick Tomlin has recently argued that the most promising partially aggregative views in the literature have implausible implications in certain cases in which there are additions or subtractions to (...) the groups of people that we can save. Several philosophers have begun responding to this argument by developing partially aggregative views that avoid the relevant implications. In this paper, I extend Tomlin’s argument to create a dilemma that no partially aggregative view can avoid. I conclude that we should accept a fully aggregative moral view. (shrink)

My hypothesis is that human personhood has ancient biological roots which make it possible for social reinforcers to contribute to the gradual construction of real persons who are always deeper than the stories about them. Multiple persons do sometimes emerge from one human organism. Rather than try to prove they are real, I explore the consequences of assuming them to be genuine emergentsthat become social environment to one another. I suggest that the multiple-persons phenomenon has profoundly influenced the development of (...) human ethics and the attainment of personhood through the pursuit of ideals. (shrink)

This paper seeks to consider the similarities between Kierkegaard’s life stages and Lacan’s orders to demonstrate that we can understand each description in a structurally similar way to the other. Accordingly, a reading of Kierkegaard is developed that uses his life stages to describe a metapsychology, and a reading of Lacan is developed that shows how his orders can be conceived of progressively. All this leads to a further analysis of the different ways in which each stage relates to repetition (...) and a culmination in which the achievement of faith in Kierkegaard is thought together with the analytic cure in Lacan. (shrink)

Objective or subjective : that is the question -- The science of nature and the nature of science -- Theory : explanation, not speculation -- Is science the whole story? -- Our unique universe -- Nature's laws -- Facing the universe -- The hunt for reality.

Leonardo Polo proposes a new interpretation of the history of philosophy, based on three remarkable periods: Athens, with Aristotle; Paris, With Thomas Aquinas; and Berlin, with Hegel. Taking advantage of the study of these three great thinkers, he has built the main outlines of his own philo-sophy, particularly his transcendental anthropology, amplifying remar-kably the transcendentals of classic philosphy. It also contains a new and very seminal interpretation of man. Finally, it supplies a reorientation of modern philosophy as a whole.