Results for 'Kevin Maciuba'

961 found
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  1.  16
    Co‐translational folding of nascent polypeptides: Multi‐layered mechanisms for the efficient biogenesis of functional proteins.Kevin Maciuba, Nandakumar Rajasekaran, Xiuqi Chen & Christian M. Kaiser - 2021 - Bioessays 43 (7):2100042.
    The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co‐translational folding and distinguish it from refolding in solution. Here, we highlight some of these recent findings from biochemical and biophysical studies and their potential significance for cellular protein biogenesis. In particular, we focus on nascent chain interactions with the (...)
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  2.  42
    Social Trust: Foundational and Philosophical Issues.Kevin Vallier & Michael Weber (eds.) - 2021 - Routledge.
    "With increasingly divergent views and commitments, and an all-or-nothing mindset in political life, it can seem hard to sustain the level of trust in other members of our society necessary to ensure our most basic institutions work. This book features interdisciplinary perspectives on social trust. The contributors address four main topics related to social trust. The first topic is empirical and formal work on norms and institutional trust, especially the relationships between trust and human behaviour. The second topic concerns trust (...)
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  3. A Defense of Lucky Understanding.Kevin Morris - 2012 - British Journal for the Philosophy of Science 63 (2):357-371.
    It is plausible to think that the epistemic benefit of having an explanation is understanding. My focus in this article is on the extent to which explanatory understanding, perhaps unlike knowledge, is compatible with certain forms of luck—the extent to which one can understand why something is the case when one is lucky to truly believe an explanatorily relevant proposition. I argue, contra Stephen Grimm ([2006]) and Duncan Pritchard ([2008], [2009]), that understanding quite generally is compatible with luckily believing a (...)
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  4.  69
    From Caring Entrepreneur to Caring Enterprise: Addressing the Ethical Challenges of Scaling up Social Enterprises.Kevin André & Anne-Claire Pache - 2016 - Journal of Business Ethics 133 (4):659-675.
    This paper advances the conception of social entrepreneurs as caring entrepreneurs. We argue that the care ethics of social entrepreneurs, implying the pursuit of caring goals through caring processes, can be challenged when they engage in the process of scaling up their ventures. We propose that social entrepreneurs can sustain their care ethics as the essential dimension of their venture only if they are able to build a caring enterprise. Organizational care designates the set of organizing principles that facilitate the (...)
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  5.  1
    On the Human Condition in the Zhuangzi.Kevin J. Turner - 2025 - Philosophy East and West 75 (1):189-209.
    This article argues that xing 性 in the Zhuangzi 莊子 should not be understood as “human nature” but as “human condition.” It introduces the problem of interpreting xing as “human nature” by surveying relevant English-language literature before detailing the interpretive paradigm of Chinese accounts, showing how the latter’s appropriation of the language of substance ontology hinders an accurate portrayal of Daoist xing. It argues that xing should be interpreted in connection to the concept of ming 命 understood as contingent, natural, (...)
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  6. Existentialism: An Introduction.Kevin Aho - 2014 - Medford, MA: Polity.
    Provides an accessible and scholarly introduction to the core ideas of the existentialist tradition. Kevin Aho draws on a wide range of existentialist thinkers in chapters centering on the key themes of freedom, being-in-the-world, alienation, nihilism, anxiety and authenticity. He also addresses important but often overlooked issues in the canon of existentialism, with discussions devoted to the role of embodiment, the movement's contribution to ethics, politics, and environmental and comparative philosophies, as well as its influence on contemporary psychiatry and (...)
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  7.  44
    “We’re protecting them to death”—A Heideggerian interpretation of loneliness among older adults in long-term care facilities during COVID-19.Kevin Aho - 2023 - Phenomenology and the Cognitive Sciences 22 (5):1053-1066.
    In this paper, I draw on Heidegger’s phenomenology of “moods” (_Stimmungen_) to interpret loneliness as a diffused and atmospheric feeling-state that often undergirds the lives of older adults, shaping the ways in which they are attuned to and make sense of the world. I focus specifically on residents in long-term care facilities to show how the social isolation and lockdown measures of the COVID-19 pandemic dramatically intensified the mood. The aim is to shed light on how profound and totalizing the (...)
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  8. Sensitivity and Higher-Order Knowledge.Kevin Wallbridge - 2016 - Pacific Philosophical Quarterly.
    Vogel, Sosa, and Huemer have all argued that sensitivity is incompatible with knowing that you do not believe falsely, therefore the sensitivity condition must be false. I show that this objection misses its mark because it fails to take account of the basis of belief. Moreover, if the objection is modified to account for the basis of belief then it collapses into the more familiar objection that sensitivity is incompatible with closure.
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  9.  47
    A critique of the principle of ‘respect for autonomy’, grounded in African thought.Kevin G. Behrens - 2018 - Developing World Bioethics 18 (2):126-134.
    I give an account how the principle of ‘respect for autonomy’ dominates the field of bioethics, and how it came to triumph over its competitors, ‘respect for persons’ and ‘respect for free power of choice’. I argue that ‘respect for autonomy’ is unsatisfactory as a basic principle of bioethics because it is grounded in too individualistic a worldview, citing concerns of African theorists and other communitarians who claim that the principle fails to acknowledge the fundamental importance of understanding persons within (...)
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  10.  22
    Existential Medicine: Essays on Health and Illness.Kevin Aho (ed.) - 2018 - Lanham: Rowman & Littlefield.
    This book offers cutting edge research on the modifications and disruptions of bodily experience in the context of anxiety, depression, trauma, chronic illness, pain, and aging. It presents original contributions in applied phenomenology, biomedical ethics, and the use of medical technologies.
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  11.  67
    Private Equity and the Public Good.Kevin Morrell & Ian Clark - 2010 - Journal of Business Ethics 96 (2):249 - 263.
    The dominance of agency theory can reduce our collective scope to analyse private equity in all its diversity and depth. We contribute to theorisation of private equity by developing a contrasting perspective that draws on a rich tradition of virtue ethics. In doing so, we juxtapose 'private equity' with 'public good' to develop points of rhetorical and analytical contrast. We develop a typology differentiating various forms of private equity, and focus on the 'take private' form. These takeovers are where private (...)
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  12.  34
    COVID-19 vaccine boosters for young adults: a risk benefit assessment and ethical analysis of mandate policies at universities.Kevin Bardosh, Allison Krug, Euzebiusz Jamrozik, Trudo Lemmens, Salmaan Keshavjee, Vinay Prasad, Marty A. Makary, Stefan Baral & Tracy Beth Høeg - 2024 - Journal of Medical Ethics 50 (2):126-138.
    In 2022, students at North American universities with third-dose COVID-19 vaccine mandates risk disenrolment if unvaccinated. To assess the appropriateness of booster mandates in this age group, we combine empirical risk-benefit assessment and ethical analysis. To prevent one COVID-19 hospitalisation over a 6-month period, we estimate that 31 207–42 836 young adults aged 18–29 years must receive a third mRNA vaccine. Booster mandates in young adults are expected to cause a net harm: per COVID-19 hospitalisation prevented, we anticipate at least (...)
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  13. Social Groups Are Concrete Material Particulars.Kevin Richardson - 2022 - Canadian Journal of Philosophy 52 (4):468-483.
    It is natural to think that social groups are concrete material particulars, but this view faces an important objection. Suppose the chess club and nature club have the same members. Intuitively, these are different clubs even though they have a common material basis. Some philosophers take these intuitions to show that the materialist view must be abandoned. I propose an alternative explanation. Social groups are concrete material particulars, but there is a psychological explanation of nonidentity intuitions. Social groups appear coincident (...)
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  14.  54
    Group evolutionary strategies: Dimensions and mechanisms.Kevin MacDonald - 1994 - Behavioral and Brain Sciences 17 (4):629-630.
  15. On the automaticity of emotion.Lisa Feldman Barrett, Kevin N. Ochsner & James J. Gross - 2007 - In John A. Bargh (ed.), Social Psychology and the Unconscious: The Automaticity of Higher Mental Processes. Frontiers of Social Psychology. Psychology Press. pp. 173-217.
  16.  38
    Beyond the Opposition Between Altruism and Self-interest: Reciprocal Giving in Reward-Based Crowdfunding.Kévin André, Sylvain Bureau, Arthur Gautier & Olivier Rubel - 2017 - Journal of Business Ethics 146 (2):313-332.
    Increasingly, frontiers between business and philanthropy seem to be blurred. Reward-Based Crowdfunding platforms contribute to this blurring of lines since they propose funders to support both for-profit and philanthropic projects. Our empirical paper explores the case of Ulule, the leading crowdfunding platform in Europe. Our results, based on a statistical analysis of more than 3000 projects, show that crowdfunding platforms foster specific kinds of relationships relying on reciprocal giving, beyond the usual opposition between altruistic and selfish motivations. We use the (...)
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  17.  24
    Is There Any Virtue in Offsetting?Kevin Meeker - 2022 - Ethics, Policy and Environment 25 (3):258-260.
    Do we have a strong reason to offset even if offsetting is morally inefficient? Some philosophers – such as John Broome – argue that justice-based climate duties require us to contribute money to o...
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  18.  12
    The Unified Brain Based Determination of Death and DCCD/NRP: Curb Your Enthusiasm.G. Kevin Donovan & Christopher DeCock - 2024 - American Journal of Bioethics 24 (6):87-88.
    In his article, a unified brain-based determination of death is described by James Bernat (2024) as a permanent cessation of systemic circulation causing a permanent cessation of brain circulation...
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  19. The peculiar case of Lehrer’s lawyer.Kevin Wallbridge - 2018 - Synthese 195 (4):1615-1630.
    The peculiar case of Lehrer’s lawyer purports to describe a scenario in which a subject has a justified belief, indeed knowledge, despite the fact that their belief is not causally or counterfactually sustained by any good reasons for it. The case has proven controversial. While some agree with Lehrer’s assessment of the case, others disagree, leading to a schism among accounts of the basing relation. In this paper I aim to reconcile these camps and put simple causal and counterfactual accounts (...)
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  20.  8
    Giorgio Agamben: Beyond the Threshold of Deconstruction.Kevin Attell - 2015 - New York: Fordham University Press.
    Traces Italian philosopher Giorgio Agamben's engagement with deconstructive thought from his early work in the 1960s to the present, examining his key concepts - infancy, Voice, potentiality, sovereignty, bare life, messianism - in relation to key texts and concepts in Jacques Derrida's work.
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  21.  19
    Why Higher Working Memory Capacity May Help You Learn: Sampling, Search, and Degrees of Approximation.Kevin Lloyd, Adam Sanborn, David Leslie & Stephan Lewandowsky - 2019 - Cognitive Science 43 (12):e12805.
    Algorithms for approximate Bayesian inference, such as those based on sampling (i.e., Monte Carlo methods), provide a natural source of models of how people may deal with uncertainty with limited cognitive resources. Here, we consider the idea that individual differences in working memory capacity (WMC) may be usefully modeled in terms of the number of samples, or “particles,” available to perform inference. To test this idea, we focus on two recent experiments that report positive associations between WMC and two distinct (...)
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  22. Causal Closure, Causal Exclusion, and Supervenience Physicalism.Kevin Morris - 2014 - Pacific Philosophical Quarterly 95 (1):72-86.
    This article considers the recent defense of the supervenience approach to physicalism due to Jaegwon Kim. Kim argues that supervenience supports physical causal closure, and that causal closure supports physicalism – indeed, a kind of reductive physicalism – and thus that supervenience suffices for physicalism. After laying out Kim's argument, I ask whether its success would truly vindicate the role of supervenience in defining physicalist positions. I argue that it would not, and that insofar as Kim's defense of supervenience physicalism (...)
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  23.  50
    Inference to the best explanation and Norton's material theory of induction.Kevin Davey - 2021 - Studies in History and Philosophy of Science Part A 85:137-144.
  24.  78
    The missing dialogue between Heidegger and Merleau-ponty: On the importance of the zollikon seminars.Kevin A. Aho - 2005 - Body and Society 11 (2):1-23.
    Heidegger’s failure to discuss ‘the body’ in Being and Time has generated a cottage industry of criticism. In his recently translated Zollikon Seminars, Heidegger provides a response to the critics by offering a thematic account of the body that is strikingly similar to Merleau-Ponty’s account in Phenomenology of Perception. In this article, I draw on the parallels between these two texts in order to see how Heidegger’s neglect of the body affects his early project of fundamental ontology and to determine (...)
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  25.  9
    Kultur und Bildung: die Geisteswissenschaften und der Zeitgeist des Naturalismus.Ralf Glitza & Kevin Liggieri (eds.) - 2019 - Freiburg: Verlag Karl Alber.
    Gegenstand des Bandes ist eine Profilierung der Kulturphilosophie mit dem Ziel ihrer notigen Selbstbehauptung gegenuber einem gegenwartigen Naturalismus. Ein zentrales Ratsel der Gegenwartsphilosophie ist das Verhaltnis unseres Bewusstseins, der Perspektive der ersten Person machtig und Urheber der Kultur zu sein, zu den Erkenntnissen der Kognitions- sowie der Evolutionswissenschaften seit Darwin. In diesen scheint von der Natur her auf die Kultur ein neues Licht zu fallen. Dies ist ebenso faszinierend wie interessant. Es ist aber auch eine Herausforderung: Der Begriff der "Welt" (...)
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  26.  32
    Contexts of Suffering: A Heideggerian Approach to Psychopathology.Kevin Aho - 2019 - Rowman & Littlefield International.
    This book explores new phenomenological research on the structural disruptions of spatiality, temporality, and understanding in the context of anxiety and depressive disorders. It offers critiques of mainstream psychopathology, taking a transdisciplinary approach to the relationship between mental illness and self-constitution.
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  27.  36
    Serendipity and Social Justice: How Someone with a Physical Disability Succeeds in Clinical Bioethics.Kevin T. Mintz - forthcoming - Narrative Inquiry in Bioethics.
    Trainees with disabilities in health-related professions are often subjected to structural ableism in medicine: the discriminatory manifestation of lowered expectations towards people with disabilities by medical professionals. In this case study, I reflect on my experiences as the first individual with significant disabilities to be offered a postdoctoral fellowship in clinical bioethics at the National Institutes of Health. I focus on the following question: What arrangements need to be in place in order for someone with my level of disability to (...)
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  28.  49
    Foucault's Aestheticism.Kevin Lamb - 2005 - Diacritics 35 (2):43-64.
    "Foucault's Aestheticism" asks to what extent critique as Foucault conceives it can be read as a form of style. Starting from Foucault's description of "aestheticism" as "self-transformation," Lamb argues that accounts of Foucauldian critique have often sought to establish Foucault's position as one of affirmation or opposition without carefully setting out the terms by which his practice and relation to the self shift with respect to the institutions, disciplines, and practices that form his objects of study. By focusing on Foucault's (...)
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  29.  28
    Partiality and distributive justice in African bioethics.Kevin Gary Behrens - 2017 - Theoretical Medicine and Bioethics 38 (2):127-144.
    African ethical theories tend to hold that moral agents ought to be partial, in the sense that they should favour members of their family or close community. This is considered an advantage over the impartiality of many Western moral theories, which are regarded as having counterintuitive implications, such as the idea that it is unethical to save a family member before a stranger. The partiality of African ethics is thought to be particularly valuable in the context of bioethics. Thaddeus Metz, (...)
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  30. Position open.Helen Keller, Kevin Host, Lisa Benner, Carrie Smith, David Bird, Laura Groshong, Eric Huffman, Karen Hansen, Mary Ashworth & Shirley Bonney - 2006 - In Laurie Dimauro (ed.), Ethics. Greenhaven Press. pp. 329-4763.
  31.  58
    The importance of a human viewpoint on computer natural language capabilities: a Turing test perspective.Kevin Warwick & Huma Shah - 2016 - AI and Society 31 (2):207-221.
  32.  92
    Ethics and Business: An Introduction.Kevin Gibson - 2007 - New York: Cambridge University Press.
    In this lively undergraduate textbook, Kevin Gibson explores the relationship between ethics and the world of business, and how we can serve the interests of both. He builds a philosophical groundwork that can be applied to a wide range of issues in ethics and business, and shows readers how to assess dilemmas critically and work to resolve them on a principled basis. Using case studies drawn from around the world, he examines topics including stakeholder responsibilities, sustainability, corporate social responsibility, (...)
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  33.  29
    Assisted suicide: the liberal, humanist case against legalization.Kevin L. Yuill - 2013 - Houndmills, Basingstoke, Hampshire ;: Palgrave-Macmillan.
    Kevin Yuill goes straight to the heart of a difficult issue. Critical of both sides of the discussion, this book presents an up-to-date analysis of the direction discussion is taking, showing that atheists, libertarians, those favouring abortion rights and stem-cell research should stand beside their religious compatriots in opposing legalization of assisted suicide. The author shows that the real issue behind the debate is not euthanasia but suicide. Rather than focusing on tragic cases, he indicates the real damage that (...)
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  34. Aparté: Conceptions and Deaths of Søren Kierkegaard.Sylviane Agacinski, Kevin Newmark, John Vignaux Smyth & John D. Caputo - 1991 - International Journal for Philosophy of Religion 29 (2):113-122.
     
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  35.  23
    Law, learning and representation.Kevin D. Ashley & Edwina L. Rissland - 2003 - Artificial Intelligence 150 (1-2):17-58.
  36.  51
    Is there more than one Generation of Matter in the Enneads?Kevin Corrigan - 1986 - Phronesis 31 (1):167-181.
  37.  16
    Tisser une trame relationnelle autour de l’enfant : les affiliations familiales en contexte de gestation pour autrui et de don d’ovules.Kévin Lavoie & Isabel Côté - 2023 - Dialogue: Families & Couples 239 (1):67-83.
    Le présent article porte sur la trame relationnelle tissée autour de l’enfant né par gestation pour autrui ou conçu grâce à un don d’ovules, et plus spécifiquement sur les affiliations familiales qui émergent de ce processus inédit d’enfantement à plusieurs. La démonstration s’appuie sur les récits de 38 femmes canadiennes impliquées dans une entente de procréation assistée avec autrui en tant que mères, femmes porteuses ou donneuses. Deux cas de figure mettant en lumière la construction des liens d’apparentement entre les (...)
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  38.  23
    Correction to: Heisenbergian explanation and Husserlian evidence: ontological significance in idealized language.Kevin Mager - 2022 - Continental Philosophy Review 55 (3):407-407.
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  39.  25
    Aquinas and Hare on Fanaticism.Kevin McDonnell - 1974 - Proceedings of the American Catholic Philosophical Association 48:218-227.
  40.  15
    The Status Quaestionis of Ecumenism.Kevin McDonald - forthcoming - New Blackfriars.
    In 2016 Pope Francis went to Lund in Sweden for a joint service with the Lutherans to begin the events marking the 500th anniversary of the Reformation. Catholics have also been involved in conferences and other events that have been organized as part of this anniversary. The context and background to the Catholic Church's involvement is the Church's commitment to ecumenical dialogue made at the Second Vatican Council. The theological basis for that commitment is to be found in the Second (...)
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  41.  24
    Case Studies: Two Cardiac Arrests, One Medical Team.Kevin M. McIntyre, Robert C. Benfari & M. Pabst Battin - 1982 - Hastings Center Report 12 (2):24.
  42.  18
    Teaching analysis.Kevin McKeown & Felicity Green - 1993 - Health Care Analysis 1 (2):203-205.
  43.  17
    A systematic review of peer review for scientific manuscripts.Bradley P. Larson & Kevin C. Chung - 2012 - In Zdravko Radman (ed.), The Hand. MIT Press. pp. 7--1.
  44. A fan effect in anaphor processing: effects of multiple distractors.Kevin S. Autry & William H. Levine - 2014 - Frontiers in Psychology 5.
  45. Technology, Liberty, and Guardrails.Kevin Mills - 2024 - AI and Ethics (unknown):1-8.
    Technology companies are increasingly being asked to take responsibility for the technologies they create. Many of them are rising to the challenge. One way they do this is by implementing “guardrails”: restrictions on functionality that prevent people from misusing their technologies (per some standard of misuse). While there can be excellent reasons for implementing guardrails (and doing so is sometimes morally obligatory), I argue that the unrestricted authority to implement guardrails is incompatible with proper respect for user freedom, and is (...)
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  46.  18
    Counter-Experiences: Reading Jean-Luc Marion.Kevin Hart (ed.) - 2007 - University of Notre Dame Press.
    Unarguably, Jean-Luc Marion is the leading figure in French phenomenology as well as one of the proponents of the so-called “theological turn” in European philosophy. In this volume, Kevin Hart has assembled a stellar group of philosophers and theologians from the United States, Britain, France, and Australia to examine Marion's work—especially his later work—from a variety of perspectives. The resulting volume is an indispensable resource for scholars working at the intersection of philosophy and theology. “This is a ground-breaking book (...)
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  47.  24
    The blind obedience of others: a better than average effect in a Milgram-like experiment.Laurent Bègue & Kevin Vezirian - 2024 - Ethics and Behavior 34 (4):235-245.
    In two highly powered studies (total N = 1617), we showed that individuals estimated that they would stop earlier than others in a Milgram-like biomedical task leading to the death of an animal, confirming the relevance of the Better than Average Effect (BTAE) in a new research setting. However, this effect was not magnified among participants displaying high self-esteem. We also showed that participants who already knew obedience studies expected that others would be more obedient and would administer more damaging (...)
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  48. An AI model of case-based legal argument from a jurisprudential viewpoint.Kevin D. Ashley - 2002 - Artificial Intelligence and Law 10 (1-3):163-218.
    This article describes recent jurisprudential accountsof analogical legal reasoning andcompares them in detail to the computational modelof case-based legal argument inCATO. The jurisprudential models provide a theoryof relevance based on low-levellegal principles generated in a process ofcase-comparing reflective adjustment. Thejurisprudential critique focuses on the problemsof assigning weights to competingprinciples and dealing with erroneously decidedprecedents. CATO, a computerizedinstructional environment, employs ArtificialIntelligence techniques to teach lawstudents how to make basic legal argumentswith cases. The computational modelhelps students test legal hypotheses againsta database of (...)
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  49. Acceleration and Time Pathologies: The Critique of Psychology in Heidegger's Beiträge.Kevin Aho - 2007 - Time and Society 16 (1):25-42.
    In his Contributions to Philosophy, Martin Heidegger introduces "acceleration" as one of the three symptoms--along with "calculation" and the "outbreak of massiveness"--of our technological way of "being-in-the-world." In this article, I unpack the relationship between these symptoms and draw a twofold conclusion. First, interpreting acceleration in terms of time pathologies, I suggest the self is becoming increasingly fragmented and emotionally overwhelmed from chronic sensory arousal and time pressure. This experience makes it difficult for us to qualitatively distinguish what matters to (...)
     
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  50. Theologians of spiritual transformation: A proposal for reading René Girard through the lenses of Hans Urs Von balthasar and John Cassian.Kevin Mongrain - 2012 - Modern Theology 28 (1):81-111.
    This essay contends that René Girard is not a philosopher or a scientist whose ideas are open to theological appropriation. Instead, contrary to his assertions otherwise, the Girard corpus ought to be read as if it were articulating a form of theology whose primary intellectual home can ultimately be found on a theological map. As the field of Girardian theology grows, it becomes more evident that we need some theological lenses for examining the theology already lying waiting—sometimes inchoately, sometimes not—in (...)
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