The philosophical inheritance of Mykola Shlemkevich remains small worked out for today. In part because his works have been scattered, published in various publications under pseudonyms, in part, because of the fact that he has long been is attached the label "nationalist" and sometimes "nationalist fascist. Mykola`s Shlemkevich works fold the philosophical system and it is an obvious fact. They are incorporated by structural and methodological community. It is important to consider the Shlemkevych`s philosophical system it in its fullness and (...) integrity, as in his writings thinker pointed not only to the problems faced by Ukrainian, but also on ways to overcome them. Mykola Shlemkevich always marked practical character of philosophy, he considered that philosophy must be added to practice. He also mentioned this in his work "The essence of philosophy", for which in 1926 got in the Viennese university rank of Ph.D. Slemkevich defines philosophy as the inner essence symbolic systems of science, religion, art, culture. He calls philosophy "the queen of sciences." "Lost Ukrainian man" published in New York in 1954 is a perfect example of deep understanding of the social, political, cultural and philosophical problems faced man of modern times. Thinker notes that everyone naturally seeks happiness, but Ukrainians believe that happiness is oblivion. Shlemkevich emphasizes that it is not true.He notes that there is no oblivion for Ukrainians. He sees solution in leadingout of all complexes on a surface. Solving these problems is the responsibility of the elite, because that philosophers, politicians and artists should be support for people. Also a philosopher investigates the question of the political system that would answer the necessities of Ukrainians most. In his "Ukrainian synthesis or Ukrainian civil war" published in 1946 philosopher considers the title of "creative forces". They are: Ukrainian autocracy - the monarchy, Ukrainian democracy - democracy and the Ukrainian leadership. Contrary to the creative forces are the forces of anarchy. Creative forces can not overcome force of anarchy because operate separately. Also creative forces argue among themselves. One`s of creative forces victory is undesirable because will result in totalitarianism, and it unusual to Ukrainians. Thus a thinker talks about a necessity to find a consensus, because only together they will be able to bringUkraineover to prosperity. (shrink)

The article emphasizes the cultural and educational importance of H. Skovoroda Institute of Philosophy for the spiritual development of the Ukrainian society, especially in the direction of democracy and establishment of the worldview culture as a requirement for the culture of freedom. From the position of the included observer the author of the article describes some episodes of relationship in the scientist’s communities which can be defined as justice and solidary community. On the basis of the Heidegerian scheme, some dangers (...) are analyzed as demands addressed to philosophical thinking. This scheme is used by structuring of the article. The metaphoric of these dangers indicates the contextual problems which are important for producing of philosophical ideas. The experience of the Institute of Philosophy gained by solving of problems is very remarkable for the fulfillment of philosophical studies and educational practices especially by mentoring of the postgraduate students. The fact of naming the Institute after H. Skovoroda is regarded as a symbolic act with a great creative potential and energy which can be used for reviving of national traditions of philosophical thinking. The role of lyric in activating of philosophical ideas is showed. The symbiotic coexisting of the poetry, art, journalism and philosophy is one of the original features of the Skovorodian tradition caring by the well-known representatives of the Institute. All these characteristics joined with the civic culture, which was demonstrated by all generations of the Institute, allow defining it as a metaphysical place with the ability both to follow on the road of the way of light and to represent it on the landscapes of philosophical science and education. The history of the Institute, especially, in the period of its post-totalitarian transformations, gives the opportunity of taking comparison with the Institute for Social Research Frankfurt. The civic courage of the Ukrainian intellectual elites was always initiated, supported and generated by philosophers gathering in Institute of Philosophy. (shrink)

The article proposes the consideration of Skovoroda’s philosophical heritage in the complex contexts of the European philosophical thought in its historical dimension. This complexity was caused through the secular tendency of the Enlightenment ideology with its explanation patterns for human being and social life. The mediological method developed of R. Debray and A. Koschorke is used for analyzing of Skovoroda’s attitudes towards the Enlightenment innovations in cultural and political life. The contemporary narratives of the First, the Second and the Third (...) Enlightenment are applied as pattern for explanation of Skovoroda’s attitude towards the secular trends in the culture and education caused of the Enlightenment ideology. Skovoroda is balancing on the edge of the First and Second Enlightenment: as a philosopher of freedom he makes human responsible for his way of life, but as philosopher of morality he defended the idea of God using the neo-platonic approach. The resurrection of Epicureanism in the Age of Enlightenment was a theoretical challenge for Skovoroda with resonance reactions because his ethical views were based on Epicurus concept of necessity as regulative principle for successful life which can be got without any effort. The religious anthropology developed of Skovoroda is considering in its anthropological-technical aspect. The central ideas of the First Enlightenment — omnipotence of education, disenchanting of religion and project of a new human are rethinking by Skovoroda from the perspective of his religious anthropology with imperatives of self-knowing and making distinction between visual and invisible thereby the way to the eternal truth is possible only possible by the new hermeneutic of the Bible. The semantics and heuristic metaphors in Skovoroda’s works are analyzed, which have a resonance effect with Protestantism and Freema sons ideas, some of which are actualized today. (shrink)

Recombinant adeno‐associated viruses (rAAVs) are promising vectors for the delivery of various genetic constructs into eukaryotic cells. rAAVs have a number of properties that make it possible to successfully use them both in vitro and in vivo. Purification and concentration of rAAV vectors are critical for achieving high viral titer, stability, efficiency, and purity. This review systematically analyses all available purification approaches. The purification methods described in this work differ substantially from each other in mechanisms, efficiency, labor time, and cost. (...) Researchers have to choose a purification algorithm depending on the purpose of their work. We strive to simplify the choice of the necessary and sufficient technique based on the experimental needs and available resources of the laboratory. (shrink)

The author analyzes the evolution of the concept of sovereignty from feudal times through early modernity to the present day. She examines the problematic relationship between the ideas of sovereignty, democracy, and pluralism, and discusses the decline and possible disappearance of sovereignty in the context of globalization.

The article deals with the examination of performance as a social event and a communicative process from the position of the constitutional meta-model of communication. Performance is viewed as a form of communication based on the horizontal relation of its participants because of the informational and symbolical exchange between the performers and audience and its transformative potential. Much attention is paid to the analysis of the transformative power of performance through the lens of notion of liminality. The author draws a (...) conclusion about the communicative nature of performance and fruitfulness of application of the research results to the analysis of performance communicative dimensions. Key words: performance, communication, transmission, ritual, participation, transformation, liminality, communitas. (shrink)

The paper presents the author's approach to ensuring the sustainability of housing and public utilities. The main methods for securing financial stability of the HPU operation are indicated and analyzed. It is established that the key problems affecting the sustainability of the HPU system relate to the operational element i.e. individual enterprises of the industry. The author demonstrates that improvement of the HPU management system is the most expedient method for enhancement of the HPU sustainability. The analysis also focuses on (...) effectivization of sustainability management of heat supply companies. An integrated model for management of a heat supply company is developed, which is decomposed into 3 submodels: 1) an unpaid demand management model ; 2) a lost demand management model ; 3) an integrated management model for a heat supply company, which is based on modelling results of submodels 1-2. To describe the set of the models, the author applies the simulation modeling technique in the environment of the PowerSіm Application Program Package. A scenario analysis is used to assess the efficiency of various management levers for a heat supply company, some conclusions drawn as to the effectiveness of applying such a scenario as improvement of service, which allows achieving a short-term and long-term growth of the liquid financial result as well as a long-term growth of its financial performance. (shrink)

A slight stabilization of some macroeconomic indicators Ukraine in conditions of long-term preservation of structural imbalances in the domestic economy against the background of global economic recovery, reduce consumer demand in the global markets combined with the devaluation of the hryvnia no reason to conclude that ensure the sustainability of enterprises to the likely financial and economic turmoil. Given this situation, the article identifies the main problems of accounting of foreign exchange transactions in Ukraine through the prism of foreign software (...) security. At present actualized issue integration into the European economic space, which leads to aggravation of the issue of financial payments in foreign currency and their reflection in the accounting business. Stand unstable economic situation in the domestic market of Ukraine leads the majority of domestic enterprises to shift to foreign markets. Foreign trade enterprises directly related to the riskiness and exposure to foreign shocks her, so constantly need to monitor the status of foreign security. Based on empirical research using the software package MS Excel, articles in the research and forecasting of external economic security of Ukraine and brought a further increase of this indicator in a strategic perspective. However, foreign financial and payment transactions engaged in enterprise involving consideration of exchange rate fluctuations, in which there are exchange differences significantly affect the financial results of the company. In order to improve the accounting currency transactions in the context of foreign trade enterprises proposed harmonization of national and international accounting systems using international standards in national accounting system and financial reporting. (shrink)

The issue of words combinations draws attention of linguists starting from the second half of the XX c. until the present day. This study is focused on the research of semantic mechanisms of unusually combined lexemes and unexpected collocations in English postmodern short-short stories. Reconsideration of the literary past and ironic view on traditional poetic canons are reflected in postmodern literary texts due to the principles of postmodern poetics. Being distinctive feature of postmodern literature in general, uncertainty creates multiplicity of (...) meanings of entire literary text, as well as separate unexpected collocations, by means of unusually combined lexemes. The aim of the study is to elaborate the phenomenon of valence violation, created by unusually combined lexemes and unexpected collocations in English postmodern short-short stories. To achieve this goal, it is necessary to define the notion of valence and lexeme compatibility, to identify types of valence violation in lexemes combinations, and to provide their possible interpretation. Functioning in English postmodern short-short stories such language units widen boundaries of their usage and their combinatorial profile. Unusually combined lexemes focus the reader’s attention and provoke a cognitive mechanism of continuous searching for a hidden meaning of unexpected collocations and the general message of a literary text. In this research unusually combined lexemes are regarded as special markers of postmodern short-short story genre for which violation of text structure, violation of usual relations between lexemes in logic, semantic and syntactic aspects are quite common. (shrink)

Cellular 3D structures, for example, organoids, are an excellent model for studying and developing treatments for various diseases, including hereditary ones. Therefore, they are increasingly being used in biomedical research. From the point of view of safety and efficacy, recombinant adeno‐associated viral (rAAV) vectors are currently most in demand for the delivery of various transgenes for gene replacement therapy or other applications. The delivery of transgenes using rAAV vectors to various types of organoids is an urgent task, however, it is (...) associated with a number of problems that are discussed in this review. Cellular heterogeneity and specifics of cultivation of 3D structures determine the complexity of rAAV delivery and are sometimes associated with low transduction efficiency. This review surveys the main ways to solve emerging problems and increase the efficiency of transgene delivery using rAAVs to organoids. A clear understanding of the stage of development of the organoid, its cellular composition and the presence of surface receptors will allow obtaining high levels of organoid transduction with existing rAAV vectors. (shrink)

In the article there are examined the main reasons for the use of autstaffing with the purpose to reduce the risk of the staffs activity; there is offered our own order of autstaffing; there is developed a scheme of the complex services autstaffing providing; there is formed a triangle of possibilities for the application of the autstaffing to reduce or to avoid the risk of the staffs activity.

У статті проаналізовано погляди Джона Дьюї на релігієзнавчу частину його філософських знань; виокремлені вчення про релігію та ставлення до Бога в біографічному контексті Джона Дьюї; розглянуто поняття досвіду, віри в релігійному розумінні вченого, а також визначено еволюцію його поглядів на релігійні знання. Систематизовано періоди зацікавлення вченого питаннями релігії. Показано, що найбільший вплив на погляди Джона Дьюї щодо релігії та Бога справили роботи німецьких класиків, дарвінізм та соціальне життя вченого.

У статті запропонований підхід до розробки комплексної системи контролю якості надання дорожньо-будівельних послуг, який базується на моделі формування взаємозв'язку конструктивних, технологічних та організаційних параметрів дорожніх робіт. Модель дозволяє проаналізувати контрольні параметри на стадії виробництва й оцінити їх вплив на якість та надійність об'єкта дорожнього будівництва на відповідній стадії експлуатації, що дає можливість комплексного контролю якості проведення окремих видів дорожніх робіт; якості матеріалів, що використовуються в дорожньому будівництві; підготовки та прийняття конструктивно-технологічних та організаційних рішень під час проведення дорожньо-будівельних робіт.

The article substantiates the necessity of psychoanalytical and existential methodology in interpreting Lesia Ukrainka’s drama Kaminnyi hospodar, including the works of José Ortega y Gasset and Miguel de Unamuno on Don Quixote, Albert Camus on absurd characters, and Jacques Lacan’s The Mirror Stage. Biographical data testify to the critical attitude of the writer to world treatments of the legend. Her challenge to tradition was bold and conscious. It is regarded that the main point of Lesia Ukrainka’s polemics with tradition concerns (...) Don Juan apologetics, introduced by romantics and developed by modernists. Exploring Don Juan’s psychological makeup provides the opportunity to show that all participants of the legend have become victims of Don Juan apologetics. The Don Juan myth has played an integral role in the image of the Person being accepted by characters as a trustful image of the Self. Interpretation of the Mirror Image in The Stone Host and its crucial role in the final scene allows for justifying that the mirror serves the narcissistic characters’ admiration of themselves and shows them not only an attractive appearance but an ideal version of the Self, created by myth. (shrink)

The article presents the results of the authors’ research on the cosmological views of Johannes Keppler in his Latin treatise Harmonices Mundi. The authors discuss the background of composing the treatise concerning the philosophical, religious, and cultural contexts of that period, and give a brief overview of the structure of the treatise, Kepler’s theory and his third law of harmony. The paper demonstrates the connection and reception of philosophical ideas on the harmony of the world in Kepler’s treatise and ancient (...) philosophers, such as Pythagoras, Plato, and Proclus. This shows that Kepler’s philosophical and scientific views largely depended on his theological background. The authors discuss the perception of ancient cosmological ideas in Kepler’s Harmonices Mundi relating to Pythagorean tetractys, five Platonic solids or regular polyhedral, and cosmic harmony as well as Proclus’ theoretical mathematics. (shrink)

The article is devoted to philosophical and hermeneutic analysis of videogame player identity. The purpose of the study is to reveal the general features of the videogame player identity, to distinguish it from gamer identity and to define common levels of its formation, on the basis of which the further methodology of videogame philosophy may be formed without stereotypical views. To achieve it, the classification and systematization, as well as the analysis and synthesis, applied to the identity concept in general (...) and studies on gamer self-identity in particular, have been used. Considering player identity in hermeneutic terms, the authors have delineated the main levels of the player identity formation, namely: videogame preferences, manner of playing and character / personal profile identity. All this levels not only form player identity as an individual way to identify oneself, but also act as a ground for further creation of gamer identity. (shrink)

Kinetic demixing in quaternary mixed oxides has not been investigated previously, either theoretically or experimentally. In this theoretical study, we derive simple and exact analytical expressions that describe the steady-state cation concentration profiles resulting from kinetic demixing in mixed oxides of the O type. The concentration profiles are expressed in terms of cation-vacancy exchange frequency ratios. We assume a random distribution of cations and make use of the Moleko-Allnatt exact sum-rule expression relating the phenomenological coefficients in the ternary random alloy (...) to the vacancy mechanism operative. We employ Monte Carlo simulation of kinetic demixing to verify the result of the analysis. We discuss how kinetic demixing profiles can be processed to obtain atom-vacancy exchange frequency ratios. We also discuss how atom-vacancy exchange frequencies themselves might be obtained from available diffusivities in the quaternary oxide. (shrink)