Qu'est-ce que l'humain? ou comment deux savants assez philosophes et un philosophe assez savant reviennent sur la distinction classique entre nature et culture. Notre tradition culturelle posait une barrière quasiment étanche entre l'animal et l'humain. Nous savons aujourd'hui que nous partageons avec nos cousins les plus récents l'immense majorité de notre matériel génétique. Alors qu'est-ce qui spécifie l'humain? Trois réponses venues de trois disciplines : la neurobiologie, en un va et vient entre sciences cognitives et biologie du système nerveux, la (...) paléoanthropologie, à la charnière de la théorie de l'évolution et de la préhistoire, et la philosophie. (shrink)

The idea of a common currency underlying our choice behaviour has played an important role in sciences of behaviour, from neurobiology to psychology and economics. However, while it has been mainly investigated in terms of values, with a common scale on which goods would be evaluated and compared, the question of a common scale for subjective probabilities and confidence in particular has received only little empirical investigation so far. The present study extends previous work addressing this question, by showing that (...) confidence can be compared across visual and auditory decisions, with the same precision as for the comparison of two trials within the same task. We discuss the possibility that confidence could serve as a common currency when describing our choices to ourselves and to others. others. (shrink)

The first aim of simulation in virtual environment is to help biologists to have a better understanding of the simulated system. The cost of such simulation is significantly reduced compared to that of in vivo simulation. However, the inherent complexity of biological system makes it hard to simulate these systems on non-parallel architectures: models might be made of sub-models and take several scales into account; the number of simulated entities may be quite large. Today, graphics cards are used for general (...) purpose computing which has been made easier thanks to frameworks like CUDA or OpenCL. Parallelization of models may however not be easy: parallel computer programing skills are often required; several hardware architectures may be used to execute models. In this paper, we present the software architecture we built in order to implement various models able to simulate multi-cellular system. This architecture is modular and it implements data structures adapted for graphics processing units architectures. It allows efficient simulation of biological mechanisms. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

Au sein du service de placement où exerce en tant que psychologue le premier auteur de cet article a été développée une recherche longitudinale qui vise à explorer le fonctionnement psychique des adolescents auteurs de violences sexuelles et les modalités de leur accompagnement éducatif et thérapeutique. L’article propose de se centrer sur leur placement en famille d’accueil, la dynamique relationnelle témoignant des particularités des liens tissés avec les premiers objets. La présentation de la situation de Nicolas mettra en exergue les (...) difficultés, malentendus et usures qui semblent illustrer un scénario qui se répète et qui conduit à la rupture. Les auteurs ouvrent une réflexion, dans une perspective psychodynamique, pour tenter de comprendre les mouvements psychiques à l’œuvre du côté de l’adolescent, notamment sur un plan intersubjectif, dans la perspective développée par René Kaës, et invitent à s’intéresser aux adaptations nécessaires au sein des dispositifs éducativo-thérapeutiques d’accompagnement. (shrink)

Although complex hallucinations are extremely vivid, painful symptoms in schizophrenia, little is known about the underlying mechanisms of multisensory integration in such a phenomenon. We investigated the neural basis of these altered states of consciousness in a patient with schizophrenia, by combining state of the art neuroscientific exploratory methods like functional MRI, diffusion tensor imaging, cortical thickness analysis, electrical source reconstruction and trans-cranial magnetic stimulation. The results shed light on the functional architecture of the hallucinatory processes, in which unimodal information (...) from different modalities is strongly functionally connected to higher-order integrative areas. (shrink)

As part of the conference commemorating Theoria's 75th anniversary, a round table discussion on philosophy publishing was held in Bergendal, Sollentuna, Sweden, on 1 October 2010. Bengt Hansson was the chair, and the other participants were eight editors-in-chief of philosophy journals: Hans van Ditmarsch (Journal of Philosophical Logic), Pascal Engel (Dialectica), Sven Ove Hansson (Theoria), Vincent Hendricks (Synthese), Søren Holm (Journal of Medical Ethics), Pauline Jacobson (Linguistics and Philosophy), Anthonie Meijers (Philosophical Explorations), Henry S. Richardson (Ethics) and Hans Rott (...) (Erkenntnis). (shrink)

As part of the conference commemorating Theoria's 75th anniversary, a round table discussion on philosophy publishing was held in Bergendal, Sollentuna, Sweden, on 1 October 2010. Bengt Hansson was the chair, and the other participants were eight editors‐in‐chief of philosophy journals: Hans van Ditmarsch (Journal of Philosophical Logic), Pascal Engel (Dialectica), Sven Ove Hansson (Theoria), Vincent Hendricks (Synthese), Søren Holm (Journal of Medical Ethics), Pauline Jacobson (Linguistics and Philosophy), Anthonie Meijers (Philosophical Explorations), Henry S. Richardson (Ethics) and Hans Rott (...) (Erkenntnis). (shrink)

I analyze the complex relations between Pascal and the three figures of Montaigne, Descartes, and St. Augustine, and the relations the first two figures bear to St. Augustine. For Pascal's philosophy, one is in effect a resource , another a way of thinking that he makes his own , and yet another serves as a model . I further investigate Pascal's anti-Augustinism, that is, some of the points of resistance in Pascal against the thought of St. Augustine. Central to this (...) investigation is the famous rapprochement between the cogitos of Augustine and Descartes, which requires a consideration of what, for Pascal, it means "to say the same thing." This analysis leads us to two conclusions: first, Augustine's The City of God should be placed among the number of works that Pascal did not read; second, there are fundamental philosophical reasons for Pascal to reject certain theses central to that work. Above all, there should no longer be any need to assume a merely abstract conception of an unproblematic Augustinianism in Pascal. (shrink)

Pascal a revendique l'abandon de l'etude des sciences au profit de celle de l'homme. Qu'entendre par l'etude de l'homme? D'abord la recherche de la nature du moi humain. La fecondite que L'art de persuader accorde au je pense donc je suis, en tant que principe d'une physique entiere, est telle qu'en est deniee toute portee au cogito augustinien. Mais si Pascal prend acte de l'innovation radicale des Meditationes en creant en francais le moi, c'est pour dessaisir ce moi de sa (...) primaute metaphysique et ne le trouver que dans la depravation de la volonte. Le moi donc, mais pas encore l'homme. Ensuite, apres l'echec des Provinciales, le dessein apologetique pascalien consiste a montrer la superiorite de la vraie religion sur les philosophies, qui seule peut rendre raison de la double condition de l'homme. Ce projet s'enracine dans une premiere anthropologie qu'on qualifiera d'abstraite en ce qu'elle a pour objet de definir l'essence contradictoire de l'homme. Enfin, Pascal en vient a envisager les hommes dans leur existence meme. Les deux themes de la gloire (humaine) et du divertissement permettent de caracteriser cette anthropologie existentielle, au terme de laquelle s'eclaire la puissance d'alienation de l'imagination. L'analytique de l'existence humaine constitue des lors ce qu'on appellera la seconde anthropologie de Pascal. (shrink)

"Certitude" : le Mémorial -- "Quelle morale la raison devrait dicter sans la lumière de la foi" : l'entretien de M. Pascal avec M. de Sacy -- "La vérité hors de la charité" : du mystère de la pénitence -- "N'y a-t-il point une vérité substantielle?" : infini, rien -- "Qu'on ne prétende pas subtiliser" : les Écrits sur la grâce -- "La maxime de la médisance" : la XVIe Provinciale -- "Ce qui achève notre impuissance" : disproportion de l'homme (...) -- "De nouvelles lumières sur la religion" : la Vie de M. Pascal et De la vraie religion -- De vera religione -- Annexe : "Le chosisme" : Étienne Gilson et Pascal -- "Un portrait porte absence et présence" : De la vraie religion -- "Dans l'ennui" : du divertissement -- "Nous ne nous tenons jamais au temps présent" : du divertissement -- "En lui vous êtes remplis" : la Prière pour le bon usage des maIadies -- L'amitié "sans attachement" : la Vie de M. Pascal. (shrink)

This article examines the philosophical and theological nuances in the works of Étienne Pascal and Étienne Noël, focusing on their interpretations of Saint Augustine and Jean Duvergier de Hauranne. It explores the concept of antithesis (ἀντίθεσις) in both rhetorical and philosophical contexts, drawing upon Platonic and Aristotelian texts. The article highlights the use of antithesis in Augustine’s explanation of evil and its integration into the universal order, connecting this to 17th-century French thought, especially in relation to Blaise Pascal’s ideas on (...) rhetoric. A critical analysis of Étienne Pascal’s letter to Father Noël is presented, emphasizing his understanding of rhetorical figures, notably metaphor and antithesis, and their theological implications. The discussion extends to Saint-Cyran’s interpretation of Augustine, particularly concerning ecclesiastical guidance and priesthood preparation. The article concludes by underscoring the complex interplay between language, thought, and faith in these historical contexts. (shrink)

Le dernier ouvrage d’Antony McKenna, intitulé Pascal et son libertin, présente en une synthèse claire et précise les résultats de plus de trente années consacrées par l’auteur aux études pascaliennes et à l’étude de la pensée libertine de la période classique. Auteur d’une thèse d’État publiée sous le titre De Pascal à Voltaire : le rôle des Pensées de Pascal dans l’histoire des idées entre 1670 et 1734 puis de plus d’une centaine d’études d’histoire de la philosophie du XVIIe et (...) du XVIIIe si... (shrink)

The books of Pascal Quignard present themselves as a hunt for the invisible. The ambition that lies at their heart seems particularly compatible with a phenomenological approach. Indeed, this literary intuition – this “suspicion” in the words of Quignard – hinges on the nature and value of representation. This article tries to read the entire work of Quignard through the phenomenological lens. The elucidation of phenomenality is accomplished here through the steps of a process that leads to the very condition (...) of vision. Once the essence of representation is established as a “predation”, the literary writing of the author reveals it as related to an absent, invisible prey. Through the successive and ascending figures of idolatry, love, art and contemplation, can then start a route to invisibility, which is a true pedagogy of seeing. This quest, conceivable as a learning process through which literature finds its ultimate aim, finally leads to a renewed understanding of the concept of representation. (shrink)

"Réfléchir à la réflexion, penser la pensée et philosopher sur la philosophie, voilà ce que l'on propose de faire ici. Cette démarche est moins formelle qu'il n'y paraît, car interroger la nature et les exigences de la pensée philosophique engage toute une philosophie. Une philosophie qui n'est pas dupe d'elle-même et qui commence par examiner sa propre finitude. "La dernière démarche de la raison, c'est de connaître qu'il y a une infinité de choses qui la surpassent. Elle est bien faible (...) si elle ne va jusque là", disait Pascal. Nous montrons dans un esprit proche que la réflexion est d'autant plus puissante qu'elle reconnaît son impuissance, comme la philosophie authentique doit se savoir doublement bornée, par la pensée scientifique d'une part, et par la pensée mystique d'autre part. Il ne s'agit pas de rabaisser la philosophie, mais au contraire de lui permettre de comprendre ce qui la comprend et de trouver sa juste place dans le champ intellectuel."--Page 4 of cover. (shrink)

Focusing on Descartes’ striking phrase “real things” in Discours de la methode, and on the one of “reality of things” written by Pascal in his Pensées, this paper aims to shed light on Cartesian co...

Analyse critique de deux ouvrages récents dans lesquels Vincent Descombes critique les conceptions cartésiennes et matérialistes contemporaines de l'esprit, d'un point de vue néo-wittgensteinien. Contrairement à ce qu'il croit ni le holisme ni l'externalisme qu'il avance ne sont incompatibles avec une conception causaliste du mental et une forme plus complexe de naturalisme. A critical analysis of two recent books by Vincent Descombes, where he criticizes contemporary Cartesian and materialistic theories of the mind from a neo-Wittgensteinian standpoint. Contrary to (...) what he claims, neither holism nor externalism can be incompatible with a causalist view of the mental and a more sophisticated form of naturalism. (shrink)

L'originalité de l'interprétation pascalienne des trois concupiscences selon 1 Jn 2, 16 est double : d'une part, il ne s'agit plus des plaisirs des sens; Pascal abandonne la doctrine janséniste de la délectation, elle-même fondée sur une théorie de l'imitation; d'autre part, cette concupiscence n'est pas tant l'amour du pouvoir que l'amour de la richesse, en tant qu'elle particularise. Le renversement des trois concupiscences en « trois ordres de choses » ne se comprend que si l'on voit que toute la (...) méditation pascalienne est orientée vers sa fin, le quaternaire sapientiel fourni par 1 Cor 1, 30. Ainsi la lecture nécessairement théologique du § 933 interdit d'en faire un modèle partout exportable et de lui attribuer une fonction architectonique pour l'ensemble de l'Apologie. The originality of the Pascalian interpretation of the three kinds of concupiscence according to 1 John 2: 16 is twofold: on the one hand, what is aimed at no longer is the pleasures of the senses; Pascal gives up the Jansenist doctrine of delectation, which was itself founded on a theory of imitation; on the other hand, concupiscence thus redefined no longer is a yearning for power, and becomes a yearning for riches, insofar as it consists in intemizing. The reversal of these three kinds of concupiscence into the « three orders of things » can be understood only if one realises that the whole Pascalian meditation is directed towards its end, namely the sapiential quaternary provided in 1 Corinthians 1: 30. Thus, the necessarily theological reading of § 933 makes it impossible to see it as a universally pertinent model or to ascribe to it an architectonic role in the structure of the Apologia. (shrink)

Depuis près de quarante ans, Pierre Manent trace une voie originale et féconde. Ses livres interrogent les formes politiques qui donnent sens à l'expérience historique, de la cité grecque aux nations européennes, en passant par l'Empire romain et l'Eglise chrétienne. Cet ouvrage, le premier entièrement consacré à Pierre Manent, aborde les grands thèmes de son oeuvre, autour de trois axes: la philosophie, la politique et la religion. Il examine également les principales étapes de la pensée politique : Aristote, Machiavel, Pascal, (...) Tocqueville... L'histoire et la philosophie politique éclairent les enjeux du présent, en particulier la crise de la démocratie et de la nation en Europe. Pour Pierre Manent et ceux qui s'en inspirent, la politique constitue le fait générateur des sociétés humaines. Elle façonne l'humanité de l'homme, qui se réalise dans la vie en commun. Aller vers la politique, c'est aller vers l'âme. Une incitation à lire et relire une oeuvre forte et pénétrante. (shrink)

It has recently been argued that normative considerations play an important role in causal cognition. For instance, when an agent violates a moral rule and thereby produces a negative outcome, she will be judged to be much more of a cause of the outcome, compared to someone who performed the same action but did not violate a norm. While there is a substantial amount of evidence reporting these effects, it is still a matter of debate how this evidence is to (...) be interpreted. In this paper, we engage with the three most influential classes of explanations, namely, (a) the Norm‐Sensitive Cognitive Process View, (b) the Normative Concept View, and (c) the Pragmatics View. We will outline how these theories explain the empirical results and in what ways they differ. We conclude with a reflection on how well these strategies do overall and what questions they still leave unanswered. (shrink)

The omission effect, first described by Spranca and colleagues, has since been extensively studied and repeatedly confirmed. All else being equal, most people judge it to be morally worse to actively bring about a negative event than to passively allow that event to happen. In this paper, we provide new experimental data that challenges previous studies of the omission effect both methodologically and philosophically. We argue that previous studies have failed to control for the equivalence of rules that are violated (...) by actions and omissions. Once equivalent norms are introduced, our results show that the omission effect is eliminated, even if the negative outcome of the behavior is foreseen and intended by the agent. We show that the omission effect does not constitute a basic, moral disposition but occurs exclusively in complex moral situations. Building on these empirical results, we cast doubt onto two influential explanations of the omission effect, the Causal Relevance Hypothesis and the Overgeneralization Hypothesis, and provide a novel explanation of the phenomenon. Furthermore, we discuss various ramifications of the interplay between our understanding of omissions and legal systems. (shrink)

Thick terms and concepts, such as honesty and cruelty, are at the heart of a variety of debates in philosophy of language and metaethics. Central to these debates is the question of how the descriptive and evaluative components of thick concepts are related and whether they can be separated from each other. So far, no empirical data on how thick terms are used in ordinary language has been collected to inform these debates. In this paper, we present the first empirical (...) study, designed to investigate whether the evaluative component of thick concepts is communicated as part of the semantic meaning or by means of conversational implicatures. While neither the semantic nor the pragmatic view can fully account for the use of thick terms in ordinary language, our results do favour the semanticist interpretation: the evaluation of a thick concept is only slightly easier to cancel than semantically entailed content. We further discovered a polarity effect, demonstrating that how easily an evaluation can be cancelled depends on whether the thick term is of positive or negative polarity. (shrink)

L’absurdité du monde et l’inquiétude face au sens de l’existence semblent être des affects négatifs. Par un dialogue entre Albert Camus et Jacques Lavigne, nous tenterons d’explorer le caractère créatif de ces affects. Camus et Lavigne partent d’une critique du matérialisme et de l’idéalisme afin d’ancrer leur théorie dans l’existence , en pensant conjointement les idées et la matérialité. Ils découvrent le rôle précieux de l’absurde et de l’inquiétude. Ces affects agissent comme vecteurs de l’action humaine et permettent d’initier le (...) sujet à la solidarité. Néanmoins, la société est organisée de telle manière que le sujet doit constamment s’opposer à la possibilité d’une neutralisation de ses affects. En ce sens, rester inquiet et conscient de l’absurdité de l’existence appelle une résistance du sujet. (shrink)

This analysis shows the common critique of representation suggested by the fluid metaphor in feminist theory and literature. The poetics of theory and the poetics of literature thus flow together into a metaphorical poetics of the fluid as a utopian form and space that subverts patriarchal language and textually undermines artificial divisions among the very genres of theory and literature that describe it.Ingeborg Bachmann’s fragmentary novel Der Fall Franza reconstructs the crisis and death of its eponymous young Austrian female protagonist, (...) who has been psychologically destroyed by her psychologist husband and who convinces her geologist brother to take her on a research trip to Egypt. One of the first events.. (shrink)

This paper critically discusses recent objections that have been raised against the contextual understanding of fundamental physical objects advocated by non-eliminative ontic structural realism. One of these recent objections claims that such a purely relational understanding of objects cannot account for there being a determinate number of them. A more general objection concerns a well-known circularity threat: relations presuppose the objects they relate and so cannot account for them. A similar circularity objection has also been raised within the framework of (...) the weak discernibility claims made in the last few years about quantum particles. We argue that these objections rely either on mere metaphysical prejudice or on confusing the logico-mathematical formalism within which a physical theory is formulated with the physical theory itself. Furthermore, we defend the motivations for taking numerical diversity as a primitive fact in this context. (shrink)

L’inégalité est une thématique sociale, abordée de façon récurrente dans les médias. Appliquant une approche de « sémantique discursive », nous examinerons l’usage d’inégalité(s) dans le discours de presse en circonscrivant les principales dimensions sémantiques du nom à travers ses fonctionnements préférentiels en cotexte, étroit ou élargi. Après quelques questionnements sémantico-référentiels autour du mot, l’étude du corpus – constitué d’articles issus des journaux Le Monde, Libération et Le Figaro – montrera qu’inégalité(s) fonctionne, à la fois, comme un lieu d’observation, d’évaluation (...) et de revendication. L’analyse conduit également à penser que l’usage partagé et consensuel du segment lutte contre les inégalités dans le corpus fait apparaître une forme de « langue de bois ». (shrink)