Richard Polt takes a fresh approach to Heidegger’s thought during his most politicized period, and works toward a philosophical appropriation of his most valuable ideas. Polt shows how central themes of the 1930s—such as inception, emergency, and the question “Who are we?”—grow from seeds planted in Being and Time and are woven into Heidegger’s political thought. Working with recently published texts, including Heidegger’s Black Notebooks, Polt traces the thinker’s engagement and disengagement from the Nazi movement. He critiques Heidegger for (...) his failure to understand the political realm, but also draws on his ideas to propose a “traumatic ontology” that understands individual and collective existence as identities that are always in question, and always remain exposed to disruptive events. Time and Trauma is a bold attempt to gain philosophical insight from the most problematic and controversial phase of Heidegger’s thought. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Women Are Up to Something: How Elizabeth Anscombe, Philippa Foot, Mary Midgley, and Iris Murdoch Revolutionized Ethics by Benjamin J. B. LipscombAmy Gilbert RichardsLIPSCOMB, Benjamin J. B. The Women Are Up to Something: How Elizabeth Anscombe, Philippa Foot, Mary Midgley, and Iris Murdoch Revolutionized Ethics. New York: Oxford University Press, 2022. xxx + 326 pp. Cloth, $27.95In The Women Are Up to Something, Lipscomb demonstrates in form (...) and content the inextricable link between philosophical theory and personal story and character. The book tells two stories: "first, a story [End Page 148] about four women, their overlapping friendships, and their struggle to establish themselves as philosophers in an often-hostile context; second, a story about two conflicting approaches to ethics." These two stories connect through the role these women played in the development of the second of the conflicting approaches—a challenge to the mid-twentieth-century Oxbridge orthodoxy in metaethics, what Lipscomb later calls a "minority report."Chapter 1 centers on the fact–value divide. The consequence of this divide for ethics lies in its banishment of all evaluative terms from the realm of possible facts, thereby demoting them to matters of "opinion." Lipscomb here offers a genealogy of the divide. He also introduces the insight that will become the seed of the minority report: The picture of the world offered by the fact-value divide is just that, a picture. Bringing to light the deep background pictures that undergird our understanding of the world is one of the most difficult intellectual tasks. But the picture rooted in the fact–value divide includes the claim that the divide itself is simply a "fact"—not a picture at all, and therefore not contestable. Lipscomb labels this view "the Dawkins' sublime."The next three chapters continue the work of stage-setting. Chapter 2 immerses us in the Oxford of the women's undergraduate years—an Oxford temporarily but dramatically altered by World War II, where female students made up a much larger percentage of the undergraduate population than was usual, and where professors were in a new way open to mentoring women. Chapter 3 briefly recounts all four childhoods, lived in the aftermath of the first World War. Chapter 4 returns to Oxford and narrates the graduate degrees of the four women. It also offers a perceptive primer on the history of analytic ethics, culminating in the state of the field at the point when the women were on the cusp of entering it—the precise shape of the approach to ethics the women would eventually abjure.Each of the next four chapters traces the development of the mature philosophy of one of the four women—in order: Murdoch, Anscombe, Foot, and Midgley. Despite deep differences among their philosophical and theological outlooks, they all four came to defend a version of the thesis, commonplace in ancient and medieval philosophy, that there are things that are good for human beings qua human being, that our moral lives are largely a matter of seeing and responding—well or poorly—to these elements of the human good that are given as part of our nature. In other words, there are facts about values. We in crucial ways discover rather than invent morality.The last chapter serves as an epilogue to both stories: It traces the ways in which the writing and lives of these four women produced a decisive change in the landscape of Anglo-American philosophy. Lipscomb notes which strains in contemporary Anglo-American philosophy owe their existence to the minority report. Figures like Korsgaard feature as contemporary representatives of an ethics grounded in the fact–value [End Page 149] divide. Figures like MacIntyre and Hursthouse feature as inheritors of the philosophical legacy of the book's heroines.In this final chapter Lipscomb also offers brief portraits of the later life and death of each of the women in turn. At the end of the final portrait, the book rounds to a poetic close—not offering a final philosophical statement but reflecting on the fruits of friendship and the power of its legacy for those who come after.It is difficult to pin down Lipscomb's precise philosophical... (shrink)

In Body and Story Richard Terdiman explores the tension between what seem two fundamentally different ways of understanding the world: as physical reality and as representation in language. In demonstrating the complicated relationship between these two perspectives, he also offers a new approach to the problem of conflicts between irreconcilable but equally compelling theoretical ideas. Enlightenment rationalism is most often understood as maintaining that words can meaningfully refer to and grasp things in the material world, while Postmodernism famously argues (...) that nothing exists outside of language. Terdiman challenges this clean distinction, finding the early seeds of Postmodern doubt in the Enlightenment, and demonstrating the stubborn resistance of material reality -- particularly that of the body -- to language even today. Building on readings of works by 18th-century encyclopedist Denis Diderot and contemporary philosopher-icon Jacques Derrida, Terdiman argues that despite their genuine and profound opposition, a constant negotiation or mutual interrogation has always been taking place between these two world-views, even as the balance at times shifts to one side or the other. In analyzing these shifts he proposes a new model for understanding how seemingly unabridgeable theories legitimately coexist in our intellectual conception of the world, and he suggests a new ethics for managing this coexistence. (shrink)

When Charles Darwin (1859, 482) wrote in the Origin of Species that he looked to the “young and rising naturalists” to heed the message of his book, he likely had in mind individuals like Ernst Haeckel (1834-1919), who responded warmly to the invitation (Haeckel, 1862, 1: 231-32n). Haeckel became part of the vanguard of young scientists who plowed through the yielding turf to plant the seed of Darwinism deep into the intellectual soil of Germany. As Haeckel would later observe, (...) the seed flourished in extremely favorable ground. The German mind, he would write (1868), was predisposed to adopt the new theory. The great philosopher Immanuel Kant (1724- 1804), for instance, was on the verge of accepting a transmutational view in his Third Critique (1790; 1957, 538-39), though he stepped gingerly back from the temptation. Johann Wolfgang von Goethe (1749-1832), about the same time, dallied with transmutational ideas, at least Haeckel would convince Darwin that the Englishman had an illustrious predecessor. Jean-Baptiste de Lamarck’s (1744-1829) conceptions had taken hold among several major German thinkers in the first few decades of the nineteenth century in a way they had not in England and France. Among those ready to declare themselves for the new dispensation was Rudolf Virchow (1821-1902), Haeckel’s teacher at Würzburg—though, this very political scientist would prove Haeckel’s nemesis later in the century. So Haeckel’s estimate of the ripeness of German thought was not off the mark. Darwinism took hold in the newly unified land, though not without some struggle; but at last it became the dominant view in the biological sciences. But with its success did it foster the malign racist ideology that transfixed Adolf Hitler (1889-1945)? (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 42.3 (2004) 297-326 [Access article in PDF] Wittgenstein, German Organicism, Chaos, and the Center of Life Richard Mcdonough No supposition seems to me more natural than that there is no process in the brain correlated with associating or with thinking; so that it would be impossible to read off thought processes from brain processes. I mean this: if I talk or write, (...) there is, I assume, a system of impulses going out from my brain and correlated with my spoken or written thoughts. But why should the system continue further in the direction of the center. Why should this order not proceed, so to speak, out of chaos? The case would be like the following-certain kinds of plants multiply by seed, so that a seed always produces a plant of the same kind as that from which it was produced—but nothing in the seed corresponds to the plant which comes out of it—this can only be done from the history of the seed. So an organism might come into being out of something quite amorphous, as it were, causelessly; and there is no reason why this should not really hold for our thoughts, and hence for our talking and writing. L. Wittgenstein, Zettel §608 Paragraph 608 of Zettel is one of the most remarkable passages in Wittgenstein, for it presents a more metaphysical view than one would associate with his later philosophy.1 [End Page 297] Despite Wittgenstein's well known opposition to metaphysics,2 Z §608 clearly endorses a doctrine of emergence, the view, that the order in our language and thought "arises" out of "chaos" or "nothing." The general idea in emergentism is that certain kinds of wholes, notably, organisms, are "greater than the sum of their parts."3 Although emergentism has suffered from neglect and abuse for a half century, it has recently become a live issue.4Klee, Kim, and McLaughlin emphasize the kind of emergence which involves "downward causation," the view that the emergent whole causally influences the behavior of its own parts.5 Such emergentism asserts that there is an "explanatory gap" between an organism's characteristics and its mechanical structure,6 where this gap is a matter of ontology rather than mere ignorance of the causes. The present paper argues that Wittgenstein's doctrine of emergence is central to his later philosophies of language and mind. The common view that Wittgenstein's later philosophy is primarily negative has proved a liability for Wittgenstein.7 Cognitive scientists respond that even if there are serious problems with their views, [End Page 298] "Remotely plausible theories are better than no theories at all."8 But Wittgenstein's remark at PI §109 that philosophy should not offer theories has been misunderstood. For Wittgenstein, the paradigm of a theory is mechanics (LAC28-29), and it is not the job of philosophy to explain the phenomena by adverting to hidden mechanisms (PI §435). But philosophy may offer a different kind of positive account, the kind of descriptive account appropriate to emergent organic phenomena.9 According to Z §608, this is a description of the phenomena as it emerges in a history. In order to appreciate Wittgenstein's emergentism, it is necessary to have the correct interpretation of the words "center" and "chaos" in Z §608. Many commentators take it as obvious that by "the center," Wittgenstein means the neural center.10 For in modern neuroscience, it is natural to view the brain as the control center of the organism. Wooldridge, Armstrong, Popper, Rose, Fodor, Dennett, Gillett, Greenfield, and Clark, all use "center" in this way.11Given the modern view, called "central state materialism" as background,12 Z §608 seems to claim, first, that the order of our thought and language cannot be [End Page 299] traced to the neural center, and, second, that intelligence must arise out of neural "chaos." Thus, McGinn thinks Wittgenstein is suggesting that the brain might turn out to be oatmeal.13 But careful attention to... (shrink)

This chapter contains section titled: The Relation of Genotype to Phenotype Statistical Approaches to the Study of Quantitative Characters Problems Raised by Statistical Methodologies Making Quantitative Trait Genes Real Bibliography.

There are a growing number of examples where naturally occurring mutations disrupt an established physiological or developmental pathway to yield a new condition that is evolutionary favored. Asexual reproduction by seed in plants, or apomixis, occurs in a diversity of taxa and has evolved from sexual ancestors. One form of apomixis, diplospory, is a multi‐step development process that is initiated when meiosis is altered to produce an unreduced rather than a reduced egg cell. Subsequent parthenogenetic development of the unreduced (...) egg yields genetically maternal progeny. While it has long been apparent from cytological data that meiosis in apomicts was malfunctional or completely bypassed, the genetic basis of the phenomenon has been a long‐standing mystery. New data from genetic analysis of Arabidopsis mutants1 in combination with more sophisticated molecular understanding of meiosis in plants indicate that a weak mutation of the gene SWI, called DYAD, interferes with sister chromatid cohesion in meiosis I, causes synapsis to fail in female meiosis and yields two unreduced cells. The new work shows that a low percentage of DYAD ovules produce functional unreduced egg cells (2n) that can be fertilized by haploid pollen (1n) to give rise to triploid (3n) progeny. While the DYAD mutants differ in some aspects from naturally occurring apomicts, the work establishes that mutation to a single gene can effectively initiate apomictic development and, furthermore, focuses efforts to isolate apomixis genes on a narrowed set of developmental events. Profitable manipulation of meiosis and recombination in agronomically important crops may be on the horizon. BioEssays 30:798–801, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Following the rediscovery of Mendelian genetics, food supply pressures and the rapid expansion of crop varieties with defined performance characteristics, international systems were set up throughout the 20 C to regulate the trade of seed, the protection of intellectual property and the sale of productive varieties of key agricultural crops. These systems are a highly connected but largely linear set of processes. System changes are slow to be adopted due to the cascade of effects that structural alteration would have (...) globally. Multi-omic technologies and the subsequent proliferation of data types used within modern breeding, offer the possibility to gain deeper insights into the performance characteristics of varieties. Current integration of data, standards and ownership structures limit their applications for wider purposes, both private and public. We explore how data within and between breeding programmes and the varietal approval and monitoring processes could be made FAIR. We examine what role expanded or aligned programmes of data collection and expanded trait evaluation at the point of varietal registration and evaluation, as well as on farm could have in ensuring the best linkage of public and private data to address some of the challenges society faces over the next 30 years with the required, rapid transition to sustainable agricultural systems. (shrink)

No supposition seems to me more natural than that there is no process in the brain correlated with associating or with thinking; so that it would be impossible to read off thought processes from brain processes. I mean this: if I talk or write, there is, I assume, a system of impulses going out from my brain and correlated with my spoken or written thoughts. But why should the system continue further in the direction of the center? Why should this (...) order not proceed, so to speak, out of chaos? The case would be like the following—certain kinds of plants multiply by seed, so that a seed always produces a plant of the same kind as that from which it was produced—but nothing in the seed corresponds to the plant which.. (shrink)

The earlier Life of Locke, by Lord King, had consisted largely of an assemblage of Locke's own letters and manuscripts, of great value to the historian, but of rather less interest to the student of Locke's philosophy. Fox Bourne's biography, by contrast, concentrates on Locke the philosopher, and seeks to place his philosophical works in the context of his life. Fox Bourne thus describes Locke's studies at Oxford, his distaste for scholasticism, the discovery of Descartes' Meditations, and the role of (...) his medical and scientific interests and of his friendships with Boyle, Sydenham and Newton, in shaping his thought. Although the seeds of the Essay may have been sown as early as 1670, Fox Bourne admits, it was during Locke's exile in Holland between 1683 and 1689, and under the influence of such Dutch friends as Le Clerc, that the great work really took shape. At the heart of the work, we are told, is the critique of revelation that occupies pride of place in Book Four - Locke's overriding concern was to articulate a rationally defensible and universally acceptable version of Christianity. (shrink)

In 1949, the Department of Philosophy at the University of Manchester organized a symposium “Mind and Machine” with Michael Polanyi, the mathematicians Alan Turing and Max Newman, the neurologists Geoff rey Jeff erson and J. Z. Young, and others as participants. Th is event is known among Turing scholars, because it laid the seed for Turing’s famous paper on “Computing Machinery and Intelligence”, but it is scarcely documented. Here, the transcript of this event, together with Polanyi’s original statement and (...) his notes taken at a lecture by Jeff erson, are edited and commented for the fi rst time. Th e originals are in the Regenstein Library of the University of Chicago. Th e introduction highlights elements of the debate that included neurophysiology, mathematics, the mind-body-machine problem, and consciousness and shows that Turing’s approach, as documented here, does not lend itself to reductionism. (shrink)

The avocado (Persea americana) is a major crop commodity worldwide. Moreover, avocado, a paleopolyploid, is an evolutionary “outpost” among flowering plants, representing a basal lineage (the magnoliid clade) near the origin of the flowering plants themselves. Following centuries of selective breeding, avocado germplasm has been characterized at the level of microsatellite and RFLP markers. Nonetheless, little is known beyond these general diversity estimates, and much work remains to be done to develop avocado as a major subtropical‐zone crop. Among the goals (...) of avocado improvement are to develop varieties with fruit that will “store” better on the tree, show uniform ripening and have better post‐harvest storage. Avocado transcriptome sequencing, genome mapping and partial genomic sequencing will represent a major step toward the goal of sequencing the entire avocado genome, which is expected to aid in improving avocado varieties and production, as well as understanding the evolution of flowers from non‐flowering seed plants (gymnosperms). Additionally, continued evolutionary and other comparative studies of flower and fruit development in different avocado strains can be accomplished at the gene expression level, including in comparison with avocado relatives, and these should provide important insights into the genetic regulation of fruit development in basal angiosperms. BioEssays 30:386–396, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

In plants, successful sexual reproduction and the ensuing development of seeds and fruits depend on flowering at the right time. This involves coordinating flowering with the appropriate season and with the developmental history of the plant. Genetic and molecular analysis in the small cruciform weed, Arabidopsis, has revealed distinct but linked pathways that are responsible for detecting the major seasonal cues of day length and cold temperature, as well as other local environmental and internal signals. The balance of signals from (...) these pathways is integrated by a common set of genes to determine when flowering occurs. Excitingly, it has been discovered that many of these same genes regulate flowering in other plants, such as rice. This review focuses on recent advances in how three of the signalling pathways (the day‐length, vernalisation and autonomous pathways) function to control flowering. BioEssays 26:363–373, 2004. © 2004 Wiley‐Liss, Inc. (shrink)

As a study of Hobbes and Rousseau which shows that the seeds of totalitarianism are ingredient in their individualism, this book is a success. Hobbes proceeds from individual natural rights of men to the primacy of sovereign political will with all its concomitant dangers of the total subordination of the individual to the power of the sovereign. Rousseau, unlike Hobbes, attempts to preserve man’s liberty in society. By the social contract man exchanges his natural liberty for civil liberty. But the (...) state then becomes an absolute, ‘universally compulsive power’; the General Will is always right and so potentially totalitarian. The author does well to point up these sometimes overlooked facets of Hobbes and Rousseau, and he argues well that in their systems totalitarianism can spring up in the garden of individualism. (shrink)

Richard Matheson seeded several weird fish in the deep and dark waters of the American myth pool, not least as a prominent screenwriter for the legendary 1960s TV series The Twilight Zone. I Am Legend, a post-apocalyptic science fiction/horror novel, published in 1954 and set in 1976, remains one of his best known works.1 It shows up persistently on "Best of Horror" lists and is generally regarded as a milestone in modern Gothic fiction. What is it about this novel (...) that has invested it with canonical status? It tells a surpassingly bleak story, one that seems to encode very specific and largely outdated cultural anxieties. And as prophecy, it falls rather flat: Matheson depicts a vampire holocaust, and the .. (shrink)

In late August 2002, a general practitioner in London, Dr Bhagat Singh Makkar, 62, was struck off the medical register after he was discovered to have bragged to an undercover journalist about being able to obtain a kidney from a live donor in exchange for a fee. He told the journalist, who posed as the son of a patient with renal failure: “No problem, I can fix that for you. Do you want it done here, do you want it done (...) in Germany or do you want it done in India?” The price he quoted included payment to the donor and “my administration costs”. Dr Makkar said he regretted giving “stupid answers” to the journalist. He had been “tired, confused, and upset after a long day dealing with emotional patients”.1Deliberation about ethics is often muddied by the personalities involved in a particular issue. Many people are uninspired by Richard Seed or Jack Kevorkian. This contaminates their view about the much broader and important issues such as cloning or euthanasia that Seed and Kevorkian, whom some people might describe as mavericks, have shoved their finger in.Discussion of the sale of organs is …. (shrink)

In February 1997, following the announcement that the Roslin Institute in Scotland had successfully cloned a sheep by means of cell-nuclear transfer, US President Clinton requested the National Bioethics Advisory Commission to review legal and ethical issues of cloning and to recommend federal actions to prevent abuse. In the meantime he directed the heads of executive departments and agencies not to allocate federal funds for ‘cloning human beings’. The Commission consulted with members of relevant academic disciplines and other professions, representatives (...) of interest groups and members of the general public, and received written submissions. Unsurprisingly, given the prospect of human cloning and the sensational announcement in January 1998 by the American physicist-cum-embryologist Richard Seed that he would aim to clone himself, public debate in the US has been fairly voluble. (shrink)

Artificial intelligence, the "science and engineering of intelligent machines", still has yet to create even a simple "Advice Taker" [McCarthy, 1959]. We have previously argued [Waser, 2011] that this is because researchers are focused on problem-solving or the rigorous analysis of intelligence (or arguments about consciousness) rather than the creation of a "self" that can "learn" to be intelligent. Therefore, following expert advice on the nature of self [Llinas, 2001; Hofstadter, 2007; Damasio, 2010], we embarked upon an effort to design (...) and implement a self-understanding, self-improving loop as the totality of a (seed) AI. As part of that, we decided to follow up on Richard Dawkins' [1976] speculation that "perhaps consciousness arises when the brain's simulation of the world becomes so complete that it must include a model of itself" by defining a number of axioms and following them through to their logical conclusions. The results combined with an enactive approach yielded many surprising and useful implications for further understanding consciousness, self, and "free-will" that continue to pave the way towards the creation of safe/moral autopoiesis. (shrink)

Slurs are words with a well-known tendency to conjure up painful memories and experiences in members of their target communities. Owing to this tendency, it’s widely agreed that one ought to exercise considerable care when even mentioning a slur, so as to avoid needlessly inflicting distressing associations on members of the relevant group. This paper argues that this tendency to evoke distressing associations is precisely what makes slurs impactful verbal weapons. According to the ballistic theory, slurs make such potent insults (...) because they enable their users to maliciously inflict noxious associations on members of their target groups. To motivate this theory, I demonstrate its ability to explain a number of facts about slurs’ offensiveness that pose formidable difficulties for competing theories of slurs. I argue that the ballistic theory not only explains why slurs make such explosively impactful terms of abuse, but also why: uses of slurs can provoke offense even when they aren’t interpreted as expressions of the speaker’s racist attitudes; and why mentions of slurs are inoffensive in some contexts, but in other contexts, warrant a level of offense every bit as severe as that warranted by weaponized uses. I conclude with a brief discussion of a practical application of the ballistic theory. I demonstrate that the theory has an important consequence for legislative efforts to regulate and punish weaponized uses of slurs. (shrink)

The repertory grid method was used to determine what terminology respondents use to distinguish between different applications of genetic engineering drawn from food- related, agricultural, and medical applications. Respondents were asked to react to fifteen applications phrased in general terms, and results compared with a second study where fifteen more specific applications were used as stimuli. Both sets of data were submitted to generalized Procrustes analysis. Applications associated with animals or human genetic material were described as causing ethical concern, being (...) unnatural, harmful, and dangerous. Those involving plants or microorganisms were described as beneficial, progressive, and necessary. The results were validated in survey research, which indicated that general applications ofgenetic engineering were perceived as either positive or negative, whereas specific applications were more highly differentiated in perceptual terms. The results imply that the public debate about genetic engineering must take due account of the complexity of public concerns. (shrink)

This paper compares and contrasts relational quantum mechanics with a pragmatist view of quantum theory. I first explain important points of agreement. Then I point to two problems faced by RQM and sketch DP?s solutions to analogous problems. Since both RQM and DP have taken the Born rule to require relative facts I next say what these might be. My main objection to RQM as originally conceived is that its ontology of relative facts is incompatible with scientific objectivity and undercuts (...) the evidential base of quantum theory. In contrast DP?s relative facts have all the objectivity we need to accept quantum theory as scientific knowledge. But a very recent modification to RQM has successfully addressed my main objection,bringing the two views into even closer alignment. (shrink)

The more than 40 readings in this anthology cover the most important developments of the past six decades, charting the rise and decline of logical positivism ...

In the absence of empirical confirmation, scientists may judge a theory's chances of being viable based on a wide range of arguments. The paper argues that such arguments can differ substantially with regard to their structural similarly to empirical confirmation. Arguments that resemble empirical confirmation in a number of crucial respects provide a better basis for reliable judgement and can, in a Bayesian sense, amount to significant \textit{non-empirical} confirmation. It is shown that three kinds of non-empirical confirmation that have been (...) specified in earlier work do satisfy those conditions. (shrink)

. Moral systems are described as systems of indirect reciprocity, existing because of histories of conflicts of interest and arising as outcomes of the complexity of social interactions in groups of long‐lived individuals with varying conflicts and confluences of interest and indefinitely iterated social interactions. Although morality is commonly defined as involving justice for all people, or consistency in the social treatment of all humans, it may have arisen for immoral reasons, as a force leading to cohesiveness within human groups (...) but specifically excluding and directed against other human groups with different interests. (shrink)

The concept of self-control is incorporated in a theory of individual intertemporal choice by modeling the individual as an organization. The individual at a point in time is assumed to be both a farsighted planner and a myopic doer. The resulting conflict is seen to be fundamentally similar to the agency conflict between the owners and managers of a firm. Both individuals and firms use the same techniques to mitigate the problems which the conflicts create. This paper stresses the implications (...) of this agency model and discusses as applications the effect of pensions on saving, saving and the timing of income flows, and individual discount rates. (shrink)

Plant genome editing has the potential to become another chapter in the intractable debate that has dogged agricultural biotechnology. In 2016, 107 Nobel Laureates accused Greenpeace of emotional and dogmatic campaigning against agricultural biotechnology and called for governments to defy such campaigning. The Laureates invoke the authority of science to argue that Greenpeace is putting lives at risk by opposing agricultural biotechnology and Golden Rice and is notable in framing Greenpeace as unethical and its views as marginal. This paper examines (...) environmental, food and farming NGOs’ social and ethical concerns about genome editing, situating these concerns in comparison to alternative ethical assessments provided by the Nuffield Council on Bioethics, a key actor in this policy debate. In doing so, we show that participant NGOs and the Nuffield Council on Bioethics share considerable concerns about the social and ethical implications of genome editing. These concerns include choices over problem/solution framing and broader terminology, implications of regulatory and research choices on consumer choice and relations of power. However, GM-engaged NGOs and the Nuffield Council on Bioethics diverge on one important area: the NGOs seek to challenge the existing order and broaden the scope of debate to include deeply political questions regarding agricultural and technological choices. This distinction between the ethical positions means that NGOs provide valuable ethical insight and a useful lens to open up debate and discussion on the role of emerging technologies, such as genome editing, and the future of agriculture and food sovereignty. (shrink)

This unique book clearly explains genetic and neuroimaging research on intelligence and how neuroscience findings may lead to enhancing it.

This book presents the remarkable correspondence between Alfred Schutz and Aron Gurwitsch, emigre philosophers influenced by Edmund Husserl, who fled Europe on the eve of World War II and ultimately became seminal figures in the establishment of phenomenology in the United States. Their deep and lasting friendship grew out of their mutual concern with the question of the connections between science and the life-world. Interwoven with philosophical exchange is the two scholars' encounter with the unfamiliar problems of American academic life—what (...) Gurwitsch called the "passology" of exile. Apart from its brilliant and moving portrait of two distinguished men, the correspondence holds rich significance for current issues in philosophy and the social sciences. (shrink)

Objective: The objective of this study was to evaluate the psychometric properties of the Chinese version of the decision regret scale. Methods: The data of 704 patients who completed the DRSc were used for the analyses. We evaluated the construct, convergent/discriminant, and known-group validity; internal consistency and test–retest reliability; and the item invariance of the DRSc. A receiver operating characteristic curve was employed to confirm the optimal cutoff point of the scale. Results: A confirmatory factor analysis indicated that a one-factor (...) model fits the data. The internal consistency and test–retest reliability [intraclass correlation coefficient = 0.71] of the DRSc were acceptable. The DRSc demonstrated unidimensionality and invariance for use across the sexes. It was confirmed that an optimal cutoff point of 25 could discriminate between patients with high and low decisional regret during clinical practice. Conclusion: The DRSc is a parsimonious instrument that can be used to measure the uncertainty inherent in medical decisions. It can be employed to provide knowledge, offer support, and elicit patient preferences in an attempt to promote shared decision-making. (shrink)

The Epicureans, Skeptics, and Stoics practiced philosophy not as a detached intellectual discipline, but as a worldly art of grappling with issues of daily and urgent human significance: the fear of death, love and sexuality, anger and aggression. Like medicine, philosophy to them was a rigorous science aimed both at understanding and at producing the flourishing of human life. In this engagingly written book, Martha Nussbaum maintains that these Hellenistic schools have been unjustly neglected in recent philosophic accounts of what (...) the classical "tradition" has to offer. By examining texts of philosophers committed to a therapeutic paradigm - including Epicurus, Lucretius, Sextus Empiricus, Chrysippus, and Seneca - she recovers a valuable source for current moral and political thought and encourages us to reconsider philosophical argument as a technique through which to improve lives. In describing the contributions of Hellenistic ethics, Nussbaum focuses on each thinker's treatment of the question of emotion. All argued that many harmful emotions are based on false beliefs that are socially taught, and that good philosophical argument can transform emotions, and, with them, both private and public life. Written for general readers and specialists, this book addresses compelling issues ranging from the psychology of human passion through rhetoric to the role of philosophy in public and private life. (shrink)

Organizational ethics and institutional theories are extended by recovering Weberian and Pre-Weberian theorizing that emphasized the joining of ethics and institutional theories. Understanding how ethics and institutional systems influence each other can advance our understanding of the nature and causes of structural organizational ethics issues and help guide potential reforms. We consider the interplay of these elements during the recession of 2008–2009, highlighting how structural ethics problems may have to be addressed at the institutional levels and not solely the individual (...) or organizational levels. (shrink)

In light of recent developments in argumentation theory, we begin by considering the account that Aristotle gives of what he calls sophistical refutations and of the usefulness of being able to recognise various species of them. His diagnosis of one of his examples of the grouping that he labels epomenon is then compared with a very recent account of the matter, which, like Aristotle, calls on us to attribute a mistake or confusion to anyone who uses this kind of argument. (...) From examination of three other examples that Aristotle himself supplies of epomenon, it appears that there are cases of inferences of this kind that we need not, and perhaps cannot, avoid making. The suggestion is made that this is because the whole family of what Peirce calls abductions have important characteristics in common with epomenon. (shrink)

In this essay Rorty argues that care or concern alone is inadequate for dealing with problems of Third World poverty; neither is there likely to be a convenient technological fix. There is no evading the hard decisions that global poverty will require of the rich nations, and there is no way past E. M. Forster’s dictum, in Howard’s End, that “We are not concerned with the very poor. They are unthinkable and only to be approached by the statistician or the (...) poet.” Most of Rorty’s essay focuses on works of Forster demonstrating that, in Rorty’s words, “tenderness only appears... when there is enough money to produce a little leisure, a little time in which to love.... The cash value of the Christian ideal of universal brotherhood has, for the last two centuries, been the conviction that once science and technology have produced enough wealth—and enlightened, unselfish political initiatives have redistributed it—there will be no one left who is incapable of tenderness. All human beings will live in the light; all of them will be possible characters in novels.”. (shrink)

What is strange? Or better, who is strange? When do we encounter the strange? We encounter strangers when we are not at home: when we are in a foreign land or a foreign part of our own land. From Freud to Lacan to Kristeva to Heidegger, the feeling of strangeness--das Unheimlichkeit--has marked our encounter with the other, even the other within our self. Most philosophical attempts to understand the role of the Stranger, human or transcendent, have been limited to standard (...) epistemological problems of other minds, metaphysical substances, body/soul dualism and related issues of consciousness and cognition. This volume endeavors to take the question of hosting the stranger to the deeper level of embodied imagination and the senses. This volume plays host to a number of encounters with the strange. It asks such questions as: How does the embodied imagination relate to the Stranger in terms of hospitality or hostility? How do we distinguish between projections of fear or fascination, leading to either violence or welcome? How do humans "sense" the dimension of the strange and alien in different religions, arts, and cultures? How do the five physical senses relate to the spiritual senses, especially the famous "sixth" sense, as portals to an encounter with the Other? Is there a carnal perception of alterity, which would operate at an affective, prereflective, preconscious level? What exactly do "embodied imaginaries" of hospitality and hostility entail, and how do they operate in language, psychology, and social interrelations? And what, finally, are the topical implications of these questions for an ethics and practice of tolerance and peace? (shrink)

Why did Greek philosophy begin in the sixth century BCE? Why did Indian philosophy begin at about the same time? Why did the earliest philosophy take the form that it did? Why was this form so similar in Greece and India? And how do we explain the differences between them? These questions can only be answered by locating the philosophical intellect within its entire societal context, ignoring neither ritual nor economy. The cities of Greece and northern India were in this (...) period distinctive also by virtue of being pervasively monetised. The metaphysics of both cultures is marked by the projection and the introjection of the abstract, all-pervasive, quasi-omnipotent, impersonal substance embodied in money. And in both cultures this development accompanied the interiorisation of the cosmic rite of passage. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Giulio Castellani (1528-1586): A Sixteenth-Century Opponent of Scepticism CHARLES B. SCH1VHTT THE PROBLEMOF THE ORIGINS of scepticism in early modern philosophy has been a much debated issue. Sanches, Montaigne, Charron, and Bayle all contributed to the milieu which made it possible for the sceptical direction of thought to develop into such a potent force by the time of David Hume. The actual origins of modern scepticism, which seem to (...) go back to a slightly earlier date, lie in the confluence of several different intellectual movements during the early years of the sixteenth century: Christian anti-intellectualism, the reintroduction of the literary remains of the ancient sceptical tradition, the epistemological developments of scholastic nominalism, and certain inherent tendencies of Renaissance humanism. It is in the early decades of the sixteenth century that the seeds which later blossomed forth at the time of Hume originally took root. Hume himself merely reaped the harvest of several hundred years of sceptical preparation? Aside from certain manifestations of doubt which developed out of the epistemological theories of fourteenth-century nominalism, the origins of modern scepticism are generally held to date from the first publication of Sextus Empiricus' ancient summaries of Pyrrhonism during the decade of the 1560's. While it has previously been recognized that at least hints of scepticism were current in the fifteenth and early sixteenth centuries, the implications to be derived from this fact do not seem to have been adequately exploredT I shall not here go into these early manifestations of scepticism in a detailed way. Rather, I shall briefly touch upon a few little-known examples of the influence of ancient scepticism during the Reniassance and, then, I shall focus upon an early and practically neglected attack upon scepticism published before the first printings of Sextus Empiricus' writings. I shall discuss the circumstances of the composition of Giulio Castellani's anti-sceptical work, Adversus Marci TuIlii Ciceronis academicas questiones disi For a recent survey of early modem scepticism see Richard H. Popkin, The History o] Scepticism /tom Erasmus to Descartes (Assen: 1960). Of the large literature which connects scepticism with religious doubt during this period see especially Henri Busson, Les sources et le dgveloppement du rati~nalizme dar~ la litt~rature ]ran~aise de la Renaissance (Paris: 1957) and Don Cameron Allen, Doubt's Boundless Sea (Baltimore: 1964). The di.~cussionof this period seems to be the weakest part of Popkin's excellent book, particularly with regard to the treatment which he gives to Italian thought. See, also, his other articles, especially,"Skepticismand the Counter-Reformation in France," Archiv/fir Re/armationsgeschichte, LI (1960),58-86and "The High Road to Pyrrhonism," American Philosophical Quarterly, II (1965),18--32.In my forthcoming study, Gian]rancesco Pico (1469-1533) and His Critique o/Aristotle, I give a detailed analysis of the major representative of early sixteenthcentury scepticism. [151 16 HISTORY OF PHILOSOPHY putatio (1558), which antedates the first printing of Sextus Empiricus by four years, indicating that scepticism was already widespread enough to provoke an attack from the camp of the dogmatists. Furthermore, I shall analyze Castellani 's arguments in the context of the philosophical views of the mid-sixteenth century. Scepticism in the Early Renaissance Direct knowledge of the major ancient source of scepticism, the already mentioned writings of Sextus Empiricus, was rare throughout the Middle Ages. There are but two known extant Latin manuscripts which date before 1400. s From the fifteenth century we know of two more manuscripts, neither complete in itself, but together containing a significant portion of the extant writings of Sextus. 4 This evidence indicates that Sextus' works were not well known in translation before the first Latin editions of The Oulines o] Pyrrhonism (1562) and of Against the Mathematicians (1569). With the advent of an increased interest in and knowledge of Greek in Western Europe in the fifteenth century, we find a corresponding increase in the number of Greek manuscripts of Sextus Empiricus. Consequently, by the time of the first printings, an appreciable number of copies of his writings were available. Some were brought from the East, but a large number also are attributable to European scribes. 5 We also know that in... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Notes and Discussions METHODOLOGY IN THE HISTORY OF IDEAS: THE CASE OF PIERRE CHARRON Affanities, influences, borrowings, innovations, traditions, consistency--these are some of the key concepts of the time-honored and probably still dominant approach to the history of ideas. Scholars who seek to understand and interpret the philosophy and literature of the past in these terms tend to pay little attention to the social and institutional factors which constituted (...) the working conditions under which the ideas were conceived, articulated and disseminated; and it is precisely on those grounds that the traditional school has been increasingly challenged, over the past several decades, by historians (myself among others) who are convinced that, apart from their social context, the ideas themselves are virtually incomprehensible. A recent article on Pierre Charron by Maryanne Cline Horowitz may serve to illustrate some of the questions raised by these differences in method. At the close of her article, Horowitz explains the assumptions upon which she has conducted her investigation. Citing Peter Gay's interpretation of Ernst Cassirer, she affirms that "the critic begins the process of understanding a philosopher's work by searching for a dynamic center of thought. He must regard doctrines not as a series of discrete positions but as facets of a single point of view. The critic's equipment must therefore include the gift of empathy: he must sympathetically enter--indeed, relive---the thinker's world of ideas.''1 Following her own insight into the spirit of De la sagesse, and supporting it, of course, with a display of textual evidence, Horowitz argues that Richard Popkin was wrong to lay exclusive stress upon Charron's rejection of Aristotelian epistemology from the perspective of Pyrrhonian scepticism. "I think," she says, "that Charron's De la sagesse is based primarily on Stoic, rather than Sceptic principles." Although I agree in general with the main thrust of Popkin's thesis, I too have been critical of his failure to give sufficient weight to the neo-Stoic dements of Charron's thought. Hence it is not this conclusion to which I take exception.2 Charron has, from the very beginning, been found to have said a great many things and been subjected to a wide variety of interpretations. Horowitz emphasizes "the seeds of virtue and knowledge [as] the dynamic center of De la sagesse"--a view which may appear perfectly plausible to some readers. But it can never compel widespread conviction, for the simple reason that it is impossible for a twentieth-century critic to enter--unaided--into a world of ideas now part of a remote past. A book written nearly four centuries ago is not immediately perspicuous. Before trying on our neo-idealist wings and taking flight into the empyrean of late Renaissance moral treatises, we would do well to explore as many as possible of the following questions: Just who was our author? For whom did he write? Who x p. Gay, Introduction to E. Cassirer, The Question of Jean-Jacques Rousseau (Bloomington, 1963), p. 22, cited by M. C. Horowitz, "Pierre Charron's View of the Source of Wisdom," Journal o! the History of Philosophy, IX, 4 (October, 1971), 457. 2 A. Soman, "Pierre Charron: A Revaluation," BibliothOque d'Humanisme et Renaissance, XXXII (January, 1970), 57 n. 3. [495] 496 HISTORY OF PHILOSOPHY in fact did read him? and how did his readers react? And what did our author think of their reactions.'?s Horowitz does not, apparently, give high priority to such questions. For rhetorical purposes, she readily agrees with Eugene Rice that "Pierre Charron's De la sagesse is the most important Renaissance treatise on wisdom." (Important to whom? and from what point of view? The criteria are not at all clear.) She assumes that Charron's epistemology was consistent, and that the second edition of 1604 represents a clarification of, or advance over, the first edition of 1601. (There is no historical evidence for making either assumption.) And she does not seem to entertain the possibility that Popkin could still be right about the impact of Charron's Pyrrhonian scepticism on the libertins Jrudits, although Charron may never in fact have been a Pyrrhonian sceptic.4 These are... (shrink)

What does it mean to ‘give’ the value of a variable in an algebraic context, and how does giving the value of a variable differ from merely describing it? I argue that to answer this question, we need to examine the role that giving the value of a variable plays in problem-solving practice. I argue that four different features are required for a statement to count as giving the value of a variable in the context of solving an elementary algebra (...) problem: the variable must be in the scope opened by the problem statement; the values given must be in the range of the variable, which is determined by the problem; the statement giving the values must represent a complete solution; and it must be in a canonical form. This account helps us better understand elementary algebra itself, as well as the use of algebraic tools to analyze phenomena in natural language. (shrink)

Sex chromosomes can differ between species as a result of evolutionary turnover, a process that can be driven by evolution of the sex determination pathway. Canonical models of sex chromosome turnover hypothesize that a new master sex determining gene causes an autosome to become a sex chromosome or an XY chromosome pair to switch to a ZW pair (or vice versa). Here, a novel paradigm for the evolution of sex determination and sex chromosomes is presented, in which there is an (...) evolutionary transition in the master sex determiner, but the X chromosome remains unchanged. There are three documented examples of the novel paradigm, and it is hypothesized that a similar process could happen in a ZW sex chromosome system. Three other taxa are also identified where the novel paradigm may have occurred, and how it could be distinguished from canonical trajectories in these and additional taxa is also described. (shrink)