Editor's suggested further reading in BioEssays: Fields and field cancerization: The preneoplastic origins of cancer Abstract.

Many philosophers of the last century thought all moral judgments can be expressed using a few basic concepts — what are today called ‘thin’ moral concepts such as ‘good,’ ‘bad,’ ‘right,’ and ‘wrong.’ This was the view, fi rst, of the non-naturalists whose work dominated the early part of the century, including Henry Sidgwick, G.E. Moore, W.D. Ross, and C.D. Broad. Some of them recognized only one basic concept, usually either ‘ought’ or ‘good’; others thought there were two. But they (...) all assumed that other moral concepts, including such ‘thick’ ones as the virtue-concepts ‘courageous’ and ‘kindly,’ can be reductively analyzed using one or more thin concepts and some more or less determinate.. (shrink)

Recent medical and bioethics literature shows a growing concern for practitioners’ emotional experience and the ethical environment in the workplace. Moral distress, in particular, is often said to result from the difficult decisions made and the troubling situations regularly encountered in health care contexts. It has been identified as a leading cause of professional dissatisfaction and burnout, which, in turn, contribute to inadequate attention and increased pain for patients. Given the natural desire to avoid these negative effects, it seems to (...) most authors that systematic efforts should be made to drastically reduce moral distress, if not altogether eliminate it from the lives of vulnerable practitioners. Such efforts, however, may be problematic, as moral distress is not adequately understood, nor is there agreement among the leading accounts regarding how to conceptualize the experience. With this article I make clear what a robust account of moral distress should be able to explain and how the most common notions in the existing literature leave significant explanatory gaps. I present several cases of interest and, with careful reflection upon their distinguishing features, I establish important desiderata for an explanatorily satisfying account. With these fundamental demands left unsatisfied by the leading accounts, we see the persisting need for a conception of moral distress that can capture and delimit the range of cases of interest. (shrink)

ABSTRACT A trivalent theory of indicative conditionals automatically enforces Stalnaker's thesis – the equation between probabilities of conditionals and conditional probabilities. This result holds because the trivalent semantics requires, for principled reasons, a modification of the ratio definition of conditional probability in order to accommodate the possibility of undefinedness. I explain how this modification is motivated and how it allows the trivalent semantics to avoid a number of well-known triviality results, in the process clarifying why these results hold for many (...) bivalent theories. In short, the slew of triviality results published in the last 40-odd years need not be viewed as an argument against Stalnaker's thesis: it can be construed instead as an argument for abandoning the bivalent requirement that indicative conditionals somehow be assigned a truth-value in worlds in which their antecedents are false. (shrink)

In slapstick comedy, the worst thing that could happen usually does: The person with a sore toe manages to stub it, sometimes twice. Such errors also arise in daily life, and research traces the tendency to do precisely the worst thing to ironic processes of mental control. These monitoring processes keep us watchful for errors of thought, speech, and action and enable us to avoid the worst thing in most situations, but they also increase the likelihood of such errors when (...) we attempt to exert control under mental load (stress, time pressure, or distraction). Ironic errors in attention and memory occur with identifiable brain activity and prompt recurrent unwanted thoughts; attraction to forbidden desires; expression of objectionable social prejudices; production of movement errors; and rebounds of negative experiences such as anxiety, pain, and depression. Such ironies can be overcome when effective control strategies are deployed and mental load is minimized. (shrink)

From Nietzsche's early writings to those marking the end of his intellectual life, the dynamics of what he called "physiology" permeate virtually every facet of his philosophical enterprise. In the following investigation, these dynamics are explored as an interpretive key to not only the dominant themes but also the philosophical motive underlying Nietzsche's philosophy. This motive is described in terms of his diagnosis and attempted cure for the disease of nihilism. In this we maintain that Nietzsche's foremost philosophical task is (...) that of a cultural physician. ;In pursuit of this theme, Nietzsche's "clinical standpoint" is explored and applied with regard to Socrates and Jesus Christ as two case studies in decadence. These two "cases" are a simultaneous physiological investigation into both the ancient Greek and Hebrew cultures. ;This investigation concludes with a detailed analysis of the physiological significance of the Revaluation of all Values, Eternal Recurrence, the Overman and Dionysus as integral to curing the sickness of nihilism. (shrink)

In her work Horrendous Evils and the Goodness of God, Marilyn McCord Adams offers an account of the problem of evil that deals with the interaction between certain types of evil and the human capacity for meaning production. This paper attempts to consider certain implications of her presuppositions and, in so doing, to uncover several challenges to her broader project entailed by said implications. More specifically, this paper considers, within the context of Adams’ broader project, the status of perpetrators of (...) horrendous evils with respect to their ability to conceive of said evils, evils that destroy meaning-making capacities in their victims and evils that twist and subvert the meaning-making processes of their victims or observers. (shrink)

If there are true contradictions, where are they? In language or in the world? According to one important view, best represented by Jc Beall (2009), only the former. In this paper, we raise a problem for this view. In order to defend a “merely semantic” version of dialetheism (aka ‘glut theory’), Beall adopts transparent accounts of truth and falsity, which gives rise to “dialethic ascent” on which true contradictions are also, contradictorily, untrue contradictions. This is a consequence of trying to (...) restrict contradictions to language and keep them out of the world. However, in this paper, we show that this ascent carries over intensional contexts, so that, on this version of dialetheism, even if there are true contradictions, no one knows a true contradiction. This shows that contradictions have not been kept out of the world. We end by connecting this issue with the infamous ‘just true’ problem. (shrink)

On a Dreyfusian account performers choke when they reflect upon and interfere with established routines of purely embodied expertise. This basic explanation of choking remains popular even today and apparently enjoys empirical support. Its driving insight can be understood through the lens of diverse philosophical visions of the embodied basis of expertise. These range from accounts of embodied cognition that are ultra conservative with respect to representational theories of cognition to those that are more radically embodied. This paper provides an (...) account of the acquisition of embodied expertise, and explanation of the choking effect, from the most radically enactive, embodied perspective, spelling out some of its practical implications and addressing some possible philosophical challenges. Specifically, we propose: an explanation of how skills can be acquired on the basis of ecological dynamics; and a non-linear pedagogy that takes into account how contentful representations might scaffold skill acquisition from a radically enactive perspective. (shrink)

Prescription opioid abuse (POA) is an escalating clinical and public health problem. Physician worries about iatrogenic addiction and whether patients are ‘drug seeking’, ‘abusing’ and ‘diverting’ prescription opioids exist against a backdrop of professional and legal consequences of prescribing that have created a climate of distrust in chronic pain management. One attempt to circumvent these worries is the use of opioid contracts that outline conditions patients must agree to in order to receive opioids. Opioid contracts have received some scholarly attention, (...) with trust and trustworthiness identified as key values and virtues. However, few articles have provided a critical account of trust and trustworthiness in this context, particularly when there exists disagreement about their role in terms of enhancing or detracting from the patient–physician relationship. This paper argues that opioid contracts represent a misleading appeal to patient–physician trust. Assuming the patient is untrustworthy may wrongfully undermine the credibility of the patient's testimony, which may exacerbate certain vulnerabilities of the person in pain. However, misplaced trust in certain patients may render the physician vulnerable to the potential harms of POA. If patients distrust their physician, or feel distrusted by them, this may destabilise the therapeutic relationship and compromise care. A process of epistemic humility may help cultivate mutual patient–physician trust. Epistemic humility is a collaborative effort between physicians and patients that recognises the role of patients’ subjective knowledge in enhancing physicians’ self-understanding of their theoretical and practice frameworks, values and assumptions about the motivations of certain patients who report chronic pain. (shrink)

John Stuart Mill regards economics as an inexact and separate science which employs a deductive method. This paper analyzes and restates Mill's views and considers whether they help one to understand philosophical peculiarities of contemporary microeconomic theory. The author concludes that it is philosophically enlightening to interpret microeconomics as an inexact and separate science, but that Mill's notion of a deductive method has only a little to contribute.

Sauquillo González, Julián. La reforma constitucional. Sujetos y límites del poder constituyente. Tecnos, Madrid, 2018, 406 páginas.

commentary on Fodor, “Against Darwinism.”.

The recent publication of the stenographer's transcript of Whitehead's guest lecture on “social ethics” has shed new light on the relation between his metaphysics and ethics. Instead of including ethics in his philosophy, Whitehead treats it as a distinct, specialized science that does not share in the universality of metaphysics. The present article argues that an analysis of his lecture shows that a nonindividualist Whiteheadian ethics is possible without rupturing the coherence of Whitehead's system or contradicting the ontological or subjectivist (...) principle. As part of a larger transition in Whitehead's thinking during the years 1925–1927, he reformulates the notion of the environment as inheritance and is therefore able to pose the question of the endurance of values at the level of society, which is the purview of ethics. Reconstructing the metaphysical background may provide a “stimulus to the imagination” for ethical debates today, especially in the field of environmental ethics. (shrink)

There is an underappreciated disconnect between the ultimate values that lie at the heart of contemporary theories of distributive justice, and the practice of state institutions. State institutions deliver “intermediate goods” – goods such as health-care, education, housing, transportation, and the like – that are instrumental to a society being distributively just, but that do not in an of themselves constitute criteria of justice. Researchers who have emphasized the “social determinants of health” provide an insight that, when generalized, point us (...) in a direction that theorists of distributive justice should follow, that of attending not just to the instrinsic value of intermediate goods, but also to their causal contributions to realizing the values that theories of distributive justice make central. “Platforms”, which represent principle-driven attempts at designing compossible policies that attend both to the causal and to the intrinsic value of intermediate goods, should be given more importance within theories of distributive justice if such theories are to be policy-relevant, for they connect the ultimate values of these theories to the practices of state institutions. (shrink)

John Dewey's classical pragmatism, Daniel M. Savage asserts, can be used to provide a self-development-based justification of liberal democracy that shows the current debate between liberal individualism and republican communitarianism to ...

Thought: A Journal of Philosophy, Volume 10, Issue 1, Page 42-52, March 2021.

Deleuze’s philosophy of immanence, because it vigorously rejects every appeal to the beyond, is often presumed to be indifferent to the concerns of religion. This book argues against such a presumption. It does so, first of all, by emphasising how both Deleuze’s thought and the notion of religion are motivated by a demand to create new modes of existence, or to imagine and enact a future that would substantively break with the present configuration of being. If Deleuze’s thought and the (...) notion of religion intersect in this regard, then their divergence must be located elsewhere, namely in the distinction between immanence and transcendence. The book thus argues that the enemy of Deleuze’s thought is not religion in general but instead the specific operation of transcendence. Furthermore, it argues that since Deleuze’s thought is not simply anti-religious, it cannot be identified with secularism. Along these lines, the book shows how Deleuzian immanence is able both to oppose religious transcendence and to enter an allliance with immanent accounts of the name of God. The effect of this is to suspend the paralysing debate between religion and the secular in order to attend to the ways in which immanence – whether “religious” or “secular” – is able to break with the present and to create the future. (shrink)

Sex differences in mortality rates stem from genetic, physiological, behavioral, and social causes that are best understood when integrated in an evolutionary life history framework. This paper investigates the Male-to-Female Mortality Ratio (M:F MR) from external and internal causes and across contexts to illustrate how sex differences shaped by sexual selection interact with the environment to yield a pattern with some consistency, but also with expected variations due to socioeconomic and other factors.

Adam Smith's lectures present a bleak theory of history in which the innate human results in the perpetuation of increasingly repressive slave societies. This theory challenges common conceptions about the philosophical and historical foundations of Smith's thought, and accounting for it requires moving beyond traditional dichotomies between an sphere grounded on asocial wants and a sphere grounded on sociability. For Smith, under the influence of earlier thinkers like La Rochefoucauld, Mandeville, and Rousseau, all human behavior is rooted in our esteem-seeking (...) social nature, and the dominant form of esteem-seeking is a one based on external superiority. Understanding these foundations explains why Smith views both European commercial society and its central motive of economic self-interest as historically contingent, the product of a long series of unintended historical consequences. (shrink)

Einstein’s razor, a corollary of Ockham’s razor, is often paraphrased as follows: make everything as simple as possible, but not simpler. This rule of thumb describes the challenge that designers of a legal system face—to craft simple laws that produce desired ends, but not to pursue simplicity so far as to undermine those ends. Complexity, simplicity’s inverse, taxes cognition and increases the likelihood of suboptimal decisions. In addition, unnecessary legal complexity can drive a misallocation of human capital toward comprehending and (...) complying with legal rules and away from other productive ends. While many scholars have offered descriptive accounts or theoretical models of legal complexity, most empirical research to date has been limited to simple measures of size, such as the number of pages in a bill. No extant research rigorously applies a meaningful model to real data. As a consequence, we have no reliable means to determine whether a new bill, regulation, order, or precedent substantially effects legal complexity. In this paper, we begin to address this need by developing a proposed empirical framework for measuring relative legal complexity. This framework is based on “knowledge acquisition”, an approach at the intersection of psychology and computer science, which can take into account the structure, language, and interdependence of law. We then demonstrate the descriptive value of this framework by applying it to the U.S. Code’s Titles, scoring and ranking them by their relative complexity. We measure various features of a title including its structural size, the net flow of its intra-title citations and its linguistic entropy. Our framework is flexible, intuitive, and transparent, and we offer this approach as a first step in developing a practical methodology for assessing legal complexity. (shrink)

Short epics in Middle High German are a challenge for author attribution procedures as they involve dealing with short texts, incomplete normalisation, and generic tests. Firstly, the paper discusses optimisation methods using basic form and grammar tags extracted from the ‘Mittelhochdeutsche Begriffsdatenbank’ (Middle High German Conceptual Database). As part of this, an evaluation test with normalised Middle High German texts is carried out where 20 texts with known authorship are used as ‘guessing texts’ and a further 19 works of the (...) same authors as ‘comparison texts’. The use of grammar tags or basic forms, instead of inflected word forms leads to a deterioration of the recognition rate and the combination of basic forms or grammar tags with word forms leads to a slight improvement. Secondly, the authorship of the ‘Halbe Birne’ will be investigated with eight texts by Konrad von Würzburg, as well as a comparative corpus of 14 tales (German ‘Mären’) and seven novels. This leads to a direct calculation of which words can be specifically ascribed to Konrad von Würzburg. This method is first evaluated by determining the distinctive words on four Konrad texts; a control test on four other Konrad texts shows that a preferred use of the distinctive words leads to a significant increase in the recognition rate. Then, a Konrad-specific vocabulary is determined on the basis of eight Konrad texts. Using these distinctive words it can finally be shown that Konrad can be attributed with some certainty as the author of the ‘Halbe Birne’. (shrink)

It is common to think that certain acts are supererogatory, especially certain heroic or saintly self-sacrifices for the good. The idea seems to have an ordinary and clear application. Nothing shows this better than the well-known cases which J. O. Urmson adduced. Urmson argued that no major moral theory could give a proper account of the supererogatory character of such acts, and that therefore none could account for “all the facts of morality,” as he put it. But his arguments were (...) sketchy. This paper shall show, in some detail, that he was essentially right about Kant’s moral theory, and that the criticism goes deep and holds up against recent sympathetic interpretation of Kant’s views of duty and worth. (shrink)

El sustantivo πραπίς / πραπίδες presenta diversos usos en los poemas homéricos, de acuerdo con diferentes campos semánticos que van desde lo anatómico a lo cognoscitivo. Desde la Antigüedad se intentó clarificar el sentido básico del término, equiparándolo con los distintos campos semánticos que comprende el sustantivo φρήν / φρένες. El término no aparece nunca en singular en los poemas homéricos sino siempre en plural.. Este trabajo pretende clarificar, en general, la significación del término y, en particular, el sentido que (...) adquiere cuando es empleado en singular, apelando tanto al recurso de reconstrucción de una hipotética raíz indoeuropea como a conceptos de la teoría cognitiva-prototípica como los de conceptualización, metonimización, metaforización y modelización. The word πραπίς / πραπίδες has diverse uses in the Homeric poems according to different semantic fields going from the anatomical to the cognitive. Since antiquity it has been tried to explain the proper sense of the term comparing it with the diverse semantic fields that present the word φρήν / φρένες. The term does never appear in its singular form in the Homeric poems but always in its plural form. The purpose of this work is to explain the meaning of the term in general, and in particular, the sense of the term in singular number, appealing both to device of a hypothetical reconstruction of Indo-European root as notions of the cognitive-prototype theory such as conceptualization, metonymization, metaphorization and modeling. (shrink)