BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Contrairement à la majorité des interprètes du Timée de Platon, nous ne croyons pas que la figure du démiurge représente réellement une cause productrice. Ce type de causalité, explicitement attribué au νοῦς dans le Phédon, ne peut, selon nous, être associé qu’à l’activité de l’âme du monde et des dieux de la tradition. Le démiurge joue un autre rôle. Représentant le meilleur des êtres intelligibles éternels (37a), un dieu éternel (34a), le démiurge ne peut, à ce titre, être un principe (...) de mouvement, puisque l’intelligible, selon Platon, n’exerce qu’une causalité paradigmatique. La figure du démiurge est, en fait, la représentation mythique de la causalité paradigmatique. Le démiurge représente, plus précisément, à titre de « fabricant » de l’espèce des dieux, la forme intelligible du dieu. Certaines caractéristiques du démiurge (sa corporéité, ses pensées et son activité productrice) sont indissociables de l’analogie employée pour représenter la dépendance des dieux à l’égard des formes intelligibles : le travail artisanal. Le démiurge, en tant que cause productrice, n’a pas de valeur ontologique réelle. Néanmoins, ce qu’il représente, la forme intelligible du dieu, constitue, selon Platon, la cause qui fonde l’immortalité de l’univers et des dieux de la tradition, une cause qui permet ainsi au νοῦς de ces divinités d’exercer leur causalité productrice. (shrink)

Résumé : Les représentations sociales font l’objet d’études en sciences humaines et sociales depuis plus de cinquante ans. En fonction de la théorie du noyau central, la représentation sociale peut être définie en tant qu’organisation structurée et hiérarchisée selon deux systèmes : un central et un périphérique. Au fil du temps et à partir du discours des répondants, des travaux réalisés par des chercheurs de l’Université de Sherbrooke ont permis, par l’entremise du recours à l’analyse lexicométrique et à la statistique (...) textuelle, d’identifier des éléments du noyau central ainsi que des éléments périphériques dans les différentes recherches. Cette contribution vise à mettre en perspective nos orientations méthodologiques, à revenir sur la nécessité de recourir à des approches pluriméthodologiques et à proposer des modèles alternatifs pour les échantillons plus faibles. -/- Abstract : Social representations have been the subject of study and analysis in social sciences and humanities for over fifty years. According to the central nucleus theory, social representation can be defined as a structured and a hierarchical organization according to two systems: one central, and one peripheral. By analyzing participants answers, several different studies have been previously published by researchers from the University of Sherbrooke. These studies have identified central core elements as well as peripheral elements by using lexicometrical analysis and textual statistics. This contribution aims to put into perspective our methodological orientations as well as to reconsider the need to use pluri-methodological approaches and to propose alternative models for small samples. (shrink)

Recent research has revealed the widespread effects of emotion on cognitive functions and memory. However, the influence of emotional valence on verbal short-term memory remains largely unexplored, especially in children. This study measured the effect of emotional valence on word immediate serial recall in 4–6-year-old French children (N = 124). Results show a robust effect of emotional valence on recall performances and recall errors. More precisely, we observed a facilitating effect of the positive valence of words: it allows better performance (...) and causes few recall errors. On the contrary, the data indicated a disruptive impact of negative word valence: the latter causes very low recall performance and is associated with a high proportion of recall errors. These findings add new evidence of the influence of emotion on children’s verbal short-term memory. Our results are discussed in relation to current semantic and attentional explanations of the emotional enhancement of memory. (shrink)

Durkheim écrit ce livre avec un but double : d'abord il voulait expliquer ce qui crée une société, ce qui la tient ensemble ; ensuite il voulait éclaircir l'influence qu'a la société sur la pensée logique. Pour Durkheim, la religion est la clé utilisée pour déverrouiller ces deux problématiques.Dans ce livre, Durkheim argumente que les représentations religieuses sont en fait des représentations collectives : l'essence du religieux ne peut être que le sacré. Il est une caractéristique qui se trouve universellement (...) dans toutes les religions. Le sacré, être collectif et impersonnel, représente ainsi la société elle-même. Ensuite il argumente que la société a un impact majeur dans la genèse de la pensée logique. C'est la société qui fournit à l'individu les catégories (le temps, l'espace, le nombre etc.) et les concepts nécessaires pour la pensée logique. (shrink)

É bem conhecida a oposição estabelecida por Kant entre experiência possível e dialética, na medida em que esta última é caracterizada como a “lógica da ilusão”. Ao mesmo tempo, o modo de pensar metafísico, que ocorre dialeticamente, em sentido kantiano, é uma tendência inevitável da razão, expressa na exigência formal de completude das categorias. Como o pensar, enquanto exercício livre da razão, é em si mesmo mais amplo do que a atividade de conhecer, própria do entendimento, o pensar contém o (...) conhecimento, embora este se qualifique pelas regras e pelos limites determinantes da objetividade. A pergunta que tentaremos formular é se essa relação continente-conteúdo não poderia configurar também uma dependência da experiência em relação ao raciocínio dialético, que estaria de algum modo indicada na função reguladora das idéias da razão. Nesse caso, a oposição formal entre conhecer e pensar seria inseparável da inclusão estrutural (dependência) da experiência no âmbito da razão. Na raiz do problema estaria talvez a tensão (dialética) entre a aspiração subjetiva de totalidade e as exigências objetivas de limitação e segmentação da experiência e a forma da experiência teria de ser finalmente concebida a partir de um fundo de inteligibilidade problemática. Dialectics and experienceThe separation of possible experience as objective knowledge and dialetics as a non-objective or non-theoretical knowledge is one of the most important aspects of kantian critical philosophy. But Kant also says that the activity of reason, as a pure thinking, has more amplitude than understanding knowledge. So we could say that theoric knowledge would depend on rational ( and non-theoretical) knowledge, as something contained in it. If we accept that, the consequence would be a relation of dependence between the form of objective knowledge and the background of a problematic – even doubtful – inteligible knowledge. (shrink)

gl. 1. Ėkofilosofii︠a︡ kak zhiznesokhrani︠a︡i︠u︡shchiĭ kulʹturnyĭ proekt -- gl. 2. Obrazy kulʹtury mira v istoriko-personologicheskom izmerenii -- gl. 3. Borʹba za mir v sovremennom mire : opyt, kont︠s︡ept︠s︡ii, modeli resheniĭ.

Em artigo inédito, Franklin Leopoldo e Silva desenvolve os sentidos da memória na produção da identidade, destacando as relações significativas do presente com o passado e o futuro na construção da história. Desse ponto, o autor acentua o papel das instituições nesse processo – um processo de exercício de poder, no qual se tem, na verdade, a institucionalização do poder – e, dentre elas, em particular a instituição universitária.

O presente artigo visa analisar, a partir do pensamento do filósofo Michel Foucault, o exercício da liberdade sob uma perspectiva ética, no âmbito do estoicismo tardio. Liberdade essa que se faz possível a partir do cuidado de si, por meio de exercícios regulares que possibilitam ao indivíduo viver a vida como arte. Com efeito, é na prática do cuidado de si, que o indivíduo se coloca como transformador do mundo e de si mesmo, o qual dá-se no encontro com o (...) outro, longe de ser uma experiência solitária com o próprio eu, realiza-se na associação com outrem. (shrink)

Neste livro Gombrich discute as idéias e as posturas específicas que tiveram influência decisiva na prática da arte renascentista. Todos os estudos aqui reunidos tratam de algo a que se pode chamar clima renascentista de opiniões sobre a arte, além da influência desse clima sobre a prática e a crítica da arte.

Alfred Edward Housman (1859–1936), ki je kasneje postal angleški pesnik in eden največjih filologov svojega časa, je svoj zafrkantski »fragment« objavil pri triindvajsetih, leta 1883, v reviji Bromsgrovian. Revijo je izdajala Bromsgrove School, kjer se je šolal kot najstnik (1870–77); na šolo, ki je prva prepoznala njegov jezikovni in pesniški talent, se je za kratek čas (1881–82) vrnil kot pomožni učitelj po ne­pričakovanem študijskem porazu na Oxfordu. Kot ugotavlja Ralph Marcellino, ni naključje, da besedilo paro­dira predvsem Ajshila, ki je bil (...) Housmanov najljubši pesnik. V njem odzvanja Oresteja, zlasti drami Agamemnon in Prinašalke pitnih darov, verjetno zato, ker so ju dijaki na šoli, kjer je poučeval, pri pouku največ brali. Prav ta ciljna publika je znala ceniti norčevanje iz retoričnih figur ter sintaktičnih konstrukcij, ki jim jih je njihov pomožni učitelj vbijal v glavo. (shrink)

Wittgenstein’s concepts shed light on the phenomenon of schizophrenia in at least three different ways: with a view to empathy, scientific explanation, or philosophical clarification. I consider two different “positive” wittgensteinian accounts―Campbell’s idea that delusions involve a mechanism of which different framework propositions are parts, Sass’ proposal that the schizophrenic patient can be described as a solipsist, and a Rhodes’ and Gipp’s account, where epistemic aspects of schizophrenia are explained as failures in the ordinary background of certainties. I argue that (...) none of them amounts to empathic-phenomenological understanding, but they provide examples of how philosophical concepts can contribute to scientific explanation, and to philosophical clarification respectively. (shrink)

Los recientes desarrollos de la inteligencia artificial generativa suponen desafíos a conceptos tradicionales del Derecho, uno de ellos es el de autoría. El problema que aborda este trabajo es cómo concebir la autoría de una obra escrita por una inteligencia artificial generativa en la que la intervención humana, en cuestiones de estilo y contenido, es nula o mínima. Para ello se enumeran casos recientes en los que se plantea ese problema a partir de artículos escritos empleando ese tipo de tecnología. (...) Pero el objetivo del trabajo es la revisión de la concepción de autoría que subyace a las normativas internacionales que regulan la propiedad intelectual y los presupuestos éticos que las justifican (la concepción de Locke, la concepción romántica y la concepción utilitarista). Sobre la base de una lectura de “¿Qué es un autor?” de Michel Foucault se sostiene que la noción de autoría cumple una función social que, al menos al estado del arte de la inteligencia artificial generativa, esta no puede cumplir y, por tanto, no debe ser reconocida como autora de las obras mencionadas. Concluyendo que las obras literarias elaboradas por inteligencia artificial generativa multipropósito con nula o escasa intervención humana deben ser consideradas como obras de dominio público. (shrink)

O objetivo deste texto é explorar aproximações e divergências no pensamento de Paulo Freire e Ivan Illich na forma como eles vêem a relação entre educação e transformação social. Acredita-se que a retomada da polêmica Freire e Illich sobre o problema educação e transformação social pode contribuir para melhor compreender e esclarecer a verdadeira natureza desse problema, já clássico na história da educação moderna.

Great advances have been made of late years in the understanding of ancient artillery, but the difference between the παλíντινιν and the εθτινιν seems to remain a riddle still inviting solution. In tentatively accepting the invitation, we are met at the outset by a certain amount of fog due to the fact that ancient guns were classed by two methods which produce a cross division. It will pay us to dispel this fog, or at any rate to find our bearings (...) in it as exactly as may be, before going further. (shrink)