Née des craintes, voire des frayeurs, générées par le développement de la science, la bioéthique a conduit les chercheurs, spécialisés dans l'étude du vivant, à s'interroger sur les dangers que leur discipline peut engendrer : le progrès scientifique est-il toujours souhaitable? Ne risque-t-il pas de mener à des innovations et à des avancées, intellectuellement stimulantes certes, mais éthiquement inacceptables? Tel est le sujet de cet ouvrage collectif.

The historically most central epistemological issue concerning perception, to which this article will be almost entirely devoted, is whether and how beliefs about physical objects and about the physical world generally can be justified or warranted on the basis of sensory or perceptual experience—where it is internalist justification, roughly having a reason to think that the belief in question is true, that is mainly in question (see the entry justification, epistemic: internalist vs. externalist conceptions of). This issue, commonly referred to (...) as “the problem of the external world,” divides into two closely related sub-issues, which correspond to the first two main sections below. The first of these issues has to do with the nature of sensory experience and its relation to the physical world; it is typically (though as we shall see not altogether perspicuously) formulated as the question of what are the immediate objects of awareness in sensory experience or, in a variant but essentially equivalent terminology, of what is given in such experience. Perhaps the most historically standard, though not currently the most popular answer to this question has been that it is sense-data (private, non-physical entities that actually have the immediately experienced sensory qualities) that are the immediate objects of awareness or that are given. The second issue has to do with the way in which beliefs about the physical world are justified on the basis of such sensory experience. If it is concluded that physical objects are not themselves given, the two main answers to this question are representationalism or indirect realism (the view that the immediate objects of experience represent or depict physical objects in a way that allows one to infer justifiably from such experience to the existence of the corresponding “external” objects) and phenomenalism (the view.. (shrink)

Technology used in online marketing has advanced to a state where collection, enhancement and aggregation of information are instantaneous. This proliferation of customer information focused technology brings with it a host of issues surrounding customer privacy. This article makes two key contributions to the debate concerning digital privacy. First, we use theories of justice to help understand the way consumers conceive of, and react to, privacy concerns. Specifically, it is argued that an important component of consumers' privacy concerns relates to (...) fairness judgments, which in turn comprise of the two primary components of distributive and procedural justice. Second, we make a number of prescriptions, aimed at both firms and regulators, based on the notion that consumers respond to perceived privacy violations in much the same way they would respond to an unfair exchange. (shrink)

Leibniz's earliest philosophy and its importance for his mature philosophy have not been examined in detail, particularly in the level of detail that one can achieve by placing Leibniz's philosophy in the context of the sources for two of the most basic concerns of his philosophical career: his metaphysics of individuals and the principle oftheir individuation. In this book I provide for the first time a detailed examination of these two Leibnizian themes and trace its implications for how we should (...) interpret other major Leibnizian themes and for how we should read Leibniz and other philosophers of the sixteenth and later centuries as 'modem' philosophers. Leibniz began his philosophical career more than 300 years ago, a fact that shapes fundamentally my attempt in the pages that follow to come to terms now with the texts that he left us. Leibniz's did not do philosophy in a way wholly congenial to twentieth century philosophical methodologies, especially those that have enjoyed some prominence in recent Anglo-American philosophy. Moreover, as we shall see, Leibniz is not a modem philosopher, when 'modem' is understood to mean making a sharp break with medieval philosophy. Indeed, I shall argue, scholars should discard such terms as 'modem' from historical philosophical scholarship, so that old texts can be allowed to remain old - to stand on their own in and from times now long past. (shrink)

A commentary on “The Ethics of Anonymous Gamete Donation: Is There a Right to Know One's Genetic Origins?” by Inmaculada de Melo‐Martín, in the March‐April 2014 issue.

(2001). The History of Medical Ethics Is Crucial for a Critical Perspective in the Continuing Development of Ethics Consultation. The American Journal of Bioethics: Vol. 1, No. 4, pp. 55-57.

Despite their common core in statistics, insurance and epidemiology propel two different forms of solidarity. In insurance, the collective is a source of protection, thanks to the pooling of risks; in epidemics by contrast, the group remains the source of danger for the individual. The aim of this paper is to highlight the conceptions of community and solidarity at play in epidemics in contradistinction to insurance, with a focus on the shift introduced by big data and algorithms. Paradoxically, while the (...) new technologies and epidemiology share a common view on the relation between the individual and the collective, tracing apps were not widely adopted in the Covid-19 crisis. This reluctance to use current technologies for the sake of epidemic containments highlights, beyond legitimate interrogations, a confusion between two imaginaries of the social: insurance solidarity where the interdependence is a source of rights, and epidemic solidarity that imposes duties. (shrink)

This study investigated the mechanisms behind episodic autobiographical memory development in school-age children. Thirty children performed a novel EAM test. We computed one index of episodicity via autonoetic consciousness and two indices of retrieval spontaneity for a recent period and a more remote one . Executive functions, and episodic and personal semantic memory were assessed. Results showed that recent autobiographical memories were mainly episodic, unlike remote ones. An age-related increase in the indices of episodicity and specific spontaneity for recent AMs (...) was mainly mediated by an age-related increase in the efficiency of the three cognitive abilities. Remote AMs varied only slightly with age , reflecting improvements in semantic abilities. Thus, EAM development in school-age children is essentially bound up with the increasing efficiency of cognitive abilities. Results are discussed in the light of models of childhood amnesia. (shrink)

Boyle prefaced his Disquisition about the Final Causes of Natural Things with the claim that there are three dangerous consequences for failing to engage in the pursuit of final causes. Boyle was sincere in this claim, for there is a systematic line of reasoning in his texts that incorporates all three consequences and establishes conceptual connections between his science, his theology, and his value theory. I argue in this paper that Boyle's teleological outlook led him to believe that the natural (...) philosopher is morally obligated to continue his investigations of nature on the grounds that a deeper understanding of the teleological order necessarily motivates divine worship. Moreover, Boyle saw a conceptual connection between a teleological study of nature and revealed theology, a connection that reveals that a study of teleological nature can lead to the highest form of happiness. I conclude with a summary, and some remarks about the sincerity and weaknesses of Boyle's reasoning. (shrink)

Throughout his early writings, Leibniz was concerned with developing an acceptable account of God's relationship to the created world. In some of these early writings, he endorsed the idea that this relationship was similar to the human soul's relationship to the body. Though he eventually came to reject this idea, theanima mundi thesis remained the topic of several essays and correspondences during his career, culminating in the correspondence with Clarke. At first glance,Leibniz's discussions of this thesis may seem less important (...) in comparison to others, since it might seem like a topic which is far removed from what are regarded as his most important philosophical doctrines. I hope to show in what follows that such a view is mistaken. The large amount of attention Leibniz paid to this thesis is a sure indication of its importance to him. Further, as we shall see, his discussions of this thesis tum on some of his most interesting metaphysical topics, including the development of his thinking about the actual infinite, the structure of organic wholes, and the relationship between God and the created universe. In what follows, I examine these discussions chronologically, from the De Summa Rerum (1675-6), to the correspondence with Clarke (1715-6). (shrink)

In 2013, there were an estimated 50,000 individuals involved in downloading and sharing indecent images of children in the United Kingdom. This poses challenges for limited police resources. We argue that police officers can make most effective use of limited resources by prioritizing those offenders who pose the greatest risk of contact offending, by nature of demonstrable pedophilia, hebephilia or dual offending status and thus, those at highest risk must be dealt with first. What is currently lacking is a clear (...) idea of the potential scale of the problem in socio-economic terms and why, therefore, it is so important that evidence-based approaches to offender detection and investigation continue to be a top priority for funders and policy makers. A systematic literature review was undertaken to address two related questions. First, what is the scale of the problem in the UK, in terms of the number of pedophilic and hebephilic individuals who pose a risk of contact offending against a child? Second, what is the potential socio-economic burden generated by the national IIOC suspect pool if left unattended to by targeted police action? Applying population estimates of pedophilia and hebephilia to the male population, we estimate there are between 2,365–5,991 males with paedophila and 12,218–30,952 males with hebephilia who are likely contact offenders. Applying average prevalence and incidence based costing methods to a conservative estimate of one victim per offender, the combined socio-economic burden from these persons could amount to £236-£597 million increasing to £2.9-£7.3 billion. Applying the same costs to CEOP estimate of 50,000 IIOC offenders we estimate that between 6,000 and 27,500 dual offenders could have already committed past contact offenses, contributing an economic burden of between £97–£445 million increasing to £1.2–£5.4 billion. Future contact offenses could contribute a further burden of £16–£18.6 million increasing to £198–£227 million. Drawing upon these findings, we argue for the benefits of a research-informed prioritization approach to target IIOC offenders. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bioethics in the Twenty-First Century: Why We Should Pay Attention to Eighteenth-Century Medical EthicsLaurence B. McCullough (bio)Those of us who work in the field of bioethics tend to think that, because the word “bioethics” is new, so too the field is new in all respects, but we are not the first to do bioethics. John Gregory (1724–1773) did bioethics just as we do it, at least two centuries before (...) we thought to do it (Gregory 1772). He deployed philosophical methods as sophisticated as our own. Indeed, Gregory took up the very best moral philosophy available to thinkers of the Scottish Enlightenment, namely, David Hume’s moral philosophy and its core concept of sympathy. Gregory also responded in a conceptually powerful and clinically applicable way to the problems of his time, just as we do. I want here to outline Gregory’s accomplishment and to identify some aspects of its importance for bioethics in the twenty-first century.Gregory’s “Problem List”Gregory wrote his medical ethics as a response to the then current state of medicine in Britain. We now follow Gregory in our writing of bioethics and clinical ethics in response to the problems of our time. A great deal that we now take for granted did not then exist. 1There was not, as there is now, any uniform pathway into medicine. Nor did there exist universal licensure. The Royal Colleges did attempt to assert, but failed to achieve, monopoly control of medical practice. The concepts of health and disease were themselves contested and therefore competed for their success in the market place. There was a marked oversupply of practitioners who competed fiercely—very fiercely indeed—in the medical market place for their concepts of health and disease, their treatments, and therefore their livelihoods. Patients had their own concepts of health and disease, engaged in “self-physicking” or self-care, and often traded physician’s prescriptions.Medicine exhibited little scientific discipline in its accounts of disease and in determining the efficacy of treatments, a fact that Gregory (1743) laments as a [End Page 329] medical student. There was no marked improvement when he began to give his medical ethics lectures nearly a quarter of a century later. Treatments failed as often, perhaps more often, than they succeeded in benefiting patients. The sick usually sought out the help of a physician after trying self-physicking.Physicians, Gregory taught, could not hope to control human biology, though they could aim to manage its processes well. When nature underresponds to disease the physician should assist her processes; when nature overresponds, the physician should tamp down nature’s responses, to lessen their “violence”—in both cases always attentive to the limits of medicine’s capacities in treating disease.Physicians attended the well-to-do sick at home, and the sick person summoned and dismissed physicians, surgeons, or apothecaries at will. A physician therefore might find himself—no women had yet been admitted to the ranks of university-trained physicians—summoned before, after, or simultaneously with a competitor, with his concepts and diagnosis and treatment put to the acid test. In this setting, there existed only a patient-physician relationship, not a physician-patient relationship.Physicians left off the care of dying patients, a practice that was made a matter of duty by Friederich Hoffmann (1749). One would suffer punishing economic consequences if one had a high mortality rate. Better, then, to label the patient incurable, withdraw, and turn matters over to clergy. Gregory attacks this practice as intellectual fraud and calls for the physician to continue to attend the dying. Indeed, he says, “It is as much the business of a physician to alleviate pain, and to smooth the avenues of death, when unavoidable, as to cure diseases” (Gregory 1772, p. 35). He does not explicitly address what we now call physician-assisted suicide; neither does he condemn it, and he is quick to condemn some things—e.g., sexual abuse of female patients or “sporting” with patients in the Royal Infirmary by using experiments as the first line of treatment.The Royal Infirmary was established to care for the deserving, working poor, who received free care... (shrink)

Clinical ethics, like bioethics more generally, until recently has tended to focus on the present and future, with little attention to the history of moral thought about health care that preceded bioethics. As a consequence, clinical ethics and bioethics lack maturity as fields of the humanities. The papers in this year's clinical ethics issue of the Journal put contemporary clinical ethics in critical dialogue with the past, making the former accountable to the latter. The six papers in this issue of (...) the Journal are briefly described, with an emphasis on how they contribute to the maturation of clinical ethics as a field of the humanities. (shrink)

The American Journal of Bioethics, Volume 11, Issue 10, Page 34-35, October 2011.

The five papers in the 2008 “Clinical Ethics” number of the journal address the conceptual and empirical foundations of clinical ethics. Three articles take up the concept of professionalism in medicine, exploring its possibilities and implications. The fourth article provides a distinctive, phenomenological account of the “placebo effect,” a vexing topic of surprising durability in the clinical setting. The final article, a systematic review of the qualitative literature on bedside rationing of resources, creates an empirical foundation for philosophical analysis and (...) argument of a distinctive kind. (shrink)

In this paper, I address the topic of free will in Leibniz with particular attention to Leibniz's concept of volition, and its analogue in his physics – his concept of force. I argue against recent commentators that Leibniz was a causal determinist, and thus a compatibilist, and I suggest that logical consistency required him to adopt compatibilism given some of the concepts at work in his physics. I conclude by pointing out that the pressures to adopt causal determinism in Leibniz's (...) system are perhaps more severe than those facing the contemporary libertarian, pressures that stem from empirical considerations about the behavior of bodies in the physical world, and the “well‐founding” of those bodies in simple substances. (shrink)

Fluid-phase endocytosis (pinocytosis) kinetics were studied inDictyostelium discoideum amoebae from the axenic strain Ax-2 that exhibits high rates of fluid-phase endocytosis when cultured in liquid nutrient media. Fluorescein-labelled dextran (FITC-dextran) was used as a marker in continuous uptake- and in pulse-chase exocytosis experiments. In the latter case, efflux of the marker was monitored on cells loaded for short periods of time and resuspended in marker-free medium. A multicompartmental model was developed which describes satisfactorily fluid-phase endocytosis kinetics. In particular, it accounts (...) correctly for the extended latency period before exocytosis in pulse-chase experiments and it suggests the existence of some sorts of maturation stages in the pathway. (shrink)

The distinction usually made between Western and non-Western philosophy is one that disguises a more relevant and informative distinction: that between non-modern and modern forms of philosophy. In this article, I argue for taking the latter distinction as primary. The main reason for doing so is that it relates more intimately to the actual contents and methodologies of the philosophies being distinguished. In particular, the philosophies of Plato and Aristotle have more in common with those of precolonial (i.e. non-modern) Africa (...) than they do with those of modern Europe. I argue this through the close analysis of a few central examples. Further, I show how the distinction between the non-modern and the modern, as well as our appreciation of it, both strengthens and is strengthened by an understanding of Plato’s praise for the life of inquiry as the best life for a human being. (shrink)

In this paper, I will discuss three arguments which have been advanced by three of the most important recent analytic philosophers: Willard Van Orman Quine, Hilary Putnam, and Michael Dummett. Each argument is central to the views of the philosopher in question, and each leads to sweeping and, to my mind, highly implausible conclusions concerning the content of our thoughts about the world. The philosophers in question claim, of course, that these implications should be accepted, but few others have been (...) willing to follow them in this. At the same time, however, there has been no very widespread agreement on where and how the arguments go wrong. My view is that they are best viewed as reductions to absurdity of their premises and of one underlying premise in particular. [1] But just which premise is at fault is not, perhaps, immediately obvious. I will have more to say about that after we have had an initial look at the arguments. (shrink)

I argue that while Fumerton’s criticisms of pure coherence theories of truth are both important and extremely cogent, their application both to the main historical views usually identified as coherence theories of truth, viz. the views of the absolute idealists, and to contemporary anti-realism is more problematic. In addition, while Fumerton is again undeniably correct in his objection to pure coherence theories of justification, an impure coherence theory of justification may still be defensible.

En suspendant la violence de ses passions et de ses désirs, l'homme se montre capable d'une relation harmonieuse et respectueuse avec lui-même, les êtres et les choses, dans un dialogue avec la douceur de la vérité et la beauté de l'art qui la recrée. On étudiera comment, à l'âge humaniste et classique, les modernes ont pensé la douceur à partir de la relecture des sources antiques et chrétiennes dans les divers champs du savoir de la poétique à l'éthique, de la (...) métaphysique à l'esthétique et dessiné un idéal difficilement définissable et aisément rompu."--Page 4 of cover. (shrink)

_From the Eye of the Storm: Regional Conflicts and the Philosophy of Peace_ presents to the reader a cross section of an emerging field of study: the philosophy of peace. The editors bring together articles that explore the philosophic implications of many recent regional conflicts. Reflecting the diversity and vitality and any new field of study, this volume contains five sections: Conceptual Foundations; America's Homefront; Desert Storm Assessments; _Jihad, Intifada_, and Other Mideast Concerns; and Latin American Issues. The topics of (...) the articles include war, militarism, patriotism, nationalism, nonviolence, conscientious objection, feminist peace, the media, the ethics of the Gulf War, the Israeli-Palestinian conflict, Islamic pacifism, and Latin American resistance. A concluding postscript assesses prospects for achieving peace and change within our fast changing international scene. This volume has an extensive bibliography of writings concerning peace and conflict and is suited to professional and student audiences. (shrink)

Comment concilier le relatif et l’universel? C’est à cette délicate tâche que s’était attelée il y a déjà quelques années Madame Delmas-Marty, spécialement dans le domaine des droits de l’homme. Le présent ouvrage envisage une difficulté supplémentaire en croisant les interrogations sur le pluralisme juridique avec la question de l’effectivité du droit économique. La prise en compte des pluralismes, notamment du pluralisme juridique, contribue-t-elle à une meilleure effectivité du droit économique? Ou bien, au contraire, le pluralisme juridique est-il un facteur (...) d’ineffectivité du droit économique? Dans cette recherche, les auteurs se sont attachés au pluralisme aussi bien dans la production du droit économique que dans le règlement des différends. C’est ainsi que le lecteur est appelé à cheminer dans la diversité des formes nouvelles qu’empruntent les régulations juridiques pour partir à la recherche des multiples intérêts que peut prendre en charge le droit économique, qu’ils soient individuels, collectifs ou même futurs. Le voyage se poursuit, là encore dans les mondes aussi bien des formes que de la substance. L'ouvrage, après avoir cherché à cerner la notion d’effectivité au regard de notions voisines comme l’efficacité ou l’efficience, s’interroge in fine sur l’éventualité des voies d’un dépassement de la notion de pluralisme juridique. (shrink)