BackgroundPatient skepticism concerning medical innovations can have major consequences for current public health and may threaten future progress, which greatly relies on clinical research.The primary objective of this study is to determine the variables associated with patient acceptation or refusal to participate in clinical research. Specifically, we sought to evaluate if distrust in pharmaceutical companies and associated psychosocial factors could represent a recruitment bias in clinical trials and thus threaten the applicability of their results.MethodsThis prospective, multicenter survey consisted in the (...) administration of a self-questionnaire to patients during a pulmonology consultation. The 1025 questionnaires distributed collected demographics, socio-professional and basic health literacy characteristics. Patients were asked to rank their level of trust for pharmaceutical companies and indicate their willingness to participate in different categories of research.Logistic regression was used to determine factors contributing to “trust” versus “distrust” group membership and willingness to participate in each category of research.ResultsOne thousand patients completed the survey, corresponding to a response rate of 97.5%. Data from 838 patients were analyzed in this study.48.3% of respondents declared that they trusted pharmaceutical companies, while 35.5% declared distrust. Being female, inactive in the employment market, and not-knowing the name of one’s disease are factors related to declared distrust. Distrust-group membership is associated with unwillingness to participate in certain categories of trials such as pre-marketing and industry-sponsored trials.ConclusionDistrust in pharmaceutical companies is associated with a specific patient profile and with refusal to participate in certain subcategories of trials. This potential recruitment bias may explain the under-representation of certain categories of patients such as women in pre-marketing drug trials. (shrink)

Perú es indiscutiblemente un país multilingüe, con 48 lenguas habladas en diferentes grados de uso y dominio. En Ayacucho, uno de los departamentos de Perú, se hablan tanto el quechua como el español, lo que resulta en un alto grado de bilingüismo en la población. El objetivo de este estudio fue analizar la estrategia de la gramática contrastiva quechua-castellano en los niveles fonológicos, morfológicos, sintácticos y semánticos en la población de Ayacucho. Para ello, se adoptó un enfoque cualitativo y se (...) utilizaron técnicas de entrevista y revisión documental. Los resultados indican que la gramática contrastiva entre el quechua y el castellano a nivel fonológico, morfológico, sintáctico y semántico es altamente efectiva para el aprendizaje tanto de la primera como de la segunda lengua. (shrink)

Les espaces de rencontre enfants/parents (ou erep ) sont des lieux dédiés aux rencontres d’un parent et de son ou ses enfants, dans un contexte de conflit conjugal rendant impossible l’exercice de droits de visite classiques. Ils peuvent être la scène de vécus difficiles pour les enfants concernés. Cet article propose, à travers le récit détaillé puis une lecture interprétative d’une vignette clinique concernant un enfant de 6 ans venant rencontrer son père en erep, la mise en évidence, à l’aide (...) d’outils théoriques issus de la littérature psychanalytique, des conséquences négatives du clivage des discours parentaux sur le travail d’élaboration identitaire de l’enfant, en lien avec sa filiation. Il est également question du rôle actif que peuvent jouer les professionnels de l’espace de rencontre dans la réduction de tels clivages, défendant ainsi l’intérêt supérieur de l’enfant. (shrink)

Urban animals can benefit from living in cities, but this also makes them vulnerable as they increasingly depend on the advantages of urban life. This article has two aims. First, I provide a detailed analysis of the concept of captivity and explain why it matters to nonhuman animals—because and insofar as many of them have a (non-substitutable) interest in freedom. Second, I defend a surprising implication of the account—pushing the boundaries of the concept while the boundaries of cities and human (...) activities expand. I argue for the existence of the neglected problem of pervasive captivity, of which urban wildlife is an illustration. Many urban animals are confined, controlled and dependent, therefore often captive of expanding urban areas. While I argue that captivity per se is value-neutral, I draw the ethical and policy implications of harmful pervasive captivity. (shrink)

What does it mean to be a morally good person? It can be tempting to think that it is simply a matter of performing certain actions and avoiding others. And yet there is much more to moral character than our outward actions. We expect a good person to not only behave in certain ways but also to experience the world in certain ways within.

This study investigates the social–psychological mechanisms leading individuals in organizations to engage in environmental citizenship behaviors, which entail keeping abreast of, and participating in, the environmental affairs of a company. Informed by the corporate greening and organizational behavior literature, we suggested that an employee’s level of involvement in the management of a company’s environmental impact was the overt manifestation of his or her discretionary sense of commitment to environmental concerns in the work context, and that such commitment developed through the (...) interplay of individual, organizational, and supervisory factors. Our general findings support the idea that when environmental protection is valued and encouraged by the company and line managers, organization members are more likely to experience a volitional sense of attachment and responsibility to corporate environmental goals and values, which is enacted through citizenship behaviors. We also expected that individual ecological beliefs would strengthen the environmental commitment of employees via identification with, and adherence to, the socially responsible cause embodied by the organization and its managerial staff. But it did not. On the contrary, the data indicated that corporate environmental policy is more likely to influence an employee’s level of environmental commitment when he or she holds weak versus strong personal ecological beliefs. Theoretical and managerial implications of our findings are discussed. (shrink)

Syllogisms (e.g. “All A are B; All B are C; What is true about A and C?”) are a long‐studied area of human reasoning. Riesterer, Brand, and Ragni compare a variety of models to human performance and show that not only do current models have a lot of room for improvement, but more importantly a large part of this improvement must come from examining individual differences in performance.

De réchauffement climatique en scandale sanitaire et d’OGM en catastrophe nucléaire, la science et la technique sont devenues des questions pleinement politiques, tandis que la « technoscience » vient interroger les concepts moraux les mieux ancrés. Pourtant, ce qui devrait susciter un intérêt soutenu ne génère souvent que la résignation de « n’y rien comprendre » - ce qui laisse le champ libre aux lobbies de la technologie et aux bluffs scientifiques les plus éhontés. Qu’y puis-je, direz-vous, si la science (...) m’a toujours été présentée comme rébarbative et « chiantifique », et si la parole des experts, même de mauvaise foi, couvre la mienne quand je tente de m’exprimer à ce sujet? Et puis, cela me concerne-t-il vraiment? Un seul remède : se plonger dans ce dictionnaire, qui vise moins à « faire passer » de l’information qu’à donner les outils nécessaires pour dégonfler les prétentions excessives de la technoscience. De « abeille » à « zz » en passant par « sérendipité » et « post-humanisme », c’est tout le domaine de la science et de la technologie qui se révèle non seulement comme digne d’être exploré mais aussi comme susceptible d’être squatté efficacement : les théories les plus décoiffantes, les idées les moins convenues et les personnages les plus inattendus font de ce domaine un incomparable tremplin pour l’imagination, et incitent à pénétrer sans crainte dans ce que tant d’autres aimeraient continuer à considérer comme une chasse gardée. (shrink)

Written seven years after publication of his Search after Truth, Malebranche's Treatise on Ethics develops a detailed, experimental science of ethics in two parts - the ethics of virtue and the ethics of duty.

In a 1993 paper, I argued that empirical treatments of the epistemologyused by scientists in experimental work are too abstract in practice tocounter relativist efforts to explain the outcome of scientificcontroversies by reference to sociological forces. This was because, atthe rarefied level at which the methodology of scientists is treated byphilosophers, multiple mutually inconsistent instantiations of theprinciples described by philosophers are employed by contestingscientists. These multiple construals change within a scientificcommunity over short time frames, and these different versions ofscientific methodology (...) can determine the outcome of a controversy. Iillustrated with a comparatively detailed analysis of the methodologyused by biologists debating the existence of an entity called thebacterial mesosome between the mid-1950s and the mid-1970s. This 1993piece has drawn several critiques in the philosophical literature. Inthis present piece I respond to these critiques and argue that they failto address the core argument of the original paper, and I reflectfurther on the methodologies of philosophers of science pursuingempirical or `naturalistic' epistemology. (shrink)

What has become generally known as the Berlin School of Logical Empiricism constitutes a philosophical movement that was erected on foundations laid by Albert Einstein. His revolutionary work in physics had a profound impact on philosophers interested in scientific issues, prominent among them Paul Oppenheim and Hans Reichenbach, the founding fathers of the school, who joined in viewing him as their hero among philosopher-scientists. Overall the membership of this school falls into three groups. The founding generation was linked by the (...) circumstance that both Grelling and Reichenbach were collaborators of Oppenheim; the middle generation by the fact that both Hempel and Helmer were students of Reichenbach's in Berlin; and the younger generation by the fact that all of its members were students and disciples either of Reichenbach's or of Hempel's in the USA. Three stages are at issue: an initial phase in Berlin, a transatlantic migration, and a continuation in the U.S.A.--principally in Pittsburgh. (shrink)

Creating an integrated design space can be successful only if researchers agree on how to define and measure a certain phenomenon of interest. Adversarial collaborations and mathematical modeling can aid in reaching the necessary level of agreement when researchers depart from different theoretical perspectives.

The elimination of subjectivity through brain research and the replacement of so-called ‘folk psychology’ by a neuroscientifically enlightened worldview and self-conception has been both hoped for and feared. But this cultural revolution is still pending. Based on nine months of fieldwork on the revival of hallucinogen research since the ‘Decade of the Brain,’ this paper examines how subjective experience appears as epistemic object and practical problem in a psychopharmacological laboratory. In the quest for neural correlates of (drug-induced altered states of) (...) consciousness, introspective accounts of test subjects play a crucial role in neuroimaging studies. Firsthand knowledge of the drugs’ flamboyant effects provides researchers with a personal knowledge not communicated in scientific publications, but key to the conduct of their experiments. In many cases, the ‘psychedelic experience’ draws scientists into the field and continues to inspire their self-image and way of life. By exploring these domains the paper points to a persistence of the subjective in contemporary neuropsychopharmacology. (shrink)

This book is the first extensive treatment of Husserl's phenomenology of time-consciousness. Nicolas de Warren uses detailed analysis of texts by Husserl, some only recently published in German, to examine Husserl's treatment of time-consciousness and its significance for his conception of subjectivity. He traces the development of Husserl's thinking on the problem of time from Franz Brentano's descriptive psychology, and situates it in the framework of his transcendental project as a whole. Particular discussions include the significance of time-consciousness for (...) other phenomenological themes: perceptual experience, the imagination, remembrance, self-consciousness, embodiment, and the consciousness of others. The result is an illuminating exploration of how and why Husserl considered the question of time-consciousness to be the most difficult, yet also the most central, of all the challenges facing his unique philosophical enterprise"--Provided by publisher. (shrink)

(in press, under contract with MIT Press, accepted on June 30th, 2006). Attention, Information and Epistemic Perception. In Terzis, G. & Arp, R. (Eds) Information and the Living Systems: Essays in the Philosophy of Biology. The MIT Press. (14,000 words).

This article aims at understanding how "ethical public issues" are created, and dealt within a public arena. Here, we view ethical public issues as social constructs, which are the results of issue framing contests. Such an approach will enable us to understand how ethical public issues emerge and are shaped by strategizing actors (including firms, NGOs, the media, and governments), in an attempt to impose their own definition and preferred solution to the issue. We also propose key factors which explain (...) the success of a framing attempt, and evidence of such success. The empirical case of the labor conditions in West Africa's cocoa industry is used to illustrate this theoretical framework and methodological approach. (shrink)

This paper intends to bring Austinian themes into methodological discussion about models. Using Austinian conceptual vocabulary, I argue that models perform actions in and outside of the academic field. This multiplicity of fields induces a variety of felicity conditions and types of performed actions. If for example, an inference from a model is judged according to some epistemological criteria in the scientific field, the representation of the world which the model carries will not be judged by the same criteria outside (...) the scientific field. A model can be considered as a standard in a strict scientific framework, while not being used as part of public policies, or vice versa. However, we focus on the dynamics between different fields. (shrink)

This article argues for a novel approach to the measurement of freedom of choice, on which the availability of an option is a matter of degree, rather than a bivalent matter of being either available or not. This approach is motivated by case studies involving weakness of will, where deficiencies in willpower seem to impair individual freedom by making certain alternatives much harder to pursue. This approach is perfectly general, however: its graded analysis of option availability can be extended to (...) cases where weakness of will is not involved and can be used to generalize numerous existing measures of freedom. (shrink)

We present a new proof of soundness/completeness of tableaux with respect to dialogical games in Classical First-Order Logic. As far as we know it is the first thorough result for dialogical games where finiteness of plays is guaranteed by means of what we call repetition ranks.

I offer a Buddhist-inspired account of how patience can count as a moral virtue, arguing that virtuous patience involves having a perspective on the place of our own desires and values among others and a sense of their relative importance.

In Study 1, we examined the moderating impact of alexithymia (i.e., a difficulty identifying and describing feelings to other people and an externally oriented cognitive style) on the automatic processing of affective information. The affective priming paradigm was used, and lower priming effects for high alexithymia scorers were observed when congruent (incongruent) pairs involving nonverbal primes (angry face) and verbal target were presented. The results held after controlling for participants' negative affectivity. The same effects were replicated in Studies 2 and (...) 3, with trait anxiety and depression entered as additional covariates. In Study 3, no moderating impact of alexithymia was found for verbal-facial pairs suggesting that the results cannot be merely explained in terms of transcoding limitations for high alexithymia scorers. Overall, the present results suggest that alexithymia could be related to a difficulty in processing and automatically using high arousal emotional information to respond to concomittant behavioural demands. (shrink)

Based on anthropological fieldwork on the revival of hallucinogen research as well as on the epistemic culture of neurophilosophy, this Common Knowledge guest column examines two very different philosophical engagements with psychedelic drugs. In Thomas Metzinger's evidence-based philosophy of mind, hallucinogens help to operationalize questions about the nature of consciousness. While this project contributes to the great divide between empirically enlightened moderns and tradition-oriented premoderns, Metzinger's neurophilosophical reanimation of the ancient conception of philosophy as cultura animi can build a bridge (...) to Aldous Huxley's perennial philosophy, which has informed the psychedelic intelligentsia like no other body of thought. In the sixteenth century, the philosophia perennis grew out of a decidedly nonmodern philosophy of religion that sought to suture the historical and cultural cracks that would come to define modernity. This essay argues that neurophilosophy and ethnographic studies of consciousness cultures could function as critical correctives in a contemporary rearticulation of perennial philosophy. (shrink)

Cette édition numérique a été réalisée à partir d'un support physique, parfois ancien, conservé au sein du dépôt légal de la Bibliothèque nationale de France, conformément à la loi n° 2012-287 du 1er mars 2012 relative à l'exploitation des Livres indisponibles du XXe siècle. Pages de début Chapitre premier - La leçon des masques Première partie - L'imitation et son modèle introuvable Chapitre II - L'art comme illusionnisme Chapitre III - L'art selon Diderot : idéal de la vérité ou vérité (...) de l'idéal? Chapitre IV - La nature comme dictionnaire de l'art Chapitre V - L'art comme réformation de la nature Chapitre VI - La peinture hollandaise selon Hegel : le réalisme dans l'art comme déréalisation de la nature Chapitre VII - La nature comme effet de style Deuxième partie - Le monde de l'art 1 - L'art et la nature2 - L'expérience esthétique Bibliographie Index Pages de fin. (shrink)

Cet ouvrage est consacre a l'etude de la distinction linguistique entre noms massifs (lait, mobilier, desordre, amour...) et noms comptables (chat, equipe, combat, chose...). Les premiers sont normalement invariables, tandis que les seconds s'emploient librement au singulier et au pluriel. Apres avoir etabli qu'il s'agit bien d'une distinction morpho-syntaxique, l'ouvrage discute la possibilite de caracteriser semantiquement cette distinction. Les recherches existantes ne tiennent compte, essentiellement, que des noms s'appliquant au domaine materiel. Ce travail, au contraire, examine en detail aussi bien (...) les noms concrets qu'abstraits. Il propose de redefinir les proprietes souvent attribuees aux noms massifs (references distributive et cumulative), grace, notamment, a une nouvelle notion de partie. Concernant les noms comptables, il montre qu'aucune propriete purement semantique n'est necessaire pour qu'un nom soit de ce type. L'ouvrage se termine par l'analyse des conversions (emplois massifs des noms comptables, et vice versa), et du role qu'y jouent les facteurs pragmatiques. (shrink)

Henrich et al.’s article fleshes out in a very useful and timely manner comments often heard but rarely published about the extraordinary cultural imbalance in the recruitment of participants in psychology experiments and the doubt this casts on generalization of findings from these “weird” samples to humans in general. The authors mention that one of the concerns they have met in defending their views has been of a methodological nature: “the observed variation across populations may be due to various methodological (...) artifacts that arise from translating experiments across contexts” (sect. 7.2, para. 1). Here we want to express a less sweeping methodological concern. While accepting the general conclusions and recommendations of the article, we believe they should be complemented with a.. (shrink)

Se plantea la cuestión del papel de la armonía en la concepción de la racionalidad de Leibniz. Se sitúa esta noción en el marco de la metafísica de la individualidad sistémica, y aparece en dos lugares concretos. En primer lugar en el eje categorial uniformidad-diversi­dad, como principio de equilibrio entre ambos polos. Y en segundo lugar, aparece la noción de armonía en el nivel último de la racionalidad, concretamente en plano de la lógica de los principios. Este nivel se rige (...) por el principio general del orden, y precisamente este principio es explicado por Leibniz frecuentemente en relación con la armonía. (shrink)

Para calificar la estética posmodernista, que responde a la entrada en la era posmoderna, marcada por la ausencia de una visión unitaria y global del mundo, los teóricos de los años 70 privilegiaron el concepto de “heterogeneidad”, que en la década siguiente y parte de los años 90, dejó paso al de “sincretismo”, “mestizaje” o “creolidad”. A partir de los años 90 y, sobre todo, desde la primera década del tercer milenio, el concepto de “hibridez” ocupa un lugar destacado debido, (...) en parte, a la influencia de los estudios poscoloniales. Uno de los primeros en utilizar dicho concepto, en 1990, fue el crítico cultural argentino Néstor García Canclini, pero no profundizó sobre la hibridez de las obras literarias. Por consiguiente, cabe definir, en primer lugar, esta noción proteiforme, utilizada en nuestros días en numerosos campos. (shrink)

This article offers a justification for accommodating claims of conscience. The standard justification points to the pain that acting against one’s conscience entails. But that defense cannot make sense of the state’s refusal to accommodate individuals where the law interferes with their deeply meaningful but nonmoral projects. An alternative justification, we argue, arises once one recognizes the connection between conscience and moral address: One’s lived moral convictions determine when and with what force one can hold others to account. Acting against (...) one’s convictions can undermine one’s standing to blame others who act in similar ways. When the state compels someone to act against conscience, it renders her complicit in conduct she takes to be wrong and thereby impairs her ability to condemn similar conduct in the future, in a manner akin to the hypocrite. The reason the state should not compel people to act against conscience, then, is that doing so would undercut their moral standing. (shrink)

The causal view of categories assumes that categories are represented by features and their causal relations. To study the effect of causal knowledge on categorization, researchers have used Bayesian causal models. Within that framework, categorization may be viewed as dependent on a likelihood computation (i.e., the likelihood of an exemplar with a certain combination of features, given the category's causal model) or as a posterior computation (i.e., the probability that the exemplar belongs to the category, given its features). Across three (...) experiments, in combination with computational modeling, we offer evidence that categorization is better accounted for by assuming that people compute posteriors and not likelihoods, though both probabilities are closely related. This result contrasts with existing analyses of causal-based categorization, which assume that likelihood computations give a good approximation of human judgments. We also find that people are able to compute likelihoods in a closely related task that elicits judgments of consistency rather than category membership judgments. Our analyses show that people do use causal probabilistic information as prescribed by a Bayesian model but that they flexibly compute likelihoods or posteriors depending on the task. We discuss our results in relation to the relevant literature on the topic. (shrink)

Cette édition numérique a été réalisée à partir d'un support physique, parfois ancien, conservé au sein du dépôt légal de la Bibliothèque nationale de France, conformément à la loi n° 2012-287 du 1er mars 2012 relative à l'exploitation des Livres indisponibles du XXe siècle. En montrant que la conscience pure est pure attente, cet essai décrit comment l'attente structure transcendantalement toute représentation que nous puissions avoir du temps. « Copyright Electre » Pages de début Première partie - La conscience du (...) temps 1 - Le sens du temps 2 - Phénoménologie de l'attente Deuxième partie - Ontologie du temps 3 - Réalité du temps 4 - Continuité et discontinuité 5 - Substantialité de la médiation : une ontologie de l'ambiguïté Bibliographie Index Pages de fin. (shrink)