The paper discusses the concept of the cognitive niche and distinguishes the latter from the metabolic niche. By using these posits I unpack certain ideas that are crucial for the enactivist movement, especially for its original formulation proposed by Varela, Thompson and Rosh. Drawing on the ontology of location, boundaries, and parthood, I argue that enacting the world can be seen as the process of cognitive niche construction. Moreover, it turns out that enactivism—as seen through the lens of the conceptual (...) framework proposed in the paper—considers cognition as a kind of connection between the subject and the world. This post is pointed to as the key idea laid down in enactivism. (shrink)

The aim of this paper is to introduce, elucidate and defend the usefulness of a variant of grounding, or metaphysical explanation, that has the feature that the grounds explain of some states of affairs that one of them obtains without explaining which one obtains. I will dub this variant arbitrary grounding. After informally elucidating the basic idea in the first section, I will provide three metaphysical hypotheses that are best formulated in terms of arbitrary grounding in the second section. The (...) third section will be concerned with the relation between arbitrary grounding and non-arbitrary grounding. The fourth section will compare arbitrary grounding to two extant proposals in the literature. (shrink)

While classifications of mental disorders have existed for over one hundred years, it still remains unspecified what terms such as 'mental disorder', 'disease' and 'illness' might actually denote. While ontologies have been called in aid to address this shortfall since the GALEN project of the early 1990s, most attempts thus far have sought to provide a formal description of the structure of some pre-existing terminology or classification, rather than of the corresponding structures and processes on the side of the patient. (...) We here present a view of mental disease that is based on ontological realism and which follows the principles embodied in Basic Formal Ontology and in the application of BFO in the Ontology of General Medical Science. We analyzed statements about what counts as a mental disease provided in the research agenda for the DSM-V, and in Pies' model. The results were used to assess whether the representational units of BFO and OGMS were adequate as foundations for a formal representation of the entities in reality that these statements attempt to describe. We then analyzed the representational units specific to mental disease and provided corresponding definitions. Our key contributions lie in the identification of confusions and conflations in the existing terminology of mental disease and in providing what we believe is a framework for the sort of clear and unambiguous reference to entities on the side of the patient that is needed in order to avoid these confusions in the future. (shrink)

The development of genomic technologies has seemed almost magical. Excitement about it, both in medicine and among the public, stems from the belief that genomic techniques will illuminate the causes of health and disease, will lead to effective interventions for both rare and common genetic conditions, and will inform reproductive decision‐making. Novel diagnostic tools, however, are often deployed before targeted therapies are developed, tested, or available and before their psychosocial implications are explored. Newer technologies such as prenatal whole exome screening (...) are seen as offering “decisional autonomy” to expectant parents, although such technologies identify information about genetic sequencing that may not have clear meaning. The “therapeutic gap” between the ability to conduct genetic sequencing and the ability to fully understand what the test results mean, much less what treatments to offer, leaves families with complex and unclear information they cannot act upon with confidence during pregnancy. In this essay, we will consider the psychosocial and ethical implications of such assumptions—and of the uncertain information produced by these technologies—for individuals and families and for societal aspects such as medical service usage and demographic inequities. (shrink)

This volume has its already distant or1g1n in an inter national conference on Evolutionary Epistemology the editors organized at the University of Ghent in November 1984. This conference aimed to follow up the endeavor started at the ERISS (Epistemologically Relevant Internalist Sociology of Science) conference organized by Don Campbell and Alex Rosen berg at Cazenovia Lake, New York, in June 1981, whilst in jecting the gist of certain current continental intellectual developments into a debate whose focus, we thought, was in (...) danger of being narrowed too much, considering the still underdeveloped state of affairs in the field. Broadly speaking, evolutionary epistemology today con sists of two interrelated, yet qualitatively distinct inves tigative efforts. Both are drawing on Darwinian concepts, which may explain why many people have failed to discriminate them. One is the study of the evolution of the cognitive apparatus of living organisms, which is first and foremost the province of biologists and psychologists (H. C. Plotkin, Ed. , Learning, Development, and Culture: Essays in Evolu tionary Epistemology, New York, Wiley, 1984), although quite a few philosophers - professional or vocational - have also felt the need to express themselves on this vast subject (F. M. Wuketits, Ed. , Conce ts and Approaches in Evolutionary Epistemology, Dordrecht Boston, Reidel, 1984). The other approach deals with the evolution of science, and has been dominated hitherto by (allegedly) 'naturalized' philosophers; no book-length survey of this literature is available at present. (shrink)

We performed a qualitative analysis of the Thesaurus in order to assess its conformity with principles of good practice in terminology and ontology design. We used both the on-line browsable version of the Thesaurus and its OWL-representation (version 04.08b, released on August 2, 2004), measuring each in light of the requirements put forward in relevant ISO terminology standards and in light of ontological principles advanced in the recent literature. Version 04.08b of the NCI Thesaurus suffers from the same broad range (...) of problems that have been observed in other biomedical terminologies. For its further development, we recommend the use of a more principled approach that allows the Thesaurus to be tested not just for internal consistency but also for its degree of correspondence to that part of reality which it is designed to represent. (shrink)

Quality assurance in large terminologies is a difficult issue. We present two algorithms that can help terminology developers and users to identify potential mistakes. We demon­strate the methodology by outlining the different types of mistakes that are found when the algorithms are applied to SNOMED-CT. On the basis of the results, we argue that both formal logical and linguistic tools should be used in the development and quality-assurance process of large terminologies.

PURPOSE—A substantial fraction of the observations made by clinicians and entered into patient records are expressed by means of negation or by using terms which contain negative qualifiers (as in “absence of pulse” or “surgical procedure not performed”). This seems at first sight to present problems for ontologies, terminologies and data repositories that adhere to a realist view and thus reject any reference to putative non-existing entities. Basic Formal Ontology (BFO) and Referent Tracking (RT) are examples of such paradigms. The (...) purpose of the research here described was to test a proposal to capture negative findings in electronic health record systems based on BFO and RT. METHODS—We analysed a series of negative findings encountered in 748 sentences taken from 41 patient charts. We classified the phenomena described in terms of the various top-level categories and relations defined in BFO, taking into account the role of negation in the corresponding descriptions. We also studied terms from SNOMED-CT containing one or other form of negation. We then explored ways to represent the described phenomena by means of the types of representational units available to realist ontologies such as BFO. RESULTS—We introduced a new family of ‘lacks’ relations into the OBO Relation Ontology. The relation lacks_part, for example, defined in terms of the positive relation part_of, holds between a particular p and a universal U when p has no instance of U as part. Since p and U both exist, assertions involving ‘lacks_part’ and its cognates meet the requirements of positivity. CONCLUSION—By expanding the OBO Relation Ontology, we were able to accommodate nearly all occurrences of negative findings in the sample studied. (shrink)

Ontology is currently perceived as the solution of first resort for all problems related to biomedical terminology, and the use of description logics is seen as a minimal requirement on adequate ontology-based systems. Contrary to common conceptions, however, description logics alone are not able to prevent incorrect representations; this is because they do not come with a theory indicating what is computed by using them, just as classical arithmetic does not tell us anything about the entities that are added or (...) subtracted. In this paper we shall show that ontology is indeed an essential part of any solution to the problems of medical terminology – but only if it is understood in the right sort of way. Ontological engineering, we shall argue, should in every case go hand in hand with a sound ontological theory. (shrink)

Modal potentialism as proposed by Barbara Vetter (2015) is the view that every possibility is grounded in something having a potentiality. Drawing from work by Jessica Leech (2017), Samuel Kimpton-Nye (2021) argues that potentialists can have an S5 modal logic. I present a novel argument to the conclusion that the most straightforward way of spelling out modal potentialism cannot validate an S5 modal logic. Then I will propose a slightly tweaked version of modal potentialism that can validate an S5 modal (...) logic and still does justice to the core claim of potentialism. (shrink)

Imagine coming across an alternative community such that, while they have normative terms like 'ought' with the same action-guiding roles and relationships to each other, their normative terms come to pick out different properties. When we come across such a community, or even just imagine it, those of us who strive to be moral and rational want to ask something like the following: Further Question: Which set of concepts ought we use—theirs or ours? The problem, first raised by Eklund, is (...) that on almost any metasemantic theory, Further Question cannot be stated in a way that captures the spirit of what we want to ask. This is because any way of asking the question makes use of our own normative concepts, and thus their reference is already fixed on the properties that our current normative concepts refer to. Any purported solution to this problem must meet two conditions. First, it must capture the spirit of what Further Question is intuitively attempting to ask. Second, it must reframe the inquiry in a way that makes the answer neither trivial nor ineffable. In this paper, I propose a solution to this problem by appeal to edenic representation, inspired by, but not identical to, Chalmers’ notion of edenic content. The rough idea here is that representation is edenic to the extent that the representational vehicle mirrors, in quality and structure, the represented property. I argue that a reframing of Further Question in terms of edenic representation can capture the spirit of the question, without collapsing it into a question with a trivial or ineffable answer. Thus, the realist about normative properties can face the problem of the alternative normative community head on, without collapsing into incoherence or triviality. If correct, this solution is of further interest to any metanormative realist concerned with metasemantic questions, because it can tell us more about how the proper representation of the robustly normative would look. (shrink)

The principle of plenitude says that every material object coincides with abundantly many further objects that differ in their modal profiles. A necessarily unmanifested disposition is a disposition that necessarily does not manifest. This paper argues that if the principle of plenitude holds, then there are some necessarily unmanifested dispositions. These necessarily unmanifested dispositions will be argued to evade some objections against the cases of necessarily unmanifested dispositions put forward by Carrie Jenkins and Daniel Nolan.

It is widely acknowledged that some truths or facts don’t have a minimal full ground [see e.g. Fine ]. Every full ground of them contains a smaller full ground. In this paper I’ll propose a minimality constraint on immediate grounding and I’ll show that it doesn’t fall prey to the arguments that tell against an unqualified minimality constraint. Furthermore, the assumption that all cases of grounding can be understood in terms of immediate grounding will be defended. This assumption guarantees that (...) the proposed minimality constraint is significant for all cases of grounding. With its help one can get a clear grip on the relevance of grounding, a feature that will be put to use in the penultimate section. (shrink)

We present the details of a methodology for quality assurance in large medical terminologies and describe three algorithms that can help terminology developers and users to identify potential mistakes. The methodology is based in part on linguistic criteria and in part on logical and ontological principles governing sound classifications. We conclude by outlining the results of applying the methodology in the form of a taxonomy different types of errors and potential errors detected in SNOMED-CT.

This study examines the public's and physicians' willingness to support deception of insurance companies in order to obtain necessary healthcare services and how this support varies based on perceptions of physicians' time pressures. Based on surveys of 700 prospective jurors and 1617 physicians, the public was more than twice as likely as physicians to sanction deception (26% versus 11%) and half as likely to believe that physicians have adequate time to appeal coverage decisions (22% versus 59%). The odds of public (...) support for deception compared to that of physicians rose from 2.48 to 4.64 after controlling for differences in time perception. These findings highlight the ethical challenge facing physicians and patients in balancing patient advocacy with honesty in the setting of limited societal resources. (shrink)

If SNOMED CT is to serve as a biomedical reference terminology, then steps must be taken to ensure comparability of information formulated using successive versions. New releases are therefore shipped with a history mechanism. We assessed the adequacy of this mechanism for its treatment of the distinction between changes occurring on the side of entities in reality and changes in our understanding thereof. We found that these two types are only partially distinguished and that a more detailed study is required (...) to propose clear recommendations for enhancement along at least the following lines: (1) explicit representation of the provenance of a class; (2) separation of the time-period during which a component is stated valid in SNOMED CT from the period it is (or has been) valid in reality, and (3) redesign of the historical relationships table to give users better assistance for recovery in case of introduced mistakes. (shrink)

The differential activation hypothesis (DAH; Teasdale, 1988) proposes that individuals who are vulnerable to depression can be distinguished from non-vulnerable individuals by the degree to which negative thoughts and maladaptive cognitive processes are activated during sad mood. While retrieval of negative autobiographical memories is noted as one such process, the model does not articulate a role for deficits in recalling positive memories. Two studies were conducted to compare the autobiographical memory characteristics of never-depressed and formerly depressed individuals following a sad (...) mood induction. In Study 1, features of negative memories of never-depressed and formerly depressed individuals did not differ, either in neutral or sad mood. For positive memories, groups did not differ in neutral mood, but following a sad mood induction, formerly depressed individuals rated their positive memories as less vivid than their never-depressed counterparts. Study 2 examined positive autobiographical memory features more comprehensively and replicated the finding that in a sad mood formerly depressed individuals recalled less vivid positive memories than never-depressed controls. These findings suggest that the phenomenological features of positive memories could represent an important factor in depressive vulnerability, and, more broadly, that depression may be associated with a deficit in the processing of positive material. (shrink)

This paper aims to elucidate a kind of ignorance that is more fundamental than a momentary lack of information, but also not a kind of ignorance that is built into the subject’s cognitive apparatus such that the subject can’t do anything about it. The paper sets forth the notion of cognitive confinement, which is a contingent, yet relatively stable state of being structurally or systematically unable to gain information from an environment, determined by patterns of interaction between the subject and (...) the world. In order to unpack the idea of cognitive confinement the paper discusses niche construction theory, and then, in greater detail, the notion of cognitive niche once proposed by John Tooby and Irven DeVore. Cognitive confinement is here imagined as a pathologized form of cognitive niche. This posit is substantiated by referring to a case that has come to the fore in recent years and raised debate around the world: the rise of so-called filter bubbles. They turn out to be instantiations of a more general phenomenon of cognitive confinement. (shrink)

We explore the different meanings of “quantum uncertainty” contained in Heisenberg’s seminal paper from 1927, and also some of the precise definitions that were developed later. We recount the controversy about “Anschaulichkeit”, visualizability of the theory, which Heisenberg claims to resolve. Moreover, we consider Heisenberg’s programme of operational analysis of concepts, in which he sees himself as following Einstein. Heisenberg’s work is marked by the tensions between semiclassical arguments and the emerging modern quantum theory, between intuition and rigour, and between (...) shaky arguments and overarching claims. Nevertheless, the main message can be taken into the new quantum theory, and can be brought into the form of general theorems. They come in two kinds, not distinguished by Heisenberg. These are, on one hand, constraints on preparations, like the usual textbook uncertainty relation, and, on the other, constraints on joint measurability, including trade-offs between accuracy and disturbance. (shrink)

This paper targets the concept of enactment as a genuinely metaphysical idea. Its goals are two-fold. First, a reappraisal of enactment in its proper historical context, as well as an articulation of the core innovations enactment brings to traditional metaphysics. Here the idea of 'productive' cognition, as I provisionally term it, comes to the fore. The second goal is a reinterpretation of certain themes from traditional metaphysics, including the key question of why there is something rather than nothing, so as (...) to make it more open to insights originating from enactivism. For that, the concept of 'situated metaphysics' is introduced and elaborated upon. (shrink)

One important challenge for contingentists is that they seem to be unable to account for the meaning of some apparently meaningful modal discourse that is perfectly intelligible for necessitists. This worry is particularly pressing for higher-order contingentists, contingentists who hold that it is not only contingent which objects there are, but also contingent which semantic values there are for higher-order variables to quantify over. Objections against higher-order contingentism along these lines have been presented in Williamson (Mind 119(475):657–748, 2010; Modal logic (...) as metaphysics, Oxford University Press, 2013, ch. 7), and Fritz and Goodman (Mind 126(504):1063–1108, 2017). This paper presents a way for contingentists to respond to these challenges. The upshot is that the contingentist can account for the meaningfulness of the problematic modal claims by pretending necessitism to be true, but in some cases it turns out to be indeterminate whether they are true. I defend this strategy against the objections against pretence-strategies presented in Fritz and Goodman (Mind 126(504):1063–1108, 2017, §4). Furthermore, I defend the plausibility of the resulting indeterminacy from the contingentist’s perspective. (shrink)

First Published in 1998. Routledge is an imprint of Taylor & Francis, an informa company.

In this paper, I argue for two principles to determine the temporal interpretation of modal sentences in English, given a theory in which modals are interpreted against double conversational backgrounds and an ontology in which possible worlds branch towards the future, The Disparity Principle requires that a modal sentence makes distinctions between worlds in the modal base. The Non- disparity Principle requires that a modal sentence does not make distinctions on the basis of facts settled at speech time. Selection of (...) the modal base will set these principles against each other, or allow for their cooperative interaction. For a root modal base, there is a conflict and disparity wins. The resulting interpretation is future. For a non-root modal base, the principles cooperate. Non-disparity determines a non-future interpretation and disparity requires the sentence to go beyond what is known by the speaker. (shrink)

Digital Rights Management (DRM) covers the description, identification, trading, protection, monitoring and tracking of all forms of rights over both tangible and intangible assets. The Digital Object Identifier (DOI) system provides a framework for the persistent identification of entities involved in this domain. Although the system has been very well designed to manage object identifiers, some important questions relating to the creation and assignment of identifiers are left open. The paradigm of a Referent Tracking System (RTS) recently advanced in the (...) healthcare and life sciences environment is able to fill these gaps. This is demonstrated by pointing out inconsistencies in the existing DOI models and by showing how they can be corrected using an RTS. (shrink)

To date, business ethicists, corporate social responsibility scholars as well as management theorists have been slow to provide a comprehensive and critical scrutiny of the Living Wage concept. The aim of this article, therefore, is to conceptualize the living wage in its philosophical as well as practical dimensions in order to open up the ethical implications of its introduction and implementation by companies. We set out the legal, socio-institutional and economic contexts for the debates around the LW and review arguments (...) for, and against, it. Key philosophical arguments from the perspectives of sustainability, capability and externality are invoked and discussed in order to demonstrate the issues and challenges involved for companies, state and civil society actors. Relevant examples from the private sector are examined to demonstrate some of the practical issues involved when the LW is introduced by employers. The article also recommends avenues for a research agenda into the LW for business ethicists, CSR and management researchers in contexts such as the UK, where a voluntary, rather than mandatory, approach to the implementation of the LW is adopted. (shrink)

Non-naturalism is the view that normative properties are response-independent, irreducible to natural properties, and causally inefficacious. An underexplored question for non-naturalism concerns the metasemantics of normative terms. Ideally, the non-naturalist could remain ecumenical, but it appears they cannot. Call this challenge the metasemantic challenge. This chapter suggests that non-naturalists endorse an epistemic account of reference determination of the sort recently defended by Imogen Dickie, with some modifications. An important implication of this account is that, if correct, a fully fleshed out (...) moral epistemology will simultaneously rebut metasemantic objections to non-naturalism. Thus, both the metasemantic and the more widely discussed epistemological challenges in effect amount to one. Before setting out the positive view, the chapter considers why all of the traditional metasemantic theories cause trouble for the non-naturalist. This includes discussions of teleosemantics, conceptual role semantics, as well as Schroeter and Schroeter’s “connectedness” model. (shrink)

Affective congruency effects in the evaluation task can be explained by either spreading of activation or response competition. Eliminating effects of response compatibility by using other tasks (semantic categorisation, naming task) typically also eliminates affective congruency effects. However, there is no need for processing the affective information of the stimuli in these tasks either, which could be necessary for an affectively mediated spreading of activation (Spruyt et al., 2007, 2009, 2012). We introduced a new task to further test this hypothesis. (...) The valent/neutral-categorisation task does not confound affective congruency with response compatibility, but still requires a processing of the stimuli's valence. No affective congruency effect was obtained with this task in two experiments, disfavouring a conditional spreading activation account. On the other hand, a significant priming effect was found for associated word pairs in Experiment 1, providing evidence for the sensitivity of the task to detect spreading activation processes. (shrink)

While Adorno has tended to be read as a critic of the administered world and the consumer industry rather than a Marxist, Adorno and Marx establishes Adorno's negative dialectics as fundamental for understanding Marx's critique of political economy. This conception of the critique of political economy as a critical theory marks both a radical departure from traditional Marxist scholarship and from traditional readings of Adorno's work and warns against identifying Adorno with Marx or Marx with Adorno. Rather, it highlights the (...) intersection between Adorno's critical theory and Marx's critique of political economy that produces a critical theory of economic objectivity that moves beyond Marxian economics and Adornonian social theory. Adorno and Marx offers an ingenious account of critical social theory. Its subversion of the economic categories of political economy contributes to the cutting-edge of contemporary social theory and its critique of social practice. (shrink)

Referent tracking (RT) is a new paradigm, based on unique identification, for representing and keeping track of particulars. It was first introduced to support the entry and retrieval of data in electronic health records (EHRs). Its purpose is to avoid the ambiguity that arises when statements in an EHR refer to disorders or other entities on the side of the patient exclusively by means of compound descriptions utilizing general terms such as ‘pimple on nose’ or ‘small left breast tumor’. In (...) this paper, we describe the theoretical foundations of this paradigm and show how it is being applied to the solution of analogous problems of ambiguous identification in the fields of digital rights management, corporate memories and decision algorithms. (shrink)

Against the background of the contemporary debate about financialisation, the paper conceptualises the capitalist labour economy as fundamentally a monetary system. It argues that money is not a capitalist means of organising its labour economy but that it is rather a capitalist end. The argument examines and finds wanting conceptions of money in political economy, including Keynesianism and neoliberalism, and argues that the debate about financialisation is fundamentally based on the propositions of political economy. It holds that Marx’s critique of (...) political economy conceives of money as the form of value and expounds money-making as the purpose of the capital labour economy. Thus, the labour theory of value is fundamentally a monetary theory of value, labour is the means of valorisation, and that is, of money in process, and as such capital. Making money out of money is capital as its most rational. In the form of credit, money posits wealth as a claim on future surplus value. (shrink)

One of Plato’s aims in the Phaedrus seems to be to outline an ‘ideal’ form of rhetoric. But it is unclear exactly what the ‘true’ rhetorician really looks like, and what exactly his methods are. More broadly, just how does Plato see the relation between rhetoric and philosophy? I argue, in light of Plato’s epistemology, that the “true craft (techne) of rhetoric” which he describes in the Phaedrus is a regulative, but also an unattainable ideal. Consequently, the mythical palinode in (...) the dialogue is not (as some have claimed) an example of the true techne—and indeed it could not be. But neither is dialectic. Rather, dialectic is the closest approximation of the true techne of rhetoric which can be had; that is to say, dialectic is the best and highest kind of psychagogia (a ‘leading of the soul through words’). Plato’s purpose in describing the “true techne of rhetoric”, then, is not to reform or to rehabilitate rhetoric, but to urge us to abandon it in favor of the philosophical life. One implication of this is that Plato is just as hostile toward rhetoric as he is in the Gorgias. (shrink)

This is the second of two articles in which I reflect on “generalized Darwinism” as currently discussed in evolutionary economics. In the companion article (Callebaut, Biol Theory 6. doi: 10.1007/s13752-013-0086-2, 2011, this issue) I approached evolutionary economics from the naturalistic perspectives of evolutionary epistemology and the philosophy of biology, contrasted evolutionary economists’ cautious generalizations of Darwinism with “imperialistic” proposals to unify the behavioral sciences, and discussed the continued resistance to biological ideas in the social sciences. Here I assess Generalized Darwinism (...) as propounded by Geoffrey Hodgson, Thorbjørn Knudsen, and others, concentrating on the roles of theory and model building in science (and the roles of analogy and metaphor therein), generative replication, and the relation between selection and self-organization. I then point to advances in current biology that promise to be more fruitful as sources of inspiration for evolutionary economics than the project to generalize Darwinism in its current, “hardened Modern Synthesis” form; and I draw some conclusions. (shrink)

Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components. Since malaria parasites can be present even in the absence of malaria manifestations, and since symptoms of malaria can be manifested even in the absence of malaria parasites, malaria diagnosis raises important issues for the adequate understanding of disease, etiology and diagnosis. One approach to the resolution of these issues adopts a realist view, according to which the needed (...) clarifications will be derived from a careful representation of the entities on the side of the patient which form the ultimate truthmakers for clinical statements. We here address a challenge to this realist approach relating to the diagnosis of malaria, and show how this challenge can be resolved by appeal to Basic Formal Ontology (BFO) and to the Ontology for General Medical Science (OGMS) constructed in its terms. (shrink)

Context: Von Foerster’s concept of eigenbehavior can be recognized against the broader context of enactivism as it has been advocated by Varela, Thompson and Rosch, by Noë and recently by Hutto and Myin, among others. This flourishing constellation of ideas is on its way to becoming the new paradigm of cognitive science. However, in my reading, enactivism, putting stress on the constitutive role of action when it comes to mind and perception, faces a serious philosophical challenge when attempting to account (...) for the way we actually perceive our environments, most importantly for the fact that we perceive things or objects. Von Foester’s eigenbehavior is understood here as a concept supposed to take on this challenge. Problem: In this article I tackle the following issues: Enactivism must be able to account for the apparent stability of the perceived world: this is not a realm of a never-ending flux of stimuli; it is a realm of stable things. Enactivism is committed to the anti-Cartesian endeavor seeking to bridge the gap between the inner and the outer; between the subjective and the objective. Now, these two points constrain each other so that one cannot address simply by regarding the apparent stability of things as a projection that springs out of the internal machinery binding inputs with outputs. This is because the very idea of such an internal machinery opposes, i.e., it employs the Cartesian dichotomy. So, enactivism is in need of an account of that would not oppose its anti-Cartesian commitment. Method: I introduce the ontology of location and niche theory, as it has been brought forth by Varzi, Casati, and Smith, and develop it so that it can be used in the philosophy of mind. This is a conceptual, semi-formal philosophical analysis. Results: I shall come up with the idea of object conceived of a product of action, and - drawing on von Foerster’s central idea - as a product of coordination of perceptions. Yet, it is not coordination of stimuli but coordination of cognitive connections. The notion of connection is thus articulated in the article and cast as the central concept in my proposal. Implications: We are able to account for both and (2. The apparent stability of the perceived world is due to the setting up and maintaining of connections between the perceiver and the things perceived, resulting in the establishment of what I call a cognitive niche. Constructivist content: Constructivism, broadly construed, takes, in my reading, a negative stance in the first place. Namely, it opposes what I call the metaphysics of the ready-made world. So, it holds that there is no ready-made reality; however it remains open when it comes to positive claims: a mind-independent reality does not exist at all or it does exist but it is not ready-made and as such it must be brought to completion, so to speak, or enacted, as Varela et al. would say, by a cognitive subject. In this article, I follow the latter and address one specific issue: how the enacted world gains its relatively stable architecture. (shrink)

For corporate memory and enterprise ontology systems to be maximally useful, they must be freed from certain barriers placed around them by traditional knowledge management paradigms. This means, above all, that they must mirror more faithfully those portions of reality which are salient to the workings of the enterprise, including the changes that occur with the passage of time. The purpose of this chapter is to demonstrate how theories based on philosophical realism can contribute to this objective. We discuss how (...) realism-based ontologies (capturing what is generic) combined with referent tracking (capturing what is specific) can play a key role in building the robust and useful corporate memories of the future. (shrink)

Der exponierte erste Aphorismus des lezten Teils von Ecce Homo ist einer der herausforderndsten und erschreckendsten in Nietzsches Werk. Er handelt im Kern von der "Umwerthung aller Werthe" alst einem "Akt höchster Selbstbesinnung der Menschheit", der Nietzche zum Schicksal geworden sei und durch den er nun zum Schicksal für die Philosophie und die Menschheit werde. Der Aphorismus galt vielen als Belag dafür, dass Nietzsches Wahnsinn bereits ausgebrochen sei: als Größenwahnsinn. Doch Ecce Homo lässt in seiner klaren und konsequenten Anlage so (...) wenig wie Der Antichrist, den es vorbereiten sollte, Zeichen der Verwirrung erkennen, und Nietzsche had auch früher schon herausfordernd von seiner Aufgabe gesprochen: als Einzelner die Menschheit und die Kultur auf eine neue Stufe zu heen. man wird Nietzsches Werk nur angemessen verstehen können, wenn man auch diesem Aphorismus seinen Ort in ihm geben kann. Die folgende Abhandlung versucht ein kontextuelle Interpretation des Aphorismus: eine Interpretation aus seinem eigenen Kontext, dem Kontext von Ecce Homo und Der Antichrist und dem Kontext von Nietzches Werk im ganzen.The first aphorism of the last chapter of Ecce Homo is oen of the most challenging and terrifying in Nietzsche's work. It essentially deals with the "reevaluation of all values" as an "act of the highest self-assessment of humanity" for which Nietzsche was fated and through which he would become a destiny for philosophy and humanity. The aphorism has served as evidence to some that Nietzsche's madness had already broken out - as megalomania. Yet the clear and careful construction of Ecce Homo, like The Antichrist for which it was supposed to pave the way, do not show any signs of confusion. And Nietzshe had already spoken of his task in a challenging manner: to raise humanity and culture to a new level as a single individual. Correctly understanding Nietzsche requires being able to integrate this aphorism into this work, too. The following essay provides an interpretation of this aphorism based on the context of Ecce Homo and The Antichrist as well as against the background of Nietzsche's work as a whole. (shrink)

In a recent paper in this journal, Jonathan Barker argues against the claim that grounded entities are ontologically innocent. In this paper I defend the ontological innocence of grounded entities against Barker's argument. I tease out an assumption that is crucial for the success of Barker's argument and I show that the defender of ontological innocence can deny this assumption in a motivated way.

The engineering-based approach of synthetic biology is characterized by an assumption that ‘engineering by design’ enables the construction of ‘living machines’. These ‘machines’, as biological machines, are expected to display certain properties of life, such as adapting to changing environments and acting in a situated way. This paper proposes that a tension exists between the expectations placed on biological artefacts and the notion of producing such systems by means of engineering; this tension makes it seem implausible that biological systems, especially (...) those with properties characteristic of living beings, can in fact be produced using the specific methods of engineering. We do not claim that engineering techniques have nothing to contribute to the biotechnological construction of biological artefacts. However, drawing on Descartes’s and Kant’s thinking on the relationship between the organism and the machine, we show that it is considerably more plausible to assume that distinctively biological artefacts emerge within a paradigm different from the paradigm of the Cartesian machine that underlies the engineering approach. We close by calling for increased attention to be paid to approaches within molecular biology and chemistry that rest on conceptions different from those of synthetic biology’s engineering paradigm. (shrink)